DK0950048T3 - 1-phenylalkyl-1,2,3,6-tetrahydropyridiner til behandling af Alzheimers sygdom - Google Patents
1-phenylalkyl-1,2,3,6-tetrahydropyridiner til behandling af Alzheimers sygdomInfo
- Publication number
- DK0950048T3 DK0950048T3 DK97951323T DK97951323T DK0950048T3 DK 0950048 T3 DK0950048 T3 DK 0950048T3 DK 97951323 T DK97951323 T DK 97951323T DK 97951323 T DK97951323 T DK 97951323T DK 0950048 T3 DK0950048 T3 DK 0950048T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- alkoxy
- amino
- pct
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9615335A FR2757160B1 (fr) | 1996-12-13 | 1996-12-13 | 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
PCT/FR1997/002286 WO1998025903A1 (fr) | 1996-12-13 | 1997-12-12 | 1-phenylalkyl-1,2,3,6-tetrahydropyridines pour le traitement de la maladie d'alzheimer |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0950048T3 true DK0950048T3 (da) | 2001-09-24 |
Family
ID=9498641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97951323T DK0950048T3 (da) | 1996-12-13 | 1997-12-12 | 1-phenylalkyl-1,2,3,6-tetrahydropyridiner til behandling af Alzheimers sygdom |
Country Status (31)
Country | Link |
---|---|
US (1) | US6034090A (cs) |
EP (1) | EP0950048B1 (cs) |
JP (1) | JP3881384B2 (cs) |
KR (1) | KR100560358B1 (cs) |
CN (1) | CN1129579C (cs) |
AT (1) | ATE202561T1 (cs) |
AU (1) | AU730143B2 (cs) |
BR (1) | BR9713916A (cs) |
CA (1) | CA2275353C (cs) |
CY (1) | CY2274B1 (cs) |
CZ (1) | CZ289789B6 (cs) |
DE (1) | DE69705429T2 (cs) |
DK (1) | DK0950048T3 (cs) |
EE (1) | EE03763B1 (cs) |
ES (1) | ES2160977T3 (cs) |
FR (1) | FR2757160B1 (cs) |
GR (1) | GR3036643T3 (cs) |
HU (1) | HU224347B1 (cs) |
IL (1) | IL130003A (cs) |
IS (1) | IS1969B (cs) |
NO (1) | NO312720B1 (cs) |
NZ (1) | NZ336033A (cs) |
PL (1) | PL190789B1 (cs) |
PT (1) | PT950048E (cs) |
RS (1) | RS49807B (cs) |
RU (1) | RU2189975C2 (cs) |
SI (1) | SI0950048T1 (cs) |
SK (1) | SK283331B6 (cs) |
TR (1) | TR199901291T2 (cs) |
UA (1) | UA52707C2 (cs) |
WO (1) | WO1998025903A1 (cs) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2763847B1 (fr) * | 1997-05-28 | 2003-06-06 | Sanofi Sa | Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1 |
UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
FR2832405B1 (fr) | 2001-11-19 | 2004-12-10 | Sanofi Synthelabo | Tetrahydropyridyl-alkyl-heterocycles azotes, procede pour leur preparation et compositions pharmaceutiques les contenant |
RU2248203C2 (ru) * | 2003-02-14 | 2005-03-20 | Общество С Ограниченной Ответственностью "Научно-Производственное Объединение "Фарматрон" | Церебропротекторное и ноотропное лекарственное средство "ноотрил" в таблетках, покрытых оболочкой |
RU2366655C2 (ru) * | 2003-03-14 | 2009-09-10 | Оно Фармасьютикал Ко., Лтд. | Азотсодержащие гетероциклические производные и лекарственные средства, содержащие их в качестве активного ингредиента |
RU2376761C1 (ru) * | 2008-08-06 | 2009-12-27 | Закрытое акционерное общество "АЛЬФА-ТЭК" | Антисептическое и фунгицидное средство |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1321701A (en) * | 1969-10-01 | 1973-06-27 | Continental Pharma | Amino-alcohols their salts and process for prepairing the same |
IE34545B1 (en) * | 1969-10-01 | 1975-06-11 | Continental Pharma | Amino-alcohols,their salts and process for preparing the same |
FR2650505B1 (fr) * | 1989-08-07 | 1994-06-03 | Midy Spa | Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale |
FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
HU211019B (en) * | 1991-12-02 | 1995-09-28 | Richter Gedeon Vegyeszet | Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds |
-
1996
- 1996-12-13 FR FR9615335A patent/FR2757160B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-12 RS YUP-243/99A patent/RS49807B/sr unknown
- 1997-12-12 WO PCT/FR1997/002286 patent/WO1998025903A1/fr not_active Application Discontinuation
- 1997-12-12 IL IL13000397A patent/IL130003A/en not_active IP Right Cessation
- 1997-12-12 PL PL334071A patent/PL190789B1/pl unknown
- 1997-12-12 SK SK786-99A patent/SK283331B6/sk unknown
- 1997-12-12 DK DK97951323T patent/DK0950048T3/da active
- 1997-12-12 HU HU0001185A patent/HU224347B1/hu not_active IP Right Cessation
- 1997-12-12 AU AU54893/98A patent/AU730143B2/en not_active Ceased
- 1997-12-12 SI SI9730187T patent/SI0950048T1/xx unknown
- 1997-12-12 US US09/331,006 patent/US6034090A/en not_active Expired - Fee Related
- 1997-12-12 PT PT97951323T patent/PT950048E/pt unknown
- 1997-12-12 EP EP97951323A patent/EP0950048B1/fr not_active Expired - Lifetime
- 1997-12-12 DE DE69705429T patent/DE69705429T2/de not_active Expired - Fee Related
- 1997-12-12 AT AT97951323T patent/ATE202561T1/de not_active IP Right Cessation
- 1997-12-12 BR BR9713916-5A patent/BR9713916A/pt not_active Application Discontinuation
- 1997-12-12 CA CA002275353A patent/CA2275353C/en not_active Expired - Fee Related
- 1997-12-12 ES ES97951323T patent/ES2160977T3/es not_active Expired - Lifetime
- 1997-12-12 TR TR1999/01291T patent/TR199901291T2/xx unknown
- 1997-12-12 CN CN97180581A patent/CN1129579C/zh not_active Expired - Fee Related
- 1997-12-12 RU RU99115083/04A patent/RU2189975C2/ru not_active IP Right Cessation
- 1997-12-12 NZ NZ336033A patent/NZ336033A/xx unknown
- 1997-12-12 KR KR1019997005203A patent/KR100560358B1/ko not_active Expired - Fee Related
- 1997-12-12 JP JP52632098A patent/JP3881384B2/ja not_active Expired - Fee Related
- 1997-12-12 CZ CZ19992113A patent/CZ289789B6/cs not_active IP Right Cessation
- 1997-12-12 EE EEP199900237A patent/EE03763B1/xx not_active IP Right Cessation
- 1997-12-12 UA UA99063286A patent/UA52707C2/uk unknown
-
1999
- 1999-06-10 IS IS5075A patent/IS1969B/is unknown
- 1999-06-11 NO NO19992869A patent/NO312720B1/no unknown
-
2001
- 2001-09-18 GR GR20010401501T patent/GR3036643T3/el not_active IP Right Cessation
-
2002
- 2002-05-15 CY CY0200027A patent/CY2274B1/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2225746A1 (en) | 4-aryl-1-phenylalkyl-1,2,3,6-tetrahydropyridines having neurotrophic and neuroprotective activity | |
PT1000035E (pt) | 6-fenilfenantridinas substituidas | |
FR2844268B1 (fr) | Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent | |
NO995245D0 (no) | Anvendelse av tetrahydropyridinderivater for fremstilling av medisiner for Õ behandle sykdommer som bevirker demyelinisering | |
NO20054340L (no) | Nye sammenkoplede heterocykler og deres anvendelse | |
DK0950048T3 (da) | 1-phenylalkyl-1,2,3,6-tetrahydropyridiner til behandling af Alzheimers sygdom | |
CO4980891A1 (es) | Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer | |
NO992870L (no) | Difenylalkyl-tetrahydropyridiner, fremgangsmåter for deres fremstilling og farmasöytiske blandinger inneholdende dem | |
NO944722L (no) | 3-(fenylalkylaminoalkyloksy)-5-fenylpyrazol-forbindelser samt fremgangsmåter og mellomprodukter for deres fremstilling, og legemidler som inneholder disse forbindelsene |