DK0882010T3 - Farmaceutiske midler indeholdende perfluoralkylholdige metalkomplekser - Google Patents

Farmaceutiske midler indeholdende perfluoralkylholdige metalkomplekser

Info

Publication number
DK0882010T3
DK0882010T3 DK97903278T DK97903278T DK0882010T3 DK 0882010 T3 DK0882010 T3 DK 0882010T3 DK 97903278 T DK97903278 T DK 97903278T DK 97903278 T DK97903278 T DK 97903278T DK 0882010 T3 DK0882010 T3 DK 0882010T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical agents
metal complexes
formula
perfluoroalkyl
agents containing
Prior art date
Application number
DK97903278T
Other languages
English (en)
Inventor
Johannes Platzek
Ulrich Niedballa
Bernd Raduechel
Wolfgang Schlecker
Hanns-Joachim Weinmann
Thomas Frenzel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0882010T3 publication Critical patent/DK0882010T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
DK97903278T 1996-02-23 1997-02-14 Farmaceutiske midler indeholdende perfluoralkylholdige metalkomplekser DK0882010T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19608278A DE19608278A1 (de) 1996-02-23 1996-02-23 Pharmazeutische Mittel enthaltend perfluoralkylhaltige Metallkomplexe, und ihre Verwendung in der Tumortherapie und interventioniellen Radiologie
PCT/EP1997/000684 WO1997030969A1 (de) 1996-02-23 1997-02-14 Pharmazeutische mittel enthaltend perfluoralkylhaltige metallkomplexe und ihre verwendung in der tumortherapie und interventionellen radiologie

Publications (1)

Publication Number Publication Date
DK0882010T3 true DK0882010T3 (da) 2001-08-20

Family

ID=7787153

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97903278T DK0882010T3 (da) 1996-02-23 1997-02-14 Farmaceutiske midler indeholdende perfluoralkylholdige metalkomplekser

Country Status (14)

Country Link
EP (1) EP0882010B1 (da)
JP (1) JP2000504736A (da)
AT (1) ATE200894T1 (da)
AU (1) AU1769297A (da)
CA (1) CA2247253A1 (da)
DE (2) DE19608278A1 (da)
DK (1) DK0882010T3 (da)
ES (1) ES2158493T3 (da)
GR (1) GR3036306T3 (da)
NO (1) NO323547B1 (da)
PT (1) PT882010E (da)
TW (1) TW477699B (da)
WO (1) WO1997030969A1 (da)
ZA (1) ZA971537B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919433A (en) * 1996-12-04 1999-07-06 Schering Aktiengesellschaft Macrocyclic metal complex carboxylic acids, their use as well as process for their production
DE19729013A1 (de) * 1997-07-03 1999-02-04 Schering Ag Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
DE19731591C2 (de) * 1997-07-17 1999-09-16 Schering Ag Pharmazeutische Mittel enthaltend perfluoralkylgruppenhaltige Trijodaromaten und ihre Verwendung in der Tumortherapie und interventionellen Radiologie
US6342598B1 (en) 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
US6461587B1 (en) 1999-03-22 2002-10-08 Schering Aktiengesellschaft Perfluoroalkylamides, their production and their use in diagnosis
DE19914101C1 (de) * 1999-03-22 2000-10-12 Schering Ag Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung
US6676928B2 (en) 2000-08-11 2004-01-13 Schering Aktiengesellschaft Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use
WO2003013610A2 (en) * 2001-08-03 2003-02-20 Glaxo Group Limited Surfactant compounds and uses thereof
WO2004006934A2 (de) * 2002-07-10 2004-01-22 Hans Robert Kalbitzer 1,4,7,10-tetraazacyclododecane als modulatoren des guanin-nukleotid bindenden roteins zur behandlung von tumoren
DE102005008309A1 (de) * 2005-02-17 2006-08-24 Schering Ag Pharmazeutische Mittel enthaltend fluoralkylhaltige Metallkomplexe und Epothilone
ITMI20131225A1 (it) * 2013-07-22 2015-01-23 Miteni Spa Nuovi composti organici fluorurati, procedimento per la loro preparazione e loro uso come intermedi di sintesi
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
EP3544964B1 (en) 2016-11-28 2020-06-17 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
AU2019382881A1 (en) 2018-11-23 2021-05-20 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
JP2024020674A (ja) * 2021-01-06 2024-02-15 Ａｇｃ株式会社 ペプチド

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2803869C2 (de) * 1978-01-30 1983-12-29 Ethicon, Inc., 08876 Somerville, N.J. Injizierbare Embolisations- und Okklusionslösung
JPS59130812A (ja) * 1983-01-14 1984-07-27 Green Cross Corp:The 癌化学療法補助剤
JPS59130813A (ja) * 1983-01-14 1984-07-27 Green Cross Corp:The 癌化学療法補助剤
JP2657393B2 (ja) * 1988-05-18 1997-09-24 日本化薬株式会社 化学塞栓療法剤
FR2682110B1 (fr) * 1991-10-02 1995-05-24 Atta Ligands amphiphiles perfluoroalkyles leurs complexes metalliques et leurs utilisations dans des preparations a usage therapeutique.
WO1993018795A1 (en) * 1992-03-19 1993-09-30 Daikin Industries, Ltd. Mri contrast medium and diagnostic method
US5401493A (en) * 1993-03-26 1995-03-28 Molecular Biosystems, Inc. Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same

Also Published As

Publication number Publication date
DE19608278A1 (de) 1997-08-28
ES2158493T3 (es) 2001-09-01
NO323547B1 (no) 2007-06-11
PT882010E (pt) 2001-10-30
EP0882010B1 (de) 2001-05-02
JP2000504736A (ja) 2000-04-18
NO983875D0 (no) 1998-08-21
NO983875L (no) 1998-10-22
ATE200894T1 (de) 2001-05-15
TW477699B (en) 2002-03-01
ZA971537B (en) 1997-10-30
DE59703468D1 (de) 2001-06-07
GR3036306T3 (en) 2001-10-31
AU1769297A (en) 1997-09-10
WO1997030969A1 (de) 1997-08-28
CA2247253A1 (en) 1997-08-28
EP0882010A1 (de) 1998-12-09

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