AU1769297A - Pharmaceutical agents containing perfluoroalkyl-containing metal complexes and the use thereof in tumour therapy and interventional radiology - Google Patents
Pharmaceutical agents containing perfluoroalkyl-containing metal complexes and the use thereof in tumour therapy and interventional radiologyInfo
- Publication number
- AU1769297A AU1769297A AU17692/97A AU1769297A AU1769297A AU 1769297 A AU1769297 A AU 1769297A AU 17692/97 A AU17692/97 A AU 17692/97A AU 1769297 A AU1769297 A AU 1769297A AU 1769297 A AU1769297 A AU 1769297A
- Authority
- AU
- Australia
- Prior art keywords
- pharmaceutical agents
- metal complexes
- interventional radiology
- tumour therapy
- agents containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to pharmaceutical agents containing perfluoroalkylated metal complexes of the general formula (I) RF-L-A and the use thereof in tumour therapy and interventional radiology, in which formula RF is a perfluorinated, straight-chain or branched carbon chain with the formula -CnF2nX, in which X is a terminal fluorine, chlorine, bromine, iodine or hydrogen atom and n represents the numbers 4-30, L is a binding group, and A is a metal complex or the salts thereof of organic and/or inorganic bases or amino acids or amino acid amides. L and A are defined in detail in the description.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19608278A DE19608278A1 (en) | 1996-02-23 | 1996-02-23 | Pharmaceutical compositions containing perfluoroalkyl-containing metal complexes, and their use in tumor therapy and interventional radiology |
DE19608278 | 1996-02-23 | ||
PCT/EP1997/000684 WO1997030969A1 (en) | 1996-02-23 | 1997-02-14 | Pharmaceutical agents containing perfluoroalkyl-containing metal complexes and the use thereof in tumour therapy and interventional radiology |
Publications (1)
Publication Number | Publication Date |
---|---|
AU1769297A true AU1769297A (en) | 1997-09-10 |
Family
ID=7787153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU17692/97A Abandoned AU1769297A (en) | 1996-02-23 | 1997-02-14 | Pharmaceutical agents containing perfluoroalkyl-containing metal complexes and the use thereof in tumour therapy and interventional radiology |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0882010B1 (en) |
JP (1) | JP2000504736A (en) |
AT (1) | ATE200894T1 (en) |
AU (1) | AU1769297A (en) |
CA (1) | CA2247253A1 (en) |
DE (2) | DE19608278A1 (en) |
DK (1) | DK0882010T3 (en) |
ES (1) | ES2158493T3 (en) |
GR (1) | GR3036306T3 (en) |
NO (1) | NO323547B1 (en) |
PT (1) | PT882010E (en) |
TW (1) | TW477699B (en) |
WO (1) | WO1997030969A1 (en) |
ZA (1) | ZA971537B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5919433A (en) * | 1996-12-04 | 1999-07-06 | Schering Aktiengesellschaft | Macrocyclic metal complex carboxylic acids, their use as well as process for their production |
DE19729013A1 (en) * | 1997-07-03 | 1999-02-04 | Schering Ag | Oligomeric, perfluoroalkyl-containing compounds, processes for their preparation and their use in NMR diagnostics |
DE19731591C2 (en) * | 1997-07-17 | 1999-09-16 | Schering Ag | Pharmaceutical compositions containing triiodoaromatics containing perfluoroalkyl groups and their use in tumor therapy and interventional radiology |
US6342598B1 (en) | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
US6461587B1 (en) | 1999-03-22 | 2002-10-08 | Schering Aktiengesellschaft | Perfluoroalkylamides, their production and their use in diagnosis |
DE19914101C1 (en) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoroalkylamides, their preparation and their use in diagnostics |
US6676928B2 (en) | 2000-08-11 | 2004-01-13 | Schering Aktiengesellschaft | Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use |
DE10040858C2 (en) * | 2000-08-11 | 2003-12-18 | Schering Ag | Perfluoroalkyl-containing complexes with polar residues, process for their preparation and their use |
CA2456052A1 (en) | 2001-08-03 | 2003-02-20 | Glaxo Group Limited | Surfactant compounds and uses thereof |
WO2004006934A2 (en) * | 2002-07-10 | 2004-01-22 | Hans Robert Kalbitzer | 1,4,7,10-tetraazacyclododecanes as modulators of the guanine-binding protein for treating tumours |
DE102005008309A1 (en) * | 2005-02-17 | 2006-08-24 | Schering Ag | Pharmaceutical agents containing fluoroalkyl-containing metal complexes and epothilones |
ITMI20131225A1 (en) * | 2013-07-22 | 2015-01-23 | Miteni Spa | NEW FLUORURED ORGANIC COMPOUNDS, PROCEDURE FOR THEIR PREPARATION AND THEIR USE AS INTERMEDIATE SUMMARY |
EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
WO2018096082A1 (en) | 2016-11-28 | 2018-05-31 | Bayer Pharma Aktiengesellschaft | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging |
MX2021006024A (en) | 2018-11-23 | 2021-07-06 | Bayer Ag | Formulation of contrast media and process of preparation thereof. |
JP2024020674A (en) * | 2021-01-06 | 2024-02-15 | Agc株式会社 | peptide |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2803869C2 (en) * | 1978-01-30 | 1983-12-29 | Ethicon, Inc., 08876 Somerville, N.J. | Injectable embolization and occlusion solution |
JPS59130813A (en) * | 1983-01-14 | 1984-07-27 | Green Cross Corp:The | Adminiculum for chemotherapy of cancer |
JPS59130812A (en) * | 1983-01-14 | 1984-07-27 | Green Cross Corp:The | Adminiculum for chemotherapy of cancer |
JP2657393B2 (en) * | 1988-05-18 | 1997-09-24 | 日本化薬株式会社 | Chemoembolization agent |
FR2682110B1 (en) * | 1991-10-02 | 1995-05-24 | Atta | PERFLUOROALKYL AMPHIPHILIC LIGANDS, THEIR METAL COMPLEXES AND THEIR USES IN PREPARATIONS FOR THERAPEUTIC USE. |
WO1993018795A1 (en) * | 1992-03-19 | 1993-09-30 | Daikin Industries, Ltd. | Mri contrast medium and diagnostic method |
US5401493A (en) * | 1993-03-26 | 1995-03-28 | Molecular Biosystems, Inc. | Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same |
-
1996
- 1996-02-23 DE DE19608278A patent/DE19608278A1/en not_active Withdrawn
-
1997
- 1997-02-14 EP EP97903278A patent/EP0882010B1/en not_active Expired - Lifetime
- 1997-02-14 DE DE59703468T patent/DE59703468D1/en not_active Expired - Fee Related
- 1997-02-14 ES ES97903278T patent/ES2158493T3/en not_active Expired - Lifetime
- 1997-02-14 AU AU17692/97A patent/AU1769297A/en not_active Abandoned
- 1997-02-14 DK DK97903278T patent/DK0882010T3/en active
- 1997-02-14 JP JP9529766A patent/JP2000504736A/en not_active Ceased
- 1997-02-14 AT AT97903278T patent/ATE200894T1/en not_active IP Right Cessation
- 1997-02-14 PT PT97903278T patent/PT882010E/en unknown
- 1997-02-14 CA CA002247253A patent/CA2247253A1/en not_active Abandoned
- 1997-02-14 WO PCT/EP1997/000684 patent/WO1997030969A1/en active IP Right Grant
- 1997-02-21 ZA ZA9701537A patent/ZA971537B/en unknown
- 1997-02-22 TW TW086102174A patent/TW477699B/en not_active IP Right Cessation
-
1998
- 1998-08-21 NO NO19983875A patent/NO323547B1/en unknown
-
2001
- 2001-07-31 GR GR20010401156T patent/GR3036306T3/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE59703468D1 (en) | 2001-06-07 |
DK0882010T3 (en) | 2001-08-20 |
CA2247253A1 (en) | 1997-08-28 |
ZA971537B (en) | 1997-10-30 |
PT882010E (en) | 2001-10-30 |
EP0882010B1 (en) | 2001-05-02 |
TW477699B (en) | 2002-03-01 |
GR3036306T3 (en) | 2001-10-31 |
JP2000504736A (en) | 2000-04-18 |
WO1997030969A1 (en) | 1997-08-28 |
DE19608278A1 (en) | 1997-08-28 |
NO983875L (en) | 1998-10-22 |
ES2158493T3 (en) | 2001-09-01 |
NO323547B1 (en) | 2007-06-11 |
ATE200894T1 (en) | 2001-05-15 |
EP0882010A1 (en) | 1998-12-09 |
NO983875D0 (en) | 1998-08-21 |
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