DK0815138T3 - Stabil polymeriseret hæmoglobin-blod-erstatning - Google Patents

Stabil polymeriseret hæmoglobin-blod-erstatning

Info

Publication number
DK0815138T3
DK0815138T3 DK96909855T DK96909855T DK0815138T3 DK 0815138 T3 DK0815138 T3 DK 0815138T3 DK 96909855 T DK96909855 T DK 96909855T DK 96909855 T DK96909855 T DK 96909855T DK 0815138 T3 DK0815138 T3 DK 0815138T3
Authority
DK
Denmark
Prior art keywords
hemoglobin
solution
blood
polymerized
blood cells
Prior art date
Application number
DK96909855T
Other languages
Danish (da)
English (en)
Inventor
Carl W Rausch
Maria S Gawryl
Robert A Houtchens
Anthony J Laccetti
William R Light
Edward E Jacobs Jr
Original Assignee
Biopure Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/409,337 external-priority patent/US5854209A/en
Priority claimed from US08/478,004 external-priority patent/US5753616A/en
Priority claimed from US08/487,288 external-priority patent/US5895810A/en
Priority claimed from US08/471,583 external-priority patent/US5691452A/en
Priority claimed from US08/484,775 external-priority patent/US5955581A/en
Application filed by Biopure Corp filed Critical Biopure Corp
Application granted granted Critical
Publication of DK0815138T3 publication Critical patent/DK0815138T3/da

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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
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    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B32B15/09—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyesters
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
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    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B32B2377/00—Polyamides
DK96909855T 1995-03-23 1996-03-22 Stabil polymeriseret hæmoglobin-blod-erstatning DK0815138T3 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US08/409,337 US5854209A (en) 1995-03-23 1995-03-23 Method for oxygenating tissue having reduced red blood cell flow
US08/458,916 US5840852A (en) 1995-03-23 1995-06-02 Method for producing ultrapure stable polmerized hemoglobin blood-substitute
US47349795A 1995-06-07 1995-06-07
US08/478,004 US5753616A (en) 1986-11-10 1995-06-07 Method for producing a stable polymerized hemoglobin blood-substitute
US08/487,288 US5895810A (en) 1995-03-23 1995-06-07 Stable polymerized hemoglobin and use thereof
US08/471,583 US5691452A (en) 1995-03-23 1995-06-07 Method for preserving a hemoglobin blood substitute
US08/484,775 US5955581A (en) 1986-11-10 1995-06-07 Method for producing a stable polymerized hemoglobin blood-substitute
PCT/US1996/004030 WO1996029346A1 (fr) 1995-03-23 1996-03-22 Succedane du sang polymerise stable a base d'hemoglobine

Publications (1)

Publication Number Publication Date
DK0815138T3 true DK0815138T3 (da) 2002-12-23

Family

ID=27569756

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96909855T DK0815138T3 (da) 1995-03-23 1996-03-22 Stabil polymeriseret hæmoglobin-blod-erstatning

Country Status (11)

Country Link
EP (5) EP1094078A3 (fr)
JP (2) JP4382877B2 (fr)
AT (2) ATE447324T1 (fr)
AU (1) AU705225B2 (fr)
CA (1) CA2215697C (fr)
DE (1) DE69623267T2 (fr)
DK (1) DK0815138T3 (fr)
ES (1) ES2179188T3 (fr)
NZ (1) NZ305258A (fr)
PT (1) PT815138E (fr)
WO (1) WO1996029346A1 (fr)

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WO2006108047A2 (fr) * 2005-04-05 2006-10-12 Biopure Corporation Solutions oxygenees d'hemoglobine polymerisee et leurs utilisations pour la visualisation de tissus oxygenated polymerized hemoglobin solutions and their uses for tissue visualization
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US7989593B1 (en) * 2010-05-27 2011-08-02 Bing Lou Wong Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
ES2959120T3 (es) 2010-08-25 2024-02-20 Hemanext Inc Método para potenciar la calidad y la supervivencia de glóbulos rojos durante el almacenamiento
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EP2682407B1 (fr) 2011-03-01 2016-09-14 Chuo University Complexe hémoglobine-albumine, et dispositif d'expansion de plasma artificiel et vecteur d'oxygène artificiel, chacun contenant le complexe hémoglobine-albumine
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KR20190017747A (ko) 2016-05-27 2019-02-20 뉴 헬스 사이언시즈 인코포레이티드 혐기성 혈액 저장 및 병원체 불활성화 방법
JP7016124B2 (ja) 2016-07-06 2022-02-04 学校法人 中央大学 虚血性疾患の治療剤
JP2020533416A (ja) * 2017-09-12 2020-11-19 メディカル・テクノロジー・アソシエイツ・ザ・セカンド・インコーポレイテッドＭｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｙ Ａｓｓｏｃｉａｔｅｓ Ｉｉ， Ｉｎｃ． エンドトキシンフリーヘモグロビン系薬物物質を製造するためのシステム及び方法、並びに、エンドトキシンフリータンパク質の精製方法
CN110128531B (zh) * 2019-05-17 2022-03-08 润方（北京）生物医药研究院有限公司 一种无碳酸酐酶血红蛋白的制备方法
WO2021072194A1 (fr) * 2019-10-11 2021-04-15 Medical Technology Associates Ii, Inc. Compositions d'hémoglobine stabilisées et leurs formulations pharmaceutiques
CN112782319A (zh) * 2021-02-09 2021-05-11 北京欧德福瑞医药科技发展有限公司 一种咖啡酸苯乙酯的分析方法
WO2023163750A1 (fr) * 2022-02-28 2023-08-31 Ohio State Innovation Foundation Hémoglobine polymérisée fractionnée en taille par filtration à écoulement tangentiel avec de faibles taux d'auto-oxydation

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EP1211261A2 (fr) 2002-06-05
EP1094079A3 (fr) 2001-05-02
AU5322796A (en) 1996-10-08
CA2215697C (fr) 2009-08-18
EP1211261A3 (fr) 2004-03-17
JPH11502821A (ja) 1999-03-09
JP2007260393A (ja) 2007-10-11
PT815138E (pt) 2002-12-31
EP0815138B1 (fr) 2002-08-28
EP1093720A1 (fr) 2001-04-25
DE69623267T2 (de) 2003-04-17
NZ305258A (en) 2000-10-27
EP1094078A3 (fr) 2001-05-02
ATE447324T1 (de) 2009-11-15
AU705225B2 (en) 1999-05-20
EP1094078A2 (fr) 2001-04-25
ATE222926T1 (de) 2002-09-15
EP1093720B1 (fr) 2009-11-04
EP0815138A1 (fr) 1998-01-07
DE69623267D1 (de) 2002-10-02
WO1996029346A1 (fr) 1996-09-26
EP1094079A2 (fr) 2001-04-25
JP4382877B2 (ja) 2009-12-16
ES2179188T3 (es) 2003-01-16
CA2215697A1 (fr) 1996-09-26

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