DE69821740D1 - Behandlung von hämoglobin enthaltenden erythrozyten mit stickstoffoxyd - Google Patents

Behandlung von hämoglobin enthaltenden erythrozyten mit stickstoffoxyd

Info

Publication number
DE69821740D1
DE69821740D1 DE69821740T DE69821740T DE69821740D1 DE 69821740 D1 DE69821740 D1 DE 69821740D1 DE 69821740 T DE69821740 T DE 69821740T DE 69821740 T DE69821740 T DE 69821740T DE 69821740 D1 DE69821740 D1 DE 69821740D1
Authority
DE
Germany
Prior art keywords
hemoglobin
oxyd
nitrogen
erythrocytes
containing erythrocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69821740T
Other languages
English (en)
Other versions
DE69821740T2 (de
Inventor
Takashi Yonetani
Antonio Tsuneshige
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FORYOU CORP., YOKOHAMA, KANAGAWA, JP
Original Assignee
Foryou Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foryou Corp filed Critical Foryou Corp
Publication of DE69821740D1 publication Critical patent/DE69821740D1/de
Application granted granted Critical
Publication of DE69821740T2 publication Critical patent/DE69821740T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
DE69821740T 1997-07-03 1998-07-03 Behandlung von hämoglobin enthaltenden erythrozyten mit stickstoffoxyd Expired - Fee Related DE69821740T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5168097P 1997-07-03 1997-07-03
US51680P 1997-07-03
PCT/JP1998/003002 WO1999001146A1 (en) 1997-07-03 1998-07-03 Treatment of hemoglobin containing erythrocytes with nitric oxide

Publications (2)

Publication Number Publication Date
DE69821740D1 true DE69821740D1 (de) 2004-03-25
DE69821740T2 DE69821740T2 (de) 2005-03-17

Family

ID=21972754

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69821740T Expired - Fee Related DE69821740T2 (de) 1997-07-03 1998-07-03 Behandlung von hämoglobin enthaltenden erythrozyten mit stickstoffoxyd

Country Status (7)

Country Link
US (1) US6087087A (de)
EP (1) EP0948337B1 (de)
JP (1) JP3568541B2 (de)
AT (1) ATE259644T1 (de)
CA (1) CA2264792A1 (de)
DE (1) DE69821740T2 (de)
WO (1) WO1999001146A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2680378C (en) * 1999-08-02 2013-09-24 Duke University Method for determining physiological effects of hemoglobin
US20030228564A1 (en) * 2001-05-30 2003-12-11 Edrich Richard Alan Nitric oxide in a pathogen inactivation process
EP1472021A4 (de) * 2002-01-11 2008-04-16 David R Whitlock Ammoniak oxidierende bakterien enthaltende zusammensetzungen und verwendungsverfahren dafür
WO2003102575A1 (en) * 2002-05-29 2003-12-11 Duke University Measuring nitric oxide in blood gases and treatments based thereon
US8075922B2 (en) 2002-12-12 2011-12-13 Montana State University-Bozeman Method of co-infusing a deoxygenated hemoglobin containing blood substitute and inorganic nitrite
US20070148136A1 (en) * 2003-09-26 2007-06-28 Whitlock David R Methods of using ammonia oxidizing bacteria
US20080248012A1 (en) * 2004-01-29 2008-10-09 Keio University Erythrocyte Function Modifying Substance
WO2006096774A2 (en) * 2005-03-07 2006-09-14 Sangart, Inc. Composition and methods for delivering carbon monoxide (co) and nitric ozide (no) co to tissue using heme proteins as carriers
US9199026B2 (en) * 2011-01-07 2015-12-01 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
BR112013023740A2 (pt) 2011-03-16 2016-08-02 Dynasil Biomedical Corp métodos e materiais para prolongamento da armazenagem útil de preparações de glóbulo vermelho e preparações de plaqueta
WO2013070592A1 (en) * 2011-11-07 2013-05-16 The General Hospital Corporation Treatment of red blood cells
CA2897426A1 (en) 2012-01-09 2013-07-18 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
GB201207543D0 (en) * 2012-05-01 2012-06-13 Haemair Ltd Treatment of transfusion blood
ES2900298T3 (es) * 2013-02-28 2022-03-16 Hemanext Inc Dispositivo de agotamiento de gas para productos sanguíneos
WO2015179602A1 (en) * 2014-05-21 2015-11-26 Albert Einstein College Of Medicine, Inc. Compositions and methods for enhancing red blood cell storage time and survivability using nitric oxide releasing hybrid hydrogel nanoparticles
US10194871B2 (en) 2015-09-25 2019-02-05 Sanmina Corporation Vehicular health monitoring system and method
US10973470B2 (en) 2015-07-19 2021-04-13 Sanmina Corporation System and method for screening and prediction of severity of infection
US10736580B2 (en) 2016-09-24 2020-08-11 Sanmina Corporation System and method of a biosensor for detection of microvascular responses
US9788767B1 (en) 2015-09-25 2017-10-17 Sanmina Corporation System and method for monitoring nitric oxide levels using a non-invasive, multi-band biosensor
US10932727B2 (en) 2015-09-25 2021-03-02 Sanmina Corporation System and method for health monitoring including a user device and biosensor
US10321860B2 (en) 2015-07-19 2019-06-18 Sanmina Corporation System and method for glucose monitoring
US10750981B2 (en) 2015-09-25 2020-08-25 Sanmina Corporation System and method for health monitoring including a remote device
US10952682B2 (en) 2015-07-19 2021-03-23 Sanmina Corporation System and method of a biosensor for detection of health parameters
US9636457B2 (en) 2015-07-19 2017-05-02 Sanmina Corporation System and method for a drug delivery and biosensor patch
US10888280B2 (en) 2016-09-24 2021-01-12 Sanmina Corporation System and method for obtaining health data using a neural network
US10744261B2 (en) 2015-09-25 2020-08-18 Sanmina Corporation System and method of a biosensor for detection of vasodilation
US10945676B2 (en) 2015-09-25 2021-03-16 Sanmina Corporation System and method for blood typing using PPG technology
US10466783B2 (en) 2018-03-15 2019-11-05 Sanmina Corporation System and method for motion detection using a PPG sensor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU681999B2 (en) * 1992-02-07 1997-09-18 Vasogen Ireland Limited Method of increasing the concentration of nitric oxide in blood
US6197745B1 (en) * 1995-09-15 2001-03-06 Duke University Methods for producing nitrosated hemoglobins and therapeutic uses therefor
AU6150298A (en) * 1997-02-06 1998-08-26 Duke University Medical Center No-modified hemoglobins and uses therefor

Also Published As

Publication number Publication date
EP0948337A1 (de) 1999-10-13
US6087087A (en) 2000-07-11
JP2001507375A (ja) 2001-06-05
EP0948337B1 (de) 2004-02-18
WO1999001146A1 (en) 1999-01-14
JP3568541B2 (ja) 2004-09-22
CA2264792A1 (en) 1999-01-14
DE69821740T2 (de) 2005-03-17
ATE259644T1 (de) 2004-03-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: FORYOU CORP., YOKOHAMA, KANAGAWA, JP

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee