DK0777678T3 - Kombinatoriske PNA-biblioteker og forbedrede syntesemetoder - Google Patents

Kombinatoriske PNA-biblioteker og forbedrede syntesemetoder

Info

Publication number
DK0777678T3
DK0777678T3 DK95911848T DK95911848T DK0777678T3 DK 0777678 T3 DK0777678 T3 DK 0777678T3 DK 95911848 T DK95911848 T DK 95911848T DK 95911848 T DK95911848 T DK 95911848T DK 0777678 T3 DK0777678 T3 DK 0777678T3
Authority
DK
Denmark
Prior art keywords
peptide nucleic
nucleic acid
methods
synthesis methods
improved synthesis
Prior art date
Application number
DK95911848T
Other languages
Danish (da)
English (en)
Inventor
John Kiely
Kelly Sprankle
Phillip Dan Cook
Original Assignee
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Application granted granted Critical
Publication of DK0777678T3 publication Critical patent/DK0777678T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003—Peptide-nucleic acids (PNAs)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00592—Split-and-pool, mix-and-divide processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00729—Peptide nucleic acids [PNA]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95911848T 1994-02-23 1995-02-22 Kombinatoriske PNA-biblioteker og forbedrede syntesemetoder DK0777678T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/200,742 US5539083A (en) 1994-02-23 1994-02-23 Peptide nucleic acid combinatorial libraries and improved methods of synthesis
PCT/US1995/002182 WO1995023163A1 (en) 1994-02-23 1995-02-22 Pna combinatorial libraries and improved methods of synthesis

Publications (1)

Publication Number Publication Date
DK0777678T3 true DK0777678T3 (da) 2000-04-03

Family

ID=22742993

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95911848T DK0777678T3 (da) 1994-02-23 1995-02-22 Kombinatoriske PNA-biblioteker og forbedrede syntesemetoder

Country Status (9)

Country Link
US (5) US5539083A (https=)
EP (1) EP0777678B1 (https=)
JP (2) JPH09503523A (https=)
AT (1) ATE185572T1 (https=)
AU (1) AU684152B2 (https=)
CA (1) CA2183371C (https=)
DE (1) DE69512794T2 (https=)
DK (1) DK0777678T3 (https=)
WO (1) WO1995023163A1 (https=)

Families Citing this family (455)

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DE69512794D1 (de) 1999-11-18
JPH09503523A (ja) 1997-04-08
US6204326B1 (en) 2001-03-20
US5864010A (en) 1999-01-26
WO1995023163A1 (en) 1995-08-31
EP0777678A4 (https=) 1997-07-16
AU1926195A (en) 1995-09-11
US6756199B1 (en) 2004-06-29
CA2183371C (en) 2001-04-03
JPH11209393A (ja) 1999-08-03
AU684152B2 (en) 1997-12-04
DE69512794T2 (de) 2000-05-31
US5539083A (en) 1996-07-23
ATE185572T1 (de) 1999-10-15
EP0777678B1 (en) 1999-10-13
EP0777678A1 (en) 1997-06-11
CA2183371A1 (en) 1995-08-31
US5831014A (en) 1998-11-03

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