HUP0004739A1 - Presenilinekkel kölcsönhatásra képes fehérjéket kódoló nukleinsavak - Google Patents

Presenilinekkel kölcsönhatásra képes fehérjéket kódoló nukleinsavak

Info

Publication number
HUP0004739A1
HUP0004739A1 HU0004739A HUP0004739A HUP0004739A1 HU P0004739 A1 HUP0004739 A1 HU P0004739A1 HU 0004739 A HU0004739 A HU 0004739A HU P0004739 A HUP0004739 A HU P0004739A HU P0004739 A1 HUP0004739 A1 HU P0004739A1
Authority
HU
Hungary
Prior art keywords
presenilins
interacting
nucleic acids
proteins capable
acids coding
Prior art date
Application number
HU0004739A
Other languages
English (en)
Inventor
Alain Fournier
Luc Mercken
Marie-Francoise Paul
Laurent Pradier
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9712221A external-priority patent/FR2769021B1/fr
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0004739A1 publication Critical patent/HUP0004739A1/hu
Publication of HUP0004739A3 publication Critical patent/HUP0004739A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány tárgyát új nukleotid és peptidszekvenciák, valamintgyógyászati alkalmazásuk képezik. Részletesebben meghatározva, atalálmány tárgyát presenilinekkel kölcsönhatásra képes fehérjéketkódoló nukleinsavak képezik, valamint az említett fehérjék és azazokat tartalmazó készítmények előállítására szolgáló eljárás.é Ó
HU0004739A 1997-10-01 1998-09-30 Nucleic acids coding for proteins capable of interacting with presenilins HUP0004739A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9712221A FR2769021B1 (fr) 1997-10-01 1997-10-01 Acides nucleiques codant pour des proteines capables d'interagir avec les presenilines
US9493398P 1998-07-31 1998-07-31
PCT/FR1998/002093 WO1999016874A1 (fr) 1997-10-01 1998-09-30 Acides nucleiques codant pour des proteines capables d'interagir avec les presenilines

Publications (2)

Publication Number Publication Date
HUP0004739A1 true HUP0004739A1 (hu) 2001-05-28
HUP0004739A3 HUP0004739A3 (en) 2003-10-28

Family

ID=26233829

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004739A HUP0004739A3 (en) 1997-10-01 1998-09-30 Nucleic acids coding for proteins capable of interacting with presenilins

Country Status (10)

Country Link
EP (1) EP1021533A1 (hu)
JP (1) JP2001518294A (hu)
KR (1) KR20010030862A (hu)
CN (1) CN1272139A (hu)
AU (1) AU9354998A (hu)
CA (1) CA2305781A1 (hu)
HU (1) HUP0004739A3 (hu)
IL (1) IL135187A0 (hu)
NO (1) NO20001680L (hu)
WO (1) WO1999016874A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066745A2 (en) * 2000-03-03 2001-09-13 The Salk Institute For Biological Studies Presenilin/crk binding polypeptides (pcbp) and methods of use thereof
WO2002090541A1 (en) * 2001-05-03 2002-11-14 Murdoch Childrens Research Institute Determination of a genetic predisposition for behavioural disorders
JP2003012548A (ja) * 2001-06-27 2003-01-15 Japan Science & Technology Corp 医薬組成物
JP2003018991A (ja) 2001-06-27 2003-01-21 Japan Science & Technology Corp プレセニリン−２遺伝子エキソン５欠損型スプライシング異常の生成に関与する核酸
CN102206252A (zh) * 2010-10-25 2011-10-05 深圳华大基因科技有限公司 早老素5抑制因子抗原表位、抗早老素5抑制因子抗体及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000506375A (ja) * 1996-01-26 2000-05-30 エイチエスシー リサーチ アンド デベロップメント リミテッド パートナーシップ アルツハイマー病に関連する核酸およびタンパク質、ならびにその使用

Also Published As

Publication number Publication date
WO1999016874A1 (fr) 1999-04-08
NO20001680D0 (no) 2000-03-31
CA2305781A1 (fr) 1999-04-08
JP2001518294A (ja) 2001-10-16
IL135187A0 (en) 2001-05-20
HUP0004739A3 (en) 2003-10-28
CN1272139A (zh) 2000-11-01
KR20010030862A (ko) 2001-04-16
AU9354998A (en) 1999-04-23
NO20001680L (no) 2000-03-31
EP1021533A1 (fr) 2000-07-26

Similar Documents

Publication Publication Date Title
ATE182901T1 (de) Für androgen-rezeptor-protein kodierende dna
NO179253C (no) Rekombinant DNA-sekvens som koder for humant proapolipoprotein A-I, ekspresjonsvektorer, cellekulturer samt fremgangsmåte for fremstilling av proteinet
ZA91134B (en) New proteins produced by human lymphocytes,dna sequence encoding these proteins and their pharmaceutical and biological uses
ATE196164T1 (de) Gereinigte scytalidium lacassen und nukleinsäuren dafür kodierend
ATE185572T1 (de) Kombinatorische pna-bibliotheken und verbesserte syntheseverfahren
FI962247A (fi) Uudet apoptoosia muuntavat proteiinit, niitä koodaava DNA ja näiden käyttömenetelmät
DK0845032T3 (da) Isolerede nucleinsyremolekyler, peptider, der danner komplekser med MHC-molekyler HLA-A2, samt anvendelser
ATE195346T1 (de) Rekombinante dna moleküle die aminopeptidase enzyme kodieren und ihre anwendung für die herstellung von impfstoffen gegen helminth infektionen
ATE358725T1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
AUPP472398A0 (en) Protease susceptibility II
HUP9904414A2 (hu) A neuritin neurogén
AU7001994A (en) Mutant polypeptide of protein kinase c, nucleic acid sequences coding for said polypeptide and use thereof
IL116026A (en) Peptides capable of linking to the sh3 domain of gap, nucleotide sequences encoding the same, their preparation and uses
HUP0004739A1 (hu) Presenilinekkel kölcsönhatásra képes fehérjéket kódoló nukleinsavak
ATE271609T1 (de) Mch3, eine apoptosis-protease, kodierende nukleinsäuren und methoden zur verwendung
HUP0004605A1 (hu) Presenilinek és a béta-amiloid peptid vagy prekurzora közötti kölcsönhatás gátlására képes peptidek
HUP9702147A2 (hu) Humán DNáz I variánsok
HUP0300813A2 (hu) Gének, fehérjék és alkalmazásuk
HUP9802289A2 (hu) Limfocita specifikus interferon szabályozó faktor (LSIRF) polipeptideket kódoló gének
IL139272A0 (en) New peptide fragments for protein purification
HUP0203080A2 (hu) A PRV-1 gén és felhasználása
DE60026049D1 (de) POLYPEPTIDE MIT GLUCANOTRANSFERASE AKTIVITÄT UND DAFüR KODIERENDE NUKLEINSÄUREN
AU2001276385A1 (en) Nucleotide sequences which code for the lysr3 gene
GB2329896A (en) Enzyme and DNA sequence encoding same
LV12722A (lv) Prv-1 gene and the use thereof