ATE271609T1 - Mch3, eine apoptosis-protease, kodierende nukleinsäuren und methoden zur verwendung - Google Patents
Mch3, eine apoptosis-protease, kodierende nukleinsäuren und methoden zur verwendungInfo
- Publication number
- ATE271609T1 ATE271609T1 AT96939666T AT96939666T ATE271609T1 AT E271609 T1 ATE271609 T1 AT E271609T1 AT 96939666 T AT96939666 T AT 96939666T AT 96939666 T AT96939666 T AT 96939666T AT E271609 T1 ATE271609 T1 AT E271609T1
- Authority
- AT
- Austria
- Prior art keywords
- mch3
- nucleic acids
- methods
- acids encoding
- functional fragment
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 102100038902 Caspase-7 Human genes 0.000 title 1
- 101000741014 Homo sapiens Caspase-7 Proteins 0.000 title 1
- 108091005804 Peptidases Proteins 0.000 title 1
- 239000004365 Protease Substances 0.000 title 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
- 230000006907 apoptotic process Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
- C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Tea And Coffee (AREA)
- Confectionery (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/556,627 US6462175B1 (en) | 1995-11-13 | 1995-11-13 | Mch3, a novel apoptotic protease, nucleic acids encoding and methods of use |
| PCT/US1996/018118 WO1997018313A1 (en) | 1995-11-13 | 1996-11-12 | Mch3, an apoptotic protease, nucleic acids encoding and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE271609T1 true ATE271609T1 (de) | 2004-08-15 |
Family
ID=24222154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96939666T ATE271609T1 (de) | 1995-11-13 | 1996-11-12 | Mch3, eine apoptosis-protease, kodierende nukleinsäuren und methoden zur verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US6462175B1 (de) |
| EP (1) | EP0866866B1 (de) |
| JP (1) | JP2000500338A (de) |
| AT (1) | ATE271609T1 (de) |
| AU (1) | AU728859C (de) |
| CA (1) | CA2237618C (de) |
| DE (1) | DE69632963T2 (de) |
| NZ (1) | NZ322796A (de) |
| WO (1) | WO1997018313A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6060238A (en) * | 1995-02-13 | 2000-05-09 | The Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
| US6015665A (en) * | 1995-02-13 | 2000-01-18 | The Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
| US7097972B1 (en) | 1995-02-13 | 2006-08-29 | Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
| US7807783B1 (en) | 1995-04-03 | 2010-10-05 | The Regents Of The University Of Michigan | Methods and compositions for regulating FAS-associated apoptosis |
| US6747138B1 (en) | 1995-04-03 | 2004-06-08 | Regents Of The University Of Michigan | Methods and compositions for regulating Fas-associated apoptosis |
| US6462175B1 (en) * | 1995-11-13 | 2002-10-08 | Thomas Jefferson University | Mch3, a novel apoptotic protease, nucleic acids encoding and methods of use |
| ES2181197T3 (es) | 1997-04-25 | 2003-02-16 | Wyeth Corp | Isoformas de mort1 neuronal. |
| US6270980B1 (en) * | 1997-06-05 | 2001-08-07 | Idun Pharmaceuticals, Inc. | Rapid methods for identifying modifiers of cellular apoptosis activity |
| EP1232253A2 (de) * | 1999-11-16 | 2002-08-21 | Vertex Pharmaceuticals Incorporated | Caspase-7 enthaltende kristallisierbare zusammensetzungen |
| CA2513769A1 (en) * | 2003-01-28 | 2004-08-12 | Georgetown University | Method for evaluating the efficacy of certain cancer treatments |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6538121B1 (en) * | 1994-11-01 | 2003-03-25 | Human Genome Sciences, Inc. | Interleukin-1 β converting enzyme like apoptosis protease-3 and 4 |
| AU720077B2 (en) * | 1995-11-03 | 2000-05-25 | Vertex Pharmaceuticals Incorporated | DNA sequences encoding CMH-1, a cysteine protease involved in apoptosis |
| US6462175B1 (en) * | 1995-11-13 | 2002-10-08 | Thomas Jefferson University | Mch3, a novel apoptotic protease, nucleic acids encoding and methods of use |
-
1995
- 1995-11-13 US US08/556,627 patent/US6462175B1/en not_active Expired - Lifetime
-
1996
- 1996-11-12 NZ NZ322796A patent/NZ322796A/xx not_active IP Right Cessation
- 1996-11-12 CA CA2237618A patent/CA2237618C/en not_active Expired - Lifetime
- 1996-11-12 JP JP9518998A patent/JP2000500338A/ja active Pending
- 1996-11-12 AT AT96939666T patent/ATE271609T1/de not_active IP Right Cessation
- 1996-11-12 AU AU76782/96A patent/AU728859C/en not_active Expired
- 1996-11-12 WO PCT/US1996/018118 patent/WO1997018313A1/en not_active Ceased
- 1996-11-12 EP EP96939666A patent/EP0866866B1/de not_active Expired - Lifetime
- 1996-11-12 DE DE69632963T patent/DE69632963T2/de not_active Expired - Lifetime
-
1998
- 1998-09-29 US US09/163,099 patent/US6686459B1/en not_active Expired - Lifetime
-
2001
- 2001-08-31 US US09/944,851 patent/US20020102648A1/en not_active Abandoned
-
2003
- 2003-01-02 US US10/337,060 patent/US6716960B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0866866A1 (de) | 1998-09-30 |
| US20020102648A1 (en) | 2002-08-01 |
| AU728859B2 (en) | 2001-01-18 |
| DE69632963D1 (de) | 2004-08-26 |
| EP0866866B1 (de) | 2004-07-21 |
| CA2237618A1 (en) | 1997-05-22 |
| US6716960B2 (en) | 2004-04-06 |
| CA2237618C (en) | 2011-04-19 |
| NZ322796A (en) | 1999-06-29 |
| AU728859C (en) | 2003-01-09 |
| AU7678296A (en) | 1997-06-05 |
| JP2000500338A (ja) | 2000-01-18 |
| WO1997018313A1 (en) | 1997-05-22 |
| US6686459B1 (en) | 2004-02-03 |
| US20030119169A1 (en) | 2003-06-26 |
| DE69632963T2 (de) | 2005-07-28 |
| US6462175B1 (en) | 2002-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |