DK0696595T3 - Albuminfraktionering ved lav temperatur ved anvendelse af natriumcaprylat som et adskillelsesmiddel - Google Patents

Albuminfraktionering ved lav temperatur ved anvendelse af natriumcaprylat som et adskillelsesmiddel

Info

Publication number
DK0696595T3
DK0696595T3 DK95112061T DK95112061T DK0696595T3 DK 0696595 T3 DK0696595 T3 DK 0696595T3 DK 95112061 T DK95112061 T DK 95112061T DK 95112061 T DK95112061 T DK 95112061T DK 0696595 T3 DK0696595 T3 DK 0696595T3
Authority
DK
Denmark
Prior art keywords
albumin
sodium caprylate
amount
molecule
low temperature
Prior art date
Application number
DK95112061T
Other languages
English (en)
Inventor
Robert A Tenold
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0696595T3 publication Critical patent/DK0696595T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95112061T 1994-08-10 1995-08-01 Albuminfraktionering ved lav temperatur ved anvendelse af natriumcaprylat som et adskillelsesmiddel DK0696595T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/288,180 US5561115A (en) 1994-08-10 1994-08-10 Low temperature albumin fractionation using sodium caprylate as a partitioning agent

Publications (1)

Publication Number Publication Date
DK0696595T3 true DK0696595T3 (da) 1999-07-12

Family

ID=23106084

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95112061T DK0696595T3 (da) 1994-08-10 1995-08-01 Albuminfraktionering ved lav temperatur ved anvendelse af natriumcaprylat som et adskillelsesmiddel

Country Status (11)

Country Link
US (1) US5561115A (da)
EP (1) EP0696595B1 (da)
JP (1) JP3874029B2 (da)
KR (1) KR100418821B1 (da)
CN (1) CN1150004C (da)
AT (1) ATE172744T1 (da)
AU (1) AU684202B2 (da)
CA (1) CA2155630C (da)
DE (1) DE69505610T2 (da)
DK (1) DK0696595T3 (da)
ES (1) ES2123874T3 (da)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103236B1 (es) * 1996-01-30 1998-04-16 Grifols Grupo Sa Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.
AT403989B (de) * 1996-09-16 1998-07-27 Immuno Ag Verfahren zur herstellung eines plasmaprotein-hältigen arzneimittels
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
AUPP521298A0 (en) * 1998-08-12 1998-09-03 Life Therapeutics Limited Purification of fibrinogen
AUPP790698A0 (en) * 1998-12-23 1999-01-28 Life Therapeutics Limited Separation of microorganisms
AUPP790898A0 (en) 1998-12-23 1999-01-28 Life Therapeutics Limited Renal dialysis
US20050224355A1 (en) * 1999-12-23 2005-10-13 Brendon Conlan Removal of biological contaminants
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
AU3624400A (en) * 1999-03-19 2000-10-09 Bayer Corporation Chromatographic albumin process
US7077942B1 (en) * 1999-12-23 2006-07-18 Gradipore Limited Removal of biological contaminants
AUPQ691400A0 (en) * 2000-04-14 2000-05-11 Life Therapeutics Limited Separation of micromolecules
AUPQ697300A0 (en) 2000-04-18 2000-05-11 Life Therapeutics Limited Separation apparatus
WO2001078877A1 (en) 2000-04-18 2001-10-25 Gradipore Limited Electrophoresis separation and treatment of samples
AU7931301A (en) 2000-08-04 2002-02-18 Dmi Biosciences Inc Method of using diketopiperazines and composition containing them
US6923896B2 (en) * 2000-09-22 2005-08-02 The Texas A&M University System Electrophoresis apparatus and method
CA2422325A1 (en) * 2000-10-06 2002-04-11 Gradipore Limited Multi-port separation apparatus and method
AUPR222300A0 (en) * 2000-12-21 2001-01-25 Life Therapeutics Limited Electrophoresis device and method
US20020124526A1 (en) * 2001-03-12 2002-09-12 Lewis James D. Albumin in a flexible polymeric container
ES2575563T3 (es) 2003-05-15 2016-06-29 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
CN100376598C (zh) * 2004-01-20 2008-03-26 中国人民解放军军事医学科学院野战输血研究所 犬静脉注射白蛋白、其制备方法以及犬静脉注射白蛋白制剂
CN1314447C (zh) * 2004-04-12 2007-05-09 爱华生物科技(香港)有限公司 一种具有抑制蛋白酶作用的药物的制备方法
NZ550320A (en) * 2004-04-15 2010-02-26 Chiasma Inc Compositions capable of facilitating penetration across a biological barrier
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
CN1313488C (zh) * 2004-12-29 2007-05-02 三九集团湛江开发区双林药业有限公司 从组分沉淀123中回收白蛋白的方法
US7879332B2 (en) * 2005-09-01 2011-02-01 Plasma Technologies, Llc Ultra-high yield intravenous immune globulin preparation
US20070049732A1 (en) * 2005-09-01 2007-03-01 Zurlo Eugene J Ultra-high yield intravenous immune globulin preparation
US8293242B2 (en) * 2005-09-01 2012-10-23 Plasma Technologies, Llc Ultra-high yield of alpha-1-anti-trypsin
CA2634329A1 (en) 2005-12-22 2007-07-19 Csl Behring Gmbh Octanoate-reduced human albumin
US7735167B2 (en) * 2006-06-07 2010-06-15 Posey Company Bed enclosure
ES2294976B1 (es) 2007-11-12 2008-12-16 Grifols, S.A. "procedimiento de obtencion de albumina humana de alta eficacia para su uso en terapia de detoxificacion".
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
BRPI0918652B1 (pt) 2008-09-17 2021-10-19 Chiasma, Inc. Composição farmacêutica compreendendo um meio hidrofóbico e uma forma sólida que compreende polipeptídeo e sal de ácido graxo de cadeia média, processo de produção da mesma e forma de dosagem oral
CN101367865B (zh) * 2008-09-26 2012-01-04 广州倍绣生物技术有限公司 一种高纯度猪血白蛋白的生产工艺及其应用
CN101927011B (zh) * 2009-06-23 2014-03-19 武汉生物制品研究所有限责任公司 一种球蛋白溶液的病毒灭活方法
MX2012005132A (es) 2009-11-03 2012-07-25 Grifols Therapeutics Inc Composicion, metodo y kit para inhibidor de alfa-1 proteinasa.
US8648177B2 (en) 2009-11-24 2014-02-11 Grifols Therapeutics Inc. Lyophilization methods, compositions, and kits
CN102127164B (zh) * 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) * 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
KR20140075772A (ko) 2011-10-10 2014-06-19 앰피오 파마슈티컬스 인코퍼레이티드 면역 내성을 증가시킨 이식 의료 장비, 및 그의 제조 및 이식 방법
PL2766029T3 (pl) 2011-10-10 2020-08-24 Ampio Pharmaceuticals, Inc. Leczenie choroby zwyrodnieniowej stawów
US10881710B2 (en) 2011-10-28 2021-01-05 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
AU2013205138B2 (en) * 2012-08-09 2015-06-25 Grifols, S.A. Caprylate Viral Deactivation
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
JP6387019B2 (ja) * 2013-02-01 2018-09-05 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンおよびジケトピペラジン含有組成物を生産するための方法
KR20150132508A (ko) 2013-03-15 2015-11-25 앰피오 파마슈티컬스 인코퍼레이티드 줄기세포의 가동화, 회귀, 증식 및 분화를 위한 조성물 및 이의 사용 방법
CA2958080A1 (en) 2014-08-18 2016-02-25 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
CN104356231B (zh) * 2014-11-10 2017-08-08 北海开元生物科技有限公司 一种有效去除人免疫球蛋白多聚体的方法
CN104447987A (zh) * 2014-11-22 2015-03-25 贵州中泰生物科技有限公司 辛酸法血浆免疫球蛋白分离工艺
MA41462A (fr) 2015-02-03 2021-05-12 Chiasma Inc Méthode de traitement de maladies
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
EP3628675A1 (en) * 2015-06-26 2020-04-01 Ferring B.V. Methods of purification and/or viral inactivation
WO2017084683A1 (en) 2015-11-20 2017-05-26 Hepa Wash Gmbh Method for extracorporeal lung support
WO2017084682A1 (en) 2015-11-20 2017-05-26 Hepa Wash Gmbh Method for extracorporeal carbon dioxide removal
PL3429657T3 (pl) 2016-03-14 2022-08-22 Advitos Gmbh Systemy albo aparatury dla przeprowadzania dializy
HRP20211628T1 (hr) * 2016-08-18 2022-02-04 Alkahest, Inc. Frakcije krvne plazme kao tretman za kongitivne poremećaje povezane sa starenjem
WO2018165766A1 (en) * 2017-03-16 2018-09-20 Therapure Biopharma Inc. Method for purification of albumin
US20210100941A1 (en) * 2017-03-28 2021-04-08 Advitos Gmbh Compositions and methods for regenerating carrier protein-containing multiple pass albumin dialysis fluid
JP7213556B2 (ja) 2017-05-22 2023-01-27 アドビトス ゲーエムベーハー 二酸化炭素を除去するための方法およびシステム
CN107312082B (zh) * 2017-07-06 2020-09-01 四川新健康成生物股份有限公司 一种从血清中获取天然前白蛋白的方法
CN111195351A (zh) * 2020-01-20 2020-05-26 华兰生物工程重庆有限公司 5%低浓度人血白蛋白的制备方法
CN114605519B (zh) * 2020-12-03 2023-10-31 四川远大蜀阳药业有限责任公司 提取h因子的方法
CN112521488A (zh) * 2020-12-26 2021-03-19 郑州伊美诺生物技术有限公司 牛血清白蛋白的制备方法
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods
CN113831405B (zh) * 2021-11-17 2024-04-30 华兰生物工程重庆有限公司 一种人血白蛋白的纯化方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2710293A (en) 1953-10-30 1955-06-07 Olin Mathieson Blood fractionation
US2710294A (en) 1953-11-02 1955-06-07 Olin Mathieson Blood fractionation
FR2190437B1 (da) * 1972-07-05 1975-08-08 Merieux Inst
US3926939A (en) * 1973-08-24 1975-12-16 Mikhail Ivanovich Ivanov Method of extracting pure serum albumin from biological fluids using a salt of a carboxylic aliphatic acid
CH583745A5 (en) * 1973-09-13 1977-01-14 Ts I Gematologii I Perelivania Pure serum albumin isolated from biological liquids - by treatment with alcohol and aliphatic carboxylic acid salt
US4156681A (en) * 1974-03-28 1979-05-29 Plasmesco Ag Process for isolating albumin from blood
DK25877A (da) * 1977-01-21 1978-08-15 Nordisk Insulinlab Fremgangsmaade til udvinding af renset albumin fra blodplasma
US4222934A (en) * 1979-04-12 1980-09-16 American National Red Cross Preparation of albumin using ethanol
AT363190B (de) * 1979-05-28 1981-07-10 Oesterr Rotes Kreuz Herstellung von albumin aus plasma
US4378346A (en) * 1979-08-15 1983-03-29 Tankersley Donald L Intravenously injectable solution of plasma protein fraction free from bradykinin, kininogen and prekallikrein activators and processes for its production
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法
US4990447A (en) * 1988-06-24 1991-02-05 Gist-Brocades Nv Process for the purification of serum albumin
US4939176A (en) 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
EP0452753B1 (en) * 1990-04-19 2004-06-23 Bayer Corporation Method for preparing essentially monomeric normal serum albumin (human)

Also Published As

Publication number Publication date
DE69505610D1 (de) 1998-12-03
CA2155630A1 (en) 1996-02-11
EP0696595B1 (en) 1998-10-28
AU684202B2 (en) 1997-12-04
CN1120439A (zh) 1996-04-17
ES2123874T3 (es) 1999-01-16
ATE172744T1 (de) 1998-11-15
KR960006939A (ko) 1996-03-22
AU2839095A (en) 1996-02-22
CA2155630C (en) 2007-10-23
US5561115A (en) 1996-10-01
CN1150004C (zh) 2004-05-19
KR100418821B1 (ko) 2004-05-20
JP3874029B2 (ja) 2007-01-31
JPH08176010A (ja) 1996-07-09
EP0696595A1 (en) 1996-02-14
DE69505610T2 (de) 1999-03-25

Similar Documents

Publication Publication Date Title
DK0696595T3 (da) Albuminfraktionering ved lav temperatur ved anvendelse af natriumcaprylat som et adskillelsesmiddel
DE69807679D1 (de) Zusammensetzungen aus konjugaten des stabilen, aktiven, menschlichen ob proteins mit der fc kette von immunoglobulinen und damit zusammenhängende verfahren
CA2067653A1 (en) Modified Complement System Regulator
FI931708A0 (fi) Herbicida substituerade aryl-haloalkylpyrazoler
SE8901687D0 (sv) Fibronectin binding protein as well as its preparation
DE69534120D1 (de) Topisch anzuwendende ketoconazol enthaltende emulsionen
ATE193839T1 (de) Reinigung von proteinen
DK262585A (da) Polypeptider og salte deraf samt fremgangsmaade til fremstilling af saadanne forbindelser
ATE84216T1 (de) Topische salbe.
DK0410207T3 (da) Stabilisering af højrensede proteiner.
DK0567448T3 (da) Fremgangsmåde til fremstilling af faktor VIII
DK0925789T4 (da) Anvendelse af azithromycin ved topisk behandling af öjeninfektioner
FR2672895B1 (fr) Procede de purification d'une proteine fortement glycosylee.
SE8801723D0 (sv) Fibronectin binding protein as well as its preparation
DE69126727D1 (de) Warm-behandelte IGM-Antikörper-Zusammensetzungen
KR960701659A (ko) 정맥 주사용 글로블린 액상 조성물, 그 제조방법 및 상기 조성물중에서 글로블린 이량체의 증가를 억제시키는 방법(liquid globulin composition for intrave nous injection, process for producing the same, and method of inhibiting globulin dimer increase in said compisition)
DK0914148T3 (da) Behandling af partielt væksthormonoverfølsomhedssyndrom
KR890002388A (ko) 트롬빈 결합물질 및 그의 제조방법
KR930703420A (ko) 유출 연료의 저온성을 개선시키기 위한 다관능가 첨가제 및 그를 함유하는 조성물
ATE258012T1 (de) Mikrobizide
RU93056841A (ru) Способы лечения и защиты позвоночных от паразитов, композиции на основе дисульфонилметанов для борьбы с паразитами, новые соединения
Onji et al. Filamin inhibits actomyosin ATPase activity in platelet
DE69810724T2 (de) Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC)
FR2387240A1 (fr) Procede de preparation d'albumine humaine
SE9702993D0 (sv) Anti-mikrobial komposition