DK0663902T3 - 25-carboxylsyrederivater i vitamin D-rækken, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse ti - Google Patents

25-carboxylsyrederivater i vitamin D-rækken, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse ti

Info

Publication number
DK0663902T3
DK0663902T3 DK93922944T DK93922944T DK0663902T3 DK 0663902 T3 DK0663902 T3 DK 0663902T3 DK 93922944 T DK93922944 T DK 93922944T DK 93922944 T DK93922944 T DK 93922944T DK 0663902 T3 DK0663902 T3 DK 0663902T3
Authority
DK
Denmark
Prior art keywords
derivatives
vitamin
carboxylic acid
mean
acid derivatives
Prior art date
Application number
DK93922944T
Other languages
Danish (da)
English (en)
Inventor
Andreas Steinmeyer
Ruth Thieroff-Ekerdt
Gerald Kirsch
Guenter Neef
Katica Schwarz
Herbert Wiesinger
Martin Haberey
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4234382A external-priority patent/DE4234382A1/de
Priority claimed from DE19934317415 external-priority patent/DE4317415A1/de
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0663902T3 publication Critical patent/DK0663902T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
DK93922944T 1992-10-06 1993-10-06 25-carboxylsyrederivater i vitamin D-rækken, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse ti DK0663902T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4234382A DE4234382A1 (de) 1992-10-06 1992-10-06 25-Carbonsäure-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
DE19934317415 DE4317415A1 (de) 1993-05-18 1993-05-18 25-Carbonsäure-Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für diese Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP1993/002814 WO1994007853A1 (de) 1992-10-06 1993-10-06 25-carbonsäure-derivate in der vitamin d-reihe, verfahren zu ihrer herstellung, zwischenprodukte für diese verfahren, diese derivate enthaltende pharmazeutische präparate sowie deren verwendung zur herstellung von arzneimitteln

Publications (1)

Publication Number Publication Date
DK0663902T3 true DK0663902T3 (da) 1998-12-21

Family

ID=25919406

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93922944T DK0663902T3 (da) 1992-10-06 1993-10-06 25-carboxylsyrederivater i vitamin D-rækken, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse ti

Country Status (21)

Country Link
US (1) US5583125A (cs)
EP (1) EP0663902B1 (cs)
JP (1) JP3565847B2 (cs)
KR (1) KR100294600B1 (cs)
CN (1) CN1042026C (cs)
AT (1) ATE163923T1 (cs)
AU (1) AU671313B2 (cs)
CA (1) CA2146429C (cs)
CZ (1) CZ284926B6 (cs)
DE (1) DE59308257D1 (cs)
DK (1) DK0663902T3 (cs)
ES (1) ES2117150T3 (cs)
FI (1) FI109996B (cs)
HU (1) HU221588B (cs)
IL (1) IL107185A (cs)
MX (1) MX9306204A (cs)
NO (1) NO309599B1 (cs)
NZ (1) NZ256862A (cs)
PL (1) PL175636B1 (cs)
SK (1) SK280651B6 (cs)
WO (1) WO1994007853A1 (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
CA2166898C (en) * 1993-07-09 2004-09-07 Roger Bouillon Novel structural analogues of vitamin d
GB9315253D0 (en) * 1993-07-23 1993-09-08 Res Inst Medicine Chem Chemical compounds
CA2224440A1 (en) * 1995-06-14 1997-01-03 Schering Aktiengesellschaft New vitamin d derivatives with substituents at c-25, process for their production, intermediate products and use for the production of pharmaceutical agents
DE19549243A1 (de) * 1995-12-21 1997-06-26 Schering Ag Pharmazeutische Präparate enthaltend Clathrate von Cyclodextrinen und nichtnatürliche Vitamin D-Analoga
WO1997032998A2 (en) * 1996-03-08 1997-09-12 Isis Innovation Limited Materials and methods relating to the identification of a polymorphism associated with disease susceptibility
CA2303248A1 (en) * 1997-09-08 1999-03-18 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
DE19744127B4 (de) 1997-10-01 2006-10-05 Schering Ag Neue Vitamin D-Derivate mit Cyclopropylringen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung sowie ihre Verwendung zur Herstellung von Arzneimitteln
EP0927721A1 (de) * 1997-12-17 1999-07-07 Schering Aktiengesellschaft Neue Vitamin D-Derivate mit Phosphoratomen in den Seitenketten, Zwischenprodukte bei ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP2002508383A (ja) * 1997-12-17 2002-03-19 シエーリング アクチエンゲゼルシャフト 側鎖中にリン原子を有するビタミンｄ誘導体
AU758792B2 (en) 1998-10-23 2003-03-27 Teijin Limited Vitamin D3 derivatives and remedies for inflammatory respiratory diseases containing the same
US20030188756A1 (en) * 2002-08-19 2003-10-09 Cantorna Margherita T Treatment of inflammatory bowel disease with vitamin d compounds
JP2003516386A (ja) * 1999-12-02 2003-05-13 ザ・ペン・ステート・リサーチ・ファンデーション ビタミンｄ化合物での炎症性腸疾患の治療
US6358939B1 (en) * 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US6989377B2 (en) * 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP1342796A3 (en) * 2002-02-22 2004-01-02 Teijin Limited Compound for the treatment of paget's disease of bone
US7351869B2 (en) * 2002-11-18 2008-04-01 Teva Pharmaceutical Industries Ltd Crystallization method for purification of calcipotriene
US7704980B2 (en) * 2003-10-08 2010-04-27 Wisconsin Alumni Research Foundation Treatment of inflammatory bowel disease with 2-methylene-19-nor-vitamin D compounds
US7888339B2 (en) 2008-07-10 2011-02-15 Wisconsin Alumni Research Foundation 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs
JPWO2010053165A1 (ja) 2008-11-04 2012-04-05 帝人ファーマ株式会社 ビタミンｄ３ラクタム誘導体
JP5932339B2 (ja) 2009-01-27 2016-06-08 バーグ エルエルシー 化学療法に付随する副作用を軽減するためのビタミンｄ３およびその類似体
EA201270226A1 (ru) 2009-08-14 2012-09-28 БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи Витамин d3 и его аналогии для лечения алопеции
WO2014194133A1 (en) 2013-05-29 2014-12-04 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
US10314395B2 (en) 2017-02-21 2019-06-11 James E. McGhee, III Pallet spacer system and method of use
GB202016614D0 (en) 2020-10-20 2020-12-02 King S College London Compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022891A (en) * 1974-06-18 1977-05-10 Teijin Limited Novel 1α,24-dihydroxycholecalciferol compositions, novel precursors thereof, and processes for preparing them
JPH07100685B2 (ja) * 1985-08-02 1995-11-01 レオ・ファ−マシュ−ティカル・プロダクツ・リミテッド・エイ／エス（レ−ベンス・ケミスケ・ファブリック・プロデュクチオンスアクチ−セルスカブ） 新規ビタミンｄ類似体
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
ATE134366T1 (de) * 1991-11-07 1996-03-15 Res Inst Medicine Chem Amid derivate von vitamin d
DE4141746A1 (de) * 1991-12-13 1993-06-17 Schering Ag 20-methyl-substituierte vitamin d-derivate

Also Published As

Publication number Publication date
CZ284926B6 (cs) 1999-04-14
CA2146429C (en) 2006-12-05
JP3565847B2 (ja) 2004-09-15
IL107185A0 (en) 1994-01-25
NO309599B1 (no) 2001-02-26
US5583125A (en) 1996-12-10
KR100294600B1 (ko) 2001-09-17
AU5177193A (en) 1994-04-26
MX9306204A (es) 1994-05-31
PL308260A1 (en) 1995-07-24
NZ256862A (en) 1996-03-26
AU671313B2 (en) 1996-08-22
ES2117150T3 (es) 1998-08-01
NO951318L (no) 1995-06-02
KR950703526A (ko) 1995-09-20
HU221588B (hu) 2002-11-28
FI951614A0 (fi) 1995-04-05
EP0663902B1 (de) 1998-03-11
CN1042026C (zh) 1999-02-10
WO1994007853A1 (de) 1994-04-14
DE59308257D1 (de) 1998-04-16
SK45895A3 (en) 1995-08-09
CZ87395A3 (en) 1995-10-18
EP0663902A1 (de) 1995-07-26
FI951614L (fi) 1995-04-05
JPH08501784A (ja) 1996-02-27
ATE163923T1 (de) 1998-03-15
HU9501002D0 (en) 1995-06-28
IL107185A (en) 1998-02-22
NO951318D0 (no) 1995-04-05
PL175636B1 (pl) 1999-01-29
CN1094034A (zh) 1994-10-26
HUT70562A (en) 1995-10-30
SK280651B6 (sk) 2000-05-16
CA2146429A1 (en) 1994-04-14
FI109996B (fi) 2002-11-15

Similar Documents

Publication Publication Date Title
DK0663902T3 (da) 25-carboxylsyrederivater i vitamin D-rækken, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse ti
ES2118283T3 (es) Derivados de acidos benzofuranil- y -tiofenil-alcanocarboxilicos.
ES2071033T3 (es) Nuevos derivados de n-aril y n-heteroarilamida y urea como inhibidores de la acil coenzima a: colesterol acil transferasa.
AU529426B2 (en) 4-amino-2-ureido-pyrimidine-5-carboxylic acid anilides and their use in treating lipometabolism disturbances and adiposity
NO301542B1 (no) Nye pyrazin-derivater
AU538424B2 (en) Piperazino phenylindane
ATE13765T1 (de) 2-(1,4-benzodioxan-2-ylalkyl)-imidazole, deren herstellung und sie enthaltende pharmazeutische mittel.
YU5893A (sh) Sulfonilkarbamid i postupak za njegovo dobijanje
IL72330A (en) 3-alkyl-7-pyridyl-1h-triazolo(3,4-a)pyrimidine-5-one derivatives,their preparation and pharmaceutical compositions containing them
EP0150015A3 (en) Norbornane and norbornene carboxylic acid amides, process for their preparation and their use as medicines
NZ334119A (en) Use of pentynoic acid derivatives as neurotrophic and antiproliferative agents
ES466794A1 (es) Un procedimiento para la preparacion de derivados de imida- zol.
ATE37368T1 (de) Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES2149817T3 (es) Piridinas sustituidas, su preparacion y uso farmaceutico.
YU140491A (sh) 6-supstituisani-tetrahidrobenz(c,d) indoli
ES8200648A2 (es) Procedimiento de preparacion de compuestos opacificantes para radiografia y similares
ES2088567T3 (es) Empleo de derivados de la 2-iminotioazolidin-4-ona como nuevos productos activos para medicamentos.
ATE43575T1 (de) (4.2.0>-bicyclooctanderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
IL115085A0 (en) Bicyclic carboxamide derivatives their preparation and pharmaceutical compositions containing them
FI925618A0 (fi) Etanoladdukter av 6-sulfonylsubstituerade 3-hydroxikromaner och deras anvaendning som inhalationsmedel vid sjukdomar
ATE29251T1 (de) Aminopyridincarbonsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
NO855383L (no) Fremgangsmaate for fremstilling av piperazin-derivater.
ES456639A1 (es) Un procedimiento de preparacion de los derivados del ciclo- penta (b) tiofeno.
IT1253007B (it) Derivati dell'eserolina ad attivita' anticolinesterasica,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
ATE6514T1 (de) Clavulansaeure-derivate, ihre herstellung und pharmazeutische zubereitungen.