DK0639180T3 - Fremgangsmåde til stereospecifik hydrolyse af piperidindionderivater - Google Patents

Fremgangsmåde til stereospecifik hydrolyse af piperidindionderivater

Info

Publication number
DK0639180T3
DK0639180T3 DK93908004T DK93908004T DK0639180T3 DK 0639180 T3 DK0639180 T3 DK 0639180T3 DK 93908004 T DK93908004 T DK 93908004T DK 93908004 T DK93908004 T DK 93908004T DK 0639180 T3 DK0639180 T3 DK 0639180T3
Authority
DK
Denmark
Prior art keywords
stereospecific hydrolysis
piperidinedione derivatives
piperidinedione
derivatives
stereospecific
Prior art date
Application number
DK93908004T
Other languages
Danish (da)
English (en)
Inventor
Alan David Curzons
Lawson William Powell
Alan Martin Keay
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of DK0639180T3 publication Critical patent/DK0639180T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK93908004T 1992-05-06 1993-04-06 Fremgangsmåde til stereospecifik hydrolyse af piperidindionderivater DK0639180T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209687A GB9209687D0 (en) 1992-05-06 1992-05-06 Novel process
PCT/GB1993/000721 WO1993022284A1 (en) 1992-05-06 1993-04-06 Process for stereospecific hydrolysis of piperidinedione derivatives

Publications (1)

Publication Number Publication Date
DK0639180T3 true DK0639180T3 (da) 2000-11-06

Family

ID=10715029

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93908004T DK0639180T3 (da) 1992-05-06 1993-04-06 Fremgangsmåde til stereospecifik hydrolyse af piperidindionderivater

Country Status (33)

Country Link
US (1) US20010018205A1 (cs)
EP (1) EP0639180B1 (cs)
JP (1) JPH07507277A (cs)
KR (1) KR100287082B1 (cs)
CN (2) CN1059898C (cs)
AP (1) AP404A (cs)
AT (1) ATE194329T1 (cs)
AU (1) AU673166B2 (cs)
BR (1) BR9306326A (cs)
CA (1) CA2135169A1 (cs)
CZ (1) CZ283702B6 (cs)
DE (1) DE69328969T2 (cs)
DK (1) DK0639180T3 (cs)
ES (1) ES2147196T3 (cs)
FI (1) FI106855B (cs)
GB (1) GB9209687D0 (cs)
GR (1) GR3034034T3 (cs)
HK (1) HK1012374A1 (cs)
HU (1) HU215411B (cs)
IL (1) IL105162A (cs)
MA (1) MA22848A1 (cs)
MX (1) MX9301754A (cs)
MY (1) MY110188A (cs)
NO (1) NO944215L (cs)
NZ (1) NZ251404A (cs)
PL (1) PL172067B1 (cs)
PT (1) PT639180E (cs)
RU (1) RU2108393C1 (cs)
SI (1) SI9300158A (cs)
SK (1) SK281767B6 (cs)
TW (1) TW258732B (cs)
WO (1) WO1993022284A1 (cs)
ZA (1) ZA932212B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
EP0937152A2 (en) * 1996-07-15 1999-08-25 Smithkline Beecham Plc Screening for and use of an esterase for a stereospecific resolution
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals
CA2293247C (en) * 1997-06-10 2005-04-12 Synthon B.V. 4-phenylpiperidine compounds
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
IT1308629B1 (it) * 1999-02-23 2002-01-09 Recordati Chem Pharm Processo per la produzione di paroxetina.
ES2161167B1 (es) * 1999-09-24 2002-07-01 Vita Invest Sa Procedimiento de hidrolisis enzimatica de esteres del acido (3sr,4rs)-4-(4-fluorofenil)-6-oxopiperidin-3-carboxilico con biocatalizadores de lipasas o esterasas inmovilizadas.
WO2001085688A1 (en) 2000-05-12 2001-11-15 Synthon B.V. TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS
WO2009005647A2 (en) * 2007-06-27 2009-01-08 Bioverdant, Inc. Compounds and process to prepare chiral intermediates for synthesis of paroxetine
CN104892491B (zh) * 2015-05-06 2017-05-17 浙江海森药业有限公司 一种合成帕罗西汀手性中间体的方法
KR102168129B1 (ko) 2018-11-28 2020-10-20 장영선 넝쿨작물용 줄기 유인용 집게

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
DE3010104A1 (de) * 1980-03-15 1981-10-01 Basf Ag, 6700 Ludwigshafen Aminoazoverbindungen
DE3680184D1 (de) * 1985-08-10 1991-08-14 Beecham Group Plc Verfahren zur herstellung von arylpiperidincarbinol.
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
US5258517A (en) * 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine

Also Published As

Publication number Publication date
GR3034034T3 (en) 2000-11-30
RU2108393C1 (ru) 1998-04-10
NZ251404A (en) 1996-10-28
KR950701326A (ko) 1995-03-23
CZ271294A3 (en) 1995-07-12
ATE194329T1 (de) 2000-07-15
ES2147196T3 (es) 2000-09-01
SK281767B6 (sk) 2001-07-10
PT639180E (pt) 2000-10-31
RU94046012A (ru) 1996-09-20
HK1012374A1 (en) 1999-07-30
AP9300501A0 (en) 1993-04-30
HU215411B (hu) 2000-03-28
TW258732B (cs) 1995-10-01
BR9306326A (pt) 1998-06-30
DE69328969T2 (de) 2000-12-07
CA2135169A1 (en) 1993-11-11
CN1291653A (zh) 2001-04-18
AP404A (en) 1995-09-02
NO944215D0 (no) 1994-11-04
FI945209A0 (fi) 1994-11-04
GB9209687D0 (en) 1992-06-17
EP0639180B1 (en) 2000-07-05
IL105162A0 (en) 1993-07-08
NO944215L (no) 1994-11-04
HUT69945A (en) 1995-09-28
MX9301754A (es) 1993-11-01
IL105162A (en) 1999-01-26
MA22848A1 (fr) 1993-10-01
DE69328969D1 (de) 2000-08-10
FI945209A (fi) 1994-11-04
AU3899993A (en) 1993-11-29
EP0639180A1 (en) 1995-02-22
US20010018205A1 (en) 2001-08-30
JPH07507277A (ja) 1995-08-10
SI9300158A (sl) 1993-12-31
MY110188A (en) 1998-02-28
FI106855B (fi) 2001-04-30
PL172067B1 (pl) 1997-07-31
CN1096054A (zh) 1994-12-07
KR100287082B1 (ko) 2002-08-14
WO1993022284A1 (en) 1993-11-11
CZ283702B6 (cs) 1998-06-17
AU673166B2 (en) 1996-10-31
CN1059898C (zh) 2000-12-27
SK131594A3 (en) 1995-06-07
ZA932212B (en) 1994-09-28

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