KR100287082B1 - 피페리딘디온유도체의입체특이적가수분해방법 - Google Patents
피페리딘디온유도체의입체특이적가수분해방법 Download PDFInfo
- Publication number
- KR100287082B1 KR100287082B1 KR1019940703956A KR19940703956A KR100287082B1 KR 100287082 B1 KR100287082 B1 KR 100287082B1 KR 1019940703956 A KR1019940703956 A KR 1019940703956A KR 19940703956 A KR19940703956 A KR 19940703956A KR 100287082 B1 KR100287082 B1 KR 100287082B1
- Authority
- KR
- South Korea
- Prior art keywords
- hydrolysis method
- stereospecific hydrolysis
- piperidinedione derivatives
- piperidinedione
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929209687A GB9209687D0 (en) | 1992-05-06 | 1992-05-06 | Novel process |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950701326A KR950701326A (ko) | 1995-03-23 |
KR100287082B1 true KR100287082B1 (ko) | 2002-08-14 |
Family
ID=10715029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940703956A KR100287082B1 (ko) | 1992-05-06 | 1994-11-05 | 피페리딘디온유도체의입체특이적가수분해방법 |
Country Status (33)
Country | Link |
---|---|
US (1) | US20010018205A1 (ko) |
EP (1) | EP0639180B1 (ko) |
JP (1) | JPH07507277A (ko) |
KR (1) | KR100287082B1 (ko) |
CN (2) | CN1059898C (ko) |
AP (1) | AP404A (ko) |
AT (1) | ATE194329T1 (ko) |
AU (1) | AU673166B2 (ko) |
BR (1) | BR9306326A (ko) |
CA (1) | CA2135169A1 (ko) |
CZ (1) | CZ283702B6 (ko) |
DE (1) | DE69328969T2 (ko) |
DK (1) | DK0639180T3 (ko) |
ES (1) | ES2147196T3 (ko) |
FI (1) | FI106855B (ko) |
GB (1) | GB9209687D0 (ko) |
GR (1) | GR3034034T3 (ko) |
HK (1) | HK1012374A1 (ko) |
HU (1) | HU215411B (ko) |
IL (1) | IL105162A (ko) |
MA (1) | MA22848A1 (ko) |
MX (1) | MX9301754A (ko) |
MY (1) | MY110188A (ko) |
NO (1) | NO944215L (ko) |
NZ (1) | NZ251404A (ko) |
PL (1) | PL172067B1 (ko) |
PT (1) | PT639180E (ko) |
RU (1) | RU2108393C1 (ko) |
SI (1) | SI9300158A (ko) |
SK (1) | SK281767B6 (ko) |
TW (1) | TW258732B (ko) |
WO (1) | WO1993022284A1 (ko) |
ZA (1) | ZA932212B (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20200063576A (ko) | 2018-11-28 | 2020-06-05 | 장영선 | 넝쿨작물용 줄기 유인용 집게 |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
EP0937152A2 (en) * | 1996-07-15 | 1999-08-25 | Smithkline Beecham Plc | Screening for and use of an esterase for a stereospecific resolution |
GB9618967D0 (en) * | 1996-09-11 | 1996-10-23 | Smithkline Beecham Plc | Pharmaceuticals |
AU3108097A (en) * | 1997-06-10 | 1998-12-30 | Synthon B.V. | 4-phenylpiperidine compounds |
CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
IT1308629B1 (it) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | Processo per la produzione di paroxetina. |
ES2161167B1 (es) * | 1999-09-24 | 2002-07-01 | Vita Invest Sa | Procedimiento de hidrolisis enzimatica de esteres del acido (3sr,4rs)-4-(4-fluorofenil)-6-oxopiperidin-3-carboxilico con biocatalizadores de lipasas o esterasas inmovilizadas. |
WO2001085688A1 (en) | 2000-05-12 | 2001-11-15 | Synthon B.V. | TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS |
WO2009005647A2 (en) * | 2007-06-27 | 2009-01-08 | Bioverdant, Inc. | Compounds and process to prepare chiral intermediates for synthesis of paroxetine |
CN104892491B (zh) * | 2015-05-06 | 2017-05-17 | 浙江海森药业有限公司 | 一种合成帕罗西汀手性中间体的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
DE3010104A1 (de) * | 1980-03-15 | 1981-10-01 | Basf Ag, 6700 Ludwigshafen | Aminoazoverbindungen |
EP0223334B1 (en) * | 1985-08-10 | 1991-07-10 | Beecham Group Plc | Process for the preparation of aryl-piperidine carbinols |
ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
US5258517A (en) * | 1992-08-06 | 1993-11-02 | Sepracor, Inc. | Method of preparing optically pure precursors of paroxetine |
-
1992
- 1992-05-06 GB GB929209687A patent/GB9209687D0/en active Pending
-
1993
- 1993-03-25 AP APAP/P/1993/000501A patent/AP404A/en active
- 1993-03-25 IL IL10516293A patent/IL105162A/en not_active IP Right Cessation
- 1993-03-29 ZA ZA932212A patent/ZA932212B/xx unknown
- 1993-03-29 MX MX9301754A patent/MX9301754A/es not_active IP Right Cessation
- 1993-03-31 MY MYPI93000567A patent/MY110188A/en unknown
- 1993-03-31 MA MA23143A patent/MA22848A1/fr unknown
- 1993-03-31 SI SI9300158A patent/SI9300158A/sl unknown
- 1993-04-01 CN CN93104523A patent/CN1059898C/zh not_active Expired - Fee Related
- 1993-04-06 PT PT93908004T patent/PT639180E/pt unknown
- 1993-04-06 AU AU38999/93A patent/AU673166B2/en not_active Ceased
- 1993-04-06 BR BR9306326A patent/BR9306326A/pt not_active Application Discontinuation
- 1993-04-06 CA CA002135169A patent/CA2135169A1/en not_active Abandoned
- 1993-04-06 EP EP93908004A patent/EP0639180B1/en not_active Expired - Lifetime
- 1993-04-06 AT AT93908004T patent/ATE194329T1/de not_active IP Right Cessation
- 1993-04-06 CZ CZ942712A patent/CZ283702B6/cs not_active IP Right Cessation
- 1993-04-06 HU HU9403189A patent/HU215411B/hu not_active IP Right Cessation
- 1993-04-06 WO PCT/GB1993/000721 patent/WO1993022284A1/en active IP Right Grant
- 1993-04-06 NZ NZ251404A patent/NZ251404A/en unknown
- 1993-04-06 JP JP5519022A patent/JPH07507277A/ja active Pending
- 1993-04-06 RU RU94046012A patent/RU2108393C1/ru active
- 1993-04-06 SK SK1315-94A patent/SK281767B6/sk unknown
- 1993-04-06 ES ES93908004T patent/ES2147196T3/es not_active Expired - Lifetime
- 1993-04-06 DE DE69328969T patent/DE69328969T2/de not_active Expired - Fee Related
- 1993-04-06 DK DK93908004T patent/DK0639180T3/da active
- 1993-04-06 PL PL93305801A patent/PL172067B1/pl unknown
- 1993-04-14 TW TW082102827A patent/TW258732B/zh active
-
1994
- 1994-11-04 NO NO944215A patent/NO944215L/no not_active Application Discontinuation
- 1994-11-04 FI FI945209A patent/FI106855B/fi active
- 1994-11-05 KR KR1019940703956A patent/KR100287082B1/ko not_active IP Right Cessation
-
1998
- 1998-12-16 HK HK98113575A patent/HK1012374A1/xx not_active IP Right Cessation
-
2000
- 2000-04-03 CN CN00104973A patent/CN1291653A/zh active Pending
- 2000-07-27 GR GR20000401724T patent/GR3034034T3/el not_active IP Right Cessation
-
2001
- 2001-03-21 US US09/813,755 patent/US20010018205A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20200063576A (ko) | 2018-11-28 | 2020-06-05 | 장영선 | 넝쿨작물용 줄기 유인용 집게 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |