KR100287082B1 - 피페리딘디온유도체의입체특이적가수분해방법 - Google Patents

피페리딘디온유도체의입체특이적가수분해방법 Download PDF

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Publication number
KR100287082B1
KR100287082B1 KR1019940703956A KR19940703956A KR100287082B1 KR 100287082 B1 KR100287082 B1 KR 100287082B1 KR 1019940703956 A KR1019940703956 A KR 1019940703956A KR 19940703956 A KR19940703956 A KR 19940703956A KR 100287082 B1 KR100287082 B1 KR 100287082B1
Authority
KR
South Korea
Prior art keywords
hydrolysis method
stereospecific hydrolysis
piperidinedione derivatives
piperidinedione
derivatives
Prior art date
Application number
KR1019940703956A
Other languages
English (en)
Other versions
KR950701326A (ko
Inventor
알란데이빗컬존스
로손윌리암포웰
알란마아틴키이
Original Assignee
스미스클라인비이참피이엘시이
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스미스클라인비이참피이엘시이 filed Critical 스미스클라인비이참피이엘시이
Publication of KR950701326A publication Critical patent/KR950701326A/ko
Application granted granted Critical
Publication of KR100287082B1 publication Critical patent/KR100287082B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
KR1019940703956A 1992-05-06 1994-11-05 피페리딘디온유도체의입체특이적가수분해방법 KR100287082B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929209687A GB9209687D0 (en) 1992-05-06 1992-05-06 Novel process

Publications (2)

Publication Number Publication Date
KR950701326A KR950701326A (ko) 1995-03-23
KR100287082B1 true KR100287082B1 (ko) 2002-08-14

Family

ID=10715029

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940703956A KR100287082B1 (ko) 1992-05-06 1994-11-05 피페리딘디온유도체의입체특이적가수분해방법

Country Status (33)

Country Link
US (1) US20010018205A1 (ko)
EP (1) EP0639180B1 (ko)
JP (1) JPH07507277A (ko)
KR (1) KR100287082B1 (ko)
CN (2) CN1059898C (ko)
AP (1) AP404A (ko)
AT (1) ATE194329T1 (ko)
AU (1) AU673166B2 (ko)
BR (1) BR9306326A (ko)
CA (1) CA2135169A1 (ko)
CZ (1) CZ283702B6 (ko)
DE (1) DE69328969T2 (ko)
DK (1) DK0639180T3 (ko)
ES (1) ES2147196T3 (ko)
FI (1) FI106855B (ko)
GB (1) GB9209687D0 (ko)
GR (1) GR3034034T3 (ko)
HK (1) HK1012374A1 (ko)
HU (1) HU215411B (ko)
IL (1) IL105162A (ko)
MA (1) MA22848A1 (ko)
MX (1) MX9301754A (ko)
MY (1) MY110188A (ko)
NO (1) NO944215L (ko)
NZ (1) NZ251404A (ko)
PL (1) PL172067B1 (ko)
PT (1) PT639180E (ko)
RU (1) RU2108393C1 (ko)
SI (1) SI9300158A (ko)
SK (1) SK281767B6 (ko)
TW (1) TW258732B (ko)
WO (1) WO1993022284A1 (ko)
ZA (1) ZA932212B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200063576A (ko) 2018-11-28 2020-06-05 장영선 넝쿨작물용 줄기 유인용 집게

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
EP0937152A2 (en) * 1996-07-15 1999-08-25 Smithkline Beecham Plc Screening for and use of an esterase for a stereospecific resolution
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals
CA2293247C (en) * 1997-06-10 2005-04-12 Synthon B.V. 4-phenylpiperidine compounds
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
IT1308629B1 (it) * 1999-02-23 2002-01-09 Recordati Chem Pharm Processo per la produzione di paroxetina.
ES2161167B1 (es) * 1999-09-24 2002-07-01 Vita Invest Sa Procedimiento de hidrolisis enzimatica de esteres del acido (3sr,4rs)-4-(4-fluorofenil)-6-oxopiperidin-3-carboxilico con biocatalizadores de lipasas o esterasas inmovilizadas.
WO2001085688A1 (en) 2000-05-12 2001-11-15 Synthon B.V. TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS
WO2009005647A2 (en) * 2007-06-27 2009-01-08 Bioverdant, Inc. Compounds and process to prepare chiral intermediates for synthesis of paroxetine
CN104892491B (zh) * 2015-05-06 2017-05-17 浙江海森药业有限公司 一种合成帕罗西汀手性中间体的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
DE3010104A1 (de) * 1980-03-15 1981-10-01 Basf Ag, 6700 Ludwigshafen Aminoazoverbindungen
DE3680184D1 (de) * 1985-08-10 1991-08-14 Beecham Group Plc Verfahren zur herstellung von arylpiperidincarbinol.
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
US5258517A (en) * 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200063576A (ko) 2018-11-28 2020-06-05 장영선 넝쿨작물용 줄기 유인용 집게

Also Published As

Publication number Publication date
GR3034034T3 (en) 2000-11-30
RU2108393C1 (ru) 1998-04-10
NZ251404A (en) 1996-10-28
KR950701326A (ko) 1995-03-23
CZ271294A3 (en) 1995-07-12
ATE194329T1 (de) 2000-07-15
ES2147196T3 (es) 2000-09-01
SK281767B6 (sk) 2001-07-10
PT639180E (pt) 2000-10-31
RU94046012A (ru) 1996-09-20
HK1012374A1 (en) 1999-07-30
AP9300501A0 (en) 1993-04-30
HU215411B (hu) 2000-03-28
TW258732B (ko) 1995-10-01
BR9306326A (pt) 1998-06-30
DE69328969T2 (de) 2000-12-07
CA2135169A1 (en) 1993-11-11
CN1291653A (zh) 2001-04-18
AP404A (en) 1995-09-02
NO944215D0 (no) 1994-11-04
FI945209A0 (fi) 1994-11-04
GB9209687D0 (en) 1992-06-17
EP0639180B1 (en) 2000-07-05
IL105162A0 (en) 1993-07-08
NO944215L (no) 1994-11-04
HUT69945A (en) 1995-09-28
MX9301754A (es) 1993-11-01
IL105162A (en) 1999-01-26
MA22848A1 (fr) 1993-10-01
DK0639180T3 (da) 2000-11-06
DE69328969D1 (de) 2000-08-10
FI945209A (fi) 1994-11-04
AU3899993A (en) 1993-11-29
EP0639180A1 (en) 1995-02-22
US20010018205A1 (en) 2001-08-30
JPH07507277A (ja) 1995-08-10
SI9300158A (sl) 1993-12-31
MY110188A (en) 1998-02-28
FI106855B (fi) 2001-04-30
PL172067B1 (pl) 1997-07-31
CN1096054A (zh) 1994-12-07
WO1993022284A1 (en) 1993-11-11
CZ283702B6 (cs) 1998-06-17
AU673166B2 (en) 1996-10-31
CN1059898C (zh) 2000-12-27
SK131594A3 (en) 1995-06-07
ZA932212B (en) 1994-09-28

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A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee