ATE194329T1 - Verfahren zur stereospezifischen hydrolyse von piperidin-dion derivaten - Google Patents
Verfahren zur stereospezifischen hydrolyse von piperidin-dion derivatenInfo
- Publication number
- ATE194329T1 ATE194329T1 AT93908004T AT93908004T ATE194329T1 AT E194329 T1 ATE194329 T1 AT E194329T1 AT 93908004 T AT93908004 T AT 93908004T AT 93908004 T AT93908004 T AT 93908004T AT E194329 T1 ATE194329 T1 AT E194329T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidine
- dione derivatives
- stereospecific hydrolysis
- stereospecific
- hydrolysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929209687A GB9209687D0 (en) | 1992-05-06 | 1992-05-06 | Novel process |
| PCT/GB1993/000721 WO1993022284A1 (en) | 1992-05-06 | 1993-04-06 | Process for stereospecific hydrolysis of piperidinedione derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE194329T1 true ATE194329T1 (de) | 2000-07-15 |
Family
ID=10715029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93908004T ATE194329T1 (de) | 1992-05-06 | 1993-04-06 | Verfahren zur stereospezifischen hydrolyse von piperidin-dion derivaten |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US20010018205A1 (de) |
| EP (1) | EP0639180B1 (de) |
| JP (1) | JPH07507277A (de) |
| KR (1) | KR100287082B1 (de) |
| CN (2) | CN1059898C (de) |
| AP (1) | AP404A (de) |
| AT (1) | ATE194329T1 (de) |
| AU (1) | AU673166B2 (de) |
| BR (1) | BR9306326A (de) |
| CA (1) | CA2135169A1 (de) |
| CZ (1) | CZ283702B6 (de) |
| DE (1) | DE69328969T2 (de) |
| DK (1) | DK0639180T3 (de) |
| ES (1) | ES2147196T3 (de) |
| FI (1) | FI106855B (de) |
| GB (1) | GB9209687D0 (de) |
| GR (1) | GR3034034T3 (de) |
| HK (1) | HK1012374A1 (de) |
| HU (1) | HU215411B (de) |
| IL (1) | IL105162A (de) |
| MA (1) | MA22848A1 (de) |
| MX (1) | MX9301754A (de) |
| MY (1) | MY110188A (de) |
| NO (1) | NO944215D0 (de) |
| NZ (1) | NZ251404A (de) |
| PL (1) | PL172067B1 (de) |
| PT (1) | PT639180E (de) |
| RU (1) | RU2108393C1 (de) |
| SI (1) | SI9300158A (de) |
| SK (1) | SK281767B6 (de) |
| TW (1) | TW258732B (de) |
| WO (1) | WO1993022284A1 (de) |
| ZA (1) | ZA932212B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
| JP2000514653A (ja) * | 1996-07-15 | 2000-11-07 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 立体特異的分割のためのエステラーゼのスクリーニングおよびその使用 |
| GB9618967D0 (en) * | 1996-09-11 | 1996-10-23 | Smithkline Beecham Plc | Pharmaceuticals |
| ES2155995T3 (es) | 1997-06-10 | 2001-06-01 | Synthon Bv | Compuestos de 4-fenilpiperidina. |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| IT1308629B1 (it) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | Processo per la produzione di paroxetina. |
| ES2161167B1 (es) * | 1999-09-24 | 2002-07-01 | Vita Invest Sa | Procedimiento de hidrolisis enzimatica de esteres del acido (3sr,4rs)-4-(4-fluorofenil)-6-oxopiperidin-3-carboxilico con biocatalizadores de lipasas o esterasas inmovilizadas. |
| WO2001085688A1 (en) | 2000-05-12 | 2001-11-15 | Synthon B.V. | TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS |
| WO2009005647A2 (en) * | 2007-06-27 | 2009-01-08 | Bioverdant, Inc. | Compounds and process to prepare chiral intermediates for synthesis of paroxetine |
| CN104892491B (zh) * | 2015-05-06 | 2017-05-17 | 浙江海森药业有限公司 | 一种合成帕罗西汀手性中间体的方法 |
| KR102168129B1 (ko) | 2018-11-28 | 2020-10-20 | 장영선 | 넝쿨작물용 줄기 유인용 집게 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| DE3010104A1 (de) * | 1980-03-15 | 1981-10-01 | Basf Ag, 6700 Ludwigshafen | Aminoazoverbindungen |
| EP0223334B1 (de) * | 1985-08-10 | 1991-07-10 | Beecham Group Plc | Verfahren zur Herstellung von Arylpiperidincarbinol |
| DE3688827T2 (de) * | 1985-10-25 | 1994-03-31 | Beecham Group Plc | Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel. |
| DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
| US5258517A (en) * | 1992-08-06 | 1993-11-02 | Sepracor, Inc. | Method of preparing optically pure precursors of paroxetine |
-
1992
- 1992-05-06 GB GB929209687A patent/GB9209687D0/en active Pending
-
1993
- 1993-03-25 AP APAP/P/1993/000501A patent/AP404A/en active
- 1993-03-25 IL IL10516293A patent/IL105162A/en not_active IP Right Cessation
- 1993-03-29 MX MX9301754A patent/MX9301754A/es not_active IP Right Cessation
- 1993-03-29 ZA ZA932212A patent/ZA932212B/xx unknown
- 1993-03-31 MA MA23143A patent/MA22848A1/fr unknown
- 1993-03-31 MY MYPI93000567A patent/MY110188A/en unknown
- 1993-03-31 SI SI9300158A patent/SI9300158A/sl unknown
- 1993-04-01 CN CN93104523A patent/CN1059898C/zh not_active Expired - Fee Related
- 1993-04-06 AU AU38999/93A patent/AU673166B2/en not_active Ceased
- 1993-04-06 AT AT93908004T patent/ATE194329T1/de not_active IP Right Cessation
- 1993-04-06 CA CA002135169A patent/CA2135169A1/en not_active Abandoned
- 1993-04-06 PL PL93305801A patent/PL172067B1/pl unknown
- 1993-04-06 PT PT93908004T patent/PT639180E/pt unknown
- 1993-04-06 DE DE69328969T patent/DE69328969T2/de not_active Expired - Fee Related
- 1993-04-06 EP EP93908004A patent/EP0639180B1/de not_active Expired - Lifetime
- 1993-04-06 ES ES93908004T patent/ES2147196T3/es not_active Expired - Lifetime
- 1993-04-06 NZ NZ251404A patent/NZ251404A/en unknown
- 1993-04-06 HU HU9403189A patent/HU215411B/hu not_active IP Right Cessation
- 1993-04-06 RU RU94046012A patent/RU2108393C1/ru active
- 1993-04-06 WO PCT/GB1993/000721 patent/WO1993022284A1/en active IP Right Grant
- 1993-04-06 CZ CZ942712A patent/CZ283702B6/cs not_active IP Right Cessation
- 1993-04-06 DK DK93908004T patent/DK0639180T3/da active
- 1993-04-06 JP JP5519022A patent/JPH07507277A/ja active Pending
- 1993-04-06 BR BR9306326A patent/BR9306326A/pt not_active Application Discontinuation
- 1993-04-06 SK SK1315-94A patent/SK281767B6/sk unknown
- 1993-04-14 TW TW082102827A patent/TW258732B/zh active
-
1994
- 1994-11-04 NO NO944215A patent/NO944215D0/no not_active Application Discontinuation
- 1994-11-04 FI FI945209A patent/FI106855B/fi active
- 1994-11-05 KR KR1019940703956A patent/KR100287082B1/ko not_active IP Right Cessation
-
1998
- 1998-12-16 HK HK98113575A patent/HK1012374A1/xx not_active IP Right Cessation
-
2000
- 2000-04-03 CN CN00104973A patent/CN1291653A/zh active Pending
- 2000-07-27 GR GR20000401724T patent/GR3034034T3/el not_active IP Right Cessation
-
2001
- 2001-03-21 US US09/813,755 patent/US20010018205A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |