HK1012374A1 - Process for stereospecific hydrolysis of piperidinedione derivatives - Google Patents

Process for stereospecific hydrolysis of piperidinedione derivatives

Info

Publication number
HK1012374A1
HK1012374A1 HK98113575A HK98113575A HK1012374A1 HK 1012374 A1 HK1012374 A1 HK 1012374A1 HK 98113575 A HK98113575 A HK 98113575A HK 98113575 A HK98113575 A HK 98113575A HK 1012374 A1 HK1012374 A1 HK 1012374A1
Authority
HK
Hong Kong
Prior art keywords
stereospecific hydrolysis
piperidinedione derivatives
piperidinedione
derivatives
stereospecific
Prior art date
Application number
HK98113575A
Other languages
English (en)
Inventor
Alan David Curzons
Lawson William Powell
Alan Martin Keay
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HK1012374A1 publication Critical patent/HK1012374A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
HK98113575A 1992-05-06 1998-12-16 Process for stereospecific hydrolysis of piperidinedione derivatives HK1012374A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209687A GB9209687D0 (en) 1992-05-06 1992-05-06 Novel process
PCT/GB1993/000721 WO1993022284A1 (en) 1992-05-06 1993-04-06 Process for stereospecific hydrolysis of piperidinedione derivatives

Publications (1)

Publication Number Publication Date
HK1012374A1 true HK1012374A1 (en) 1999-07-30

Family

ID=10715029

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113575A HK1012374A1 (en) 1992-05-06 1998-12-16 Process for stereospecific hydrolysis of piperidinedione derivatives

Country Status (33)

Country Link
US (1) US20010018205A1 (de)
EP (1) EP0639180B1 (de)
JP (1) JPH07507277A (de)
KR (1) KR100287082B1 (de)
CN (2) CN1059898C (de)
AP (1) AP404A (de)
AT (1) ATE194329T1 (de)
AU (1) AU673166B2 (de)
BR (1) BR9306326A (de)
CA (1) CA2135169A1 (de)
CZ (1) CZ283702B6 (de)
DE (1) DE69328969T2 (de)
DK (1) DK0639180T3 (de)
ES (1) ES2147196T3 (de)
FI (1) FI106855B (de)
GB (1) GB9209687D0 (de)
GR (1) GR3034034T3 (de)
HK (1) HK1012374A1 (de)
HU (1) HU215411B (de)
IL (1) IL105162A (de)
MA (1) MA22848A1 (de)
MX (1) MX9301754A (de)
MY (1) MY110188A (de)
NO (1) NO944215D0 (de)
NZ (1) NZ251404A (de)
PL (1) PL172067B1 (de)
PT (1) PT639180E (de)
RU (1) RU2108393C1 (de)
SI (1) SI9300158A (de)
SK (1) SK281767B6 (de)
TW (1) TW258732B (de)
WO (1) WO1993022284A1 (de)
ZA (1) ZA932212B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
JP2000514653A (ja) * 1996-07-15 2000-11-07 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 立体特異的分割のためのエステラーゼのスクリーニングおよびその使用
GB9618967D0 (en) * 1996-09-11 1996-10-23 Smithkline Beecham Plc Pharmaceuticals
ES2155995T3 (es) 1997-06-10 2001-06-01 Synthon Bv Compuestos de 4-fenilpiperidina.
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
IT1308629B1 (it) * 1999-02-23 2002-01-09 Recordati Chem Pharm Processo per la produzione di paroxetina.
ES2161167B1 (es) * 1999-09-24 2002-07-01 Vita Invest Sa Procedimiento de hidrolisis enzimatica de esteres del acido (3sr,4rs)-4-(4-fluorofenil)-6-oxopiperidin-3-carboxilico con biocatalizadores de lipasas o esterasas inmovilizadas.
WO2001085688A1 (en) 2000-05-12 2001-11-15 Synthon B.V. TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS
WO2009005647A2 (en) * 2007-06-27 2009-01-08 Bioverdant, Inc. Compounds and process to prepare chiral intermediates for synthesis of paroxetine
CN104892491B (zh) * 2015-05-06 2017-05-17 浙江海森药业有限公司 一种合成帕罗西汀手性中间体的方法
KR102168129B1 (ko) 2018-11-28 2020-10-20 장영선 넝쿨작물용 줄기 유인용 집게

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
DE3010104A1 (de) * 1980-03-15 1981-10-01 Basf Ag, 6700 Ludwigshafen Aminoazoverbindungen
EP0223334B1 (de) * 1985-08-10 1991-07-10 Beecham Group Plc Verfahren zur Herstellung von Arylpiperidincarbinol
DE3688827T2 (de) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
US5258517A (en) * 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine

Also Published As

Publication number Publication date
JPH07507277A (ja) 1995-08-10
CN1291653A (zh) 2001-04-18
FI945209A0 (fi) 1994-11-04
SI9300158A (sl) 1993-12-31
ES2147196T3 (es) 2000-09-01
FI945209A (fi) 1994-11-04
AU673166B2 (en) 1996-10-31
CN1059898C (zh) 2000-12-27
PL172067B1 (pl) 1997-07-31
HUT69945A (en) 1995-09-28
EP0639180A1 (de) 1995-02-22
NO944215L (no) 1994-11-04
RU2108393C1 (ru) 1998-04-10
DK0639180T3 (da) 2000-11-06
SK281767B6 (sk) 2001-07-10
MA22848A1 (fr) 1993-10-01
US20010018205A1 (en) 2001-08-30
RU94046012A (ru) 1996-09-20
CZ283702B6 (cs) 1998-06-17
AP404A (en) 1995-09-02
GB9209687D0 (en) 1992-06-17
CA2135169A1 (en) 1993-11-11
AP9300501A0 (en) 1993-04-30
PT639180E (pt) 2000-10-31
IL105162A0 (en) 1993-07-08
HU215411B (hu) 2000-03-28
CN1096054A (zh) 1994-12-07
NO944215D0 (no) 1994-11-04
WO1993022284A1 (en) 1993-11-11
AU3899993A (en) 1993-11-29
GR3034034T3 (en) 2000-11-30
BR9306326A (pt) 1998-06-30
SK131594A3 (en) 1995-06-07
ZA932212B (en) 1994-09-28
MX9301754A (es) 1993-11-01
KR100287082B1 (ko) 2002-08-14
FI106855B (fi) 2001-04-30
DE69328969T2 (de) 2000-12-07
DE69328969D1 (de) 2000-08-10
KR950701326A (ko) 1995-03-23
ATE194329T1 (de) 2000-07-15
EP0639180B1 (de) 2000-07-05
IL105162A (en) 1999-01-26
NZ251404A (en) 1996-10-28
MY110188A (en) 1998-02-28
CZ271294A3 (en) 1995-07-12
TW258732B (de) 1995-10-01

Similar Documents

Publication Publication Date Title
HU9302734D0 (en) Process for producing substituted pyrimidine derivatives
HU911789D0 (en) Process for producing derivatives of triazolo-triazine and pyrazolo-triazine
IL105328A0 (en) Process for preparing piperidine derivatives
HK1012374A1 (en) Process for stereospecific hydrolysis of piperidinedione derivatives
ZA932439B (en) Process for the preparation of cinnamic acid derivatives
HU9201412D0 (en) Process for the enzymatic hydrolysis of carbonic acid derivatives
HUT40443A (en) Process for producing 6-/trisubstituted methyl/-penicillanic acid and derivatives
HUT65954A (en) Process for producing of salts of deteroxamin b
HU9401830D0 (en) Process for producing intermediates of pyranyl-cyanoguanidine derivatives
HUT48890A (en) Process for producing cephalosporin derivative
HUT50146A (en) Process for production of derivatives of lactole
HU9303551D0 (en) Process for producing phenylacetic acid derivatives
HU912328D0 (en) Process for producing d-histidine and its derivatives of 1-histidine
HU9401981D0 (en) Process for preparation of chloro-methyl-pyridin derivatives
EP0485952A3 (en) Process for production of 3-amino-4-methylenepyrrolidine derivatives
EP0585678A3 (en) Process of preparing reduction products of 4-hydroxybutyric acid derivatives
HU9201341D0 (en) Process for the production of 4'-demethyl-epipodophyllotoxin-glycosid-4'-phosphate derivatives
HUT50192A (en) Process for production of derivatives of homonojirimicine
HUT65378A (en) Process for proceeding of carbazolon derivatives
HUT63386A (en) Process for producing substituted 2-cyanopyridine derivatives
HUT68407A (en) Process for production of eicosapentaeonic acid
HUT65360A (en) Process for preparation of n-cyano-guanidine derivatives
YU44789B (en) Process for producing derivatives of trihaloimidazole
HU9202534D0 (en) Method for producing 10-acylated apovincaminic acid derivatives
HU9203587D0 (en) Method for making solutions of high purity

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20040406

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)