ITTO930336A0 - Procedimento per la produzione dell4estere metilico di alfa-l-aspartil - l-fenilalanina - Google Patents
Procedimento per la produzione dell4estere metilico di alfa-l-aspartil - l-fenilalaninaInfo
- Publication number
- ITTO930336A0 ITTO930336A0 IT93TO336A ITTO930336A ITTO930336A0 IT TO930336 A0 ITTO930336 A0 IT TO930336A0 IT 93TO336 A IT93TO336 A IT 93TO336A IT TO930336 A ITTO930336 A IT TO930336A IT TO930336 A0 ITTO930336 A0 IT TO930336A0
- Authority
- IT
- Italy
- Prior art keywords
- aspartyl
- alpha
- production
- methyl ester
- phenylalanine methyl
- Prior art date
Links
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93596192A | 1992-08-27 | 1992-08-27 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITTO930336A0 true ITTO930336A0 (it) | 1993-05-14 |
| ITTO930336A1 ITTO930336A1 (it) | 1994-11-14 |
| IT1270852B IT1270852B (it) | 1997-05-13 |
Family
ID=25467976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITTO930336A IT1270852B (it) | 1992-08-27 | 1993-05-14 | Procedimento per la produzione dell'estere metilico di alfa-l-aspartil-l-fenilalanina. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5334746A (it) |
| KR (1) | KR970009594B1 (it) |
| CH (1) | CH687825A5 (it) |
| DE (1) | DE4328967A1 (it) |
| FR (1) | FR2695128B1 (it) |
| GB (1) | GB2270311B (it) |
| IT (1) | IT1270852B (it) |
| NL (1) | NL9301303A (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010096940A (ko) * | 2000-04-19 | 2001-11-08 | 고두모 | 알파-엘-아스파틸-엘-페닐알라닌 메틸에스테르 염산염의제조방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3492131A (en) * | 1966-04-18 | 1970-01-27 | Searle & Co | Peptide sweetening agents |
| US3786039A (en) * | 1969-04-30 | 1974-01-15 | Ajinomoto Kk | Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters |
| US3933781A (en) * | 1973-11-05 | 1976-01-20 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters |
| JPS5223001A (en) * | 1975-08-14 | 1977-02-21 | Ajinomoto Co Inc | Process for elimination of formyl group |
| JPS58185545A (ja) * | 1982-04-22 | 1983-10-29 | Ajinomoto Co Inc | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法 |
| US4680403A (en) * | 1985-01-17 | 1987-07-14 | Ajinomoto Co., Inc. | Process for producing N-protected-α-L-aspartyl-L-phenylalanine methyl ester |
| DE3600731A1 (de) * | 1986-01-13 | 1987-07-16 | Green Cross Korea | Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester |
| JPH0657719B2 (ja) * | 1986-06-03 | 1994-08-03 | 味の素株式会社 | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法 |
| KR910007940B1 (ko) * | 1989-04-14 | 1991-10-04 | 주식회사 미원 | L-페닐알라닌 메틸에스테르 염산염의 정석법 |
-
1993
- 1993-05-14 IT ITTO930336A patent/IT1270852B/it active IP Right Grant
- 1993-05-28 FR FR9306439A patent/FR2695128B1/fr not_active Expired - Fee Related
- 1993-07-23 NL NL9301303A patent/NL9301303A/nl active Search and Examination
- 1993-08-13 CH CH02407/93A patent/CH687825A5/de not_active IP Right Cessation
- 1993-08-17 GB GB9317124A patent/GB2270311B/en not_active Expired - Fee Related
- 1993-08-26 KR KR93016693A patent/KR970009594B1/ko not_active IP Right Cessation
- 1993-08-27 DE DE4328967A patent/DE4328967A1/de not_active Withdrawn
- 1993-12-06 US US08/161,437 patent/US5334746A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR970009594B1 (en) | 1997-06-14 |
| GB2270311A (en) | 1994-03-09 |
| NL9301303A (nl) | 1994-03-16 |
| IT1270852B (it) | 1997-05-13 |
| CH687825A5 (de) | 1997-02-28 |
| ITTO930336A1 (it) | 1994-11-14 |
| GB9317124D0 (en) | 1993-09-29 |
| GB2270311B (en) | 1996-10-02 |
| DE4328967A1 (de) | 1994-03-03 |
| KR940003905A (ko) | 1994-03-14 |
| FR2695128A1 (fr) | 1994-03-04 |
| FR2695128B1 (fr) | 1995-07-07 |
| US5334746A (en) | 1994-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970813 |