KR970009594B1 - PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER - Google Patents

PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER Download PDF

Info

Publication number
KR970009594B1
KR970009594B1 KR93016693A KR930016693A KR970009594B1 KR 970009594 B1 KR970009594 B1 KR 970009594B1 KR 93016693 A KR93016693 A KR 93016693A KR 930016693 A KR930016693 A KR 930016693A KR 970009594 B1 KR970009594 B1 KR 970009594B1
Authority
KR
South Korea
Prior art keywords
produced
methyl ester
strong acidic
phenylalanine methyl
aspartyl
Prior art date
Application number
KR93016693A
Other languages
English (en)
Other versions
KR940003905A (ko
Inventor
Kyung-Suk Choe
Dae-Kwon Joo
Min-Soo Han
Ee-Nam Hwang
Hong-Kyu Choe
Original Assignee
Miwon Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miwon Co Ltd filed Critical Miwon Co Ltd
Publication of KR940003905A publication Critical patent/KR940003905A/ko
Priority to KR97009502A priority Critical patent/KR970009595B1/ko
Application granted granted Critical
Publication of KR970009594B1 publication Critical patent/KR970009594B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR93016693A 1992-08-27 1993-08-26 PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER KR970009594B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR97009502A KR970009595B1 (en) 1992-08-27 1997-03-20 PROCESS FOR PRODUCING Ñß-L-ASPARTYL-L- PHENYLALANINE METHLY ESTER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93596192A 1992-08-27 1992-08-27
JP7/935,961 1992-08-27

Publications (2)

Publication Number Publication Date
KR940003905A KR940003905A (ko) 1994-03-14
KR970009594B1 true KR970009594B1 (en) 1997-06-14

Family

ID=25467976

Family Applications (1)

Application Number Title Priority Date Filing Date
KR93016693A KR970009594B1 (en) 1992-08-27 1993-08-26 PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER

Country Status (8)

Country Link
US (1) US5334746A (ko)
KR (1) KR970009594B1 (ko)
CH (1) CH687825A5 (ko)
DE (1) DE4328967A1 (ko)
FR (1) FR2695128B1 (ko)
GB (1) GB2270311B (ko)
IT (1) IT1270852B (ko)
NL (1) NL9301303A (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010096940A (ko) * 2000-04-19 2001-11-08 고두모 알파-엘-아스파틸-엘-페닐알라닌 메틸에스테르 염산염의제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3786039A (en) * 1969-04-30 1974-01-15 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
US4680403A (en) * 1985-01-17 1987-07-14 Ajinomoto Co., Inc. Process for producing N-protected-α-L-aspartyl-L-phenylalanine methyl ester
DE3600731A1 (de) * 1986-01-13 1987-07-16 Green Cross Korea Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
JPH0657719B2 (ja) * 1986-06-03 1994-08-03 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法
KR910007940B1 (ko) * 1989-04-14 1991-10-04 주식회사 미원 L-페닐알라닌 메틸에스테르 염산염의 정석법

Also Published As

Publication number Publication date
US5334746A (en) 1994-08-02
DE4328967A1 (de) 1994-03-03
IT1270852B (it) 1997-05-13
FR2695128B1 (fr) 1995-07-07
NL9301303A (nl) 1994-03-16
FR2695128A1 (fr) 1994-03-04
ITTO930336A1 (it) 1994-11-14
CH687825A5 (de) 1997-02-28
GB9317124D0 (en) 1993-09-29
GB2270311A (en) 1994-03-09
GB2270311B (en) 1996-10-02
KR940003905A (ko) 1994-03-14
ITTO930336A0 (it) 1993-05-14

Similar Documents

Publication Publication Date Title
WO1996030010A3 (fr) Utilisation du fumagillol et ses derives pour preparer les medicaments destines a combattre les infections intestinales
ES8606356A1 (es) Procedimiento para preparar noroximorfona a partir de morfi-na
CA2040925A1 (en) Method of purifying polyunsaturated aliphatic compounds
IE821911L (en) Preparing insulin derivatives
KR970009594B1 (en) PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER
AU598565B2 (en) Process for producing alpha-l-aspartyl-l-phenylalanine methyl ester having an improved solubility
NZ333574A (en) Water miscible erythromycin solutions
FR2736549B1 (fr) Esters d'acides gras iodes, acides gras iodes et leurs derives, obtenus par iodohydrination faisant intervenir des derives alkylsilyles avec des iodures alcalins et leurs activites pharmacologiques
SE9101431L (sv) Foerfarande foer framstaellning av furo-(3,4-c)-pyriinderivat i ickeracemisk form
EP0402322A3 (en) Process for the production of r(+)-aminocarnitine and s(-)-amino-carnitine
DK0482344T3 (da) Fremgangsmåde til fremstilling af uforsæbelige forbindelser
Kurasawa et al. The structure of MS-3: A glyoxalase I inhibitor produced by a mushroom
EP0240431A3 (en) Process for the preparation of ethylenic carbonyl compounds
JPS5395958A (en) Prostaglandin analogues and process for their preparation
AU7681987A (en) Process for producing alpha-L-aspartyl-L-phenylalanine methyl ester having an improved solubility
KR860008117A (ko) 비닐사이클로프로판 카복실산 에스테르의 제조방법
JPS55122758A (en) Racemization of l-alpha-methyl-beta-acylthiopropionic acid
EP0330444A3 (en) Novel thiorhodamines and a novel method of preparation
DE69427148T2 (de) Verfahren zur Herstellung von 2,4,5-Tribrompyrrol-3-carbonitril
OA06793A (fr) Procédé de préparation de dérivés esters d'acides cyclopropane-carboxyliques.
JPS5227715A (en) Process for preparation of gamma-halogeno-delta- unsaturated carboxylic acid ester and/or gamma-lactone derivatives
HUP9802187A3 (en) Method of producing 3-pentenic acid esters by carbonylation of alkoxynutenes
JPS5419950A (en) Synthetic method of methylenebisbenzophenone derivative
JPS53149965A (en) Novel lactone derivative and its preparation
PL364939A1 (en) Method for preparing 1-alkyl-pyrazol-5-carboxylic acid esters

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20110919

Year of fee payment: 15

LAPS Lapse due to unpaid annual fee