NL9301303A - Werkwijze voor de bereiding van L-fenylalanine methylester en werkwijze voor het daaruit bereiden van alfa-L-aspartyl-L-fenylalanine methylester. - Google Patents

Werkwijze voor de bereiding van L-fenylalanine methylester en werkwijze voor het daaruit bereiden van alfa-L-aspartyl-L-fenylalanine methylester. Download PDF

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Publication number
NL9301303A
NL9301303A NL9301303A NL9301303A NL9301303A NL 9301303 A NL9301303 A NL 9301303A NL 9301303 A NL9301303 A NL 9301303A NL 9301303 A NL9301303 A NL 9301303A NL 9301303 A NL9301303 A NL 9301303A
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NL
Netherlands
Prior art keywords
methyl ester
aspartyl
phenylalanine methyl
phenylalanine
water
Prior art date
Application number
NL9301303A
Other languages
English (en)
Dutch (nl)
Original Assignee
Miwon Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miwon Co filed Critical Miwon Co
Publication of NL9301303A publication Critical patent/NL9301303A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL9301303A 1992-08-27 1993-07-23 Werkwijze voor de bereiding van L-fenylalanine methylester en werkwijze voor het daaruit bereiden van alfa-L-aspartyl-L-fenylalanine methylester. NL9301303A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93596192A 1992-08-27 1992-08-27
US93596192 1992-08-27

Publications (1)

Publication Number Publication Date
NL9301303A true NL9301303A (nl) 1994-03-16

Family

ID=25467976

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9301303A NL9301303A (nl) 1992-08-27 1993-07-23 Werkwijze voor de bereiding van L-fenylalanine methylester en werkwijze voor het daaruit bereiden van alfa-L-aspartyl-L-fenylalanine methylester.

Country Status (8)

Country Link
US (1) US5334746A (it)
KR (1) KR970009594B1 (it)
CH (1) CH687825A5 (it)
DE (1) DE4328967A1 (it)
FR (1) FR2695128B1 (it)
GB (1) GB2270311B (it)
IT (1) IT1270852B (it)
NL (1) NL9301303A (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010096940A (ko) * 2000-04-19 2001-11-08 고두모 알파-엘-아스파틸-엘-페닐알라닌 메틸에스테르 염산염의제조방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786039A (en) * 1969-04-30 1974-01-15 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
US4680403A (en) * 1985-01-17 1987-07-14 Ajinomoto Co., Inc. Process for producing N-protected-α-L-aspartyl-L-phenylalanine methyl ester
US4684745A (en) * 1982-04-22 1987-08-04 Ajinomoto Company Incorporated Process for producing α-L-aspartyl-L-phenylalanine methyl ester for its hydrochloride
KR910007940B1 (ko) * 1989-04-14 1991-10-04 주식회사 미원 L-페닐알라닌 메틸에스테르 염산염의 정석법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
DE3600731A1 (de) * 1986-01-13 1987-07-16 Green Cross Korea Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
JPH0657719B2 (ja) * 1986-06-03 1994-08-03 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786039A (en) * 1969-04-30 1974-01-15 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
US4684745A (en) * 1982-04-22 1987-08-04 Ajinomoto Company Incorporated Process for producing α-L-aspartyl-L-phenylalanine methyl ester for its hydrochloride
US4680403A (en) * 1985-01-17 1987-07-14 Ajinomoto Co., Inc. Process for producing N-protected-α-L-aspartyl-L-phenylalanine methyl ester
KR910007940B1 (ko) * 1989-04-14 1991-10-04 주식회사 미원 L-페닐알라닌 메틸에스테르 염산염의 정석법

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 9248, Derwent World Patents Index; AN 92-395930 *

Also Published As

Publication number Publication date
KR940003905A (ko) 1994-03-14
CH687825A5 (de) 1997-02-28
FR2695128A1 (fr) 1994-03-04
ITTO930336A1 (it) 1994-11-14
IT1270852B (it) 1997-05-13
GB2270311A (en) 1994-03-09
GB2270311B (en) 1996-10-02
FR2695128B1 (fr) 1995-07-07
DE4328967A1 (de) 1994-03-03
KR970009594B1 (en) 1997-06-14
GB9317124D0 (en) 1993-09-29
US5334746A (en) 1994-08-02
ITTO930336A0 (it) 1993-05-14

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A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BN A decision not to publish the application has become irrevocable