DK0600762T3 - 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse - Google Patents

15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse

Info

Publication number
DK0600762T3
DK0600762T3 DK93402795.4T DK93402795T DK0600762T3 DK 0600762 T3 DK0600762 T3 DK 0600762T3 DK 93402795 T DK93402795 T DK 93402795T DK 0600762 T3 DK0600762 T3 DK 0600762T3
Authority
DK
Denmark
Prior art keywords
deoxypergualin
analogs
processes
preparation
therapeutic use
Prior art date
Application number
DK93402795.4T
Other languages
Danish (da)
English (en)
Inventor
Soth Samreth
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Application granted granted Critical
Publication of DK0600762T3 publication Critical patent/DK0600762T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
DK93402795.4T 1992-12-02 1993-11-17 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse DK0600762T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
DK0600762T3 true DK0600762T3 (da) 1996-11-11

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93402795.4T DK0600762T3 (da) 1992-12-02 1993-11-17 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse

Country Status (23)

Country Link
US (1) US5476870A (enExample)
EP (1) EP0600762B1 (enExample)
JP (1) JP2945261B2 (enExample)
KR (1) KR100187328B1 (enExample)
CN (1) CN1045431C (enExample)
AT (1) ATE140215T1 (enExample)
AU (1) AU664124B2 (enExample)
CA (1) CA2110437C (enExample)
CZ (1) CZ284958B6 (enExample)
DE (1) DE69303583T2 (enExample)
DK (1) DK0600762T3 (enExample)
ES (1) ES2092263T3 (enExample)
FI (1) FI112211B (enExample)
FR (1) FR2698628B1 (enExample)
GR (1) GR3021269T3 (enExample)
HU (1) HU218908B (enExample)
NO (1) NO180483C (enExample)
NZ (1) NZ250330A (enExample)
RU (1) RU2114823C1 (enExample)
SK (1) SK280286B6 (enExample)
TW (1) TW311132B (enExample)
UA (1) UA39920C2 (enExample)
ZA (1) ZA938821B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09511765A (ja) * 1995-02-10 1997-11-25 フルニエ・アンデュストリ・エ・サンテ 15−デオキシスペルグアリン類似体、その治療用途及びその調製方法
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
ES2139465T3 (es) * 1996-12-20 2000-02-01 Sueddeutsche Kalkstickstoff Piruvatos de creatina y procedimiento para su preparacion.
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
HK1043801A1 (zh) * 1998-08-28 2002-09-27 格莱风科学公司 精确长度的聚酰胺链、其制备方法和其与蛋白质的缀合物
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
CA2565633C (en) * 2004-05-05 2016-04-26 Atugen Ag Lipids, lipid complexes and use thereof
WO2006069782A2 (en) 2004-12-27 2006-07-06 Silence Therapeutics Ag. Lipid complexes coated with peg and their use
WO2010074591A1 (ru) 2008-12-24 2010-07-01 Закрытое Акционерное Общество "Beptekc" Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
JP5878172B2 (ja) * 2010-07-29 2016-03-08 ラボラトワール フルニエ エスアーエス 炎症性眼疾患の治療/予防用化合物
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
DE3770680D1 (de) * 1986-04-04 1991-07-18 Microbial Chem Res Found Spergualinaehnliche verbindungen und ihr herstellungsverfahren.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
CN1045431C (zh) 1999-10-06
HU218908B (hu) 2000-12-28
FR2698628B1 (fr) 1995-02-17
EP0600762B1 (fr) 1996-07-10
NO180483C (no) 1997-04-30
SK280286B6 (sk) 1999-11-08
TW311132B (enExample) 1997-07-21
RU2114823C1 (ru) 1998-07-10
FI935318A0 (fi) 1993-11-29
DE69303583T2 (de) 1996-11-21
CA2110437A1 (en) 1994-06-03
NO180483B (no) 1997-01-20
JPH06293728A (ja) 1994-10-21
CZ262293A3 (en) 1994-06-15
NO934338L (no) 1994-06-03
CN1095709A (zh) 1994-11-30
NZ250330A (en) 1995-06-27
DE69303583D1 (de) 1996-08-14
US5476870A (en) 1995-12-19
NO934338D0 (no) 1993-11-30
HK1000467A1 (en) 1998-03-27
FR2698628A1 (fr) 1994-06-03
HUT65782A (en) 1994-07-28
FI935318L (fi) 1994-06-03
ATE140215T1 (de) 1996-07-15
CA2110437C (en) 1999-04-13
EP0600762A1 (fr) 1994-06-08
AU5188393A (en) 1994-06-16
HU9303406D0 (en) 1994-03-28
CZ284958B6 (cs) 1999-04-14
JP2945261B2 (ja) 1999-09-06
SK135793A3 (en) 1994-06-08
ZA938821B (en) 1994-06-30
KR940014435A (ko) 1994-07-18
GR3021269T3 (en) 1997-01-31
KR100187328B1 (ko) 1999-05-15
UA39920C2 (uk) 2001-07-16
FI112211B (fi) 2003-11-14
AU664124B2 (en) 1995-11-02
ES2092263T3 (es) 1996-11-16

Similar Documents

Publication Publication Date Title
DK0600762T3 (da) 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse
DK0534859T3 (da) 3-Benzazepin-2-oner, som er substituerede med en benzocyklobutyl- eller indanylalkylaminoalkylgruppe, og som er anvendelige til behandling af cardiovaskulære sygdomme
DK0513543T3 (da) Amidinophenylalaninderivater, fremgangsmåde til deres fremstilling, deres anvendelse og antikoagulationsmidler med indehold deraf
DK0580502T3 (da) 3-(hydroxybenzylidenyl)-indolin-2-oner og farmaceutiske sammensætninger indeholdende disse
DK0618209T3 (da) Pyridothiadiaziner, fremgangsmåder til fremstilling heraf og farmaceutiske sammensætninger indeholdende dem
NO923803L (no) Karbamatderivater av 4-amino-3-isoksazolidinoner, 3-amino-1-hydroksypyrrolidin-2-oner og 1-amino-1-cyklopropankarboksylsyreanaloger, en fremgangsmaate for deres fremstilling og deres anvendelse som legemidler
PT84048A (fr) Procede de preparation de nouvelles phenyl-naphthyridines comportant un substituant methyle en position-3 et des medicaments qui en contiennent
DK39084A (da) 2-imino-pyrrolidiner, fremgangsmaade til deres fremstilling og terapeutiske midler indeholdende dem
NO881308L (no) Dihydropyridinamider, fremgangsmaate til deres fremstilling og deres anvendelse i legemidler.
DK0429370T3 (da) Hiditl ukendte thiophenderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
DK484684A (da) Derivater af 4-alkyl-2-hydroxy-3-methyl-2-phenylmorpholin, fremgangsmaade til deres fremstilling og deres terapeutiske anvendelse
HU896173D0 (enExample)
HU9202103D0 (en) Method for producing inosite-phosphate analogues and pharmaceutical preparatives containing these compounds
ATE100463T1 (de) Renin-hemmende aminooligohydroxy-derivate.
NO180085C (no) Acylsulfonamido- og sulfonamidopyridin-2-karboksylsyreestere og deres anvendelse som legemidler
DK0472181T3 (da) 5-Amino-substituerede adenosinanaloge som immunsuppresiva
DK0614890T3 (da) Fremgangsmåde til fremstilling af eventuelt 2-substituerede 5-chlorimidazoler.
FI924769A0 (fi) Foerfarande foer framstaellning av substituerade indoler
ATE158576T1 (de) Alpha-aryl-alpha-hydroxy-beta- imidazolinylpropionsäureamide
GR3021200T3 (en) (Cyclohexyl)-alken compounds, process for their preparation and pharmaceutical compositions containing them.
DK0471383T3 (da) Anvendelse af 5-vinylhalogen-aristeromycin/adenosin-analoge som immunosuppressiva
FR2481697B1 (enExample)
DK56089A (da) 1-aminophenyl-2-dimethylaminopropanonderivater, fremgangsmaade til deres fremstilling og anvendelse i terapien
ATE144257T1 (de) Tetrahydro-4-phenylimino-3-thiophenessigsäuren
DE58909563D1 (de) 3-Anilino-2-hydroxycarbonyl-4-thiophenessigsäuren