ATE140215T1 - 15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr - Google Patents

15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr

Info

Publication number
ATE140215T1
ATE140215T1 AT93402795T AT93402795T ATE140215T1 AT E140215 T1 ATE140215 T1 AT E140215T1 AT 93402795 T AT93402795 T AT 93402795T AT 93402795 T AT93402795 T AT 93402795T AT E140215 T1 ATE140215 T1 AT E140215T1
Authority
AT
Austria
Prior art keywords
deoxyspergualin
therapeutics
suppressing
production
immune defense
Prior art date
Application number
AT93402795T
Other languages
English (en)
Inventor
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
Soth Samreth
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Application granted granted Critical
Publication of ATE140215T1 publication Critical patent/ATE140215T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
AT93402795T 1992-12-02 1993-11-17 15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr ATE140215T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
ATE140215T1 true ATE140215T1 (de) 1996-07-15

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93402795T ATE140215T1 (de) 1992-12-02 1993-11-17 15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr

Country Status (24)

Country Link
US (1) US5476870A (de)
EP (1) EP0600762B1 (de)
JP (1) JP2945261B2 (de)
KR (1) KR100187328B1 (de)
CN (1) CN1045431C (de)
AT (1) ATE140215T1 (de)
AU (1) AU664124B2 (de)
CA (1) CA2110437C (de)
CZ (1) CZ284958B6 (de)
DE (1) DE69303583T2 (de)
DK (1) DK0600762T3 (de)
ES (1) ES2092263T3 (de)
FI (1) FI112211B (de)
FR (1) FR2698628B1 (de)
GR (1) GR3021269T3 (de)
HK (1) HK1000467A1 (de)
HU (1) HU218908B (de)
NO (1) NO180483C (de)
NZ (1) NZ250330A (de)
RU (1) RU2114823C1 (de)
SK (1) SK280286B6 (de)
TW (1) TW311132B (de)
UA (1) UA39920C2 (de)
ZA (1) ZA938821B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0755380T3 (da) * 1995-02-10 1999-06-23 Fournier Ind & Sante 15-deoxyspergualin-analoge, deres terapeutiske anvendelse og fremgangsmåde til fremstilling deraf
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
CN1330675A (zh) * 1998-08-28 2002-01-09 格莱风科学公司 精确长度的聚酰胺链、其制备方法和其与蛋白质的缀合物
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
MXPA06012722A (es) * 2004-05-05 2007-02-14 Atugen Ag Lipidos, complejos de lipido y su uso.
KR101366482B1 (ko) 2004-12-27 2014-02-21 사일런스 테라퓨틱스 아게 코팅된 지질 복합체 및 이들의 용도
WO2010074591A1 (ru) 2008-12-24 2010-07-01 Закрытое Акционерное Общество "Beptekc" Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
KR20130099926A (ko) * 2010-07-29 2013-09-06 라보라뚜와르 푸르니에 에스.아. 염증성 눈질환의 치료/예방용 화합물
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
EP0241797B1 (de) * 1986-04-04 1991-06-12 Microbial Chemistry Research Foundation Spergualinähnliche Verbindungen und ihr Herstellungsverfahren
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
EP0600762A1 (de) 1994-06-08
SK280286B6 (sk) 1999-11-08
HU218908B (hu) 2000-12-28
ES2092263T3 (es) 1996-11-16
CZ284958B6 (cs) 1999-04-14
TW311132B (de) 1997-07-21
CN1045431C (zh) 1999-10-06
CA2110437C (en) 1999-04-13
FR2698628B1 (fr) 1995-02-17
HK1000467A1 (en) 1998-03-27
NO180483C (no) 1997-04-30
SK135793A3 (en) 1994-06-08
DK0600762T3 (da) 1996-11-11
NO934338D0 (no) 1993-11-30
ZA938821B (en) 1994-06-30
EP0600762B1 (de) 1996-07-10
FI112211B (fi) 2003-11-14
JPH06293728A (ja) 1994-10-21
NO180483B (no) 1997-01-20
FI935318A0 (fi) 1993-11-29
AU5188393A (en) 1994-06-16
FR2698628A1 (fr) 1994-06-03
AU664124B2 (en) 1995-11-02
GR3021269T3 (en) 1997-01-31
UA39920C2 (uk) 2001-07-16
DE69303583T2 (de) 1996-11-21
JP2945261B2 (ja) 1999-09-06
KR100187328B1 (ko) 1999-05-15
NZ250330A (en) 1995-06-27
DE69303583D1 (de) 1996-08-14
CN1095709A (zh) 1994-11-30
CA2110437A1 (en) 1994-06-03
US5476870A (en) 1995-12-19
NO934338L (no) 1994-06-03
RU2114823C1 (ru) 1998-07-10
FI935318A (fi) 1994-06-03
CZ262293A3 (en) 1994-06-15
HU9303406D0 (en) 1994-03-28
HUT65782A (en) 1994-07-28
KR940014435A (ko) 1994-07-18

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