GB9004483D0
(en)
*
|
1990-02-28 |
1990-04-25 |
Erba Carlo Spa |
New aryl-and heteroarylethenylene derivatives and process for their preparation
|
US5587385A
(en)
*
|
1991-12-24 |
1996-12-24 |
Farmitalia Carlo Erba S.R.L. |
Arylidene-heterocyclic derivatives and process for their preparation
|
US5981569A
(en)
*
|
1992-11-13 |
1999-11-09 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease
|
US5712395A
(en)
*
|
1992-11-13 |
1998-01-27 |
Yissum Research Development Corp. |
Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis
|
US5763441A
(en)
*
|
1992-11-13 |
1998-06-09 |
Sugen, Inc. |
Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis
|
US5792771A
(en)
*
|
1992-11-13 |
1998-08-11 |
Sugen, Inc. |
Quinazoline compounds and compositions thereof for the treatment of disease
|
GB9326136D0
(en)
*
|
1993-12-22 |
1994-02-23 |
Erba Carlo Spa |
Biologically active 3-substituted oxindole derivatives useful as anti-angiogenic agents
|
GB9406137D0
(en)
*
|
1994-03-28 |
1994-05-18 |
Erba Carlo Spa |
N-substituted beta-aryl- and betaheteroaryl-alpha-cyanoacrylamide derivatives and process for their preparation
|
GB9412719D0
(en)
*
|
1994-06-24 |
1994-08-17 |
Erba Carlo Spa |
Substituted azaindolylidene compounds and process for their preparation
|
GB9423997D0
(en)
*
|
1994-11-28 |
1995-01-11 |
Erba Carlo Spa |
Substituted 3-arylidene-7-azaoxindole compounds and process for their preparation
|
WO1996032391A1
(de)
*
|
1995-04-11 |
1996-10-17 |
Lonza Ag |
Verfahren zur herstellung von azaindolen mit aktiviertem kupferchromit katalysator durch katalytische dehydrocyclisierung von alkyl-pyridylaminen (pyridopyridinen)
|
US5880141A
(en)
*
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
AU6112896A
(en)
*
|
1995-06-07 |
1996-12-30 |
Sugen, Inc. |
Tyrphostin-like compounds for the treatment of cell prolifer ative disorders or cell differentiation disorders
|
US5650415A
(en)
*
|
1995-06-07 |
1997-07-22 |
Sugen, Inc. |
Quinoline compounds
|
US6147106A
(en)
|
1997-08-20 |
2000-11-14 |
Sugen, Inc. |
Indolinone combinatorial libraries and related products and methods for the treatment of disease
|
US6906093B2
(en)
|
1995-06-07 |
2005-06-14 |
Sugen, Inc. |
Indolinone combinatorial libraries and related products and methods for the treatment of disease
|
US5773459A
(en)
*
|
1995-06-07 |
1998-06-30 |
Sugen, Inc. |
Urea- and thiourea-type compounds
|
US5763470A
(en)
*
|
1995-06-07 |
1998-06-09 |
Sugen Inc. |
Benzopyran compounds and methods for their use
|
WO1996040648A1
(en)
*
|
1995-06-07 |
1996-12-19 |
Sugen, Inc. |
Quinazolines and pharmaceutical compositions
|
US6316635B1
(en)
|
1995-06-07 |
2001-11-13 |
Sugen, Inc. |
2-indolinone derivatives as modulators of protein kinase activity
|
US5710173A
(en)
*
|
1995-06-07 |
1998-01-20 |
Sugen, Inc. |
Thienyl compounds for inhibition of cell proliferative disorders
|
US6716575B2
(en)
|
1995-12-18 |
2004-04-06 |
Sugen, Inc. |
Diagnosis and treatment of AUR1 and/or AUR2 related disorders
|
US7119174B2
(en)
|
1995-12-18 |
2006-10-10 |
Sugen, Inc. |
Diagnosis and treatment of AUR1 and/or AUR2 related disorders
|
US6696448B2
(en)
|
1996-06-05 |
2004-02-24 |
Sugen, Inc. |
3-(piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors
|
US6682921B1
(en)
|
1996-08-21 |
2004-01-27 |
New York University |
Crystals of the tyrosine kinase domain of non-insulin receptor tyrosine kinases
|
US6818440B2
(en)
|
1997-04-28 |
2004-11-16 |
Sugen, Inc. |
Diagnosis and treatment of alk-7 related disorders
|
AR012634A1
(es)
|
1997-05-02 |
2000-11-08 |
Sugen Inc |
Compuesto basado en quinazolina, composicion famaceutica que lo comprende, metodo para sintetizarlo, su uso, metodos de modulacion de la funcion deserina/treonina proteinaquinasa con dicho compuesto y metodo in vitro para identificar compuestos que modulan dicha funcion
|
ES2239393T3
(es)
*
|
1997-05-07 |
2005-09-16 |
Sugen, Inc. |
Derivados de 2-indolinona utilizados como moduladores de la actividad de la proteina-quinasa.
|
US6316429B1
(en)
|
1997-05-07 |
2001-11-13 |
Sugen, Inc. |
Bicyclic protein kinase inhibitors
|
US6486185B1
(en)
|
1997-05-07 |
2002-11-26 |
Sugen, Inc. |
3-heteroarylidene-2-indolinone protein kinase inhibitors
|
US6228641B1
(en)
|
1997-05-20 |
2001-05-08 |
Sugen, Inc. |
Diagnosis and treatment of PTP04 related disorders
|
US7115710B2
(en)
|
1997-06-11 |
2006-10-03 |
Sugen, Inc. |
Diagnosis and treatment of PTP related disorders
|
US6342593B1
(en)
|
1997-06-11 |
2002-01-29 |
Sugen, Inc. |
Diagnosis and treatment of ALP related disorders
|
US6987113B2
(en)
|
1997-06-11 |
2006-01-17 |
Sugen, Inc. |
Tyrosine kinase inhibitors
|
US6388063B1
(en)
|
1997-06-18 |
2002-05-14 |
Sugen, Inc. |
Diagnosis and treatment of SAD related disorders
|
US6114371A
(en)
*
|
1997-06-20 |
2000-09-05 |
Sugen, Inc. |
3-(cyclohexanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors
|
US6130238A
(en)
*
|
1997-06-20 |
2000-10-10 |
Sugen, Inc. |
3-(cyclohexanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors
|
US6313158B1
(en)
|
1997-06-20 |
2001-11-06 |
Sugen, Inc. |
Bioavailability of 3-heteroarylidenyl-2-indolinones active as protein tyrosine kinase inhibitors
|
US6051593A
(en)
*
|
1997-06-20 |
2000-04-18 |
Sugen, Inc. |
3-(cycloalkanoheteroarylidenyl)-2- indolinone protein tyrosine kinase inhibitors
|
US6235769B1
(en)
|
1997-07-03 |
2001-05-22 |
Sugen, Inc. |
Methods of preventing and treating neurological disorders with compounds that modulate the function of the C-RET receptor protein tyrosine kinase
|
WO1999007701A1
(en)
|
1997-08-05 |
1999-02-18 |
Sugen, Inc. |
Tricyclic quinoxaline derivatives as protein tyrosine kinase inhibitors
|
US20040067531A1
(en)
*
|
1997-08-20 |
2004-04-08 |
Sugen, Inc. |
Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
|
US6133305A
(en)
*
|
1997-09-26 |
2000-10-17 |
Sugen, Inc. |
3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity
|
EP1017384B1
(de)
*
|
1997-09-26 |
2004-11-10 |
Zentaris GmbH |
Azabenzimidazol-verbindungen zur modulation der serin/threonin protein-kinase funktion
|
UA71555C2
(en)
|
1997-10-06 |
2004-12-15 |
Zentaris Gmbh |
Methods for modulating function of serine/threonine protein kinases by 5-azaquinoline derivatives
|
US6225346B1
(en)
|
1997-10-24 |
2001-05-01 |
Sugen, Inc. |
Tyrphostin like compounds
|
US5935626A
(en)
*
|
1997-11-24 |
1999-08-10 |
Moorman Manufacturing Company |
Weather resistant mineral feeds and methods of making same
|
EP1049786A2
(de)
|
1998-01-21 |
2000-11-08 |
Sugen, Inc. |
Menschliche orthologe von wart
|
US6531502B1
(en)
|
1998-01-21 |
2003-03-11 |
Sugen, Inc. |
3-Methylidenyl-2-indolinone modulators of protein kinase
|
AU3363599A
(en)
*
|
1998-03-26 |
1999-10-18 |
Max-Planck Institut Fur Biochemie |
Heterocyclic families of compounds for the modulation of tyrosine protein kinase
|
DE69926742T2
(de)
|
1998-04-14 |
2006-06-14 |
Sugen Inc |
Ste20-verwandte proteinkinasen
|
US6569868B2
(en)
|
1998-04-16 |
2003-05-27 |
Sugen, Inc. |
2-indolinone derivatives as modulators of protein kinase activity
|
US6395734B1
(en)
|
1998-05-29 |
2002-05-28 |
Sugen, Inc. |
Pyrrole substituted 2-indolinone protein kinase inhibitors
|
EP1117397A1
(de)
|
1998-08-31 |
2001-07-25 |
Sugen, Inc. |
Geometrisch verhinderte 2-indolinonderivate als modulatoren der protein kinase aktivität
|
US6680335B2
(en)
|
1998-09-28 |
2004-01-20 |
Sugen, Inc. |
Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
|
US6153634A
(en)
|
1998-12-17 |
2000-11-28 |
Hoffmann-La Roche Inc. |
4,5-azolo-oxindoles
|
ES2301255T3
(es)
|
1998-12-17 |
2008-06-16 |
F. Hoffmann-La Roche Ag |
4,5-pirazinaxindoles como inhibidores de proteinoquinasas.
|
AU770375B2
(en)
|
1998-12-17 |
2004-02-19 |
F. Hoffmann-La Roche Ag |
4-alkenyl (and alkynyl) oxindoles as inhibitors of cyclin-dependent kinases, in particular CDK2
|
AU760039B2
(en)
|
1998-12-17 |
2003-05-08 |
F. Hoffmann-La Roche Ag |
4-aryloxindoles as inhibitors of JNK protein kinases
|
EP1630559A3
(de)
*
|
1998-12-30 |
2006-06-07 |
Sugen, Inc. |
PYK2 (RAFTK) und Entzündung
|
JP2002540096A
(ja)
*
|
1999-03-24 |
2002-11-26 |
スージェン・インコーポレーテッド |
キナーゼ阻害剤としてのインドリノン化合物
|
US6689806B1
(en)
|
1999-03-24 |
2004-02-10 |
Sugen, Inc. |
Indolinone compounds as kinase inhibitors
|
US6297238B1
(en)
|
1999-04-06 |
2001-10-02 |
Basf Aktiengesellschaft |
Therapeutic agents
|
DK1165544T3
(da)
*
|
1999-04-06 |
2003-12-01 |
Abbott Gmbh & Co Kg |
Substituerede 1,4-dihydroindeno[1,2-c]pyrazoler som inhibitorer af tyrosinkinase
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
JP2003512838A
(ja)
|
1999-10-22 |
2003-04-08 |
ファルマシア・アンド・アップジョン・カンパニー |
ショウジョウバエgタンパク質結合レセプター、核酸、およびそれに関連する方法。
|
US6878733B1
(en)
|
1999-11-24 |
2005-04-12 |
Sugen, Inc. |
Formulations for pharmaceutical agents ionizable as free acids or free bases
|
US20020002169A1
(en)
|
1999-12-08 |
2002-01-03 |
Griffin John H. |
Protein kinase inhibitors
|
US6313310B1
(en)
|
1999-12-15 |
2001-11-06 |
Hoffmann-La Roche Inc. |
4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles
|
US20020010203A1
(en)
|
1999-12-22 |
2002-01-24 |
Ken Lipson |
Methods of modulating c-kit tyrosine protein kinase function with indolinone compounds
|
EP1259234B9
(de)
*
|
1999-12-30 |
2007-02-14 |
Sugen, Inc. |
3-heteroarylidenyl-2-indolinon derivate mit protein kinase modulierender activity und zur verwendung in der krebschemotherapie
|
IL151045A0
(en)
|
2000-02-07 |
2003-04-10 |
Abbott Gmbh & Co Kg |
2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
|
WO2001060814A2
(en)
*
|
2000-02-15 |
2001-08-23 |
Sugen, Inc. |
Pyrrole substituted 2-indolinone protein kinase inhibitors
|
ATE297395T1
(de)
*
|
2000-02-28 |
2005-06-15 |
Sugen Inc |
3-(pyrolyllacton)-2-indolinon verbindungen zur verwendung als kinase-hemmstoffe
|
MY128450A
(en)
|
2000-05-24 |
2007-02-28 |
Upjohn Co |
1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
|
CA2410509A1
(en)
|
2000-06-02 |
2001-12-13 |
Sugen, Inc. |
Indolinone derivatives as protein kinase/phosphatase inhibitors
|
US6335342B1
(en)
|
2000-06-19 |
2002-01-01 |
Pharmacia & Upjohn S.P.A. |
Azaindole derivatives, process for their preparation, and their use as antitumor agents
|
US6726918B1
(en)
|
2000-07-05 |
2004-04-27 |
Oculex Pharmaceuticals, Inc. |
Methods for treating inflammation-mediated conditions of the eye
|
AU3649502A
(en)
|
2000-11-29 |
2002-06-11 |
Oculex Pharm Inc |
Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
|
US6582919B2
(en)
|
2001-06-11 |
2003-06-24 |
Response Genetics, Inc. |
Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates
|
AR042586A1
(es)
|
2001-02-15 |
2005-06-29 |
Sugen Inc |
3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
|
MXPA03008560A
(es)
|
2001-03-22 |
2004-06-30 |
Abbot Gmbh & Co Kg |
Pirazolopirimidinas como agentes terapeuticos.
|
US6599902B2
(en)
|
2001-05-30 |
2003-07-29 |
Sugen, Inc. |
5-aralkysufonyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
|
WO2002102854A2
(en)
|
2001-06-20 |
2002-12-27 |
Morphosys Ag |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
AR038957A1
(es)
*
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
Terapia de combinacion para el tratamiento del cancer
|
US6765012B2
(en)
|
2001-09-27 |
2004-07-20 |
Allergan, Inc. |
3-(Arylamino)methylene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
|
US7005444B2
(en)
|
2001-09-27 |
2006-02-28 |
Allergan, Inc. |
3-(heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors
|
EP1434774A1
(de)
|
2001-10-10 |
2004-07-07 |
Sugen, Inc. |
3-(4-substituierte heterocyclyl)-pyrrol-2-ylmethylidene)-2-indolinone derivate als protein-kinase-inhibitoren
|
WO2003082869A1
(en)
*
|
2002-03-28 |
2003-10-09 |
Eisai Co., Ltd. |
Azaindoles as inhibitors of c-jun n-terminal kinases
|
US6541504B1
(en)
|
2002-04-03 |
2003-04-01 |
Allergan Sales, Llc |
(3Z)-3-(2,3-dihydro-1H-inden-1-ylidene)-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
|
MXPA04009434A
(es)
*
|
2002-04-03 |
2005-01-25 |
Allergan Inc |
(3z)-3- (3 -hidroisobenzofuran- 1-iliden) -1, 3-dihidro- 2h-indol -2-onas como inhibidores de cinasa.
|
US7700571B2
(en)
|
2002-06-05 |
2010-04-20 |
Genentech, Inc. |
Compositions and methods for liver growth and liver protection
|
US8450302B2
(en)
|
2002-08-02 |
2013-05-28 |
Ab Science |
2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
|
ES2294344T3
(es)
|
2002-08-02 |
2008-04-01 |
Ab Science |
2-(3-aminoaril)amino-4-aril-tiazoles y su utilizacion como inhibidores de c-kit.
|
US6699863B1
(en)
|
2002-11-27 |
2004-03-02 |
Allergan, Inc. |
Kinase inhibitors for the treatment of disease
|
US6747025B1
(en)
|
2002-11-27 |
2004-06-08 |
Allergan, Inc. |
Kinase inhibitors for the treatment of disease
|
US20050048099A1
(en)
|
2003-01-09 |
2005-03-03 |
Allergan, Inc. |
Ocular implant made by a double extrusion process
|
ES2401330T3
(es)
|
2003-02-26 |
2013-04-18 |
Sugen, Inc. |
Compuesto de heteroarilamino inhibidores de proteín quinasas
|
US7157577B2
(en)
|
2003-03-07 |
2007-01-02 |
Sugen Inc. |
5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors
|
JP2007501229A
(ja)
|
2003-08-06 |
2007-01-25 |
スゲン,インコーポレイティド |
強力なプロテインキナーゼ阻害剤としての幾何学的に束縛された3−シクロペンチリデン−1,3−ジヒドロインドール−2−オン類
|
CN1898240B
(zh)
*
|
2003-10-15 |
2011-08-03 |
Osi制药公司 |
咪唑并吡嗪类酪氨酸激酶抑制剂
|
CN1950347B
(zh)
|
2003-10-23 |
2012-04-04 |
Ab科学公司 |
作为酪氨酸激酶抑制剂的2-氨基芳基噁唑化合物
|
CA2550361C
(en)
|
2003-12-19 |
2014-04-29 |
Prabha Ibrahim |
Compounds and methods for development of ret modulators
|
BRPI0509576A
(pt)
|
2004-04-02 |
2007-05-29 |
Osi Pharm Inc |
composto, método de tratamento de um paciente tendo uma condição que é mediada pela atividade de proteìna quinase, e, composição farmacêutica
|
US7915443B2
(en)
|
2006-11-16 |
2011-03-29 |
Allergan, Inc. |
Sulfoximines as kinase inhibitors
|
US8685435B2
(en)
|
2004-04-30 |
2014-04-01 |
Allergan, Inc. |
Extended release biodegradable ocular implants
|
US20050244469A1
(en)
|
2004-04-30 |
2005-11-03 |
Allergan, Inc. |
Extended therapeutic effect ocular implant treatments
|
WO2005113561A1
(en)
*
|
2004-05-20 |
2005-12-01 |
Sugen, Inc. |
Cyclicsulfonate pyrrole indolinones as kinase inhibitors
|
US7498342B2
(en)
|
2004-06-17 |
2009-03-03 |
Plexxikon, Inc. |
Compounds modulating c-kit activity
|
AU2005265017A1
(en)
*
|
2004-06-17 |
2006-01-26 |
Plexxikon, Inc. |
Azaindoles modulating c-kit activity and uses therefor
|
TW200613306A
(en)
|
2004-07-20 |
2006-05-01 |
Osi Pharm Inc |
Imidazotriazines as protein kinase inhibitors
|
US20080242704A1
(en)
|
2005-04-04 |
2008-10-02 |
Ab Science |
Substituted Oxazole Derivatives and their Use as Tyrosine Kinase Inhibitors
|
MX2007014377A
(es)
*
|
2005-05-17 |
2008-02-06 |
Plexxikon Inc |
Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina.
|
US7566721B2
(en)
*
|
2005-08-08 |
2009-07-28 |
Osi Pharmaceuticals, Inc. |
Substituted thienol[2,3-d]pyrimidines as kinase inhibitors
|
CN100519524C
(zh)
*
|
2005-09-29 |
2009-07-29 |
中国人民解放军军事医学科学院毒物药物研究所 |
吲哚丙烯酸衍生物及其用于制备免疫抑制剂的用途
|
US7371862B2
(en)
*
|
2005-11-11 |
2008-05-13 |
Pfizer Italia S.R.L. |
Azaindolylidene derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
|
AR057960A1
(es)
|
2005-12-02 |
2007-12-26 |
Osi Pharm Inc |
Inhibidores de proteina quinasa biciclicos
|
US8575164B2
(en)
*
|
2005-12-19 |
2013-11-05 |
OSI Pharmaceuticals, LLC |
Combination cancer therapy
|
WO2007076320A2
(en)
*
|
2005-12-22 |
2007-07-05 |
Smithkline Beecham Corporation |
Compounds
|
US8338415B2
(en)
|
2006-01-24 |
2012-12-25 |
Allergan, Inc. |
Substituted 3-(5-membered unsaturated heterocyclyl-1, 3-dihydro-indol-2-one's and derivatives thereof as kinase inhibitors
|
US7977351B2
(en)
|
2006-03-22 |
2011-07-12 |
Allergan, Inc. |
Heteroaryl dihydroindolones as kinase inhibitors
|
BRPI0622054B8
(pt)
|
2006-09-22 |
2021-05-25 |
Oxford Amherst Llc |
composto e composição farmacêutica
|
US8558002B2
(en)
|
2006-11-16 |
2013-10-15 |
Allergan, Inc. |
Sulfoximines as kinase inhibitors
|
WO2008063888A2
(en)
|
2006-11-22 |
2008-05-29 |
Plexxikon, Inc. |
Compounds modulating c-fms and/or c-kit activity and uses therefor
|
US20120101113A1
(en)
|
2007-03-28 |
2012-04-26 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
MX2009010284A
(es)
*
|
2007-03-28 |
2010-01-29 |
Pharmacyclics Inc |
Inhibidores de la tirosina-cinasa de bruton.
|
US8663915B2
(en)
|
2007-04-13 |
2014-03-04 |
Agency For Science, Technology And Research |
Methods of controlling tumorigenesis and diagnosing the risk thereof
|
US8231892B2
(en)
|
2007-05-24 |
2012-07-31 |
Allergan, Inc. |
Biodegradable drug delivery system
|
EP2170830B1
(de)
|
2007-07-17 |
2014-10-15 |
Plexxikon, Inc. |
2-FLUORO-BENZOSULFONAMID-VERBINDUNGEN ALS Raf-KINASE-MODULATOREN
|
US8969313B2
(en)
|
2007-11-02 |
2015-03-03 |
Agency For Science, Technology And Research |
Methods and compounds for preventing and treating a tumour
|
WO2009091939A1
(en)
*
|
2008-01-18 |
2009-07-23 |
Osi Pharmaceuticals, Inc. |
Imidazopyrazinol derivatives for the treatment of cancers
|
JP2011520970A
(ja)
*
|
2008-05-19 |
2011-07-21 |
オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド |
置換されたイミダゾピラジン類およびイミダゾトリアジン類
|
US20100101977A1
(en)
*
|
2008-06-05 |
2010-04-29 |
United Comb & Novelty Corporation |
Stackable Packaging For Lipped Containers
|
MX2011000661A
(es)
*
|
2008-07-16 |
2011-05-25 |
Pharmacyclics Inc |
Inhibidores de tirosina cinasa de bruton para el tratamiento de tumores solidos.
|
MY172424A
(en)
|
2009-04-03 |
2019-11-25 |
Hoffmann La Roche |
Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
|
CA2752826A1
(en)
|
2009-04-20 |
2010-10-28 |
OSI Pharmaceuticals, LLC |
Preparation of c-pyrazine-methylamines
|
JP2012526138A
(ja)
*
|
2009-05-07 |
2012-10-25 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
副腎皮質癌を治療するためのosi−906の使用
|
WO2011028995A1
(en)
|
2009-09-03 |
2011-03-10 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
US9340555B2
(en)
|
2009-09-03 |
2016-05-17 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
BR112012012156A2
(pt)
|
2009-11-06 |
2015-09-08 |
Plexxikon Inc |
compostos e métodos para modulação de cinase, e indicações para esta
|
EP2558099A4
(de)
*
|
2009-11-16 |
2013-07-17 |
Univ California San Francisco |
Kinase-inhibitoren
|
US9265739B2
(en)
|
2010-06-02 |
2016-02-23 |
The Trustees Of The University Of Pennsylvania |
Methods and use of compounds that bind to HER2/neu receptor complex
|
US8993634B2
(en)
|
2010-06-02 |
2015-03-31 |
The Trustees Of The University Of Pennsylvania |
Methods and use of compounds that bind to Her2/neu receptor complex
|
IL300955A
(en)
|
2010-06-03 |
2023-04-01 |
Pharmacyclics Llc |
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-H1-pyrazolo[4,3-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1- Indicated for use as a drug to treat chronic lymphocytic leukemia or small lymphocytic lymphoma
|
WO2011159726A2
(en)
|
2010-06-14 |
2011-12-22 |
The Scripps Research Institute |
Reprogramming of cells to a new fate
|
TR201816421T4
(tr)
|
2011-02-07 |
2018-11-21 |
Plexxikon Inc |
Kinaz modülasyonu için bileşikler ve metotlar ve bunların endikasyonları.
|
AR085279A1
(es)
|
2011-02-21 |
2013-09-18 |
Plexxikon Inc |
Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
|
KR20140048968A
(ko)
|
2011-07-13 |
2014-04-24 |
파마시클릭스, 인코포레이티드 |
브루톤형 티로신 키나제의 억제제
|
US8377946B1
(en)
|
2011-12-30 |
2013-02-19 |
Pharmacyclics, Inc. |
Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
|
US9150570B2
(en)
|
2012-05-31 |
2015-10-06 |
Plexxikon Inc. |
Synthesis of heterocyclic compounds
|
UA114421C2
(uk)
|
2012-06-04 |
2017-06-12 |
Фармасайклікс Ллс |
Кристалічна форма інгібітору тирозинкінази брутона
|
CN104704129A
(zh)
|
2012-07-24 |
2015-06-10 |
药品循环公司 |
与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变
|
EP2890706A1
(de)
|
2012-08-31 |
2015-07-08 |
Westfälische Wilhelms-Universität Münster |
Verfahren und peptide zur vorbeugung und behandlung von mit bcr-abl und c-abl assoziierten krankheiten
|
MX2015006168A
(es)
|
2012-11-15 |
2015-08-10 |
Pharmacyclics Inc |
Compuestos de pirrolopirimidina como inhibidores de quinasas.
|
US9468681B2
(en)
|
2013-03-01 |
2016-10-18 |
California Institute Of Technology |
Targeted nanoparticles
|
TWI649081B
(zh)
|
2013-08-02 |
2019-02-01 |
製藥公司 |
治療固態腫瘤之方法
|
US9415050B2
(en)
|
2013-08-12 |
2016-08-16 |
Pharmacyclics Llc |
Methods for the treatment of HER2 amplified cancer
|
MA38961A1
(fr)
|
2013-09-30 |
2018-05-31 |
Pharmacyclics Llc |
Composés 3-phenyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine substitués inhibiteurs de la tyrosine kinase de bruton utilisés pour traiter par exemple les maladies auto-immunes, respiratoires et inflammatoires, cancer, mastocytose et osteoporose
|
WO2015143400A1
(en)
|
2014-03-20 |
2015-09-24 |
Pharmacyclics, Inc. |
Phospholipase c gamma 2 and resistance associated mutations
|
CA2959602A1
(en)
|
2014-08-01 |
2016-02-04 |
Pharmacyclics Llc |
Inhibitors of bruton's tyrosine kinase
|
BR112017002231A2
(pt)
|
2014-08-07 |
2018-07-17 |
Pharmacyclics Llc |
novas formulações de um inibidor de tirosina cinase de bruton
|
SG11201707122QA
(en)
|
2015-03-03 |
2017-09-28 |
Pharmacyclics Llc |
Pharmaceutical formulations of bruton's tyrosine kinase inhibtor
|
EP3795609B1
(de)
|
2015-07-01 |
2024-04-03 |
California Institute of Technology |
Kationische schleimsäurepolymerbasierte abgabesysteme
|
CN110944634A
(zh)
|
2017-06-30 |
2020-03-31 |
加利福尼亚大学董事会 |
用于调节毛发生长的组合物和方法
|