ATE302269T1 - Ste20-verwandte proteinkinasen - Google Patents

Ste20-verwandte proteinkinasen

Info

Publication number
ATE302269T1
ATE302269T1 AT99918539T AT99918539T ATE302269T1 AT E302269 T1 ATE302269 T1 AT E302269T1 AT 99918539 T AT99918539 T AT 99918539T AT 99918539 T AT99918539 T AT 99918539T AT E302269 T1 ATE302269 T1 AT E302269T1
Authority
AT
Austria
Prior art keywords
ste20
protein kinases
nucleic acid
acid molecules
molecules encoding
Prior art date
Application number
AT99918539T
Other languages
English (en)
Inventor
Gregory Plowman
Ricardo Martinez
David Whyte
Original Assignee
Sugen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen Inc filed Critical Sugen Inc
Application granted granted Critical
Publication of ATE302269T1 publication Critical patent/ATE302269T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99918539T 1998-04-14 1999-04-13 Ste20-verwandte proteinkinasen ATE302269T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8178498P 1998-04-14 1998-04-14
PCT/US1999/008150 WO1999053036A2 (en) 1998-04-14 1999-04-13 Ste20-related protein kinases

Publications (1)

Publication Number Publication Date
ATE302269T1 true ATE302269T1 (de) 2005-09-15

Family

ID=22166386

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99918539T ATE302269T1 (de) 1998-04-14 1999-04-13 Ste20-verwandte proteinkinasen

Country Status (10)

Country Link
US (5) US6680170B2 (de)
EP (1) EP1073723B1 (de)
JP (1) JP2002522009A (de)
AT (1) ATE302269T1 (de)
AU (1) AU3642499A (de)
CA (1) CA2369172A1 (de)
DE (1) DE69926742T2 (de)
DK (1) DK1073723T3 (de)
ES (1) ES2248997T3 (de)
WO (1) WO1999053036A2 (de)

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US7078182B1 (en) * 1998-04-14 2006-07-18 Board Of Regents, The University Of Texas System TAO protein kinase polypeptides and methods of use therefor
US6013500A (en) * 1998-05-21 2000-01-11 The Trustees Of Columbia University In The City Of New York PAK4, a novel gene encoding a serine/threonine kinase
WO2000015805A1 (en) * 1998-09-10 2000-03-23 Smithkline Beecham P.L.C. Use of protein kinase kiaa0551 as pharmaceutical
CA2362936A1 (en) * 1999-02-19 2000-08-24 Mcmaster University A caspase activated protein kinase
WO2000060062A2 (en) * 1999-04-01 2000-10-12 Astrazeneca Uk Limited Human signal transduction serine/threonine protein kinase
US6558903B1 (en) * 1999-06-30 2003-05-06 Millennium Pharmaceuticals, Inc. Kinases and uses thereof
AU6181000A (en) * 1999-07-29 2001-02-19 Chugai Research Institute For Molecular Medicine, Inc. Novel genes encoding protein kinase/protein phosphatase
US20030104622A1 (en) * 1999-09-01 2003-06-05 Robbins Paul D. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
US6861239B1 (en) 1999-09-20 2005-03-01 New York University Genes and polynucleotides associated with ultraviolet radiation-mediated skin damage and uses thereof
EP1244774A2 (de) * 1999-11-15 2002-10-02 Pharmacia Italia S.p.A. Pak5 ein mitglied der p21-aktivierte kinase (pak) protein familie und zugehöriger verfahren
AU2001234544A1 (en) * 2000-01-25 2001-08-07 Sugen, Inc. Novel human protein kinases and protein kinase-like enzymes
AU2002223950A1 (en) * 2000-09-20 2002-04-02 Qlt Inc. Cancer associated protein kinases and their uses
CA2433753A1 (en) * 2001-01-12 2002-07-18 Incyte Genomics, Inc. Molecules for disease detection and treatment
US7265214B2 (en) * 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
US7482138B2 (en) 2001-12-28 2009-01-27 The Trustees Of Columbia University In The City Of New York PAK5-related compositions and methods
PT1539956E (pt) * 2002-07-05 2011-03-16 Sugen Inc Gef-h1b: biomarcadores, complexos, ensaios e utilizações terapêuticas dos mesmos
GB0220770D0 (en) * 2002-09-06 2002-10-16 Ares Trading Sa Proteins
DE60335925D1 (de) * 2002-11-27 2011-03-10 Sugen Inc Phosphospezifische PAK-Antikörper und diagnostische Kits
GB2396615A (en) * 2002-12-23 2004-06-30 Devgen Nv Kinase sequences useful for developing compounds for the prevention and/or treatment of metabolic diseases
WO2004056982A2 (en) * 2002-12-23 2004-07-08 Devgen Nv Kinase sequences
WO2004092395A2 (en) * 2003-04-08 2004-10-28 Baylor College Of Medicine Modulators of telomere stability
NZ545385A (en) * 2003-08-13 2010-12-24 Novartis Vaccines & Diagnostic Prion-specific peptide reagents
US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
AU2004275876B2 (en) * 2003-09-25 2011-03-31 Coley Pharmaceutical Gmbh Nucleic acid-lipophilic conjugates
WO2005111234A2 (en) * 2004-05-12 2005-11-24 Sugen, Inc. Methods of using zc1 and zc3 kinase substrate phosphorylation as biomarkers
EP1848831A4 (de) * 2005-01-13 2008-11-05 Novartis Vaccines & Diagnostic Elisa-tests unter verwendung prionspezifischer peptidreagentien
EP1848830A4 (de) * 2005-01-13 2009-05-06 Novartis Vaccines & Diagnostic Isolierung pathogener prione
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
DK1931695T3 (da) * 2005-09-09 2013-07-01 Novartis Ag Prionspecifikke peptoidreagenser
CA2721982A1 (en) * 2008-04-30 2009-11-05 Novartis Ag Assay for pathogenic conformers
KR101219395B1 (ko) * 2010-07-15 2013-01-11 전자부품연구원 리튬이차전지용 양극재료 및 그의 제조방법

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US4343940A (en) 1979-02-13 1982-08-10 Mead Johnson & Company Anti-tumor quinazoline compounds
EP0031237B1 (de) 1979-12-19 1984-10-17 National Research Development Corporation Chinazolinderivate, Verfahren zu ihrer Herstellung, sie enthaltende Zusammensetzungen und ihre Verwendung als Anti-Krebs-Mittel
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
DE3611194A1 (de) 1986-04-04 1987-10-08 Bayer Ag Cancerostatisches mittel
US5217999A (en) 1987-12-24 1993-06-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Styryl compounds which inhibit EGF receptor protein tyrosine kinase
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US5302606A (en) 1990-04-16 1994-04-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase
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AU4448597A (en) 1996-10-04 1998-05-05 Connaught Laboratories Limited Treatment of cancer using a recombinant poxvirus containing nucleic acid sequence encoding a cytokine
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WO1999007854A2 (en) * 1997-08-11 1999-02-18 Ontogeny, Inc. Serine/threonine kinase, and uses related thereto
GB9719920D0 (en) * 1997-09-19 1997-11-19 Zeneca Ltd Human Ste20-Like Stress Activated Serine/Threonine Kinase
GB9726851D0 (en) * 1997-12-19 1998-02-18 Zeneca Ltd Human signal transduction serine/threonine kinase
US6013500A (en) * 1998-05-21 2000-01-11 The Trustees Of Columbia University In The City Of New York PAK4, a novel gene encoding a serine/threonine kinase

Also Published As

Publication number Publication date
DK1073723T3 (da) 2006-01-02
WO1999053036A9 (en) 2000-02-17
DE69926742D1 (de) 2005-09-22
JP2002522009A (ja) 2002-07-23
ES2248997T3 (es) 2006-03-16
US20030050230A1 (en) 2003-03-13
US6656716B1 (en) 2003-12-02
WO1999053036A3 (en) 2000-05-11
EP1073723A2 (de) 2001-02-07
WO1999053036A2 (en) 1999-10-21
EP1073723B1 (de) 2005-08-17
US20050142625A1 (en) 2005-06-30
US20070072261A1 (en) 2007-03-29
AU3642499A (en) 1999-11-01
CA2369172A1 (en) 1999-10-21
DE69926742T2 (de) 2006-06-14
US6680170B2 (en) 2004-01-20
US20040224323A1 (en) 2004-11-11

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