UA39920C2 - Аналоги 15-дезоксиспергуаліну або їх солі, що мають імуносупресивну активність, спосіб їх отримання та фармацевтична композиція на їх основі - Google Patents

Аналоги 15-дезоксиспергуаліну або їх солі, що мають імуносупресивну активність, спосіб їх отримання та фармацевтична композиція на їх основі

Info

Publication number
UA39920C2
UA39920C2 UA93003726A UA93003726A UA39920C2 UA 39920 C2 UA39920 C2 UA 39920C2 UA 93003726 A UA93003726 A UA 93003726A UA 93003726 A UA93003726 A UA 93003726A UA 39920 C2 UA39920 C2 UA 39920C2
Authority
UA
Ukraine
Prior art keywords
composition
deoxyspergualin
analogues
salts
obtaining
Prior art date
Application number
UA93003726A
Other languages
English (en)
Ukrainian (uk)
Inventor
Патріс РЕНО
Патрис РЕНО
Патрік ДЮТАРТР
Люк Лебретон
Філіпп ДЕРРЕПА
Сот САМРЕТ
Original Assignee
Фурньє Ендюстрі Е Санте
Фурнье Эндюстри Э Санте
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фурньє Ендюстрі Е Санте, Фурнье Эндюстри Э Санте filed Critical Фурньє Ендюстрі Е Санте
Publication of UA39920C2 publication Critical patent/UA39920C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
UA93003726A 1992-12-02 1993-12-01 Аналоги 15-дезоксиспергуаліну або їх солі, що мають імуносупресивну активність, спосіб їх отримання та фармацевтична композиція на їх основі UA39920C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
UA39920C2 true UA39920C2 (uk) 2001-07-16

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
UA93003726A UA39920C2 (uk) 1992-12-02 1993-12-01 Аналоги 15-дезоксиспергуаліну або їх солі, що мають імуносупресивну активність, спосіб їх отримання та фармацевтична композиція на їх основі

Country Status (23)

Country Link
US (1) US5476870A (enExample)
EP (1) EP0600762B1 (enExample)
JP (1) JP2945261B2 (enExample)
KR (1) KR100187328B1 (enExample)
CN (1) CN1045431C (enExample)
AT (1) ATE140215T1 (enExample)
AU (1) AU664124B2 (enExample)
CA (1) CA2110437C (enExample)
CZ (1) CZ284958B6 (enExample)
DE (1) DE69303583T2 (enExample)
DK (1) DK0600762T3 (enExample)
ES (1) ES2092263T3 (enExample)
FI (1) FI112211B (enExample)
FR (1) FR2698628B1 (enExample)
GR (1) GR3021269T3 (enExample)
HU (1) HU218908B (enExample)
NO (1) NO180483C (enExample)
NZ (1) NZ250330A (enExample)
RU (1) RU2114823C1 (enExample)
SK (1) SK280286B6 (enExample)
TW (1) TW311132B (enExample)
UA (1) UA39920C2 (enExample)
ZA (1) ZA938821B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09511765A (ja) * 1995-02-10 1997-11-25 フルニエ・アンデュストリ・エ・サンテ １５−デオキシスペルグアリン類似体、その治療用途及びその調製方法
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
ES2139465T3 (es) * 1996-12-20 2000-02-01 Sueddeutsche Kalkstickstoff Piruvatos de creatina y procedimiento para su preparacion.
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
HK1043801A1 (zh) * 1998-08-28 2002-09-27 格莱风科学公司 精确长度的聚酰胺链、其制备方法和其与蛋白质的缀合物
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
CA2565633C (en) * 2004-05-05 2016-04-26 Atugen Ag Lipids, lipid complexes and use thereof
WO2006069782A2 (en) 2004-12-27 2006-07-06 Silence Therapeutics Ag. Lipid complexes coated with peg and their use
WO2010074591A1 (ru) 2008-12-24 2010-07-01 Закрытое Акционерное Общество "Beptekc" Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
JP5878172B2 (ja) * 2010-07-29 2016-03-08 ラボラトワール フルニエ エスアーエス 炎症性眼疾患の治療／予防用化合物
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
DE3770680D1 (de) * 1986-04-04 1991-07-18 Microbial Chem Res Found Spergualinaehnliche verbindungen und ihr herstellungsverfahren.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
CN1045431C (zh) 1999-10-06
HU218908B (hu) 2000-12-28
FR2698628B1 (fr) 1995-02-17
EP0600762B1 (fr) 1996-07-10
NO180483C (no) 1997-04-30
SK280286B6 (sk) 1999-11-08
TW311132B (enExample) 1997-07-21
RU2114823C1 (ru) 1998-07-10
FI935318A0 (fi) 1993-11-29
DE69303583T2 (de) 1996-11-21
CA2110437A1 (en) 1994-06-03
NO180483B (no) 1997-01-20
JPH06293728A (ja) 1994-10-21
CZ262293A3 (en) 1994-06-15
NO934338L (no) 1994-06-03
CN1095709A (zh) 1994-11-30
NZ250330A (en) 1995-06-27
DE69303583D1 (de) 1996-08-14
US5476870A (en) 1995-12-19
NO934338D0 (no) 1993-11-30
HK1000467A1 (en) 1998-03-27
FR2698628A1 (fr) 1994-06-03
HUT65782A (en) 1994-07-28
FI935318L (fi) 1994-06-03
ATE140215T1 (de) 1996-07-15
CA2110437C (en) 1999-04-13
EP0600762A1 (fr) 1994-06-08
AU5188393A (en) 1994-06-16
HU9303406D0 (en) 1994-03-28
CZ284958B6 (cs) 1999-04-14
JP2945261B2 (ja) 1999-09-06
SK135793A3 (en) 1994-06-08
ZA938821B (en) 1994-06-30
KR940014435A (ko) 1994-07-18
GR3021269T3 (en) 1997-01-31
DK0600762T3 (da) 1996-11-11
KR100187328B1 (ko) 1999-05-15
FI112211B (fi) 2003-11-14
AU664124B2 (en) 1995-11-02
ES2092263T3 (es) 1996-11-16

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