DK484684A - Derivater af 4-alkyl-2-hydroxy-3-methyl-2-phenylmorpholin, fremgangsmaade til deres fremstilling og deres terapeutiske anvendelse - Google Patents
Derivater af 4-alkyl-2-hydroxy-3-methyl-2-phenylmorpholin, fremgangsmaade til deres fremstilling og deres terapeutiske anvendelse Download PDFInfo
- Publication number
- DK484684A DK484684A DK484684A DK484684A DK484684A DK 484684 A DK484684 A DK 484684A DK 484684 A DK484684 A DK 484684A DK 484684 A DK484684 A DK 484684A DK 484684 A DK484684 A DK 484684A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- hydroxy
- methyl
- phenylmorpholine
- derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 229960003209 phenmetrazine Drugs 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000021 stimulant Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8316485 | 1983-10-17 | ||
| FR8316485A FR2553413B1 (fr) | 1983-10-17 | 1983-10-17 | Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK484684D0 DK484684D0 (da) | 1984-10-10 |
| DK484684A true DK484684A (da) | 1985-04-18 |
| DK157682B DK157682B (da) | 1990-02-05 |
| DK157682C DK157682C (da) | 1990-07-09 |
Family
ID=9293216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK484684A DK157682C (da) | 1983-10-17 | 1984-10-10 | 4-ethyl-2-hydroxy-3-methyl-2-phenylmorpholin og additionssalte deraf samt terapeutisk middel |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4576944A (da) |
| EP (1) | EP0139590B1 (da) |
| JP (1) | JPS6097969A (da) |
| AT (1) | ATE35261T1 (da) |
| AU (1) | AU565778B2 (da) |
| CA (1) | CA1228354A (da) |
| DE (1) | DE3472256D1 (da) |
| DK (1) | DK157682C (da) |
| ES (1) | ES536991A0 (da) |
| FR (1) | FR2553413B1 (da) |
| GR (1) | GR80658B (da) |
| IE (1) | IE57773B1 (da) |
| ZA (1) | ZA848024B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8417170D0 (en) * | 1984-07-05 | 1984-08-08 | Wellcome Found | Heterocyclic pharmaceutical compounds |
| GB8924528D0 (en) * | 1989-10-31 | 1989-12-20 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
| GB9108629D0 (en) * | 1991-04-23 | 1991-06-12 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
| RU2408368C2 (ru) | 2005-06-27 | 2011-01-10 | Биовэйл Лэборэториз Интернэшнл С.Р.Л. | Препараты соли бупропиона с модифицированным высвобождением |
| CA2800219C (en) | 2010-05-21 | 2019-03-12 | Research Triangle Institute | 1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence |
| EP2571858B1 (en) | 2010-05-21 | 2018-06-20 | Research Triangle Institute | Phenylmorpholines and analogues thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB791416A (en) * | 1956-04-09 | 1958-03-05 | Albert Boehringer | Improvements in or relating to the production of substituted tetrahydrooxazines |
| US3117967A (en) * | 1962-04-02 | 1964-01-14 | Smith Kline French Lab | 2-biphenylyl-2-hydroxy-morpholinium halides |
| US3225042A (en) * | 1962-07-31 | 1965-12-21 | Lilly Co Eli | Hydroxymorpholines |
| US4044131A (en) * | 1975-11-24 | 1977-08-23 | American Home Products Corporation | 2-Morpholinol derivatives |
-
1983
- 1983-10-17 FR FR8316485A patent/FR2553413B1/fr not_active Expired
-
1984
- 1984-10-04 CA CA000464758A patent/CA1228354A/fr not_active Expired
- 1984-10-05 IE IE2552/84A patent/IE57773B1/en not_active IP Right Cessation
- 1984-10-10 AU AU34091/84A patent/AU565778B2/en not_active Ceased
- 1984-10-10 DK DK484684A patent/DK157682C/da active
- 1984-10-12 AT AT84402065T patent/ATE35261T1/de not_active IP Right Cessation
- 1984-10-12 US US06/660,218 patent/US4576944A/en not_active Expired - Fee Related
- 1984-10-12 EP EP84402065A patent/EP0139590B1/fr not_active Expired
- 1984-10-12 DE DE8484402065T patent/DE3472256D1/de not_active Expired
- 1984-10-15 GR GR80658A patent/GR80658B/el unknown
- 1984-10-15 ZA ZA848024A patent/ZA848024B/xx unknown
- 1984-10-15 JP JP59217208A patent/JPS6097969A/ja active Granted
- 1984-10-16 ES ES536991A patent/ES536991A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8507123A1 (es) | 1985-08-16 |
| EP0139590B1 (fr) | 1988-06-22 |
| DK157682B (da) | 1990-02-05 |
| AU565778B2 (en) | 1987-09-24 |
| DE3472256D1 (en) | 1988-07-28 |
| AU3409184A (en) | 1985-04-26 |
| JPS6097969A (ja) | 1985-05-31 |
| CA1228354A (fr) | 1987-10-20 |
| GR80658B (en) | 1985-02-18 |
| IE57773B1 (en) | 1993-04-07 |
| DK484684D0 (da) | 1984-10-10 |
| FR2553413A1 (fr) | 1985-04-19 |
| EP0139590A3 (en) | 1985-06-26 |
| ZA848024B (en) | 1985-06-26 |
| EP0139590A2 (fr) | 1985-05-02 |
| DK157682C (da) | 1990-07-09 |
| ATE35261T1 (de) | 1988-07-15 |
| FR2553413B1 (fr) | 1986-03-21 |
| JPH0522704B2 (da) | 1993-03-30 |
| IE842552L (en) | 1985-04-17 |
| ES536991A0 (es) | 1985-08-16 |
| US4576944A (en) | 1986-03-18 |
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