DK0596802T3 - Erythromycinderivater, deres fremstilling og deres anvendelse som lægemidler - Google Patents

Erythromycinderivater, deres fremstilling og deres anvendelse som lægemidler

Info

Publication number
DK0596802T3
DK0596802T3 DK93402704.6T DK93402704T DK0596802T3 DK 0596802 T3 DK0596802 T3 DK 0596802T3 DK 93402704 T DK93402704 T DK 93402704T DK 0596802 T3 DK0596802 T3 DK 0596802T3
Authority
DK
Denmark
Prior art keywords
radical
representing
drugs
preparation
compounds
Prior art date
Application number
DK93402704.6T
Other languages
English (en)
Inventor
Martret Odile Le
Jean-Francois Chantot
Constantin Agouridas
Alain Bonnefoy
Alexis Denis
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9213320A external-priority patent/FR2697523B1/fr
Priority claimed from FR9308109A external-priority patent/FR2707088B1/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of DK0596802T3 publication Critical patent/DK0596802T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93402704.6T 1992-11-05 1993-11-04 Erythromycinderivater, deres fremstilling og deres anvendelse som lægemidler DK0596802T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9213320A FR2697523B1 (fr) 1992-11-05 1992-11-05 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR9308109A FR2707088B1 (fr) 1993-07-02 1993-07-02 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (1)

Publication Number Publication Date
DK0596802T3 true DK0596802T3 (da) 1996-06-03

Family

ID=26229842

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93402704.6T DK0596802T3 (da) 1992-11-05 1993-11-04 Erythromycinderivater, deres fremstilling og deres anvendelse som lægemidler

Country Status (16)

Country Link
US (2) US5527780A (da)
EP (1) EP0596802B1 (da)
JP (2) JP3000022B2 (da)
KR (1) KR100317149B1 (da)
CN (1) CN1040876C (da)
AT (1) ATE135706T1 (da)
AU (1) AU670329B2 (da)
BR (1) BR9304481A (da)
CA (1) CA2102457C (da)
DE (1) DE69301897T2 (da)
DK (1) DK0596802T3 (da)
ES (1) ES2085130T3 (da)
GR (1) GR3019385T3 (da)
HU (3) HU220048B (da)
MA (1) MA23018A1 (da)
RU (1) RU2126416C1 (da)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) * 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5747466A (en) * 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
KR100523679B1 (ko) * 1996-09-04 2005-10-26 아보트 러보러터리즈 항균 활성을 지닌 6-ｏ-치환된 케톨라이드
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
JP2000513026A (ja) * 1997-06-11 2000-10-03 ファイザー・プロダクツ・インク ９−オキシム エリスロマイシン誘導体
US5780604A (en) * 1997-09-26 1998-07-14 Abbott Laboratories 11,12-cyclic phosphite or phosphate derivatives of erythromycin and related macrolides
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives
AU9649698A (en) * 1997-10-29 1999-05-17 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
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JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
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FR2785612A1 (fr) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4043191B2 (ja) * 1998-11-03 2008-02-06 ファイザー・プロダクツ・インク 新規なマクロライド抗生物質
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
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HUP0105190A3 (en) 1999-01-27 2003-03-28 Pfizer Prod Inc Ketolide antibiotics, medicaments containing them and their use
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
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CN108310000A (zh) 2009-09-10 2018-07-24 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
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RU2608390C2 (ru) 2010-05-20 2017-01-18 Семпра Фармасьютикалз, Инк. Способы получения макролидов и кетолидов, и промежуточных соединений для их получения
KR20130120458A (ko) * 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
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Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
DE2936865A1 (de) * 1979-09-12 1981-04-02 Bayer Ag, 5090 Leverkusen Verwendung von pikromycin-derivaten als nutritiva
JPS6229595A (ja) * 1985-07-31 1987-02-07 Toyo Jozo Co Ltd ５−ｏ−マイカミノシル−ナルボノライド誘導体およびその製法
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
WO1992009614A1 (fr) * 1990-11-28 1992-06-11 Taisho Pharmaceutical Co., Ltd. Derive de 6-o-methylerythromycine a
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
JPH06220082A (ja) 1994-08-09
US5614614A (en) 1997-03-25
BR9304481A (pt) 1994-06-21
JPH11180994A (ja) 1999-07-06
RU2126416C1 (ru) 1999-02-20
EP0596802B1 (fr) 1996-03-20
CN1090581A (zh) 1994-08-10
CA2102457A1 (fr) 1994-05-06
JP3000022B2 (ja) 2000-01-17
HU221978B1 (hu) 2003-03-28
MA23018A1 (fr) 1994-07-01
ATE135706T1 (de) 1996-04-15
EP0596802A1 (fr) 1994-05-11
HU0003975D0 (da) 2000-12-28
KR100317149B1 (ko) 2002-06-20
AU5047793A (en) 1994-05-19
GR3019385T3 (en) 1996-06-30
KR940011474A (ko) 1994-06-21
HU222113B1 (hu) 2003-04-28
ES2085130T3 (es) 1996-05-16
DE69301897T2 (de) 1996-11-07
CN1040876C (zh) 1998-11-25
JP3151188B2 (ja) 2001-04-03
CA2102457C (fr) 2002-01-22
HU220048B (hu) 2001-10-28
AU670329B2 (en) 1996-07-11
DE69301897D1 (de) 1996-04-25
HUT66446A (en) 1994-11-28
US5527780A (en) 1996-06-18

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