FI101376B1 - Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistamiseksi - Google Patents
Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistamiseksiInfo
- Publication number
- FI101376B1 FI101376B1 FI925415A FI925415A FI101376B1 FI 101376 B1 FI101376 B1 FI 101376B1 FI 925415 A FI925415 A FI 925415A FI 925415 A FI925415 A FI 925415A FI 101376 B1 FI101376 B1 FI 101376B1
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- benzylamino
- phenylpiperidine derivatives
- processes
- phenylpiperidine
- Prior art date
Links
- GTEURKRBYDHVCE-UHFFFAOYSA-N n-benzyl-2-phenylpiperidin-3-amine Chemical class C=1C=CC=CC=1CNC1CCCNC1C1=CC=CC=C1 GTEURKRBYDHVCE-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53126590A | 1990-05-31 | 1990-05-31 | |
| US53126590 | 1990-05-31 | ||
| PCT/US1991/002541 WO1991018878A1 (en) | 1990-05-31 | 1991-04-12 | Preparation of substituted piperidines |
| US9102541 | 1991-04-12 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI925415L FI925415L (fi) | 1992-11-27 |
| FI925415A0 FI925415A0 (fi) | 1992-11-27 |
| FI101376B1 true FI101376B1 (fi) | 1998-06-15 |
| FI101376B FI101376B (fi) | 1998-06-15 |
Family
ID=24116944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI925415A FI101376B (fi) | 1990-05-31 | 1992-11-27 | Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistam iseksi |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0532515B1 (fi) |
| JP (2) | JPH0794439B2 (fi) |
| KR (1) | KR0160142B1 (fi) |
| CN (2) | CN1037768C (fi) |
| AT (1) | ATE144498T1 (fi) |
| AU (1) | AU648558B2 (fi) |
| BR (1) | BR9106518A (fi) |
| CA (1) | CA2080249C (fi) |
| CZ (1) | CZ284663B6 (fi) |
| DE (1) | DE69122866T2 (fi) |
| DK (1) | DK0532515T3 (fi) |
| ES (1) | ES2093099T3 (fi) |
| FI (1) | FI101376B (fi) |
| GR (1) | GR3022079T3 (fi) |
| HU (1) | HU226529B1 (fi) |
| IE (1) | IE911841A1 (fi) |
| IL (3) | IL113011A (fi) |
| MY (1) | MY107819A (fi) |
| NO (1) | NO180083C (fi) |
| NZ (2) | NZ250217A (fi) |
| PL (2) | PL169187B1 (fi) |
| PT (1) | PT97796B (fi) |
| RU (1) | RU2077531C1 (fi) |
| WO (1) | WO1991018878A1 (fi) |
| YU (1) | YU48030B (fi) |
| ZA (1) | ZA914133B (fi) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5332817A (en) * | 1990-01-04 | 1994-07-26 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles |
| UA41251C2 (uk) * | 1990-01-04 | 2001-09-17 | Пфайзер, Інк. | Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі |
| US5364943A (en) * | 1991-11-27 | 1994-11-15 | Pfizer Inc. | Preparation of substituted piperidines |
| BR9205807A (pt) * | 1991-03-26 | 1994-06-28 | Pfizer | Preparação estéreo-seletiva de piperidinas substituidas |
| MY110227A (en) * | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| FI942187L (fi) * | 1991-11-12 | 1994-05-11 | Pfizer | Asyklisiä etyleenidiamiinijohdannaisia aine P-reseptoriantagonisteina |
| CA2150123C (en) * | 1992-12-10 | 2004-12-07 | Harry R. Howard | Aminomethylene substituted non-aromatic heterocycles |
| ES2105664T3 (es) | 1993-05-28 | 1997-10-16 | Pfizer | Procedimiento para la preparacion y resolucion de 2-fenil-3-aminopiperidina. |
| TW397825B (en) * | 1994-10-14 | 2000-07-11 | Novartis Ag | Aroyl-piperidine derivatives |
| FR2728165A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene |
| FR2728169A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales |
| FR2728166A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Composition topique contenant un antagoniste de substance p |
| FR2741262B1 (fr) | 1995-11-20 | 1999-03-05 | Oreal | Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene |
| EP0991622A1 (en) | 1997-06-27 | 2000-04-12 | MERCK SHARP & DOHME LTD. | Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents |
| IL140750A0 (en) * | 1998-07-21 | 2002-02-10 | Syngenta Participations Ag | 3-substituted pyridine compounds and related synthesis |
| CN1131212C (zh) * | 1999-02-24 | 2003-12-17 | 弗·哈夫曼-拉罗切有限公司 | 苯基－和吡啶基衍生物 |
| CN1134417C (zh) * | 1999-02-24 | 2004-01-14 | 弗·哈夫曼-拉罗切有限公司 | 3-苯基吡啶衍生物及其作为nk-1受体拮抗剂的应用 |
| RS49964B (sr) * | 1999-05-17 | 2008-09-29 | Pfizer Products Inc., | Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli |
| TWI259180B (en) * | 2000-08-08 | 2006-08-01 | Hoffmann La Roche | 4-Phenyl-pyridine derivatives |
| JP2011016751A (ja) * | 2009-07-08 | 2011-01-27 | Sumitomo Chemical Co Ltd | 光学活性３−アミノピペリジン−１−カルボキシレート化合物の製造方法およびその製造方法に用いられる中間体 |
| CN111808017B (zh) * | 2020-08-05 | 2023-11-28 | 国家纳米科学中心 | 一种含氮杂环化合物及其制备方法和应用 |
| CN116162055B (zh) * | 2023-03-10 | 2023-09-12 | 山东汇智药物研究有限公司 | 一种用n-氧化吡啶衍生物制备哌啶衍生物的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52125170A (en) * | 1976-04-12 | 1977-10-20 | Yoshitomi Pharmaceut Ind Ltd | Pyridine derivatives |
| CA1160229A (en) * | 1979-03-13 | 1984-01-10 | Pieter T. Haken | Pyridyliminomethylbenzene derivatives |
| GB2056974B (en) * | 1979-07-19 | 1984-02-29 | Shell Int Research | Heterocyclic acylamino compounds having fungicidal herbicidal and plant-growth regulating properties |
| CA1231710A (en) * | 1979-07-19 | 1988-01-19 | Haken Pieter Ten | Heterocyclic compounds having fungicidal, herbicidal and plant-growth regulating properties |
| EP0100158A3 (en) * | 1982-07-28 | 1985-03-27 | The Upjohn Company | (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters |
| US4552960A (en) * | 1983-06-20 | 1985-11-12 | Eli Lilly And Company | Fungicidal amines |
| FR2662696A2 (fr) * | 1989-12-13 | 1991-12-06 | Rhone Poulenc Sante | Antagonistes de la serotonine, leur preparation et medicaments les contenant. |
| UA41251C2 (uk) * | 1990-01-04 | 2001-09-17 | Пфайзер, Інк. | Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі |
-
1991
- 1991-04-12 PL PL91309053A patent/PL169187B1/pl unknown
- 1991-04-12 HU HU9203761A patent/HU226529B1/hu not_active IP Right Cessation
- 1991-04-12 AT AT91908255T patent/ATE144498T1/de not_active IP Right Cessation
- 1991-04-12 ES ES91908255T patent/ES2093099T3/es not_active Expired - Lifetime
- 1991-04-12 WO PCT/US1991/002541 patent/WO1991018878A1/en not_active Ceased
- 1991-04-12 AU AU77703/91A patent/AU648558B2/en not_active Ceased
- 1991-04-12 PL PL91297179A patent/PL168236B1/pl unknown
- 1991-04-12 RU RU9192016444A patent/RU2077531C1/ru not_active IP Right Cessation
- 1991-04-12 JP JP3508366A patent/JPH0794439B2/ja not_active Expired - Fee Related
- 1991-04-12 CA CA002080249A patent/CA2080249C/en not_active Expired - Fee Related
- 1991-04-12 EP EP91908255A patent/EP0532515B1/en not_active Expired - Lifetime
- 1991-04-12 KR KR1019920703014A patent/KR0160142B1/ko not_active Expired - Fee Related
- 1991-04-12 DK DK91908255.2T patent/DK0532515T3/da active
- 1991-04-12 DE DE69122866T patent/DE69122866T2/de not_active Expired - Fee Related
- 1991-04-12 BR BR919106518A patent/BR9106518A/pt not_active Application Discontinuation
- 1991-05-24 IL IL11301191A patent/IL113011A/xx not_active IP Right Cessation
- 1991-05-24 IL IL9825691A patent/IL98256A/en not_active IP Right Cessation
- 1991-05-29 MY MYPI91000939A patent/MY107819A/en unknown
- 1991-05-29 PT PT97796A patent/PT97796B/pt not_active IP Right Cessation
- 1991-05-30 NZ NZ250217A patent/NZ250217A/en unknown
- 1991-05-30 CN CN91103654A patent/CN1037768C/zh not_active Expired - Fee Related
- 1991-05-30 IE IE184191A patent/IE911841A1/en not_active IP Right Cessation
- 1991-05-30 CZ CS911623A patent/CZ284663B6/cs not_active IP Right Cessation
- 1991-05-30 NZ NZ238340A patent/NZ238340A/xx unknown
- 1991-05-30 YU YU96291A patent/YU48030B/sh unknown
- 1991-05-30 ZA ZA914133A patent/ZA914133B/xx unknown
-
1992
- 1992-11-27 FI FI925415A patent/FI101376B/fi active
- 1992-11-27 NO NO924598A patent/NO180083C/no not_active IP Right Cessation
-
1994
- 1994-12-26 JP JP6322305A patent/JP2549609B2/ja not_active Expired - Fee Related
-
1995
- 1995-03-16 IL IL11301195A patent/IL113011A0/xx unknown
-
1996
- 1996-12-18 GR GR960403524T patent/GR3022079T3/el unknown
-
1997
- 1997-08-26 CN CNB971178879A patent/CN1154636C/zh not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI101376B1 (fi) | Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistamiseksi | |
| HUT68963A (en) | Novel 4-arylpiperazines and 4-arylpiperidines, pharmaceutical compositions comprising them and the proces for producing thereof | |
| FI933903A0 (fi) | Substituerade cyklohexanderivat, foerfarande foer framstaellning daerav och anvaendning av foereningar foer behandling av sjukdomar | |
| NO941958D0 (no) | Fremstilling av substituerte piperidiner | |
| DK0393424T3 (da) | Fremgangsmåde til fremstilling af 2,7-diazabicyclo(3.3.0)octaner | |
| DK0450420T3 (da) | Heterocyclisk substituerede dihydropyridiner, fremgangsmåde til deres fremstilling og deres anvendelse i lægemidler | |
| ATE51617T1 (de) | Verfahren zur herstellung von 4-phenyl-pyrrolderivaten. | |
| GR3023757T3 (en) | Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents. | |
| FI915875L (fi) | Menetelmä yleisen kaavan I mukaisten lääkeaineina käyttökelpoisten 2,3-dihydro-4H-1,3-bentsoksatsinon-4-onien ja 2,3-dihydro-4H-bentsotiatsinon-4-onien nitro-oksijohdannaisten valmistamiseksi | |
| PH24207A (en) | 2-acylamino-6-amino-4,5,6,7-tetrahydrobenzothiazoles | |
| HUT54682A (en) | Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds | |
| DK0521766T3 (da) | Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater | |
| HUT57746A (en) | Process for producing new 1,3-oxazines and pharmaceutical compositions comprising same | |
| NO980937D0 (no) | Fremgangsmåte for fremstilling av benzyl-substituerte rhodaninderivater | |
| FI944967L (fi) | Menetelmiä proteolyyttisen entsyymin inhibiittoreina käyttökelpoisten sakkariinijohdannaisten ja niiden välituotteiden valmistamiseksi |