DK0582368T3 - Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet - Google Patents
Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemetInfo
- Publication number
- DK0582368T3 DK0582368T3 DK93304102T DK93304102T DK0582368T3 DK 0582368 T3 DK0582368 T3 DK 0582368T3 DK 93304102 T DK93304102 T DK 93304102T DK 93304102 T DK93304102 T DK 93304102T DK 0582368 T3 DK0582368 T3 DK 0582368T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- nervous system
- central nervous
- system disorders
- alkyl
- Prior art date
Links
- 208000015114 central nervous system disease Diseases 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929211379A GB9211379D0 (en) | 1992-05-29 | 1992-05-29 | Pharmaceutical compounds |
| GB939309025A GB9309025D0 (en) | 1993-04-30 | 1993-04-30 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0582368T3 true DK0582368T3 (da) | 2001-02-05 |
Family
ID=26300951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93304102T DK0582368T3 (da) | 1992-05-29 | 1993-05-26 | Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0582368B1 (https=) |
| JP (1) | JP3219541B2 (https=) |
| CN (1) | CN1043994C (https=) |
| AT (1) | ATE198891T1 (https=) |
| AU (1) | AU668159B2 (https=) |
| CA (1) | CA2097016A1 (https=) |
| CZ (1) | CZ282783B6 (https=) |
| DE (1) | DE69329887T2 (https=) |
| DK (1) | DK0582368T3 (https=) |
| ES (1) | ES2153373T3 (https=) |
| FI (1) | FI101538B (https=) |
| GR (1) | GR3035587T3 (https=) |
| HU (1) | HU218278B (https=) |
| IL (1) | IL105827A (https=) |
| MX (1) | MX9303124A (https=) |
| MY (1) | MY109943A (https=) |
| NO (1) | NO305125B1 (https=) |
| NZ (1) | NZ247703A (https=) |
| PT (1) | PT582368E (https=) |
| RU (1) | RU2125574C1 (https=) |
| TW (1) | TW268005B (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5457101A (en) * | 1994-06-03 | 1995-10-10 | Eli Lilly And Company | Thieno[1,5]benzoidiazepine use |
| US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
| EG24221A (en) * | 1995-03-24 | 2008-11-10 | Lilly Co Eli | Process for preparing olanzapine |
| EG23659A (en) * | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| CR5278A (es) | 1995-03-24 | 1996-07-04 | Lilly Co Eli | Formulacion oral de 2-metil-tieno-benzodiacepina |
| US5891461A (en) * | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
| CZ298398A3 (cs) * | 1996-03-25 | 1999-06-16 | Eli Lilly And Company | Farmaceutický přípravek |
| PL329217A1 (en) * | 1996-03-25 | 1999-03-15 | Lilly Co Eli | Pain relieving method |
| WO1997035586A1 (en) * | 1996-03-25 | 1997-10-02 | Eli Lilly And Company | Method for treating pain |
| ZA978515B (en) * | 1996-09-23 | 1999-03-23 | Lilly Co Eli | Intermediates and process for preparing olanzapine |
| CZ299247B6 (cs) * | 1996-09-23 | 2008-05-28 | Eli Lilly And Company | Olanzapin dihydrát D |
| ID21762A (id) * | 1996-09-24 | 1999-07-22 | Lilly Co Eli | Formulasi partikel bersaput |
| RU2185383C1 (ru) * | 2001-05-22 | 2002-07-20 | Институт молекулярной генетики РАН | ВЫСОКОМЕЧЕННЫЙ ТРИТИЕМ 2-МЕТИЛ-4-(4-МЕТИЛ-1-ПИПЕРАЗИНИЛ)-10Н-ТИЕНО[2,3-b][1,5]БЕНЗОДИАЗЕПИН |
| TR201816378T4 (tr) * | 2012-08-21 | 2018-11-21 | Janssen Pharmaceutica Nv | Olanzapin haptenleri. |
| ES2654413T3 (es) | 2012-08-21 | 2018-02-13 | Janssen Pharmaceutica, N.V. | Anticuerpos a quetiapina y uso de los mismos |
| ES2904838T3 (es) | 2012-08-21 | 2022-04-06 | Janssen Pharmaceutica Nv | Haptenos de risperidona y paliperidona |
| ES2978909T3 (es) | 2012-08-21 | 2024-09-23 | Janssen Pharmaceutica Nv | Anticuerpos contra haptenos de aripiprazol y uso de los mismos |
| CA2882562C (en) | 2012-08-21 | 2019-08-27 | Eric Hryhorenko | Antibodies to aripiprazole and use thereof |
| US9494608B2 (en) | 2012-08-21 | 2016-11-15 | Janssen Pharmaceutica Nv | Antibodies to olanzapine and use thereof |
| ES2822907T3 (es) | 2012-08-21 | 2021-05-05 | Janssen Pharmaceutica Nv | Haptenos de quetiapina para su uso en inmunoensayos |
| CN104736565B (zh) | 2012-08-21 | 2019-03-12 | 詹森药业有限公司 | 利培酮半抗原的抗体及其用途 |
| JP2015529199A (ja) | 2012-08-21 | 2015-10-05 | オルソ−クリニカル ダイアグノスティクス，インコーポレイティド | パリペリドンハプテンに対する抗体及びその使用 |
| AU2013305930B2 (en) | 2012-08-21 | 2017-08-24 | Saladax Biomedical Inc. | Haptens of paliperidone |
| JP6389177B2 (ja) | 2012-08-21 | 2018-09-12 | ヤンセン ファーマシューティカ エヌ．ベー． | オランザピンハプテンに対する抗体及びその使用 |
| CA2882490A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone and use thereof |
| ES2652641T3 (es) | 2012-08-21 | 2018-02-05 | Janssen Pharmaceutica Nv | Haptenos de aripiprazol y su uso en inmunoensayos |
| ES2788716T3 (es) | 2012-08-21 | 2020-10-22 | Janssen Pharmaceutica Nv | Anticuerpos para haptenos de quetiapina y uso de los mismos |
| EP3462173B1 (en) | 2012-08-21 | 2021-03-31 | Janssen Pharmaceutica NV | Antibodies to risperidone and use thereof |
| CN108431040B (zh) | 2015-12-17 | 2022-07-26 | 詹森药业有限公司 | 利培酮的抗体及其用途 |
| EP3390455A1 (en) | 2015-12-17 | 2018-10-24 | Janssen Pharmaceutica NV | Antibodies to quetiapine and use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962248A (en) * | 1972-04-04 | 1976-06-08 | Sandoz, Inc. | Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines |
| CH569730A5 (https=) * | 1972-04-04 | 1975-11-28 | Wander Ag Dr A | |
| SU629879A3 (ru) * | 1974-11-26 | 1978-10-25 | Лилли Индастриз Лимитед, (Фирма) | Способ получени тиено(1,5) бензодиазепинов или их солей |
| US4061752A (en) * | 1975-08-06 | 1977-12-06 | Sandoz Ltd. | 6-Piperazino-11-methylene-dibenzazepines[b,e] |
| FI762646A7 (https=) * | 1975-09-24 | 1977-03-25 | Sandoz Ag | |
| CH624682A5 (https=) * | 1976-11-10 | 1981-08-14 | Sandoz Ag | |
| US4761411A (en) * | 1983-05-18 | 1988-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses |
| GB9009229D0 (en) * | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1993
- 1993-05-26 DK DK93304102T patent/DK0582368T3/da active
- 1993-05-26 AU AU39807/93A patent/AU668159B2/en not_active Ceased
- 1993-05-26 NZ NZ247703A patent/NZ247703A/en unknown
- 1993-05-26 AT AT93304102T patent/ATE198891T1/de not_active IP Right Cessation
- 1993-05-26 TW TW082104161A patent/TW268005B/zh active
- 1993-05-26 PT PT93304102T patent/PT582368E/pt unknown
- 1993-05-26 EP EP93304102A patent/EP0582368B1/en not_active Expired - Lifetime
- 1993-05-26 ES ES93304102T patent/ES2153373T3/es not_active Expired - Lifetime
- 1993-05-26 NO NO931917A patent/NO305125B1/no not_active IP Right Cessation
- 1993-05-26 DE DE69329887T patent/DE69329887T2/de not_active Expired - Fee Related
- 1993-05-26 CA CA002097016A patent/CA2097016A1/en not_active Abandoned
- 1993-05-27 MX MX9303124A patent/MX9303124A/es not_active IP Right Cessation
- 1993-05-28 FI FI932445A patent/FI101538B/fi active
- 1993-05-28 JP JP12642993A patent/JP3219541B2/ja not_active Expired - Fee Related
- 1993-05-28 IL IL10582793A patent/IL105827A/xx not_active IP Right Cessation
- 1993-05-28 CN CN93108212A patent/CN1043994C/zh not_active Expired - Fee Related
- 1993-05-28 HU HU9301579A patent/HU218278B/hu not_active IP Right Cessation
- 1993-05-28 MY MYPI93001036A patent/MY109943A/en unknown
- 1993-05-28 RU RU93005057A patent/RU2125574C1/ru active
- 1993-05-28 CZ CZ931024A patent/CZ282783B6/cs not_active IP Right Cessation
-
2001
- 2001-03-15 GR GR20010400431T patent/GR3035587T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW268005B (https=) | 1996-01-11 |
| CN1085903A (zh) | 1994-04-27 |
| MY109943A (en) | 1997-10-31 |
| JPH0687862A (ja) | 1994-03-29 |
| FI101538B1 (fi) | 1998-07-15 |
| CZ102493A3 (en) | 1993-12-15 |
| HU9301579D0 (en) | 1993-09-28 |
| FI932445A0 (fi) | 1993-05-28 |
| CA2097016A1 (en) | 1993-11-30 |
| CZ282783B6 (cs) | 1997-10-15 |
| GR3035587T3 (en) | 2001-06-29 |
| CN1043994C (zh) | 1999-07-07 |
| FI101538B (fi) | 1998-07-15 |
| HU218278B (en) | 2000-07-28 |
| DE69329887D1 (de) | 2001-03-01 |
| FI932445L (fi) | 1993-11-30 |
| IL105827A0 (en) | 1993-09-22 |
| JP3219541B2 (ja) | 2001-10-15 |
| AU668159B2 (en) | 1996-04-26 |
| HUT66180A (en) | 1994-09-28 |
| DE69329887T2 (de) | 2001-05-23 |
| AU3980793A (en) | 1993-12-02 |
| IL105827A (en) | 1997-02-18 |
| NO931917D0 (no) | 1993-05-26 |
| RU2125574C1 (ru) | 1999-01-27 |
| NZ247703A (en) | 1995-07-26 |
| MX9303124A (es) | 1993-11-01 |
| ATE198891T1 (de) | 2001-02-15 |
| EP0582368A1 (en) | 1994-02-09 |
| EP0582368B1 (en) | 2001-01-24 |
| NO305125B1 (no) | 1999-04-06 |
| PT582368E (pt) | 2001-05-31 |
| ES2153373T3 (es) | 2001-03-01 |
| NO931917L (no) | 1993-11-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0582368T3 (da) | Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet | |
| DE68914292D1 (de) | Zusammensetzung zur Behandlung von ischämischen Störungen in Organen. | |
| FR2662162B1 (fr) | Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. | |
| ZA897660B (en) | Biologically active compounds | |
| NO821494L (no) | Terapeutisk nyttige 1-alkyl-2-aminotetralinderivater | |
| NO893205L (no) | Kjemiske forbindelser. | |
| MX9202803A (es) | Nuevos compuestos de benzopirano y procedimiento para su preparacion. | |
| MD1560F2 (en) | Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses. | |
| MX9300875A (es) | Procedimiento para la preparacion de compuestos azabiciclicos. | |
| DK0594099T3 (da) | Fremgangsmåde til rensning af rå clavulansyre | |
| ATE264104T1 (de) | Immunmodulierende arzneimittelzusammenstellung | |
| ATE98230T1 (de) | Indolderivate. | |
| ATE186912T1 (de) | Carbamoylpyrrolidon-derivate zur behandlung von depressionen und cerebrovasculären störungen | |
| DE69527854D1 (de) | Derivate substituierter amidinonaphthylester | |
| PT889044E (pt) | Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central | |
| DE3867494D1 (de) | Fluor enthaltende vitamin-d2-derivate. | |
| DK0501442T3 (da) | 8-Chlor-benzothiazepin-forbindelse til forebyggelse og behandling af følgerne af cerebral nekrose af nerveceller | |
| ES2133095A1 (es) | Acidos alquilidenglutaminicos con propiedades farmaceuticas. |