ES2153373T3 - Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central. - Google Patents
Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central.Info
- Publication number
- ES2153373T3 ES2153373T3 ES93304102T ES93304102T ES2153373T3 ES 2153373 T3 ES2153373 T3 ES 2153373T3 ES 93304102 T ES93304102 T ES 93304102T ES 93304102 T ES93304102 T ES 93304102T ES 2153373 T3 ES2153373 T3 ES 2153373T3
- Authority
- ES
- Spain
- Prior art keywords
- tienobenzodiazepin
- disorders
- derivatives
- treatment
- nervous system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE PRESENTAN COMPUESTOS FARMACEUTICOS DE LA FORMULA (I): EN LA QUE R1 ES HIDROGENO O HALO, Y R2 ES ALQUIL C1-C10, ALQUENIL C2-C10, ALQUINIL C2-C10, CICLOALQUIL C3-C6 OPCIONALMENTE SUSTITUIDO CON ENTRE 1 Y 3 GRUPOS DE ALQUIL C1-C4, CICLOALQUIL C3-C6 Y -ALQUIL C1-C4 EN EL QUE EL GRUPO DE CICLOALQUIL ESTA OPCIONALMENTE SUBSTITUIDO POR ENTRE 1 Y 3 GRUPOS DE ALQUIL C1-C4, O FENIL-ALQUIL C1-C4 OPCIONALMENTE SUSTITUIDO O UNA SAL DE LOS MISMOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929211379A GB9211379D0 (en) | 1992-05-29 | 1992-05-29 | Pharmaceutical compounds |
GB939309025A GB9309025D0 (en) | 1993-04-30 | 1993-04-30 | Pharmaceutical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2153373T3 true ES2153373T3 (es) | 2001-03-01 |
Family
ID=26300951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93304102T Expired - Lifetime ES2153373T3 (es) | 1992-05-29 | 1993-05-26 | Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central. |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0582368B1 (es) |
JP (1) | JP3219541B2 (es) |
CN (1) | CN1043994C (es) |
AT (1) | ATE198891T1 (es) |
AU (1) | AU668159B2 (es) |
CA (1) | CA2097016A1 (es) |
CZ (1) | CZ282783B6 (es) |
DE (1) | DE69329887T2 (es) |
DK (1) | DK0582368T3 (es) |
ES (1) | ES2153373T3 (es) |
FI (1) | FI101538B (es) |
GR (1) | GR3035587T3 (es) |
HU (1) | HU218278B (es) |
IL (1) | IL105827A (es) |
MX (1) | MX9303124A (es) |
MY (1) | MY109943A (es) |
NO (1) | NO305125B1 (es) |
NZ (1) | NZ247703A (es) |
PT (1) | PT582368E (es) |
RU (1) | RU2125574C1 (es) |
TW (1) | TW268005B (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5457101A (en) * | 1994-06-03 | 1995-10-10 | Eli Lilly And Company | Thieno[1,5]benzoidiazepine use |
US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
EG23659A (en) * | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
CR5278A (es) | 1995-03-24 | 1996-07-04 | Lilly Co Eli | Formulacion oral de 2-metil-tieno-benzodiacepina |
EG24221A (en) * | 1995-03-24 | 2008-11-10 | Lilly Co Eli | Process for preparing olanzapine |
US5891461A (en) * | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
JP2001508759A (ja) * | 1996-03-25 | 2001-07-03 | イーライ・リリー・アンド・カンパニー | 片頭痛の処置法 |
WO1997035583A1 (en) * | 1996-03-25 | 1997-10-02 | Eli Lilly And Company | Method for treating pain |
PL187926B1 (pl) * | 1996-03-25 | 2004-11-30 | Lilly Co Eli | Kompozycja farmaceutyczna do leczenia bólu |
ZA978515B (en) * | 1996-09-23 | 1999-03-23 | Lilly Co Eli | Intermediates and process for preparing olanzapine |
BR9711541A (pt) | 1996-09-23 | 1999-08-24 | Lilly Co Eli | Dihidrato d de olanzapina |
BR9713215A (pt) * | 1996-09-24 | 2000-04-04 | Lilly Co Eli | Formulação de partìcula revestida |
CN104736561B (zh) | 2012-08-21 | 2018-06-12 | 詹森药业有限公司 | 帕潘立酮的抗体及其用途 |
JP6389176B2 (ja) | 2012-08-21 | 2018-09-12 | ヤンセン ファーマシューティカ エヌ.ベー. | アリピプラゾールハプテンに対する抗体及びその使用 |
US9303041B2 (en) * | 2012-08-21 | 2016-04-05 | Janssen Pharmaceutica Nv | Haptens of olanzapine |
ES2666000T3 (es) | 2012-08-21 | 2018-04-30 | Janssen Pharmaceutica, N.V. | Anticuerpos para aripiprazol y uso de los mismos |
ES2669565T3 (es) | 2012-08-21 | 2018-05-28 | Janssen Pharmaceutica Nv | Haptenos de risperidona y paliperidona |
AU2013305935B2 (en) | 2012-08-21 | 2017-08-24 | Saladax Biomedical Inc. | Haptens of quetiapine for use in immunoassays |
PL2888286T3 (pl) | 2012-08-21 | 2018-07-31 | Janssen Pharmaceutica Nv | Przeciwciała skierowane przeciwko haptenom kwetiapinowym i ich zastosowanie |
CN104736565B (zh) | 2012-08-21 | 2019-03-12 | 詹森药业有限公司 | 利培酮半抗原的抗体及其用途 |
JP6389177B2 (ja) | 2012-08-21 | 2018-09-12 | ヤンセン ファーマシューティカ エヌ.ベー. | オランザピンハプテンに対する抗体及びその使用 |
AU2013305938B2 (en) | 2012-08-21 | 2017-08-17 | Saladax Biomedical Inc. | Antibodies to paliperidone haptens and use thereof |
CN107043424B (zh) | 2012-08-21 | 2021-03-16 | 詹森药业有限公司 | 利培酮的抗体及其用途 |
US9504682B2 (en) | 2012-08-21 | 2016-11-29 | Janssen Pharmaceutica Nv | Haptens of aripiprazole |
EP2888590B1 (en) | 2012-08-21 | 2020-07-08 | Janssen Pharmaceutica NV | Antibodies to olanzapine and use thereof |
PL2888258T3 (pl) | 2012-08-21 | 2019-10-31 | Janssen Pharmaceutica Nv | Hapteny paliperydonu |
CA2882615C (en) | 2012-08-21 | 2019-07-09 | Ortho-Clinical Diagnostics, Inc. | Antibodies to quetiapine and use thereof |
JP6949025B2 (ja) | 2015-12-17 | 2021-10-13 | ヤンセン ファーマシューティカ エヌ.ベー. | リスペリドンに対する抗体及びその使用 |
US10435478B2 (en) | 2015-12-17 | 2019-10-08 | Janssen Pharmaceutica Nv | Antibodies to quetiapine and use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU629879A3 (ru) * | 1974-11-26 | 1978-10-25 | Лилли Индастриз Лимитед, (Фирма) | Способ получени тиено(1,5) бензодиазепинов или их солей |
FI762646A (es) * | 1975-09-24 | 1977-03-25 | Sandoz Ag | |
GB9009229D0 (en) * | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1993
- 1993-05-26 NZ NZ247703A patent/NZ247703A/en unknown
- 1993-05-26 AU AU39807/93A patent/AU668159B2/en not_active Ceased
- 1993-05-26 DE DE69329887T patent/DE69329887T2/de not_active Expired - Fee Related
- 1993-05-26 NO NO931917A patent/NO305125B1/no not_active IP Right Cessation
- 1993-05-26 EP EP93304102A patent/EP0582368B1/en not_active Expired - Lifetime
- 1993-05-26 DK DK93304102T patent/DK0582368T3/da active
- 1993-05-26 AT AT93304102T patent/ATE198891T1/de not_active IP Right Cessation
- 1993-05-26 CA CA002097016A patent/CA2097016A1/en not_active Abandoned
- 1993-05-26 TW TW082104161A patent/TW268005B/zh active
- 1993-05-26 ES ES93304102T patent/ES2153373T3/es not_active Expired - Lifetime
- 1993-05-26 PT PT93304102T patent/PT582368E/pt unknown
- 1993-05-27 MX MX9303124A patent/MX9303124A/es not_active IP Right Cessation
- 1993-05-28 CN CN93108212A patent/CN1043994C/zh not_active Expired - Fee Related
- 1993-05-28 IL IL10582793A patent/IL105827A/xx not_active IP Right Cessation
- 1993-05-28 RU RU93005057A patent/RU2125574C1/ru active
- 1993-05-28 HU HU9301579A patent/HU218278B/hu not_active IP Right Cessation
- 1993-05-28 JP JP12642993A patent/JP3219541B2/ja not_active Expired - Fee Related
- 1993-05-28 CZ CZ931024A patent/CZ282783B6/cs not_active IP Right Cessation
- 1993-05-28 MY MYPI93001036A patent/MY109943A/en unknown
- 1993-05-28 FI FI932445A patent/FI101538B/fi active
-
2001
- 2001-03-15 GR GR20010400431T patent/GR3035587T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI932445A0 (fi) | 1993-05-28 |
EP0582368A1 (en) | 1994-02-09 |
HU9301579D0 (en) | 1993-09-28 |
IL105827A (en) | 1997-02-18 |
CA2097016A1 (en) | 1993-11-30 |
GR3035587T3 (en) | 2001-06-29 |
EP0582368B1 (en) | 2001-01-24 |
DE69329887T2 (de) | 2001-05-23 |
FI101538B1 (fi) | 1998-07-15 |
HU218278B (en) | 2000-07-28 |
AU3980793A (en) | 1993-12-02 |
JP3219541B2 (ja) | 2001-10-15 |
CZ102493A3 (en) | 1993-12-15 |
JPH0687862A (ja) | 1994-03-29 |
IL105827A0 (en) | 1993-09-22 |
MX9303124A (es) | 1993-11-01 |
TW268005B (es) | 1996-01-11 |
DK0582368T3 (da) | 2001-02-05 |
NO931917L (no) | 1993-11-30 |
NZ247703A (en) | 1995-07-26 |
MY109943A (en) | 1997-10-31 |
CN1085903A (zh) | 1994-04-27 |
CZ282783B6 (cs) | 1997-10-15 |
FI101538B (fi) | 1998-07-15 |
NO931917D0 (no) | 1993-05-26 |
CN1043994C (zh) | 1999-07-07 |
DE69329887D1 (de) | 2001-03-01 |
PT582368E (pt) | 2001-05-31 |
NO305125B1 (no) | 1999-04-06 |
FI932445A (fi) | 1993-11-30 |
AU668159B2 (en) | 1996-04-26 |
RU2125574C1 (ru) | 1999-01-27 |
HUT66180A (en) | 1994-09-28 |
ATE198891T1 (de) | 2001-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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