DK0570454T3 - Hidtil ukendte steroider - Google Patents

Hidtil ukendte steroider

Info

Publication number
DK0570454T3
DK0570454T3 DK92904566T DK92904566T DK0570454T3 DK 0570454 T3 DK0570454 T3 DK 0570454T3 DK 92904566 T DK92904566 T DK 92904566T DK 92904566 T DK92904566 T DK 92904566T DK 0570454 T3 DK0570454 T3 DK 0570454T3
Authority
DK
Denmark
Prior art keywords
steroids
hitherto unknown
hitherto
unknown
unknown steroids
Prior art date
Application number
DK92904566T
Other languages
Danish (da)
English (en)
Inventor
Paul Andersson
Bengt Axelsson
Ralph Brattsand
Arne Thalen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of DK0570454T3 publication Critical patent/DK0570454T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92904566T 1991-02-04 1992-01-29 Hidtil ukendte steroider DK0570454T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9100341A SE9100341D0 (sv) 1991-02-04 1991-02-04 Novel steroids
PCT/SE1992/000055 WO1992013872A1 (en) 1991-02-04 1992-01-29 Novel steroids

Publications (1)

Publication Number Publication Date
DK0570454T3 true DK0570454T3 (da) 1999-10-18

Family

ID=20381806

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92904566T DK0570454T3 (da) 1991-02-04 1992-01-29 Hidtil ukendte steroider

Country Status (40)

Country Link
US (2) US5674861A (cs)
EP (1) EP0570454B1 (cs)
JP (1) JPH06505232A (cs)
KR (1) KR100216720B1 (cs)
CN (3) CN1034868C (cs)
AP (1) AP366A (cs)
AT (1) ATE178611T1 (cs)
BG (1) BG62211B1 (cs)
CA (1) CA2103924A1 (cs)
CZ (1) CZ281685B6 (cs)
DE (1) DE69228870T2 (cs)
DK (1) DK0570454T3 (cs)
DZ (1) DZ1553A1 (cs)
EE (1) EE03111B1 (cs)
ES (1) ES2133315T3 (cs)
FI (1) FI933450A0 (cs)
GR (1) GR3030657T3 (cs)
HK (1) HK1010733A1 (cs)
HU (1) HU218275B (cs)
IE (1) IE920166A1 (cs)
IL (1) IL100532A (cs)
IS (1) IS1601B (cs)
MA (1) MA22406A1 (cs)
MX (1) MX9200324A (cs)
NO (1) NO304073B1 (cs)
NZ (1) NZ241210A (cs)
PH (1) PH31284A (cs)
PL (1) PL170000B1 (cs)
PT (1) PT100086B (cs)
RO (1) RO111195B1 (cs)
RU (1) RU2111212C1 (cs)
SE (1) SE9100341D0 (cs)
SG (1) SG52557A1 (cs)
SI (1) SI9210065B (cs)
SK (1) SK281801B6 (cs)
TN (1) TNSN92007A1 (cs)
UA (1) UA41267C2 (cs)
WO (1) WO1992013872A1 (cs)
YU (1) YU48892B (cs)
ZA (1) ZA92233B (cs)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
SK87295A3 (en) * 1993-01-08 1996-04-03 Astra Ab Novel colon or ileum-specific steroid derivatives
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
IT1291288B1 (it) * 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
GB0009607D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medical compositions
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process
JP2005505578A (ja) * 2001-09-25 2005-02-24 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー ステロイドｃ−２２位アセトニドの立体選択的トランスアセタール化
RS20050008A (en) 2002-07-08 2007-06-04 Pliva-Istraživački Institut D.O.O., New compounds,compositions and methods for treatment of inflammatory diseases and conditions
AU2003264917A1 (en) 2002-07-08 2004-01-23 Pliva - Istrazivacki Institut D.O.O. Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
AU2003265576A1 (en) * 2002-08-23 2004-03-11 The Mclean Hospital Corporation Corticosteroid conjugates and uses thereof
TW200417371A (en) * 2003-02-21 2004-09-16 Upjohn Co A continuous process for the production of R-rofleponide
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
CA2585711A1 (en) 2004-10-27 2006-05-04 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugates with anti-inflammatory activity
EP1889198B1 (en) 2005-04-28 2014-11-26 Proteus Digital Health, Inc. Pharma-informatics system
US20080207577A1 (en) * 2005-07-11 2008-08-28 Astrazeneca Ab Combination I
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
WO2008100560A2 (en) * 2007-02-14 2008-08-21 University Of Southern California Estrogen receptor modulators, associated pharmaceutical compositions and methods of use
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378110B (cs) * 1972-05-19 1975-08-18 Bofors Ab
SE378109B (cs) * 1972-05-19 1975-08-18 Bofors Ab
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
CN1060471A (zh) * 1985-04-04 1992-04-22 得拉科公司 新的16，17-缩醛取代雄甾烷-17β-酮类的制备方法
SE8604059D0 (sv) * 1986-09-25 1986-09-25 Astra Pharma Prod A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
HU203562B (en) * 1989-03-09 1991-08-28 Richter Gedeon Vegyeszet Process for producing new steroide diols and pharmaceutical compositions containing them
PL164294B1 (pl) * 1990-12-20 1994-07-29 Inst Farmaceutyczny Sposób otrzymywania diastereoizomeru /22R/-16a , 17a-butylidenodioksy-11 ß 21-dihydroksy-1,4-pregnadien-3,20-dionu PL
SE9100342D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids

Also Published As

Publication number Publication date
RU2111212C1 (ru) 1998-05-20
HU218275B (en) 2000-07-28
WO1992013872A1 (en) 1992-08-20
BG62211B1 (bg) 1999-05-31
HU9302244D0 (en) 1993-10-28
CN1140059A (zh) 1997-01-15
MA22406A1 (fr) 1992-10-01
NO932761D0 (no) 1993-08-02
IL100532A0 (en) 1992-09-06
ES2133315T3 (es) 1999-09-16
HUT64973A (en) 1994-03-28
ATE178611T1 (de) 1999-04-15
BG97971A (bg) 1994-04-29
PL170000B1 (pl) 1996-10-31
CZ281685B6 (cs) 1996-12-11
PT100086A (pt) 1994-05-31
US5939409A (en) 1999-08-17
YU48892B (sh) 2002-10-18
AU661471B2 (en) 1995-07-27
YU6592A (sh) 1995-01-31
CN1058724C (zh) 2000-11-22
EE03111B1 (et) 1998-08-17
ZA92233B (en) 1992-10-28
RO111195B1 (ro) 1996-07-30
IS1601B (is) 1996-10-18
JPH06505232A (ja) 1994-06-16
SE9100341D0 (sv) 1991-02-04
CN1064079A (zh) 1992-09-02
FI933450A (fi) 1993-08-03
CZ149693A3 (en) 1994-03-16
AU1230792A (en) 1992-09-07
DE69228870T2 (de) 1999-08-19
IE920166A1 (en) 1992-08-12
AP366A (en) 1994-10-21
CA2103924A1 (en) 1992-08-05
CN1052155C (zh) 2000-05-10
SG52557A1 (en) 1998-09-28
TNSN92007A1 (fr) 1993-06-08
CN1140178A (zh) 1997-01-15
IS3808A (is) 1992-08-05
HK1010733A1 (en) 1999-06-25
AP9200353A0 (en) 1992-01-31
EP0570454A1 (en) 1993-11-24
NZ241210A (en) 1993-08-26
DE69228870D1 (de) 1999-05-12
IL100532A (en) 1996-05-14
US5674861A (en) 1997-10-07
SK281801B6 (sk) 2001-08-06
NO932761L (no) 1993-08-02
SI9210065A (en) 1995-02-28
SK79693A3 (en) 1994-03-09
DZ1553A1 (fr) 2002-02-17
NO304073B1 (no) 1998-10-19
PH31284A (en) 1998-07-06
KR100216720B1 (ko) 1999-10-01
PT100086B (pt) 1999-06-30
MX9200324A (es) 1992-09-01
CN1034868C (zh) 1997-05-14
GR3030657T3 (en) 1999-10-29
UA41267C2 (uk) 2001-09-17
FI933450A0 (fi) 1993-08-03
EP0570454B1 (en) 1999-04-07
SI9210065B (en) 2001-12-31

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