DK0516410T3 - Hidtil ukendt syntese af 19-nor-vitamin D-forbindelser - Google Patents

Hidtil ukendt syntese af 19-nor-vitamin D-forbindelser

Info

Publication number
DK0516410T3
DK0516410T3 DK92304837T DK92304837T DK0516410T3 DK 0516410 T3 DK0516410 T3 DK 0516410T3 DK 92304837 T DK92304837 T DK 92304837T DK 92304837 T DK92304837 T DK 92304837T DK 0516410 T3 DK0516410 T3 DK 0516410T3
Authority
DK
Denmark
Prior art keywords
vitamin
compounds
synthesis
hitherto unknown
alpha
Prior art date
Application number
DK92304837T
Other languages
Danish (da)
English (en)
Inventor
Hector Floyd Deluca
Heinrich Konstantine Schnoes
Kato Leonard Perlman
Rolf E Swenson
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of DK0516410T3 publication Critical patent/DK0516410T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
    • C07F9/532—Cycloaliphatic phosphine oxides or thioxides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK92304837T 1991-05-28 1992-05-28 Hidtil ukendt syntese af 19-nor-vitamin D-forbindelser DK0516410T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70591791A 1991-05-28 1991-05-28

Publications (1)

Publication Number Publication Date
DK0516410T3 true DK0516410T3 (da) 1998-10-26

Family

ID=24835479

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92304837T DK0516410T3 (da) 1991-05-28 1992-05-28 Hidtil ukendt syntese af 19-nor-vitamin D-forbindelser

Country Status (11)

Country Link
US (7) US5281731A (es)
EP (1) EP0516410B1 (es)
JP (4) JP2648845B2 (es)
KR (3) KR0160784B1 (es)
AT (1) ATE168996T1 (es)
AU (2) AU650751B2 (es)
CA (2) CA2191993C (es)
DE (1) DE69226402T2 (es)
DK (1) DK0516410T3 (es)
ES (1) ES2118794T3 (es)
IE (1) IE921700A1 (es)

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JP4811547B2 (ja) * 2000-10-24 2011-11-09 史衛 佐藤 光学活性シクロヘキセン化合物の製造法及びこの製造に用いる光学活性シクロヘキセン誘導体
US6683219B2 (en) * 2001-07-30 2004-01-27 Wisconsin Alumni Research Foundation Synthesis of A-ring synthon of 19-nor-1α,25-dihydroxyvitamin D3 from (D)-glucose
WO2003026445A1 (en) * 2001-09-27 2003-04-03 The Coca-Cola Company Vitamin fortification of foodstuffs
US6846811B2 (en) * 2002-04-22 2005-01-25 Wisconsin Alumni Research Foundation (20S) 1α-hydroxy-2α-methyl and 2β-methyl-19-nor-vitamin D3 and their uses
US7023347B2 (en) * 2002-08-02 2006-04-04 Symbol Technologies, Inc. Method and system for forming a die frame and for transferring dies therewith
MXPA05009336A (es) 2003-04-10 2005-11-04 Wisconsin Alumni Res Found Compuestos de 2-propiliden-19-nor-vitamina d.
US20050005434A1 (en) * 2003-06-12 2005-01-13 Matrics, Inc. Method, system, and apparatus for high volume transfer of dies
US6894037B2 (en) 2003-07-03 2005-05-17 Wisconsin Alumni Research Foundation 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US7713951B2 (en) 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
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US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
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WO2007105773A1 (ja) 2006-03-15 2007-09-20 Mercian Corporation インデン誘導体の製造方法およびその製造中間体
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US20070244657A1 (en) * 2006-04-11 2007-10-18 Drago Randall A Methods and systems for testing radio frequency identification (RFID) tags having multiple antennas
US20110319644A1 (en) 2006-11-02 2011-12-29 Asako Toyoda Process for production of 1-hydroxy-19-norcyclovitamin d derivative and intermediate for the production
EP2167516B1 (en) 2007-05-30 2015-07-22 Opko IP Holdings II, Inc. Process for producing phosphine oxide vitamin d precursors
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
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CA2639477C (en) * 2008-09-11 2016-03-22 Alphora Research Inc. Paricalcitol purification
US8013176B2 (en) * 2008-09-11 2011-09-06 Alphora Research Inc. Paricalcitol purification
JP5932339B2 (ja) * 2009-01-27 2016-06-08 バーグ エルエルシー 化学療法に付随する副作用を軽減するためのビタミンｄ３およびその類似体
IN2012DN02137A (es) 2009-08-14 2015-08-07 Berg Biosystems Llc
CN101671288B (zh) * 2009-10-14 2013-10-30 兰州大学 帕立骨化醇的中间体的制备方法
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN107501317B (zh) * 2017-09-13 2019-08-16 上海皓元医药股份有限公司 一种帕立骨化醇中间体的制备方法

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Also Published As

Publication number Publication date
JP2926008B2 (ja) 1999-07-28
EP0516410A3 (en) 1993-06-30
JPH05221960A (ja) 1993-08-31
EP0516410A2 (en) 1992-12-02
DE69226402T2 (de) 1998-12-10
AU1712092A (en) 1992-12-03
CA2191993A1 (en) 1992-11-29
KR0160936B1 (ko) 1999-01-15
KR0160937B1 (ko) 1999-01-15
US5486636A (en) 1996-01-23
JPH11240891A (ja) 1999-09-07
JP2002201197A (ja) 2002-07-16
AU650751B2 (en) 1994-06-30
CA2069374A1 (en) 1992-11-29
JP3320025B2 (ja) 2002-09-03
ATE168996T1 (de) 1998-08-15
JP3494637B2 (ja) 2004-02-09
AU659774B2 (en) 1995-05-25
US5563286A (en) 1996-10-08
JPH09118641A (ja) 1997-05-06
KR920021505A (ko) 1992-12-18
EP0516410B1 (en) 1998-07-29
US5616759A (en) 1997-04-01
DE69226402D1 (de) 1998-09-03
JP2648845B2 (ja) 1997-09-03
US5581006A (en) 1996-12-03
US5597932A (en) 1997-01-28
CA2069374C (en) 1999-08-31
ES2118794T3 (es) 1998-10-01
IE921700A1 (en) 1992-12-02
AU5932594A (en) 1994-06-02
US5281731A (en) 1994-01-25
US5391755A (en) 1995-02-21
KR0160784B1 (ko) 1999-01-15
CA2191993C (en) 2002-07-09

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