DE69933131T2 - Zellen zur produktion von helper-abhängigen adenoviren-vektoren - Google Patents

Zellen zur produktion von helper-abhängigen adenoviren-vektoren Download PDF

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Publication number
DE69933131T2
DE69933131T2 DE69933131T DE69933131T DE69933131T2 DE 69933131 T2 DE69933131 T2 DE 69933131T2 DE 69933131 T DE69933131 T DE 69933131T DE 69933131 T DE69933131 T DE 69933131T DE 69933131 T2 DE69933131 T2 DE 69933131T2
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DE
Germany
Prior art keywords
cells
cells according
unit
helper
regions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69933131T
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German (de)
English (en)
Other versions
DE69933131D1 (de
Inventor
Stefano Colloca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application granted granted Critical
Publication of DE69933131D1 publication Critical patent/DE69933131D1/de
Publication of DE69933131T2 publication Critical patent/DE69933131T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69933131T 1998-11-06 1999-11-08 Zellen zur produktion von helper-abhängigen adenoviren-vektoren Expired - Fee Related DE69933131T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM980694 1998-11-06
IT1998RM000694A IT1302403B1 (it) 1998-11-06 1998-11-06 Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso.
PCT/IT1999/000356 WO2000028060A2 (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors

Publications (2)

Publication Number Publication Date
DE69933131D1 DE69933131D1 (de) 2006-10-19
DE69933131T2 true DE69933131T2 (de) 2007-03-29

Family

ID=11406205

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933131T Expired - Fee Related DE69933131T2 (de) 1998-11-06 1999-11-08 Zellen zur produktion von helper-abhängigen adenoviren-vektoren

Country Status (9)

Country Link
US (1) US6890528B1 (https=)
EP (1) EP1127149B1 (https=)
JP (1) JP2002535961A (https=)
AT (1) ATE338825T1 (https=)
AU (1) AU768489B2 (https=)
CA (1) CA2349594C (https=)
DE (1) DE69933131T2 (https=)
IT (1) IT1302403B1 (https=)
WO (1) WO2000028060A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY139948A (en) * 2000-09-28 2009-11-30 Bayer Corp Enhanced transfection system
US7723102B2 (en) 2000-09-28 2010-05-25 Bayer Corporation Enhanced transfection system
DE602004010112T2 (de) * 2004-09-14 2008-09-18 Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) In cis regulierte konditionelle Genvektoren
GB202410992D0 (en) * 2024-07-26 2024-09-11 Icosphere Biosciences Ltd Process for making gutless helper-dependent adenoviruses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080569A (en) * 1993-06-24 2000-06-27 Merck & Co., Inc. Adenovirus vectors generated from helper viruses and helper-dependent vectors
FR2716459B1 (fr) 1994-02-22 1996-05-10 Univ Paris Curie Système hôte-vecteur utilisable en thérapie génique.
FR2738575B1 (fr) 1995-09-08 1997-10-10 Centre Nat Rech Scient Cellules pour la production d'adenovirus recombinants
SI0833934T2 (sl) * 1995-06-15 2013-04-30 Crucell Holland B.V. Pakirni sistemi za humani rekombinantni adenovirus za uporabo v genski terapiji
US6228646B1 (en) 1996-03-07 2001-05-08 The Regents Of The University Of California Helper-free, totally defective adenovirus for gene therapy
NZ334827A (en) * 1996-09-25 2001-02-23 Scripps Research Inst High-capacity adenoviral vectors suitable for adenoviral-based gene therapy
CZ156098A3 (cs) * 1996-09-26 1998-10-14 Hörmann KG Antriebstechnik Držák ozubeného kotouče pro pohony vrat
WO1999064577A1 (en) * 1998-06-09 1999-12-16 Merck & Co., Inc. Novel adenoviral vectors for gene therapy
CA2340276A1 (en) * 1998-08-28 2000-03-09 Duke University Adenoviruses deleted in the iva2, 100k and/or preterminal protein sequences

Also Published As

Publication number Publication date
WO2000028060A3 (en) 2000-10-05
IT1302403B1 (it) 2000-09-05
ATE338825T1 (de) 2006-09-15
CA2349594A1 (en) 2000-05-18
US6890528B1 (en) 2005-05-10
DE69933131D1 (de) 2006-10-19
ITRM980694A0 (it) 1998-11-06
EP1127149B1 (en) 2006-09-06
AU1294500A (en) 2000-05-29
AU768489B2 (en) 2003-12-11
EP1127149A2 (en) 2001-08-29
WO2000028060A2 (en) 2000-05-18
CA2349594C (en) 2007-02-06
ITRM980694A1 (it) 2000-05-06
JP2002535961A (ja) 2002-10-29

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee