DE69933131D1 - Zellen zur produktion von helper-abhängigen adenoviren-vektoren - Google Patents

Zellen zur produktion von helper-abhängigen adenoviren-vektoren

Info

Publication number
DE69933131D1
DE69933131D1 DE69933131T DE69933131T DE69933131D1 DE 69933131 D1 DE69933131 D1 DE 69933131D1 DE 69933131 T DE69933131 T DE 69933131T DE 69933131 T DE69933131 T DE 69933131T DE 69933131 D1 DE69933131 D1 DE 69933131D1
Authority
DE
Germany
Prior art keywords
cells
helper
genic
production
genic unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69933131T
Other languages
English (en)
Other versions
DE69933131T2 (de
Inventor
Stefano Colloca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto di Ricerche di Biologia Molecolare P Angeletti SpA filed Critical Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Application granted granted Critical
Publication of DE69933131D1 publication Critical patent/DE69933131D1/de
Publication of DE69933131T2 publication Critical patent/DE69933131T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material
    • C12N2710/10352Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69933131T 1998-11-06 1999-11-08 Zellen zur produktion von helper-abhängigen adenoviren-vektoren Expired - Fee Related DE69933131T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1998RM000694A IT1302403B1 (it) 1998-11-06 1998-11-06 Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso.
ITRM980694 1998-11-06
PCT/IT1999/000356 WO2000028060A2 (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors

Publications (2)

Publication Number Publication Date
DE69933131D1 true DE69933131D1 (de) 2006-10-19
DE69933131T2 DE69933131T2 (de) 2007-03-29

Family

ID=11406205

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933131T Expired - Fee Related DE69933131T2 (de) 1998-11-06 1999-11-08 Zellen zur produktion von helper-abhängigen adenoviren-vektoren

Country Status (9)

Country Link
US (1) US6890528B1 (de)
EP (1) EP1127149B1 (de)
JP (1) JP2002535961A (de)
AT (1) ATE338825T1 (de)
AU (1) AU768489B2 (de)
CA (1) CA2349594C (de)
DE (1) DE69933131T2 (de)
IT (1) IT1302403B1 (de)
WO (1) WO2000028060A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7723102B2 (en) 2000-09-28 2010-05-25 Bayer Corporation Enhanced transfection system
MY139948A (en) * 2000-09-28 2009-11-30 Bayer Corp Enhanced transfection system
ES2297315T3 (es) 2004-09-14 2008-05-01 Gsf-Forschungszentrum Fur Umwelt Und Gesundheit Gmbh Vectores geneticos condicionales regulados en cis.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080569A (en) * 1993-06-24 2000-06-27 Merck & Co., Inc. Adenovirus vectors generated from helper viruses and helper-dependent vectors
FR2716459B1 (fr) 1994-02-22 1996-05-10 Univ Paris Curie Système hôte-vecteur utilisable en thérapie génique.
FR2738575B1 (fr) 1995-09-08 1997-10-10 Centre Nat Rech Scient Cellules pour la production d'adenovirus recombinants
EP0833934B2 (de) * 1995-06-15 2012-08-15 Crucell Holland B.V. Verpackungssysteme für humane, menschliche adenoviren, zur verwendung in die gentherapie
US6228646B1 (en) 1996-03-07 2001-05-08 The Regents Of The University Of California Helper-free, totally defective adenovirus for gene therapy
CA2266342C (en) * 1996-09-25 2010-06-08 Novartis Ag Packaging cell lines for use in facilitating the development of high-capacity adenoviral vectors
DE19742704C2 (de) * 1996-09-26 1999-07-22 Hoermann Kg Antriebstechnik Zahnscheibenhalter für Torantriebe
CA2329947A1 (en) * 1998-06-09 1999-12-16 Merck & Co., Inc. Novel adenoviral vectors for gene therapy
IL141403A0 (en) * 1998-08-28 2002-03-10 Univ Duke Deleted adenoviruses and methods of making and administering the same

Also Published As

Publication number Publication date
JP2002535961A (ja) 2002-10-29
US6890528B1 (en) 2005-05-10
AU1294500A (en) 2000-05-29
CA2349594A1 (en) 2000-05-18
ITRM980694A0 (it) 1998-11-06
WO2000028060A2 (en) 2000-05-18
EP1127149A2 (de) 2001-08-29
EP1127149B1 (de) 2006-09-06
AU768489B2 (en) 2003-12-11
WO2000028060A3 (en) 2000-10-05
DE69933131T2 (de) 2007-03-29
IT1302403B1 (it) 2000-09-05
CA2349594C (en) 2007-02-06
ITRM980694A1 (it) 2000-05-06
ATE338825T1 (de) 2006-09-15

Similar Documents

Publication Publication Date Title
TR200003803T2 (tr) Üreme hatalı yeniden bağlayıcı mutasyonlu ana son arttırıcı
AU2002257420A1 (en) A system for inducible expression in eukaryotic cells
ATE282087T1 (de) Modifiziertes enzym mit lipolytischer aktivität
ATE322547T1 (de) Adenovirale vektoren für die behandlung der hämophilie
HUP0301245A2 (hu) Eljárás K-vitamin-függż fehérjék elżállítására
TR200000578T2 (tr) Heparanas aktiviteye sahip olan bir polipeptit deşifre eden polinükleotit ve çevrilmiş hücrelerde aynısını izahı.
BR9812113A (pt) Enzimas de aspergillus degradando celulose
GB2388466B (en) Proton-selective conducting membranes
NZ606504A (en) Modified proteases that inhibit complement activation
NZ596269A (en) Protease screening methods and proteases identified thereby
WO2001086890A3 (en) A method and system for decreasing routing latency for switching platforms with variable configuration
DE60120356D1 (de) Verbesserte galactosylierung von rekombinanten proteinen
NO881670L (no) Diagnostisk proeve paa inhibitor for plasminogenaktivatorerav vev- og urokinasetype, samt gen som koder for inhibitoren.
DE69933131D1 (de) Zellen zur produktion von helper-abhängigen adenoviren-vektoren
HUP0002985A2 (hu) Glicirrizinsavat és legalább egy antivirális hatású proteint tartalmazó vírusellenes gyógyszerkészítmény
ATE435293T1 (de) Invertierte terminale repeats von aav, die für die transkription aktiviert sind, zur verwendung in rekombinanten aav-vektoren
ATE270709T1 (de) Methoden zum aufsuchen von modulatoren der calcineurinaktivität
DE60030430D1 (de) Steuermodul für zwei lufttrockner mit kontinuierlichem strom und steuerverfahren
FI971275A (fi) Inaktivoidun IVa2-geenin käsittävät epätäydelliset yhdistelmä-DNA-tekniset adenovirukset
TR199801300T2 (xx) Selülaz ve oksidoredüktaz ile muamele edilen kumaş.
DE69730139D1 (de) Neuartige expressionsvektoren
AU7720598A (en) Disinfection by particle-bound and insolubilized detergents
WO2000026395A3 (en) Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
CA2146240A1 (en) Increased production of secreted proteins by recombinant eukaryotic cells
WO1999037758A3 (en) Expression of proteolytically-sensitive peptides

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee