AU768489B2 - Cells for the production of helper dependent adenoviral vectors, method for the preparation and use thereof - Google Patents
Cells for the production of helper dependent adenoviral vectors, method for the preparation and use thereof Download PDFInfo
- Publication number
- AU768489B2 AU768489B2 AU12945/00A AU1294500A AU768489B2 AU 768489 B2 AU768489 B2 AU 768489B2 AU 12945/00 A AU12945/00 A AU 12945/00A AU 1294500 A AU1294500 A AU 1294500A AU 768489 B2 AU768489 B2 AU 768489B2
- Authority
- AU
- Australia
- Prior art keywords
- cells
- unit
- regions
- genic
- cells according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
- C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM98A000694 | 1998-11-06 | ||
| IT1998RM000694A IT1302403B1 (it) | 1998-11-06 | 1998-11-06 | Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso. |
| PCT/IT1999/000356 WO2000028060A2 (en) | 1998-11-06 | 1999-11-08 | Cells for the production of helper dependent adenoviral vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1294500A AU1294500A (en) | 2000-05-29 |
| AU768489B2 true AU768489B2 (en) | 2003-12-11 |
Family
ID=11406205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU12945/00A Ceased AU768489B2 (en) | 1998-11-06 | 1999-11-08 | Cells for the production of helper dependent adenoviral vectors, method for the preparation and use thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6890528B1 (https=) |
| EP (1) | EP1127149B1 (https=) |
| JP (1) | JP2002535961A (https=) |
| AT (1) | ATE338825T1 (https=) |
| AU (1) | AU768489B2 (https=) |
| CA (1) | CA2349594C (https=) |
| DE (1) | DE69933131T2 (https=) |
| IT (1) | IT1302403B1 (https=) |
| WO (1) | WO2000028060A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY139948A (en) * | 2000-09-28 | 2009-11-30 | Bayer Corp | Enhanced transfection system |
| US7723102B2 (en) | 2000-09-28 | 2010-05-25 | Bayer Corporation | Enhanced transfection system |
| DE602004010112T2 (de) * | 2004-09-14 | 2008-09-18 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | In cis regulierte konditionelle Genvektoren |
| GB202410992D0 (en) * | 2024-07-26 | 2024-09-11 | Icosphere Biosciences Ltd | Process for making gutless helper-dependent adenoviruses |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997000326A1 (en) * | 1995-06-15 | 1997-01-03 | Introgene B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| WO1998013570A1 (de) * | 1996-09-26 | 1998-04-02 | Hörmann KG Antriebstechnik | Zahnscheibenhalter für torantriebe |
| WO1999064577A1 (en) * | 1998-06-09 | 1999-12-16 | Merck & Co., Inc. | Novel adenoviral vectors for gene therapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6080569A (en) * | 1993-06-24 | 2000-06-27 | Merck & Co., Inc. | Adenovirus vectors generated from helper viruses and helper-dependent vectors |
| FR2716459B1 (fr) | 1994-02-22 | 1996-05-10 | Univ Paris Curie | Système hôte-vecteur utilisable en thérapie génique. |
| FR2738575B1 (fr) | 1995-09-08 | 1997-10-10 | Centre Nat Rech Scient | Cellules pour la production d'adenovirus recombinants |
| US6228646B1 (en) | 1996-03-07 | 2001-05-08 | The Regents Of The University Of California | Helper-free, totally defective adenovirus for gene therapy |
| NZ334827A (en) * | 1996-09-25 | 2001-02-23 | Scripps Research Inst | High-capacity adenoviral vectors suitable for adenoviral-based gene therapy |
| CA2340276A1 (en) * | 1998-08-28 | 2000-03-09 | Duke University | Adenoviruses deleted in the iva2, 100k and/or preterminal protein sequences |
-
1998
- 1998-11-06 IT IT1998RM000694A patent/IT1302403B1/it active IP Right Grant
-
1999
- 1999-11-08 EP EP99956316A patent/EP1127149B1/en not_active Expired - Lifetime
- 1999-11-08 AU AU12945/00A patent/AU768489B2/en not_active Ceased
- 1999-11-08 AT AT99956316T patent/ATE338825T1/de not_active IP Right Cessation
- 1999-11-08 CA CA002349594A patent/CA2349594C/en not_active Expired - Fee Related
- 1999-11-08 US US09/831,182 patent/US6890528B1/en not_active Expired - Fee Related
- 1999-11-08 DE DE69933131T patent/DE69933131T2/de not_active Expired - Fee Related
- 1999-11-08 JP JP2000581226A patent/JP2002535961A/ja active Pending
- 1999-11-08 WO PCT/IT1999/000356 patent/WO2000028060A2/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997000326A1 (en) * | 1995-06-15 | 1997-01-03 | Introgene B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| WO1998013570A1 (de) * | 1996-09-26 | 1998-04-02 | Hörmann KG Antriebstechnik | Zahnscheibenhalter für torantriebe |
| WO1999064577A1 (en) * | 1998-06-09 | 1999-12-16 | Merck & Co., Inc. | Novel adenoviral vectors for gene therapy |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69933131T2 (de) | 2007-03-29 |
| WO2000028060A3 (en) | 2000-10-05 |
| IT1302403B1 (it) | 2000-09-05 |
| ATE338825T1 (de) | 2006-09-15 |
| CA2349594A1 (en) | 2000-05-18 |
| US6890528B1 (en) | 2005-05-10 |
| DE69933131D1 (de) | 2006-10-19 |
| ITRM980694A0 (it) | 1998-11-06 |
| EP1127149B1 (en) | 2006-09-06 |
| AU1294500A (en) | 2000-05-29 |
| EP1127149A2 (en) | 2001-08-29 |
| WO2000028060A2 (en) | 2000-05-18 |
| CA2349594C (en) | 2007-02-06 |
| ITRM980694A1 (it) | 2000-05-06 |
| JP2002535961A (ja) | 2002-10-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6365394B1 (en) | Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus | |
| EP0870049B1 (en) | Complementary adenoviral vector systems and cell lines | |
| AU687829B2 (en) | Adenovirus vectors for gene therapy | |
| WO1998039411A9 (en) | Adenovirus e1-complementing cell lines | |
| WO1998039411A1 (en) | Adenovirus e1-complementing cell lines | |
| Catalucci et al. | An adenovirus type 5 (Ad5) amplicon-based packaging cell line for production of high-capacity helper-independent ΔE1-E2-E3-E4 Ad5 vectors | |
| AU752284B2 (en) | Methods for pseudoadenoviral vector production | |
| AU768489B2 (en) | Cells for the production of helper dependent adenoviral vectors, method for the preparation and use thereof | |
| US20010046965A1 (en) | Adenovirus E1-complementing cell lines | |
| EP1291434A2 (en) | Efficient generation of adenovirus-based libraries by positive selection of adenoviral recombinants through ectopic expression of the adenovirus protease | |
| EP1083229A1 (en) | Modified adenoviral vectors for use in gene therapy | |
| WO1998032860A1 (en) | Methods for highly efficient generation of adenoviral vectors | |
| WO2001034825A1 (en) | Ptp/dna polymerase cell line as packaging cell line for minimal adenoviral vectors | |
| Morris et al. | Generation of cell lines to complement adenovirus vectors using recombination-mediated cassette exchange | |
| WO2001020014A1 (en) | Modified adenoviral vectors for use in gene therapy | |
| US7585498B2 (en) | Regulation of adenovirus DNA packaging by IPTG | |
| WO2026022346A2 (en) | Process for making gutless helper-dependent adenoviruses | |
| Morsy et al. | Helper-dependent adenoviral vectors as gene delivery vehicles |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |