IT1302403B1 - Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso. - Google Patents

Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso.

Info

Publication number
IT1302403B1
IT1302403B1 IT1998RM000694A ITRM980694A IT1302403B1 IT 1302403 B1 IT1302403 B1 IT 1302403B1 IT 1998RM000694 A IT1998RM000694 A IT 1998RM000694A IT RM980694 A ITRM980694 A IT RM980694A IT 1302403 B1 IT1302403 B1 IT 1302403B1
Authority
IT
Italy
Prior art keywords
cells
adenoviral vectors
genic
production
genic unit
Prior art date
Application number
IT1998RM000694A
Other languages
English (en)
Italian (it)
Inventor
Stefano Colloca
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Publication of ITRM980694A0 publication Critical patent/ITRM980694A0/it
Priority to IT1998RM000694A priority Critical patent/IT1302403B1/it
Priority to PCT/IT1999/000356 priority patent/WO2000028060A2/en
Priority to JP2000581226A priority patent/JP2002535961A/ja
Priority to DE69933131T priority patent/DE69933131T2/de
Priority to CA002349594A priority patent/CA2349594C/en
Priority to AT99956316T priority patent/ATE338825T1/de
Priority to EP99956316A priority patent/EP1127149B1/en
Priority to AU12945/00A priority patent/AU768489B2/en
Priority to US09/831,182 priority patent/US6890528B1/en
Publication of ITRM980694A1 publication Critical patent/ITRM980694A1/it
Application granted granted Critical
Publication of IT1302403B1 publication Critical patent/IT1302403B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT1998RM000694A 1998-11-06 1998-11-06 Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso. IT1302403B1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT1998RM000694A IT1302403B1 (it) 1998-11-06 1998-11-06 Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso.
CA002349594A CA2349594C (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors
JP2000581226A JP2002535961A (ja) 1998-11-06 1999-11-08 ヘルパー依存性アデノウイルスベクター生産用細胞の製法およびその使用法
DE69933131T DE69933131T2 (de) 1998-11-06 1999-11-08 Zellen zur produktion von helper-abhängigen adenoviren-vektoren
PCT/IT1999/000356 WO2000028060A2 (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors
AT99956316T ATE338825T1 (de) 1998-11-06 1999-11-08 Zellen zur produktion von helper-abhängigen adenoviren-vektoren
EP99956316A EP1127149B1 (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors
AU12945/00A AU768489B2 (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors, method for the preparation and use thereof
US09/831,182 US6890528B1 (en) 1998-11-06 1999-11-08 Cells for the production of helper dependent adenoviral vectors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998RM000694A IT1302403B1 (it) 1998-11-06 1998-11-06 Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso.

Publications (3)

Publication Number Publication Date
ITRM980694A0 ITRM980694A0 (it) 1998-11-06
ITRM980694A1 ITRM980694A1 (it) 2000-05-06
IT1302403B1 true IT1302403B1 (it) 2000-09-05

Family

ID=11406205

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998RM000694A IT1302403B1 (it) 1998-11-06 1998-11-06 Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso.

Country Status (9)

Country Link
US (1) US6890528B1 (https=)
EP (1) EP1127149B1 (https=)
JP (1) JP2002535961A (https=)
AT (1) ATE338825T1 (https=)
AU (1) AU768489B2 (https=)
CA (1) CA2349594C (https=)
DE (1) DE69933131T2 (https=)
IT (1) IT1302403B1 (https=)
WO (1) WO2000028060A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7723102B2 (en) 2000-09-28 2010-05-25 Bayer Corporation Enhanced transfection system
MY139948A (en) * 2000-09-28 2009-11-30 Bayer Corp Enhanced transfection system
EP1634955B1 (en) * 2004-09-14 2007-11-14 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Conditional gene vectors regulated in cis
GB202410992D0 (en) * 2024-07-26 2024-09-11 Icosphere Biosciences Ltd Process for making gutless helper-dependent adenoviruses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080569A (en) 1993-06-24 2000-06-27 Merck & Co., Inc. Adenovirus vectors generated from helper viruses and helper-dependent vectors
FR2716459B1 (fr) 1994-02-22 1996-05-10 Univ Paris Curie Système hôte-vecteur utilisable en thérapie génique.
FR2738575B1 (fr) 1995-09-08 1997-10-10 Centre Nat Rech Scient Cellules pour la production d'adenovirus recombinants
IL160406A0 (en) * 1995-06-15 2004-07-25 Crucell Holland Bv A cell harbouring nucleic acid encoding adenoritus e1a and e1b gene products
AU2319497A (en) 1996-03-07 1997-09-22 Regents Of The University Of California, The Helper-free, totally defective adenovirus for gene therapy
EP0937150A2 (en) * 1996-09-25 1999-08-25 Novartis AG Packaging cell lines for use in facilitating the development of high-capacity adenoviral vectors
PL327071A1 (en) * 1996-09-26 1998-11-23 Hormann Kg Antriebstechnik Toothed disk holder for gate opening/closing mechanism
JP2002517234A (ja) * 1998-06-09 2002-06-18 メルク・アンド・カンパニー・インコーポレーテッド 遺伝子治療用の新規アデノウイルスベクター
WO2000012740A2 (en) 1998-08-28 2000-03-09 Duke University ADENOVIRUSES DELETED IN THE IVa2, 100K AND/OR PRETERMINAL PROTEIN SEQUENCES

Also Published As

Publication number Publication date
ITRM980694A1 (it) 2000-05-06
US6890528B1 (en) 2005-05-10
AU768489B2 (en) 2003-12-11
DE69933131T2 (de) 2007-03-29
EP1127149B1 (en) 2006-09-06
ITRM980694A0 (it) 1998-11-06
WO2000028060A3 (en) 2000-10-05
WO2000028060A2 (en) 2000-05-18
EP1127149A2 (en) 2001-08-29
DE69933131D1 (de) 2006-10-19
AU1294500A (en) 2000-05-29
CA2349594C (en) 2007-02-06
JP2002535961A (ja) 2002-10-29
CA2349594A1 (en) 2000-05-18
ATE338825T1 (de) 2006-09-15

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