ATE496123T1 - Nukleinsäuren, welche für tramsmembran serin proteasen kodieren, die kodierten proteine und darauf basierende methoden - Google Patents
Nukleinsäuren, welche für tramsmembran serin proteasen kodieren, die kodierten proteine und darauf basierende methodenInfo
- Publication number
- ATE496123T1 ATE496123T1 AT01905377T AT01905377T ATE496123T1 AT E496123 T1 ATE496123 T1 AT E496123T1 AT 01905377 T AT01905377 T AT 01905377T AT 01905377 T AT01905377 T AT 01905377T AT E496123 T1 ATE496123 T1 AT E496123T1
- Authority
- AT
- Austria
- Prior art keywords
- tram
- code
- nucleic acids
- methods based
- serine proteases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Laminated Bodies (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17998200P | 2000-02-03 | 2000-02-03 | |
US18354200P | 2000-02-18 | 2000-02-18 | |
US21312400P | 2000-06-22 | 2000-06-22 | |
US22097000P | 2000-07-26 | 2000-07-26 | |
US09/657,986 US6797504B1 (en) | 2000-09-08 | 2000-09-08 | Inhibitors of serine protease activity of matriptase or MTSP1 |
US23484000P | 2000-09-22 | 2000-09-22 | |
PCT/US2001/003471 WO2001057194A2 (en) | 2000-02-03 | 2001-02-02 | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE496123T1 true ATE496123T1 (de) | 2011-02-15 |
Family
ID=27558705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01905377T ATE496123T1 (de) | 2000-02-03 | 2001-02-02 | Nukleinsäuren, welche für tramsmembran serin proteasen kodieren, die kodierten proteine und darauf basierende methoden |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1252300B1 (de) |
JP (1) | JP2003521920A (de) |
KR (1) | KR20020073576A (de) |
AT (1) | ATE496123T1 (de) |
AU (1) | AU2001233262A1 (de) |
CA (1) | CA2396774A1 (de) |
DE (1) | DE60143880D1 (de) |
IL (1) | IL150168A0 (de) |
WO (1) | WO2001057194A2 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030039648A1 (en) | 1998-09-16 | 2003-02-27 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US7037667B1 (en) | 1998-06-01 | 2006-05-02 | Agensys, Inc. | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
US6291663B1 (en) * | 1999-03-03 | 2001-09-18 | Board Of Trustees Of The University Of Arkansas | TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma |
KR20020056923A (ko) | 1999-11-18 | 2002-07-10 | 코르바스 인터내셔날, 인코포레이티드 | 엔도텔리아제를 암호화하는 핵산, 엔도텔리아제 및 이의용도 |
EP1280923A2 (de) | 2000-04-28 | 2003-02-05 | Millennium Pharmaceuticals, Inc. | 14094, ein angehörige der menschlichen trypsin-familie, und dessen verwendungen |
US6750034B1 (en) | 2000-06-30 | 2004-06-15 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human serine protease D-G |
WO2002006455A2 (en) * | 2000-07-19 | 2002-01-24 | Bayer Aktiengesellschaft | Regulation of human airway trypsin protease-like enzyme |
US7157596B2 (en) | 2000-09-08 | 2007-01-02 | Dendreon Corporation | Inhibitors of serine protease activity of matriptase or MTSP1 |
JP2004337001A (ja) * | 2001-01-23 | 2004-12-02 | Mochida Pharmaceut Co Ltd | 新規なセリンプロテアーゼmp493 |
US7229774B2 (en) | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
US7332290B2 (en) | 2001-08-02 | 2008-02-19 | The Regents Of The University Of Michigan | Dectection of AMACR cancer markers in urine |
US7700293B2 (en) | 2001-08-02 | 2010-04-20 | The Regents Of The University Of Michigan | Expression profile of prostate cancer |
KR20040111525A (ko) * | 2002-04-17 | 2004-12-31 | 제넨테크, 인크. | 종양의 진단 및 치료 방법 및 이를 위한 조성물 |
WO2003102135A2 (en) * | 2002-05-31 | 2003-12-11 | Schering Aktiengesellschaft | Control sequences of the human corin gene |
US20060134719A1 (en) * | 2002-07-31 | 2006-06-22 | Masayoshi Takeda | Novel serine protease |
US6977170B2 (en) * | 2002-09-06 | 2005-12-20 | Applera Corporation | Isolated human hepsin/46 proteins, nucleic acid molecules encoding human hepsin/46 proteins, and uses thereof |
US7939304B2 (en) | 2002-10-02 | 2011-05-10 | Catalyst Biosciences, Inc. | Mutant MT-SP1 proteases with altered substrate specificity or activity |
DE10258051A1 (de) * | 2002-12-11 | 2004-07-22 | Metagen Pharmaceuticals Gmbh | Verwendung von an HAT bindenden Substanzen zur Diagnose und Behandlung des Plattenepithelkarzinoms der Lunge |
US7019019B2 (en) | 2002-12-23 | 2006-03-28 | Dendreon Corporation | Matriptase inhibitors and methods of use |
WO2004065599A1 (ja) * | 2003-01-24 | 2004-08-05 | Eisai Co., Ltd. | Lrp4/Corinドーパミン産生ニューロン増殖前駆細胞マーカー |
EP1636356A1 (de) * | 2003-06-11 | 2006-03-22 | Schering Aktiengesellschaft | Neue modifizierte corin moleküle mit substituierten aktivierungssequenzen und ihre verwendungen |
US7476512B2 (en) | 2004-02-27 | 2009-01-13 | The General Hospital Corporation | Methods of identifying dermal papilla cells |
JP5629423B2 (ja) | 2004-04-12 | 2014-11-19 | カタリスト バイオサイエンシーズ, インコーポレイテッド | 野生型及び変異型mt−sp1による、vegf及びvegf受容体の切断 |
DE102004023187A1 (de) * | 2004-05-11 | 2005-12-01 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
JP3996627B2 (ja) | 2004-07-22 | 2007-10-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Lrp4/Corinドーパミン産生ニューロン前駆細胞マーカー |
CN101292031A (zh) | 2005-08-18 | 2008-10-22 | 卫材R&D管理有限公司 | 多巴胺能神经元增殖祖细胞的标记物Nato3 |
WO2007047995A2 (en) | 2005-10-21 | 2007-04-26 | Catalyst Biosciences, Inc. | Modified proteases that inhibit complement activation |
NZ573417A (en) * | 2006-06-22 | 2012-01-12 | Genentech Inc | Methods and compositions for modulating hepsin activation of urokinase-type plasminogen activator |
CN101490088B (zh) | 2006-06-22 | 2015-04-08 | 健泰科生物技术公司 | 用于靶向hepsin的方法和组合物 |
KR20150033726A (ko) | 2006-07-05 | 2015-04-01 | 카탈리스트 바이오사이언시즈, 인코포레이티드 | 프로테아제 스크리닝 방법 및 이에 의해 확인된 프로테아제 |
GB0614201D0 (en) * | 2006-07-18 | 2006-08-23 | Univ Cardiff | Matriptase-2 |
EP2185933B1 (de) | 2007-08-07 | 2015-10-07 | Oxford Biotherapeutics Ltd. | Matriptase-protein und verwendungen davon |
KR101500670B1 (ko) * | 2010-11-02 | 2015-03-10 | 인하대학교 산학협력단 | 암전이를 억제하는 항원 펩타이드, 이를 포함하는 암전이 백신, 암전이 억제 및 치료용 조성물 그리고 암전이 관련 표적물질 및 암전이 억제물질의 스크린 방법 |
JP6090937B2 (ja) | 2011-07-27 | 2017-03-08 | 国立大学法人京都大学 | 新規ドーパミン産生神経前駆細胞マーカー |
AR098523A1 (es) | 2013-11-25 | 2016-06-01 | Oxford Biotherapeutics Ltd | Anticuerpos dirigidos contra matriptasa y composiciones relacionadas |
WO2017162659A1 (en) | 2016-03-24 | 2017-09-28 | Bayer Pharma Aktiengesellschaft | Intracellular hepsin as therapeutic target for the treatment of cancer with centrosome amplification |
US20210070823A1 (en) * | 2019-04-05 | 2021-03-11 | Azitra Inc | Methods and compositions for treating atopic dermatitis with recombinant microorganisms |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4952496A (en) | 1984-03-30 | 1990-08-28 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
JP3488465B2 (ja) | 1993-10-28 | 2004-01-19 | ヒューストン・アドバンスド・リサーチ・センター | 結合反応を別々に検出する微細加工フロースルー多孔性装置 |
JPH09149790A (ja) * | 1995-09-29 | 1997-06-10 | Suntory Ltd | 新規セリンプロテアーゼ |
US6203979B1 (en) * | 1998-01-16 | 2001-03-20 | Incyte Pharmaceuticals, Inc. | Human protease molecules |
US5972616A (en) | 1998-02-20 | 1999-10-26 | The Board Of Trustees Of The University Of Arkansas | TADG-15: an extracellular serine protease overexpressed in breast and ovarian carcinomas |
DK1490386T3 (da) * | 1998-03-10 | 2008-12-15 | Genentech Inc | Nyt polypeptid og nukleinsyrer kodende for dette |
US6291663B1 (en) * | 1999-03-03 | 2001-09-18 | Board Of Trustees Of The University Of Arkansas | TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma |
WO2001004141A2 (de) * | 1999-07-12 | 2001-01-18 | Merck Patent Gmbh | Seripancrin |
-
2001
- 2001-02-02 AU AU2001233262A patent/AU2001233262A1/en not_active Abandoned
- 2001-02-02 EP EP01905377A patent/EP1252300B1/de not_active Expired - Lifetime
- 2001-02-02 DE DE60143880T patent/DE60143880D1/de not_active Expired - Lifetime
- 2001-02-02 AT AT01905377T patent/ATE496123T1/de not_active IP Right Cessation
- 2001-02-02 IL IL15016801A patent/IL150168A0/xx unknown
- 2001-02-02 WO PCT/US2001/003471 patent/WO2001057194A2/en active Application Filing
- 2001-02-02 KR KR1020027009973A patent/KR20020073576A/ko not_active Application Discontinuation
- 2001-02-02 JP JP2001558009A patent/JP2003521920A/ja active Pending
- 2001-02-02 CA CA002396774A patent/CA2396774A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001057194A2 (en) | 2001-08-09 |
WO2001057194A3 (en) | 2002-03-28 |
EP1252300A2 (de) | 2002-10-30 |
IL150168A0 (en) | 2002-12-01 |
CA2396774A1 (en) | 2001-08-09 |
JP2003521920A (ja) | 2003-07-22 |
KR20020073576A (ko) | 2002-09-27 |
AU2001233262A1 (en) | 2001-08-14 |
DE60143880D1 (de) | 2011-03-03 |
EP1252300B1 (de) | 2011-01-19 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |