ATE485303T1 - Isoformen von gehirn-natriuretischem peptid - Google Patents
Isoformen von gehirn-natriuretischem peptidInfo
- Publication number
- ATE485303T1 ATE485303T1 AT04754213T AT04754213T ATE485303T1 AT E485303 T1 ATE485303 T1 AT E485303T1 AT 04754213 T AT04754213 T AT 04754213T AT 04754213 T AT04754213 T AT 04754213T AT E485303 T1 ATE485303 T1 AT E485303T1
- Authority
- AT
- Austria
- Prior art keywords
- isoforms
- natriuretic peptide
- brain natriuretic
- conditions
- kidney
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48046003P | 2003-06-20 | 2003-06-20 | |
PCT/US2004/017554 WO2005000095A2 (en) | 2003-06-20 | 2004-06-02 | Isoforms of brain natriuretic peptide |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE485303T1 true ATE485303T1 (de) | 2010-11-15 |
Family
ID=33551922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04754213T ATE485303T1 (de) | 2003-06-20 | 2004-06-02 | Isoformen von gehirn-natriuretischem peptid |
Country Status (12)
Country | Link |
---|---|
US (2) | US8354496B2 (de) |
EP (2) | EP1638443B1 (de) |
JP (1) | JP4881156B2 (de) |
CN (1) | CN101208353B (de) |
AT (1) | ATE485303T1 (de) |
DE (1) | DE602004029680D1 (de) |
DK (1) | DK1638443T3 (de) |
ES (1) | ES2354881T3 (de) |
IL (1) | IL172674A (de) |
PL (1) | PL1638443T3 (de) |
PT (1) | PT1638443E (de) |
WO (1) | WO2005000095A2 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004029680D1 (de) | 2003-06-20 | 2010-12-02 | Mayo Foundation | Isoformen von gehirn-natriuretischem peptid |
EP1698058A4 (de) * | 2003-12-18 | 2009-09-23 | Inverness Medical Switzerland | Überwachungsverfahren und -vorrichtung |
GB0329288D0 (en) | 2003-12-18 | 2004-01-21 | Inverness Medical Switzerland | Monitoring method and apparatus |
PL2348114T3 (pl) | 2004-04-21 | 2019-08-30 | Alexion Pharmaceuticals, Inc. | Koniugaty do dostarczania do kości i sposób ich wykorzystania do nakierowywania białek na kość |
US20070042957A1 (en) * | 2005-08-19 | 2007-02-22 | Mayo Foundation For Medical Education And Research | Type v phosphodiesterase inhibitors and natriuretic polypeptides |
KR100702415B1 (ko) * | 2006-03-03 | 2007-04-09 | 안웅식 | 올리고 핵산 탐침 비드 어레이를 이용한 인유두종바이러스검출 키트 및 방법 |
KR100736442B1 (ko) * | 2006-03-10 | 2007-07-09 | 주식회사 나노텍세라믹스 | 라텍스 바인딩된 저비산 실리카 조성물과 이의 제조방법 |
WO2008021872A1 (en) * | 2006-08-08 | 2008-02-21 | Mayo Foundation For Medical Education And Research | Diuretic and natriuretic polypeptides |
EP2295445A1 (de) | 2006-09-08 | 2011-03-16 | Mayo Foundation for Medical Education and Research | Aquaretische und natriuretische Polypeptide ohne Gefäßerweiterungsaktivität |
WO2009036448A2 (en) * | 2007-09-15 | 2009-03-19 | Mayo Foundation For Medical Education And Research | Natriuretic peptide receptor-c agonists |
WO2010029116A1 (en) * | 2008-09-11 | 2010-03-18 | F. Hoffmann-La Roche Ag | Natriuretic peptides and adiponectin in subjects with a metabolic syndrome |
JP4834190B2 (ja) | 2009-07-23 | 2011-12-14 | 株式会社 イギス | 皮膚外用剤組成物 |
NZ598600A (en) | 2009-08-27 | 2014-03-28 | Kyoko Endo | Therapeutic agent for rhinitis |
AU2011350066A1 (en) | 2010-12-27 | 2013-07-11 | Alexion Pharma International Sarl | Compositions comprising natriuretic peptides and methods of use thereof |
CN102174636B (zh) * | 2011-01-11 | 2013-10-30 | 中国食品药品检定研究院 | 应用gca稳定转染细胞系测定bnp活性 |
CN110801514A (zh) | 2011-01-21 | 2020-02-18 | Igisu株式会社 | 秃头症治疗剂 |
WO2013032784A1 (en) | 2011-08-30 | 2013-03-07 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
WO2013070741A1 (en) * | 2011-11-11 | 2013-05-16 | Mayo Foundation For Medical Education And Research | Methods and materials for regulating natriuretic polypeptide function |
US9611305B2 (en) | 2012-01-06 | 2017-04-04 | Mayo Foundation For Medical Education And Research | Treating cardiovascular or renal diseases |
US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
JP6532460B2 (ja) * | 2013-07-26 | 2019-06-19 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 患者モニタリングシステムに関する臨床規則及び規定のコンピュータ化及び視覚化 |
WO2016007873A1 (en) | 2014-07-11 | 2016-01-14 | The Regents Of The University Of Michigan | Compositions and methods for treating craniosynostosis |
CN107405390A (zh) | 2014-12-05 | 2017-11-28 | 阿雷克森制药公司 | 用重组碱性磷酸酶治疗癫痫 |
CA2973883A1 (en) | 2015-01-28 | 2016-08-04 | Alexion Pharmaceuticals, Inc. | Methods of treating a subject with an alkaline phosphatase deficiency |
WO2017031114A1 (en) | 2015-08-17 | 2017-02-23 | Alexion Pharmaceuticals, Inc. | Manufacturing of alkaline phosphatases |
EP3355904A4 (de) | 2015-09-28 | 2019-06-12 | Alexion Pharmaceuticals, Inc. | Identifizierung wirksamer dosierungsschemata für gewebeunspezifische alkalische phosphatase-enzymersatztherapie von hypophosphatasie |
WO2017074466A1 (en) | 2015-10-30 | 2017-05-04 | Alexion Pharmaceuticals, Inc. | Methods for treating craniosynostosis in a patient |
US11065306B2 (en) | 2016-03-08 | 2021-07-20 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
WO2017173395A1 (en) | 2016-04-01 | 2017-10-05 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in adolescents and adults |
EP3436052A4 (de) | 2016-04-01 | 2019-10-09 | Alexion Pharmaceuticals, Inc. | Behandlung von muskelschwäche mit alkalischen phosphatasen |
EP3464573A4 (de) | 2016-06-06 | 2020-02-19 | Alexion Pharmaceuticals, Inc. | Auswirkungen von metallen auf die herstellung von alkalischen phosphatasen |
WO2018035420A1 (en) | 2016-08-18 | 2018-02-22 | Alexion Pharmaceuticals, Inc. | Methods for treating tracheobronchomalacia |
BR112019020506A2 (pt) | 2017-03-31 | 2020-08-04 | Alexion Pharmaceuticals, Inc. | métodos para o tratamento de hipofosfatasia (hpp) em adultos e adolescentes |
EP3773684A1 (de) | 2018-03-30 | 2021-02-17 | Alexion Pharmaceuticals, Inc. | Herstellung von glycoproteinen |
BR112023016048A2 (pt) | 2021-02-12 | 2023-11-14 | Alexion Pharma Inc | Polipeptídeos de fosfatase alcalina e métodos de uso dos mesmos |
TW202419463A (zh) | 2022-11-02 | 2024-05-16 | 丹麥商諾佛 儂迪克股份有限公司 | Cnp化合物 |
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US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
US4233402A (en) | 1978-04-05 | 1980-11-11 | Syva Company | Reagents and method employing channeling |
WO1984003285A1 (en) | 1983-02-22 | 1984-08-30 | Molecular Biosystems Inc | Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis |
US4506671A (en) | 1983-03-30 | 1985-03-26 | United States Surgical Corporation | Apparatus for applying two-part surgical fasteners |
US4496544A (en) | 1983-11-10 | 1985-01-29 | Washington University | Atrial Peptides |
US5212286A (en) | 1984-04-19 | 1993-05-18 | Scios Nova Inc. | Atrial natriuretic/vasodilator peptide compounds |
US4996143A (en) | 1985-12-23 | 1991-02-26 | Syngene, Inc. | Fluorescent stokes shift probes for polynucleotide hybridization |
US5114923A (en) | 1988-05-31 | 1992-05-19 | California Biotechnology Inc. | Recombinant techniques for production of novel natriuretic and vasodilator peptides |
CA1339210C (en) * | 1988-05-31 | 1997-08-05 | John Lewicki | Recombinant techniques for production of novel natriuretic and vasodilator peptides |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
JP2809533B2 (ja) * | 1991-01-31 | 1998-10-08 | 壽之 松尾 | Cnp類似体ペプチド |
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EP1067134B1 (de) | 1991-11-07 | 2004-07-28 | Nanotronics, Inc. | Hybridisierung von mit Chromophoren und Fluorophoren konjugierten Polynukleotiden zur Erzeugung eines Donor-Donor Energietransfersystems |
WO1994020534A1 (en) * | 1993-03-03 | 1994-09-15 | Mayo Foundation For Medical Education And Research | Vasonatrin peptide and analogs thereof |
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US5665704A (en) * | 1993-11-12 | 1997-09-09 | Genentech, Inc. | Receptor specific atrial natriuretic peptides |
WO1995024419A1 (en) * | 1994-03-11 | 1995-09-14 | Ariad Pharmaceuticals, Inc. | Methods and materials for identifying inhibitors of molecular interactions mediated by sh3 domains |
EP2292662B1 (de) | 1996-03-04 | 2014-04-23 | Scios Inc. | Testverfahren und Reagenzien zur Quantifizierung von hBNP |
US6828107B2 (en) * | 1997-09-11 | 2004-12-07 | Shionogi & Co., Ltd. | Immunoassay method for BNP |
US6551795B1 (en) | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
US6887481B1 (en) * | 1998-12-16 | 2005-05-03 | Agency For Science, Technology And Research | Bacterial-derived molecules and therapeutic and diagnostic uses therefor |
US6887470B1 (en) | 1999-09-10 | 2005-05-03 | Conjuchem, Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
US6849714B1 (en) | 1999-05-17 | 2005-02-01 | Conjuchem, Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
WO2000071576A2 (en) | 1999-05-24 | 2000-11-30 | Mayo Foundation For Medical Education And Research | Adenovirus vectors encoding brain natriuretic peptide |
US6407211B1 (en) | 1999-12-17 | 2002-06-18 | Mayo Foundation For Medical Education And Research | Chimeric natriuretic peptides |
US20110131679A2 (en) * | 2000-04-19 | 2011-06-02 | Thomas La Rosa | Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
AU2002224331A1 (en) * | 2000-09-22 | 2002-04-02 | Incyte Genomics, Inc. | Transcription factors and zinc finger proteins |
US7214786B2 (en) * | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
DE602004029680D1 (de) | 2003-06-20 | 2010-12-02 | Mayo Foundation | Isoformen von gehirn-natriuretischem peptid |
US7332569B2 (en) | 2004-01-27 | 2008-02-19 | Compugen Ltd. | Brain natriuretic peptide spliced variant |
EP1730181A2 (de) | 2004-01-27 | 2006-12-13 | Compugen USA, Inc. | Neue natriuretische peptidvarianten im gehirn und anwendungsverfahren |
WO2008021872A1 (en) | 2006-08-08 | 2008-02-21 | Mayo Foundation For Medical Education And Research | Diuretic and natriuretic polypeptides |
WO2009036448A2 (en) | 2007-09-15 | 2009-03-19 | Mayo Foundation For Medical Education And Research | Natriuretic peptide receptor-c agonists |
-
2004
- 2004-06-02 DE DE602004029680T patent/DE602004029680D1/de not_active Expired - Lifetime
- 2004-06-02 JP JP2006517173A patent/JP4881156B2/ja not_active Expired - Fee Related
- 2004-06-02 EP EP04754213A patent/EP1638443B1/de not_active Expired - Lifetime
- 2004-06-02 PT PT04754213T patent/PT1638443E/pt unknown
- 2004-06-02 AT AT04754213T patent/ATE485303T1/de active
- 2004-06-02 PL PL04754213T patent/PL1638443T3/pl unknown
- 2004-06-02 WO PCT/US2004/017554 patent/WO2005000095A2/en active Application Filing
- 2004-06-02 DK DK04754213.9T patent/DK1638443T3/da active
- 2004-06-02 ES ES04754213T patent/ES2354881T3/es not_active Expired - Lifetime
- 2004-06-02 CN CN2004800209647A patent/CN101208353B/zh not_active Expired - Fee Related
- 2004-06-02 EP EP10187879.1A patent/EP2308889B1/de not_active Expired - Lifetime
- 2004-06-02 US US10/561,014 patent/US8354496B2/en not_active Expired - Fee Related
-
2005
- 2005-12-19 IL IL172674A patent/IL172674A/en active IP Right Grant
-
2012
- 2012-09-14 US US13/616,244 patent/US8912137B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101208353B (zh) | 2011-12-14 |
EP1638443B1 (de) | 2010-10-20 |
DK1638443T3 (da) | 2011-02-07 |
CN101208353A (zh) | 2008-06-25 |
EP2308889A1 (de) | 2011-04-13 |
WO2005000095A3 (en) | 2008-01-24 |
JP2007525957A (ja) | 2007-09-13 |
US20070281887A1 (en) | 2007-12-06 |
IL172674A (en) | 2011-08-31 |
US8354496B2 (en) | 2013-01-15 |
IL172674A0 (en) | 2006-04-10 |
PL1638443T3 (pl) | 2011-04-29 |
US20130143816A1 (en) | 2013-06-06 |
EP1638443A4 (de) | 2008-10-08 |
JP4881156B2 (ja) | 2012-02-22 |
US8912137B2 (en) | 2014-12-16 |
DE602004029680D1 (de) | 2010-12-02 |
EP2308889B1 (de) | 2018-05-23 |
WO2005000095A2 (en) | 2005-01-06 |
ES2354881T3 (es) | 2011-03-18 |
PT1638443E (pt) | 2011-01-25 |
EP1638443A2 (de) | 2006-03-29 |
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Legal Events
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