AU2001233262A1 - Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon - Google Patents

Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon

Info

Publication number
AU2001233262A1
AU2001233262A1 AU2001233262A AU3326201A AU2001233262A1 AU 2001233262 A1 AU2001233262 A1 AU 2001233262A1 AU 2001233262 A AU2001233262 A AU 2001233262A AU 3326201 A AU3326201 A AU 3326201A AU 2001233262 A1 AU2001233262 A1 AU 2001233262A1
Authority
AU
Australia
Prior art keywords
mtsp
cell
sequence
polypeptide
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001233262A
Other languages
English (en)
Inventor
Edwin L. Madison
Edgar O. Ong
Jiunn-Chern Yeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dendreon Corp
Original Assignee
Corvas International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/657,986 external-priority patent/US6797504B1/en
Application filed by Corvas International Inc filed Critical Corvas International Inc
Publication of AU2001233262A1 publication Critical patent/AU2001233262A1/en
Assigned to DENDREON SAN DIEGO LLC reassignment DENDREON SAN DIEGO LLC Request for Assignment Assignors: CORVAS INTERNATIONAL, INC.
Assigned to DENDREON CORPORATION reassignment DENDREON CORPORATION Request for Assignment Assignors: DENDREON SAN DIEGO LLC
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Laminated Bodies (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2001233262A 2000-02-03 2001-02-02 Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon Abandoned AU2001233262A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US17998200P 2000-02-03 2000-02-03
US60179982 2000-02-03
US18354200P 2000-02-18 2000-02-18
US60183542 2000-02-18
US21312400P 2000-06-22 2000-06-22
US60213124 2000-06-22
US22097000P 2000-07-26 2000-07-26
US60220970 2000-07-26
US09/657,986 US6797504B1 (en) 2000-09-08 2000-09-08 Inhibitors of serine protease activity of matriptase or MTSP1
US09657986 2000-09-08
US23484000P 2000-09-22 2000-09-22
US60234840 2000-09-22
PCT/US2001/003471 WO2001057194A2 (en) 2000-02-03 2001-02-02 Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon

Publications (1)

Publication Number Publication Date
AU2001233262A1 true AU2001233262A1 (en) 2001-08-14

Family

ID=27558705

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001233262A Abandoned AU2001233262A1 (en) 2000-02-03 2001-02-02 Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon

Country Status (9)

Country Link
EP (1) EP1252300B1 (de)
JP (1) JP2003521920A (de)
KR (1) KR20020073576A (de)
AT (1) ATE496123T1 (de)
AU (1) AU2001233262A1 (de)
CA (1) CA2396774A1 (de)
DE (1) DE60143880D1 (de)
IL (1) IL150168A0 (de)
WO (1) WO2001057194A2 (de)

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US20030039648A1 (en) 1998-09-16 2003-02-27 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US7037667B1 (en) 1998-06-01 2006-05-02 Agensys, Inc. Tumor antigen useful in diagnosis and therapy of prostate and colon cancer
US6291663B1 (en) * 1999-03-03 2001-09-18 Board Of Trustees Of The University Of Arkansas TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma
KR20020056923A (ko) 1999-11-18 2002-07-10 코르바스 인터내셔날, 인코포레이티드 엔도텔리아제를 암호화하는 핵산, 엔도텔리아제 및 이의용도
EP1280923A2 (de) 2000-04-28 2003-02-05 Millennium Pharmaceuticals, Inc. 14094, ein angehörige der menschlichen trypsin-familie, und dessen verwendungen
US6750034B1 (en) 2000-06-30 2004-06-15 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding human serine protease D-G
WO2002006455A2 (en) * 2000-07-19 2002-01-24 Bayer Aktiengesellschaft Regulation of human airway trypsin protease-like enzyme
US7157596B2 (en) 2000-09-08 2007-01-02 Dendreon Corporation Inhibitors of serine protease activity of matriptase or MTSP1
JP2004337001A (ja) * 2001-01-23 2004-12-02 Mochida Pharmaceut Co Ltd 新規なセリンプロテアーゼｍｐ４９３
US7229774B2 (en) 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
US7332290B2 (en) 2001-08-02 2008-02-19 The Regents Of The University Of Michigan Dectection of AMACR cancer markers in urine
US7700293B2 (en) 2001-08-02 2010-04-20 The Regents Of The University Of Michigan Expression profile of prostate cancer
KR20040111525A (ko) * 2002-04-17 2004-12-31 제넨테크, 인크. 종양의 진단 및 치료 방법 및 이를 위한 조성물
WO2003102135A2 (en) * 2002-05-31 2003-12-11 Schering Aktiengesellschaft Control sequences of the human corin gene
US20060134719A1 (en) * 2002-07-31 2006-06-22 Masayoshi Takeda Novel serine protease
US6977170B2 (en) * 2002-09-06 2005-12-20 Applera Corporation Isolated human hepsin/46 proteins, nucleic acid molecules encoding human hepsin/46 proteins, and uses thereof
US7939304B2 (en) 2002-10-02 2011-05-10 Catalyst Biosciences, Inc. Mutant MT-SP1 proteases with altered substrate specificity or activity
DE10258051A1 (de) * 2002-12-11 2004-07-22 Metagen Pharmaceuticals Gmbh Verwendung von an HAT bindenden Substanzen zur Diagnose und Behandlung des Plattenepithelkarzinoms der Lunge
US7019019B2 (en) 2002-12-23 2006-03-28 Dendreon Corporation Matriptase inhibitors and methods of use
WO2004065599A1 (ja) * 2003-01-24 2004-08-05 Eisai Co., Ltd. Lrp4/Corinドーパミン産生ニューロン増殖前駆細胞マーカー
EP1636356A1 (de) * 2003-06-11 2006-03-22 Schering Aktiengesellschaft Neue modifizierte corin moleküle mit substituierten aktivierungssequenzen und ihre verwendungen
US7476512B2 (en) 2004-02-27 2009-01-13 The General Hospital Corporation Methods of identifying dermal papilla cells
JP5629423B2 (ja) 2004-04-12 2014-11-19 カタリスト バイオサイエンシーズ， インコーポレイテッド 野生型及び変異型ｍｔ−ｓｐ１による、ｖｅｇｆ及びｖｅｇｆ受容体の切断
DE102004023187A1 (de) * 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
JP3996627B2 (ja) 2004-07-22 2007-10-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 Ｌｒｐ４／Ｃｏｒｉｎドーパミン産生ニューロン前駆細胞マーカー
CN101292031A (zh) 2005-08-18 2008-10-22 卫材R&D管理有限公司 多巴胺能神经元增殖祖细胞的标记物Nato3
WO2007047995A2 (en) 2005-10-21 2007-04-26 Catalyst Biosciences, Inc. Modified proteases that inhibit complement activation
NZ573417A (en) * 2006-06-22 2012-01-12 Genentech Inc Methods and compositions for modulating hepsin activation of urokinase-type plasminogen activator
CN101490088B (zh) 2006-06-22 2015-04-08 健泰科生物技术公司 用于靶向hepsin的方法和组合物
KR20150033726A (ko) 2006-07-05 2015-04-01 카탈리스트 바이오사이언시즈, 인코포레이티드 프로테아제 스크리닝 방법 및 이에 의해 확인된 프로테아제
GB0614201D0 (en) * 2006-07-18 2006-08-23 Univ Cardiff Matriptase-2
EP2185933B1 (de) 2007-08-07 2015-10-07 Oxford Biotherapeutics Ltd. Matriptase-protein und verwendungen davon
KR101500670B1 (ko) * 2010-11-02 2015-03-10 인하대학교 산학협력단 암전이를 억제하는 항원 펩타이드, 이를 포함하는 암전이 백신, 암전이 억제 및 치료용 조성물 그리고 암전이 관련 표적물질 및 암전이 억제물질의 스크린 방법
JP6090937B2 (ja) 2011-07-27 2017-03-08 国立大学法人京都大学 新規ドーパミン産生神経前駆細胞マーカー
AR098523A1 (es) 2013-11-25 2016-06-01 Oxford Biotherapeutics Ltd Anticuerpos dirigidos contra matriptasa y composiciones relacionadas
WO2017162659A1 (en) 2016-03-24 2017-09-28 Bayer Pharma Aktiengesellschaft Intracellular hepsin as therapeutic target for the treatment of cancer with centrosome amplification
US20210070823A1 (en) * 2019-04-05 2021-03-11 Azitra Inc Methods and compositions for treating atopic dermatitis with recombinant microorganisms

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Publication number Priority date Publication date Assignee Title
US4952496A (en) 1984-03-30 1990-08-28 Associated Universities, Inc. Cloning and expression of the gene for bacteriophage T7 RNA polymerase
US5401629A (en) 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
JP3488465B2 (ja) 1993-10-28 2004-01-19 ヒューストン・アドバンスド・リサーチ・センター 結合反応を別々に検出する微細加工フロースルー多孔性装置
JPH09149790A (ja) * 1995-09-29 1997-06-10 Suntory Ltd 新規セリンプロテアーゼ
US6203979B1 (en) * 1998-01-16 2001-03-20 Incyte Pharmaceuticals, Inc. Human protease molecules
US5972616A (en) 1998-02-20 1999-10-26 The Board Of Trustees Of The University Of Arkansas TADG-15: an extracellular serine protease overexpressed in breast and ovarian carcinomas
DK1490386T3 (da) * 1998-03-10 2008-12-15 Genentech Inc Nyt polypeptid og nukleinsyrer kodende for dette
US6291663B1 (en) * 1999-03-03 2001-09-18 Board Of Trustees Of The University Of Arkansas TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma
WO2001004141A2 (de) * 1999-07-12 2001-01-18 Merck Patent Gmbh Seripancrin

Also Published As

Publication number Publication date
WO2001057194A2 (en) 2001-08-09
WO2001057194A3 (en) 2002-03-28
EP1252300A2 (de) 2002-10-30
ATE496123T1 (de) 2011-02-15
IL150168A0 (en) 2002-12-01
CA2396774A1 (en) 2001-08-09
JP2003521920A (ja) 2003-07-22
KR20020073576A (ko) 2002-09-27
DE60143880D1 (de) 2011-03-03
EP1252300B1 (de) 2011-01-19

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted