DE69908084T2 - Beschichtung von polymeren - Google Patents
Beschichtung von polymerenInfo
- Publication number
- DE69908084T2 DE69908084T2 DE69908084T DE69908084T DE69908084T2 DE 69908084 T2 DE69908084 T2 DE 69908084T2 DE 69908084 T DE69908084 T DE 69908084T DE 69908084 T DE69908084 T DE 69908084T DE 69908084 T2 DE69908084 T2 DE 69908084T2
- Authority
- DE
- Germany
- Prior art keywords
- lens
- polyionic
- coating
- polyionic material
- contacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001688 coating polymer Polymers 0.000 title 1
- 239000000463 material Substances 0.000 claims description 178
- 229920000831 ionic polymer Polymers 0.000 claims description 120
- 238000000576 coating method Methods 0.000 claims description 96
- 239000011248 coating agent Substances 0.000 claims description 86
- 238000000034 method Methods 0.000 claims description 78
- 239000000243 solution Substances 0.000 claims description 65
- -1 poly(allylamine hydrochloride) Polymers 0.000 claims description 51
- 239000011162 core material Substances 0.000 claims description 36
- 229920000642 polymer Polymers 0.000 claims description 33
- 150000001875 compounds Chemical class 0.000 claims description 22
- 229920000083 poly(allylamine) Polymers 0.000 claims description 21
- 230000008569 process Effects 0.000 claims description 21
- 229920002873 Polyethylenimine Polymers 0.000 claims description 18
- 238000005507 spraying Methods 0.000 claims description 17
- 229920002125 Sokalan® Polymers 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 15
- 238000001035 drying Methods 0.000 claims description 13
- 230000002209 hydrophobic effect Effects 0.000 claims description 13
- 239000004584 polyacrylic acid Substances 0.000 claims description 13
- 238000000465 moulding Methods 0.000 claims description 12
- 229920000867 polyelectrolyte Polymers 0.000 claims description 12
- 229920002518 Polyallylamine hydrochloride Polymers 0.000 claims description 10
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 10
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 239000012487 rinsing solution Substances 0.000 claims description 6
- 229920000767 polyaniline Polymers 0.000 claims description 5
- 238000012546 transfer Methods 0.000 claims description 5
- PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 claims description 4
- 229920002845 Poly(methacrylic acid) Polymers 0.000 claims description 4
- 125000000524 functional group Chemical group 0.000 claims description 4
- 235000012209 glucono delta-lactone Nutrition 0.000 claims description 4
- 229960003681 gluconolactone Drugs 0.000 claims description 4
- 125000000129 anionic group Chemical group 0.000 claims description 3
- 125000002091 cationic group Chemical group 0.000 claims description 3
- 229920000128 polypyrrole Polymers 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 2
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 claims 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 claims 1
- 210000000695 crystalline len Anatomy 0.000 description 144
- 150000003254 radicals Chemical class 0.000 description 16
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 description 13
- 125000004432 carbon atom Chemical group C* 0.000 description 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 10
- 125000003277 amino group Chemical group 0.000 description 9
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 9
- 239000001301 oxygen Substances 0.000 description 9
- 229910052760 oxygen Inorganic materials 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 125000002947 alkylene group Chemical group 0.000 description 8
- 229920001296 polysiloxane Polymers 0.000 description 8
- 238000004381 surface treatment Methods 0.000 description 8
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 7
- 229920002674 hyaluronan Polymers 0.000 description 7
- 229960003160 hyaluronic acid Drugs 0.000 description 7
- 230000005660 hydrophilic surface Effects 0.000 description 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 7
- 230000001965 increasing effect Effects 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- 125000000217 alkyl group Chemical group 0.000 description 6
- 239000012634 fragment Substances 0.000 description 6
- 239000007921 spray Substances 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 239000011521 glass Substances 0.000 description 5
- 239000001257 hydrogen Substances 0.000 description 5
- 229910052739 hydrogen Inorganic materials 0.000 description 5
- 239000000758 substrate Substances 0.000 description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 4
- 239000001110 calcium chloride Substances 0.000 description 4
- 235000011148 calcium chloride Nutrition 0.000 description 4
- 229910001628 calcium chloride Inorganic materials 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 239000013256 coordination polymer Substances 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- 238000007654 immersion Methods 0.000 description 4
- 150000002596 lactones Chemical class 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 230000035699 permeability Effects 0.000 description 4
- 238000009832 plasma treatment Methods 0.000 description 4
- 229920000447 polyanionic polymer Polymers 0.000 description 4
- 238000006116 polymerization reaction Methods 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 125000001424 substituent group Chemical group 0.000 description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 3
- 125000005529 alkyleneoxy group Chemical group 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 238000003618 dip coating Methods 0.000 description 3
- 238000012377 drug delivery Methods 0.000 description 3
- 239000000975 dye Substances 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 150000002894 organic compounds Chemical class 0.000 description 3
- 229920005862 polyol Polymers 0.000 description 3
- 150000003077 polyols Chemical class 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 239000011550 stock solution Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 2
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 2
- 125000003342 alkenyl group Chemical group 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 2
- 230000010261 cell growth Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 210000004087 cornea Anatomy 0.000 description 2
- 125000004966 cyanoalkyl group Chemical group 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 2
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 2
- 229940023490 ophthalmic product Drugs 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 description 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 description 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 description 1
- 125000006528 (C2-C6) alkyl group Chemical group 0.000 description 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 1
- RIWRBSMFKVOJMN-UHFFFAOYSA-N 2-methyl-1-phenylpropan-2-ol Chemical compound CC(C)(O)CC1=CC=CC=C1 RIWRBSMFKVOJMN-UHFFFAOYSA-N 0.000 description 1
- BESKSSIEODQWBP-UHFFFAOYSA-N 3-tris(trimethylsilyloxy)silylpropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C BESKSSIEODQWBP-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 239000004971 Cross linker Substances 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 239000005058 Isophorone diisocyanate Substances 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 125000004423 acyloxy group Chemical group 0.000 description 1
- 239000003732 agents acting on the eye Substances 0.000 description 1
- 125000003302 alkenyloxy group Chemical group 0.000 description 1
- 125000005195 alkyl amino carbonyloxy group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 125000004103 aminoalkyl group Chemical group 0.000 description 1
- 150000003868 ammonium compounds Chemical group 0.000 description 1
- 210000002159 anterior chamber Anatomy 0.000 description 1
- 230000003373 anti-fouling effect Effects 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000001045 blue dye Substances 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 229920006317 cationic polymer Polymers 0.000 description 1
- 125000003636 chemical group Chemical group 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000002322 conducting polymer Substances 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000000572 ellipsometry Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- IIQWTZQWBGDRQG-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate;isocyanic acid Chemical compound N=C=O.CCOC(=O)C(C)=C IIQWTZQWBGDRQG-UHFFFAOYSA-N 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 239000003966 growth inhibitor Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical group 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 230000005661 hydrophobic surface Effects 0.000 description 1
- 150000002440 hydroxy compounds Chemical class 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- NIMLQBUJDJZYEJ-UHFFFAOYSA-N isophorone diisocyanate Chemical compound CC1(C)CC(N=C=O)CC(C)(CN=C=O)C1 NIMLQBUJDJZYEJ-UHFFFAOYSA-N 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000000644 isotonic solution Substances 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 1
- 229960000907 methylthioninium chloride Drugs 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000010399 physical interaction Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000009718 spray deposition Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/10—Optical coatings produced by application to, or surface treatment of, optical elements
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Eyeglasses (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
- Electrotherapy Devices (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Apparatuses And Processes For Manufacturing Resistors (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US531798A | 1998-01-09 | 1998-01-09 | |
| US19960998A | 1998-11-25 | 1998-11-25 | |
| PCT/EP1999/000058 WO1999035520A1 (en) | 1998-01-09 | 1999-01-07 | Coating of polymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69908084D1 DE69908084D1 (de) | 2003-06-26 |
| DE69908084T2 true DE69908084T2 (de) | 2003-11-27 |
Family
ID=26674205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69908084T Expired - Lifetime DE69908084T2 (de) | 1998-01-09 | 1999-01-07 | Beschichtung von polymeren |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1046068B1 (https=) |
| JP (1) | JP4634603B2 (https=) |
| KR (1) | KR20010033969A (https=) |
| CN (1) | CN1287620A (https=) |
| AR (1) | AR014269A1 (https=) |
| AT (1) | ATE241151T1 (https=) |
| AU (1) | AU745472B2 (https=) |
| BR (1) | BR9906836A (https=) |
| CA (1) | CA2314078C (https=) |
| DE (1) | DE69908084T2 (https=) |
| DK (1) | DK1046068T3 (https=) |
| ES (1) | ES2200496T3 (https=) |
| HU (1) | HUP0100553A2 (https=) |
| IL (1) | IL136516A0 (https=) |
| NO (1) | NO325172B1 (https=) |
| PL (1) | PL341346A1 (https=) |
| TW (1) | TW403841B (https=) |
| WO (1) | WO1999035520A1 (https=) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451871B1 (en) | 1998-11-25 | 2002-09-17 | Novartis Ag | Methods of modifying surface characteristics |
| AR027348A1 (es) | 2000-02-04 | 2003-03-26 | Novartis Ag | Proceso para recubrir una superficie |
| EP1280613A4 (en) * | 2000-04-14 | 2003-08-27 | Virginia Tech Intell Prop | SELF-BUILDING THIN FILM COATING TO IMPROVE THE BIO-COMPATIBILITY OF MATERIALS |
| US6689480B2 (en) * | 2000-05-10 | 2004-02-10 | Toray Industries, Inc. | Surface-treated plastic article and method of surface treatment |
| JP4834916B2 (ja) * | 2000-05-10 | 2011-12-14 | 東レ株式会社 | 表面処理プラスチック成形品 |
| EP1299753B1 (en) * | 2000-05-30 | 2004-05-12 | Novartis AG | Coated articles |
| US6589665B2 (en) | 2000-05-30 | 2003-07-08 | Novartis Ag | Coated articles |
| CA2415871A1 (en) * | 2000-08-24 | 2002-02-28 | Novartis Ag | Process for surface modifying substrates and modified substrates resulting therefrom |
| US6774178B2 (en) | 2001-01-05 | 2004-08-10 | Novartis Ag | Tinted, high Dk ophthalmic molding and a method for making same |
| JP4152193B2 (ja) | 2001-04-27 | 2008-09-17 | アイセンス・アクチエンゲゼルシャフト | 血中グルコース濃度計測装置 |
| US6815074B2 (en) | 2001-05-30 | 2004-11-09 | Novartis Ag | Polymeric materials for making contact lenses |
| US6827966B2 (en) | 2001-05-30 | 2004-12-07 | Novartis Ag | Diffusion-controllable coatings on medical device |
| US6811805B2 (en) | 2001-05-30 | 2004-11-02 | Novatis Ag | Method for applying a coating |
| US6689478B2 (en) * | 2001-06-21 | 2004-02-10 | Corning Incorporated | Polyanion/polycation multilayer film for DNA immobilization |
| TW200407367A (en) * | 2001-11-13 | 2004-05-16 | Novartis Ag | Method for modifying the surface of biomedical articles |
| US7402318B2 (en) * | 2001-11-14 | 2008-07-22 | Novartis Ag | Medical devices having antimicrobial coatings thereon |
| AR038269A1 (es) * | 2002-01-09 | 2005-01-12 | Novartis Ag | Articulos polimericos que tienen un recubrimiento lubrico, y metodo para fabricarlos |
| US20030215626A1 (en) * | 2002-03-22 | 2003-11-20 | Hiller Jeri?Apos;Ann | Nanoporous coatings |
| US7863038B2 (en) * | 2002-03-29 | 2011-01-04 | Board Of Regents, The University Of Texas System | Implantable biosensor from stratified nanostructured membranes |
| US7799467B2 (en) | 2002-04-08 | 2010-09-21 | Massachusetts Institute Of Technology | Solid polymer electrolytes from ethylene oxide-containing, layer-by-layer assembled films |
| US7101947B2 (en) | 2002-06-14 | 2006-09-05 | Florida State University Research Foundation, Inc. | Polyelectrolyte complex films for analytical and membrane separation of chiral compounds |
| US6926965B2 (en) | 2002-09-11 | 2005-08-09 | Novartis Ag | LbL-coated medical device and method for making the same |
| US6896926B2 (en) * | 2002-09-11 | 2005-05-24 | Novartis Ag | Method for applying an LbL coating onto a medical device |
| US20050038329A1 (en) * | 2002-11-20 | 2005-02-17 | Morris Carol Ann | Methods and kits for assays of rapid screening of diabetes |
| US8172395B2 (en) * | 2002-12-03 | 2012-05-08 | Novartis Ag | Medical devices having antimicrobial coatings thereon |
| US20050008676A1 (en) * | 2002-12-19 | 2005-01-13 | Yongxing Qiu | Medical devices having antimicrobial coatings thereon |
| WO2004089321A1 (en) * | 2003-04-09 | 2004-10-21 | Unilever Plc | Hair treatment compositions |
| US7251893B2 (en) * | 2003-06-03 | 2007-08-07 | Massachusetts Institute Of Technology | Tribological applications of polyelectrolyte multilayers |
| US8481017B2 (en) | 2004-02-23 | 2013-07-09 | Florida State University Research Foundation, Inc. | Thin films for controlled protein interaction |
| AU2005244258B2 (en) | 2004-04-09 | 2010-07-01 | Monsanto Technology Llc | Compositions and methods for control of insect infestations in plants |
| JP4809022B2 (ja) * | 2005-09-05 | 2011-11-02 | Ｈｏｙａ株式会社 | コンタクトレンズ材料の製造方法およびソフトコンタクトレンズの製造方法 |
| PL1931397T3 (pl) | 2005-10-05 | 2009-08-31 | Essity Hygiene & Health Ab | Wyrób absorpcyjny zawierający obszary hydrofilowe i hydrofobowe |
| US8044112B2 (en) | 2006-03-30 | 2011-10-25 | Novartis Ag | Method for applying a coating onto a silicone hydrogel lens |
| US9052442B2 (en) | 2006-10-30 | 2015-06-09 | Novartis Ag | Method for applying a coating onto a silicone hydrogel lens |
| US7968650B2 (en) * | 2006-10-31 | 2011-06-28 | Johnson & Johnson Vision Care, Inc. | Polymeric compositions comprising at least one volume excluding polymer |
| CN101568354B (zh) | 2006-12-21 | 2013-05-22 | 诺瓦提斯公司 | 涂覆生物医学器件的方法 |
| CA2676294C (en) | 2007-02-09 | 2014-10-21 | Novartis Ag | Cross-linkable polyionic coatings for contact lenses |
| EP2115499B1 (en) * | 2007-02-26 | 2015-11-11 | Novartis AG | Method for imparting hydrogel contact lenses with desired properties |
| WO2009115477A2 (en) | 2008-03-18 | 2009-09-24 | Novartis Ag | Coating process for ophthalmic lenses |
| CA2787888C (en) | 2010-02-16 | 2016-04-19 | Toray Industries, Inc. | Low water content soft lens for eye, and method for producing the same |
| FR2960167B1 (fr) | 2010-05-21 | 2013-02-08 | Centre Nat Rech Scient | Procede d'obtention de couches minces |
| US8480227B2 (en) | 2010-07-30 | 2013-07-09 | Novartis Ag | Silicone hydrogel lenses with water-rich surfaces |
| WO2012112624A2 (en) | 2011-02-15 | 2012-08-23 | Svaya Nanotechnologies, Inc. | Methods and materials for functional polyionic species and deposition thereof |
| US9778488B2 (en) | 2011-08-17 | 2017-10-03 | Toray Industries, Inc. | Medical device and method for producing the same |
| US9632212B2 (en) | 2011-08-17 | 2017-04-25 | Toray Industries, Inc. | Medical device and method for producing the same |
| WO2013024800A1 (ja) * | 2011-08-17 | 2013-02-21 | 東レ株式会社 | 低含水性軟質デバイスおよびその製造方法 |
| JP6003653B2 (ja) * | 2011-08-17 | 2016-10-05 | 東レ株式会社 | 医療デバイスおよびその製造方法 |
| CN105739120B (zh) * | 2011-08-17 | 2019-03-15 | 东丽株式会社 | 医疗设备、涂布溶液的组合和医疗设备的制造方法 |
| JP6236782B2 (ja) * | 2011-08-17 | 2017-11-29 | 東レ株式会社 | 低含水性軟質眼用レンズおよびその製造方法 |
| WO2013052927A2 (en) | 2011-10-07 | 2013-04-11 | Svaya Nanotechnologies, Inc. | Broadband solar control film |
| HUE029018T2 (en) | 2011-10-12 | 2017-02-28 | Novartis Ag | A method for producing UV absorbing contact lenses by coating |
| CN104704145B (zh) * | 2012-09-17 | 2017-06-09 | 伊士曼化工公司 | 用于提高叠层过程的控制和效率的方法、材料和设备 |
| HUE031702T2 (en) | 2012-12-17 | 2017-07-28 | Novartis Ag | A method for producing improved UV absorbing ophthalmic lenses |
| CN104871035B (zh) | 2012-12-20 | 2018-01-30 | 3M创新有限公司 | 制备包括层层自组装层的多层光学膜的方法以及制品 |
| CN105229090A (zh) | 2013-05-31 | 2016-01-06 | 3M创新有限公司 | 逐层自组装包含光吸收或光稳定化合物的高分子电解质的方法和制品 |
| EP3062979B1 (en) * | 2013-10-31 | 2018-08-29 | Novartis AG | Method for producing ophthalmic lenses |
| JP6230880B2 (ja) * | 2013-11-11 | 2017-11-15 | 株式会社シード | 親水性の表面を有するシリコーン系軟質性眼用レンズを製造する方法 |
| HUE038809T2 (hu) | 2013-12-17 | 2018-11-28 | Novartis Ag | Térhálósított hidrofíl bevonattal ellátott szilikon hidrogél lencse |
| EP2944604A1 (en) | 2014-05-16 | 2015-11-18 | Université de Strasbourg | Preparation of coatings containing at least one in-plane oriented layer of anisotropic shaped objects |
| MY183678A (en) | 2014-08-26 | 2021-03-08 | Alcon Inc | Method for applying stable coating on silicone hydrogel contact lenses |
| US11109957B2 (en) | 2014-09-22 | 2021-09-07 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US10159562B2 (en) | 2014-09-22 | 2018-12-25 | Kevin J. Cady | Intraocular pseudophakic contact lenses and related systems and methods |
| US10299910B2 (en) | 2014-09-22 | 2019-05-28 | Kevin J. Cady | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US10945832B2 (en) | 2014-09-22 | 2021-03-16 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US12447007B2 (en) | 2014-09-22 | 2025-10-21 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US11938018B2 (en) | 2014-09-22 | 2024-03-26 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens (IOPCL) for treating age-related macular degeneration (AMD) or other eye disorders |
| US9453949B2 (en) | 2014-12-15 | 2016-09-27 | Eastman Chemical Company | Electromagnetic energy-absorbing optical product and method for making |
| US9891347B2 (en) | 2014-12-15 | 2018-02-13 | Eastman Chemical Company | Electromagnetic energy-absorbing optical product and method for making |
| US9817166B2 (en) | 2014-12-15 | 2017-11-14 | Eastman Chemical Company | Electromagnetic energy-absorbing optical product and method for making |
| US9891357B2 (en) | 2014-12-15 | 2018-02-13 | Eastman Chemical Company | Electromagnetic energy-absorbing optical product and method for making |
| KR102604468B1 (ko) | 2015-12-15 | 2023-11-22 | 알콘 인코포레이티드 | 실리콘 하이드로겔 콘택트 렌즈 상에 안정한 코팅을 적용하기 위한 방법 |
| CN106581786A (zh) * | 2016-11-22 | 2017-04-26 | 华南理工大学 | 一种功能性补片及其制备方法与应用 |
| US10338287B2 (en) | 2017-08-29 | 2019-07-02 | Southwall Technologies Inc. | Infrared-rejecting optical products having pigmented coatings |
| US11747532B2 (en) | 2017-09-15 | 2023-09-05 | Southwall Technologies Inc. | Laminated optical products and methods of making them |
| CN117492228A (zh) | 2017-12-13 | 2024-02-02 | 爱尔康公司 | 周抛和月抛水梯度接触镜片 |
| US10627555B2 (en) | 2018-04-09 | 2020-04-21 | Southwall Technologies Inc. | Selective light-blocking optical products having a neutral reflection |
| US10613261B2 (en) | 2018-04-09 | 2020-04-07 | Southwall Technologies Inc. | Selective light-blocking optical products having a neutral reflection |
| TWI690424B (zh) * | 2018-10-29 | 2020-04-11 | 優你康光學股份有限公司 | 具有聚合物多層膜的隱形眼鏡之製備方法 |
| US11795320B2 (en) * | 2019-09-20 | 2023-10-24 | Bausch + Lomb Ireland Limited | Grafted polymer and use thereof |
| CN111544653A (zh) * | 2020-05-04 | 2020-08-18 | 湖北省百纳慧喻生物科技有限公司 | 一种适应多维临床需求的仿生叠层组织工程皮肤及其制备方法 |
| GB202008098D0 (en) | 2020-05-29 | 2020-07-15 | Uea Enterprises Ltd | A method of coating an ocular prosthetic device and other prosthetics |
| EP4328659A1 (en) | 2021-04-19 | 2024-02-28 | National Institute for Materials Science | Soft ophthalmic lens and method for manufacturing same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168112A (en) * | 1978-01-05 | 1979-09-18 | Polymer Technology Corporation | Contact lens with a hydrophilic, polyelectrolyte complex coating and method for forming same |
| JPH01158412A (ja) * | 1986-12-26 | 1989-06-21 | Daicel Chem Ind Ltd | コンタクトレンズ用洗浄保存液 |
| JP2578127B2 (ja) * | 1987-08-20 | 1997-02-05 | ト−メ−産業株式会社 | コンタクトレンズ用溶液 |
| US5336797A (en) * | 1992-12-30 | 1994-08-09 | Bausch & Lomb Incorporated | Siloxane macromonomers |
| AU7061594A (en) * | 1993-06-18 | 1995-01-17 | Polymer Technology Corporation | Contact lens solution containing peo and cationic cellulose |
| US5518767A (en) * | 1993-07-01 | 1996-05-21 | Massachusetts Institute Of Technology | Molecular self-assembly of electrically conductive polymers |
| JPH07266443A (ja) * | 1994-03-30 | 1995-10-17 | Hoya Corp | ソフトコンタクトレンズの製造方法 |
| US5700559A (en) * | 1994-12-16 | 1997-12-23 | Advanced Surface Technology | Durable hydrophilic surface coatings |
-
1999
- 1999-01-07 AU AU22784/99A patent/AU745472B2/en not_active Ceased
- 1999-01-07 DE DE69908084T patent/DE69908084T2/de not_active Expired - Lifetime
- 1999-01-07 WO PCT/EP1999/000058 patent/WO1999035520A1/en not_active Ceased
- 1999-01-07 PL PL99341346A patent/PL341346A1/xx not_active Application Discontinuation
- 1999-01-07 CN CN99802027A patent/CN1287620A/zh active Pending
- 1999-01-07 HU HU0100553A patent/HUP0100553A2/hu unknown
- 1999-01-07 JP JP2000527849A patent/JP4634603B2/ja not_active Expired - Lifetime
- 1999-01-07 AR ARP990100047A patent/AR014269A1/es unknown
- 1999-01-07 AT AT99902524T patent/ATE241151T1/de not_active IP Right Cessation
- 1999-01-07 IL IL13651699A patent/IL136516A0/xx unknown
- 1999-01-07 KR KR1020007007554A patent/KR20010033969A/ko not_active Withdrawn
- 1999-01-07 TW TW088100168A patent/TW403841B/zh not_active IP Right Cessation
- 1999-01-07 BR BR9906836-2A patent/BR9906836A/pt not_active IP Right Cessation
- 1999-01-07 EP EP99902524A patent/EP1046068B1/en not_active Expired - Lifetime
- 1999-01-07 DK DK99902524T patent/DK1046068T3/da active
- 1999-01-07 CA CA002314078A patent/CA2314078C/en not_active Expired - Fee Related
- 1999-01-07 ES ES99902524T patent/ES2200496T3/es not_active Expired - Lifetime
-
2000
- 2000-07-06 NO NO20003486A patent/NO325172B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010033969A (ko) | 2001-04-25 |
| DK1046068T3 (da) | 2003-09-01 |
| BR9906836A (pt) | 2000-10-17 |
| EP1046068B1 (en) | 2003-05-21 |
| CA2314078C (en) | 2009-09-08 |
| JP4634603B2 (ja) | 2011-02-16 |
| NO20003486D0 (no) | 2000-07-06 |
| ES2200496T3 (es) | 2004-03-01 |
| AU2278499A (en) | 1999-07-26 |
| NO20003486L (no) | 2000-09-05 |
| AR014269A1 (es) | 2001-02-07 |
| TW403841B (en) | 2000-09-01 |
| HUP0100553A2 (hu) | 2001-06-28 |
| CA2314078A1 (en) | 1999-07-15 |
| NO325172B1 (no) | 2008-02-11 |
| DE69908084D1 (de) | 2003-06-26 |
| ATE241151T1 (de) | 2003-06-15 |
| IL136516A0 (en) | 2001-06-14 |
| WO1999035520A1 (en) | 1999-07-15 |
| AU745472B2 (en) | 2002-03-21 |
| EP1046068A1 (en) | 2000-10-25 |
| JP2002501211A (ja) | 2002-01-15 |
| PL341346A1 (en) | 2001-04-09 |
| CN1287620A (zh) | 2001-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69908084T2 (de) | Beschichtung von polymeren | |
| DE60311584T2 (de) | Verfahren zur lagenweisen beschichtung eines medizinischen gegenstandes | |
| DE60316315T2 (de) | Lbl-beschichtete kontaktlinsen und verfahren zu deren herstellung | |
| DE60114767T2 (de) | Verfahren zur beschichtung einer oberfläche | |
| US7566746B2 (en) | Biomedical devices having improved surface characteristics | |
| DE60304904T2 (de) | Verfahren zur herstellung vonmedizinprodukten mit antimikrobiellen beschichtungen | |
| DE60103278T2 (de) | Beschichtete gegenstände | |
| DE60223589T2 (de) | Verfahren zum modifizieren der oberfläche von biomedizinischen gegenständen | |
| DE69912352T2 (de) | Biomedizinische Vorrichtung mit Feuchthaltemittelbeschichtungen | |
| DE60016449T2 (de) | Beschichtungsverfahren | |
| DE69533460T2 (de) | Sauerstoffdurchlässige Kontaktlinse mit hydrophiler Oberfläche und Verfahren zur Herstellung derselben | |
| DE69706852T2 (de) | Copolymere mit amphiphilen segmenten und kontrollierter morphologie; opthalmische produkte und kontaktlinsen auf basis diesen copolymeren | |
| DE69605780T2 (de) | Perfluoroalkylether enthaltendes polysiloxan and dessen herstellung und verwendung | |
| DE60114808T2 (de) | Oberflächenbehandlung von medizinischer vorrichtung | |
| DE69935457T2 (de) | Perfluoroalkylpolyetherpolymere für ophthalmische anwendungen | |
| DE60126697T2 (de) | Verfahren zur Herstellung eines Materials für Okularlinsen mit hydrophiler Oberfläche | |
| DE3727044A1 (de) | Massen fuer kontaktlinsen und biokompatible koerper | |
| DE60117373T2 (de) | Verwendung von ophthalmischen zusammensetzungen mit niedriger ionenstärke | |
| DE60102076T2 (de) | Reaktive polymere | |
| MXPA00006435A (en) | Coating of polymers | |
| Bozukov | Aminated polyelectrolytes: advanced concepts for their modification and application |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN |