DE69840166D1 - Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes - Google Patents
Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzesInfo
- Publication number
- DE69840166D1 DE69840166D1 DE69840166T DE69840166T DE69840166D1 DE 69840166 D1 DE69840166 D1 DE 69840166D1 DE 69840166 T DE69840166 T DE 69840166T DE 69840166 T DE69840166 T DE 69840166T DE 69840166 D1 DE69840166 D1 DE 69840166D1
- Authority
- DE
- Germany
- Prior art keywords
- reagent
- magnetic field
- magnetism
- reaction mixture
- binding test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 3
- 230000027455 binding Effects 0.000 title abstract 2
- 230000005389 magnetism Effects 0.000 title 1
- 239000011541 reaction mixture Substances 0.000 abstract 3
- 239000012491 analyte Substances 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
- Y10S977/838—Magnetic property of nanomaterial
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
- Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/92—Detection of biochemical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
- Y10S977/953—Detector using nanostructure
- Y10S977/96—Of magnetic property
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/857,440 US5998224A (en) | 1997-05-16 | 1997-05-16 | Magnetically assisted binding assays utilizing a magnetically responsive reagent |
| PCT/US1998/009945 WO1998052043A1 (en) | 1997-05-16 | 1998-05-15 | Magnetically assisted binding assays utilizing a magnetically responsive reagent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69840166D1 true DE69840166D1 (de) | 2008-12-11 |
Family
ID=25326006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69840166T Expired - Lifetime DE69840166D1 (de) | 1997-05-16 | 1998-05-15 | Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5998224A (https=) |
| EP (2) | EP0981749B1 (https=) |
| JP (4) | JP4237267B2 (https=) |
| AT (1) | ATE412898T1 (https=) |
| CA (1) | CA2290018C (https=) |
| DE (1) | DE69840166D1 (https=) |
| ES (2) | ES2316163T3 (https=) |
| WO (1) | WO1998052043A1 (https=) |
Families Citing this family (123)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19753851A1 (de) * | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Vorrichtung zum kapillaren Flüssigkeitstransport |
| JP5122705B2 (ja) * | 1999-01-25 | 2013-01-16 | ミナーヴァ・バイオテクノロジーズ・コーポレーション | 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出 |
| EP1198712A2 (de) * | 1999-02-17 | 2002-04-24 | Kilian Hennes | Verfahren zum darstellen von biologisch aktivierten induktivitätsändernden partikeln sowie vorrichtung dafür |
| WO2001018235A2 (en) * | 1999-09-09 | 2001-03-15 | Eichrom Technologies, Inc. | Lateral flow device with metal oxide indicator and assay method employing same |
| US7537938B2 (en) | 2000-04-28 | 2009-05-26 | Monogram Biosciences, Inc. | Biomarker detection in circulating cells |
| US7015047B2 (en) * | 2001-01-26 | 2006-03-21 | Aviva Biosciences Corporation | Microdevices having a preferential axis of magnetization and uses thereof |
| US7811768B2 (en) * | 2001-01-26 | 2010-10-12 | Aviva Biosciences Corporation | Microdevice containing photorecognizable coding patterns and methods of using and producing the same |
| FR2826882B1 (fr) * | 2001-07-09 | 2003-09-12 | Bio Merieux | Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede |
| US7169577B2 (en) * | 2001-07-27 | 2007-01-30 | Surface Logix, Inc. | Cell isolation and screening device and method of using same |
| US7285412B2 (en) * | 2001-07-27 | 2007-10-23 | Surface Logix Inc. | Device for magnetic immobilization of cells |
| US7169578B2 (en) * | 2001-07-27 | 2007-01-30 | Surface Logix, Inc. | Cell isolation and screening device and method of using same |
| US10022078B2 (en) | 2004-07-13 | 2018-07-17 | Dexcom, Inc. | Analyte sensor |
| AU2003215402A1 (en) * | 2002-02-22 | 2003-09-09 | Purdue Research Foundation | Fe/au nanoparticles and methods |
| US8697029B2 (en) * | 2002-04-18 | 2014-04-15 | The Regents Of The University Of Michigan | Modulated physical and chemical sensors |
| CA2491093A1 (en) * | 2002-06-28 | 2004-01-08 | Purdue Research Foundation | Magnetic nanomaterials and methods for detection of biological materials |
| US7601491B2 (en) | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
| CN1280428C (zh) * | 2003-05-19 | 2006-10-18 | 清华大学 | 一种基于微小颗粒的生物芯片系统及其应用 |
| FR2855613B1 (fr) * | 2003-05-26 | 2005-08-19 | Biocytex | Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres |
| US7402398B2 (en) | 2003-07-17 | 2008-07-22 | Monogram Biosciences, Inc. | Measuring receptor homodimerization |
| WO2005019470A2 (en) | 2003-08-11 | 2005-03-03 | Monogram Biosciences, Inc. | Detecting and profiling molecular complexes |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US20050282182A1 (en) * | 2003-12-30 | 2005-12-22 | Universal Bio Research Co., Ltd. | Reaction vessel and reaction apparatus comprising three-dimensional particle array |
| JP2005315677A (ja) * | 2004-04-28 | 2005-11-10 | Canon Inc | 検出装置および検出方法 |
| DE102004033811A1 (de) * | 2004-07-12 | 2006-02-02 | Salama, Abdulgabar, Prof. Dr. | Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel |
| US8989833B2 (en) | 2004-07-13 | 2015-03-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20060024776A1 (en) * | 2004-08-02 | 2006-02-02 | Mcmillian Ray | Magnetic particle capture of whole intact organisms from clinical samples |
| AU2005299590B2 (en) | 2004-10-27 | 2010-09-16 | Cepheid | Closed-system multi-stage nucleic acid amplification reactions |
| US7939267B2 (en) * | 2004-11-04 | 2011-05-10 | Laboratory Corporation Of America Holdings | Detection of activation of endothelial cells as surrogate marker for angiogenesis |
| EP1859330B1 (en) | 2005-01-28 | 2012-07-04 | Duke University | Apparatuses and methods for manipulating droplets on a printed circuit board |
| DE602006000724T2 (de) | 2005-02-05 | 2009-04-23 | Samsung Electronics Co., Ltd., Suwon | Sensorschalter und seine Verwendung in einem Nachweisverfahren |
| US7781228B2 (en) | 2005-04-07 | 2010-08-24 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| US7300631B2 (en) | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
| US7263874B2 (en) * | 2005-06-08 | 2007-09-04 | Bioscale, Inc. | Methods and apparatus for determining properties of a fluid |
| US20060281104A1 (en) * | 2005-06-13 | 2006-12-14 | Macevicz Stephen C | Leuco dye particles and uses thereof |
| US20070020699A1 (en) * | 2005-07-19 | 2007-01-25 | Idexx Laboratories, Inc. | Lateral flow assay and device using magnetic particles |
| US20070059782A1 (en) * | 2005-09-13 | 2007-03-15 | Graham Henry A | Magnetic particle tagged blood bank reagents and techniques |
| US9488665B2 (en) * | 2005-09-13 | 2016-11-08 | Chrome Red Technologies, Llc | Magnetic particle tagged reagents and techniques |
| US20070166730A1 (en) * | 2006-01-19 | 2007-07-19 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| EP2000484B1 (en) * | 2006-03-27 | 2011-11-30 | Tokyo Institute of Technology | Process for producing polymer-coated ferromagnetic particle, and polymer-coated ferromagnetic particle |
| US8492168B2 (en) * | 2006-04-18 | 2013-07-23 | Advanced Liquid Logic Inc. | Droplet-based affinity assays |
| US9476856B2 (en) * | 2006-04-13 | 2016-10-25 | Advanced Liquid Logic, Inc. | Droplet-based affinity assays |
| US20140193807A1 (en) | 2006-04-18 | 2014-07-10 | Advanced Liquid Logic, Inc. | Bead manipulation techniques |
| US7727723B2 (en) * | 2006-04-18 | 2010-06-01 | Advanced Liquid Logic, Inc. | Droplet-based pyrosequencing |
| US7901947B2 (en) | 2006-04-18 | 2011-03-08 | Advanced Liquid Logic, Inc. | Droplet-based particle sorting |
| US8809068B2 (en) | 2006-04-18 | 2014-08-19 | Advanced Liquid Logic, Inc. | Manipulation of beads in droplets and methods for manipulating droplets |
| US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
| US10078078B2 (en) | 2006-04-18 | 2018-09-18 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
| US8637324B2 (en) | 2006-04-18 | 2014-01-28 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
| US8900828B2 (en) | 2006-05-01 | 2014-12-02 | Cepheid | Methods and apparatus for sequential amplification reactions |
| US9675972B2 (en) | 2006-05-09 | 2017-06-13 | Advanced Liquid Logic, Inc. | Method of concentrating beads in a droplet |
| US8119352B2 (en) * | 2006-06-20 | 2012-02-21 | Cepheld | Multi-stage amplification reactions by control of sequence replication times |
| JP5277165B2 (ja) * | 2006-07-24 | 2013-08-28 | ベクトン・ディキンソン・アンド・カンパニー | 分析粒子凝集およびイメージング装置および方法 |
| EP2573562A3 (en) | 2007-02-09 | 2013-10-30 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods employing magnetic beads |
| US9068977B2 (en) * | 2007-03-09 | 2015-06-30 | The Regents Of The University Of Michigan | Non-linear rotation rates of remotely driven particles and uses thereof |
| US8927260B2 (en) * | 2007-03-12 | 2015-01-06 | Fabrico Technology, Inc. | Anaylte detection system using an oscillating magnetic field |
| WO2009032863A2 (en) | 2007-09-04 | 2009-03-12 | Advanced Liquid Logic, Inc. | Droplet actuator with improved top substrate |
| US9631244B2 (en) | 2007-10-17 | 2017-04-25 | Advanced Liquid Logic, Inc. | Reagent storage on a droplet actuator |
| CA2709928A1 (en) | 2007-12-23 | 2009-07-09 | Advanced Liquid Logic, Inc. | Droplet actuator configurations and methods of conducting droplet operations |
| US7927561B2 (en) * | 2008-01-10 | 2011-04-19 | Becton, Dickinson And Company | Rapid particle detection assay |
| CA2711956A1 (en) | 2008-01-17 | 2009-07-23 | The Regents Of The University Of California | Integrated magnetic field generation and detection platform |
| WO2009126649A2 (en) * | 2008-04-07 | 2009-10-15 | Life Bioscience, Inc. | Method of providing particles having biological-binding areas for biological applications |
| US8852952B2 (en) | 2008-05-03 | 2014-10-07 | Advanced Liquid Logic, Inc. | Method of loading a droplet actuator |
| US8926065B2 (en) | 2009-08-14 | 2015-01-06 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods |
| WO2011057197A2 (en) | 2009-11-06 | 2011-05-12 | Advanced Liquid Logic, Inc. | Integrated droplet actuator for gel electrophoresis and molecular analysis |
| EP2516669B1 (en) | 2009-12-21 | 2016-10-12 | Advanced Liquid Logic, Inc. | Enzyme assays on a droplet actuator |
| US9233370B2 (en) | 2010-08-05 | 2016-01-12 | Abbott Point Of Care Inc. | Magnetic immunosensor and method of use |
| US11402375B2 (en) | 2010-08-05 | 2022-08-02 | Abbott Point Of Care Inc. | Magnetic immunosensor with trench configuration and method of use |
| WO2012019109A1 (en) | 2010-08-05 | 2012-02-09 | Abbott Point Of Care Inc. | Oscillating immunoassay method and device |
| CN103118785B (zh) | 2010-08-05 | 2015-11-25 | 雅培医护站股份有限公司 | 使用易感磁微珠捕获的免疫测定方法和装置 |
| US8846331B2 (en) | 2010-08-27 | 2014-09-30 | The Regents Of The University Of Michigan | Asynchronous magnetic bead rotation sensing systems and methods |
| US20120077184A1 (en) * | 2010-09-28 | 2012-03-29 | Starkdx Incorporated | Electromagnetic multiplex assay biosensor |
| WO2012142179A2 (en) | 2011-04-11 | 2012-10-18 | The Regents Of The University Of Michigan | Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells |
| WO2012154745A2 (en) | 2011-05-09 | 2012-11-15 | Advanced Liquid Logic, Inc. | Microfluidic feedback using impedance detection |
| WO2013009927A2 (en) | 2011-07-11 | 2013-01-17 | Advanced Liquid Logic, Inc. | Droplet actuators and techniques for droplet-based assays |
| WO2013016413A2 (en) | 2011-07-25 | 2013-01-31 | Advanced Liquid Logic Inc | Droplet actuator apparatus and system |
| JP2013088164A (ja) * | 2011-10-14 | 2013-05-13 | Hitachi High-Technologies Corp | 自動分析装置 |
| WO2013078216A1 (en) | 2011-11-21 | 2013-05-30 | Advanced Liquid Logic Inc | Glucose-6-phosphate dehydrogenase assays |
| US9797817B2 (en) | 2012-05-03 | 2017-10-24 | The Regents Of The University Of Michigan | Multi-mode separation for target detection |
| EP2664914A1 (en) * | 2012-05-16 | 2013-11-20 | Koninklijke Philips N.V. | Magnetically assisted processing of a medium |
| EP2867645B1 (en) | 2012-06-27 | 2019-06-05 | Advanced Liquid Logic, Inc. | Techniques and droplet actuator designs for reducing bubble formation |
| JP6217936B2 (ja) * | 2012-07-06 | 2017-10-25 | 凸版印刷株式会社 | 被検物質の検出システム |
| JP6120518B2 (ja) * | 2012-10-10 | 2017-04-26 | 公益財団法人かずさDna研究所 | 簡易測定器具 |
| US20160296945A1 (en) | 2013-03-15 | 2016-10-13 | Ancera, Inc. | Systems and methods for active particle separation |
| US20160299132A1 (en) | 2013-03-15 | 2016-10-13 | Ancera, Inc. | Systems and methods for bead-based assays in ferrofluids |
| JP6420055B2 (ja) * | 2013-03-29 | 2018-11-07 | 積水メディカル株式会社 | イムノクロマト用着色粒子及びこれを用いた診断用イムノクロマト試薬 |
| US9983110B2 (en) | 2013-11-04 | 2018-05-29 | The Regents Of The University Of Michigan | Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes |
| EP2883961B8 (en) * | 2013-12-12 | 2017-09-27 | Altratech Limited | A nucleic acid analysis method and apparatus |
| CN106102898B (zh) * | 2014-03-14 | 2019-05-28 | 株式会社岛津制作所 | 磁性体颗粒的操作方法及磁性体颗粒操作用装置 |
| US10665377B2 (en) | 2014-05-05 | 2020-05-26 | 3D Glass Solutions, Inc. | 2D and 3D inductors antenna and transformers fabricating photoactive substrates |
| JP6350654B2 (ja) * | 2014-05-23 | 2018-07-04 | 株式会社島津製作所 | 磁性体粒子の操作方法 |
| WO2016013115A1 (ja) * | 2014-07-25 | 2016-01-28 | 株式会社 リージャー | 希釈生体試料成分の分析方法 |
| KR101860543B1 (ko) * | 2015-01-09 | 2018-05-24 | 한양대학교 에리카산학협력단 | 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법 |
| US11285490B2 (en) | 2015-06-26 | 2022-03-29 | Ancera, Llc | Background defocusing and clearing in ferrofluid-based capture assays |
| JP6865466B2 (ja) * | 2015-06-26 | 2021-04-28 | 株式会社カワノラボ | 分散質分析方法、および分析装置 |
| WO2017052506A1 (en) * | 2015-09-22 | 2017-03-30 | Halliburton Energy Services, Inc. | Optical device window cleaning system |
| US10070533B2 (en) | 2015-09-30 | 2018-09-04 | 3D Glass Solutions, Inc. | Photo-definable glass with integrated electronics and ground plane |
| KR102479144B1 (ko) | 2016-02-25 | 2022-12-20 | 3디 글래스 솔루션즈 인코포레이티드 | 3d 커패시터 및 커패시터 어레이 제작용 광활성 기재 |
| US12165809B2 (en) | 2016-02-25 | 2024-12-10 | 3D Glass Solutions, Inc. | 3D capacitor and capacitor array fabricating photoactive substrates |
| WO2017177171A1 (en) | 2016-04-08 | 2017-10-12 | 3D Glass Solutions, Inc. | Methods of fabricating photosensitive substrates suitable for optical coupler |
| KR101994370B1 (ko) * | 2016-08-24 | 2019-06-28 | 주식회사 제놉시 | 항체 및 자성 나노 입자가 결합된 전도성 고분자를 포함하는 혈중 암세포 검출 및 회수용 자성 나노 구조체 |
| EP3529595B1 (en) | 2016-10-20 | 2023-05-31 | Quantum Diamond Technologies Inc. | Methods and apparatus for magnetic particle analysis using wide-field diamond magnetic imaging |
| US10590409B2 (en) * | 2016-12-06 | 2020-03-17 | Wisconsin Alumni Research Foundation | Method and device for disaggregation via heterogeneous particles |
| WO2018119367A1 (en) | 2016-12-23 | 2018-06-28 | Quantum Diamond Technologies Inc. | Methods and apparatus for magnetic multi-bead assays |
| US11101532B2 (en) | 2017-04-28 | 2021-08-24 | 3D Glass Solutions, Inc. | RF circulator |
| AU2018297035B2 (en) | 2017-07-07 | 2021-02-25 | 3D Glass Solutions, Inc. | 2D and 3D RF lumped element devices for RF system in a package photoactive glass substrates |
| CA3070975A1 (en) | 2017-07-31 | 2019-02-07 | Quantum Diamond Technologies Inc. | Methods and apparatus for sample measurement |
| US10854946B2 (en) | 2017-12-15 | 2020-12-01 | 3D Glass Solutions, Inc. | Coupled transmission line resonate RF filter |
| AU2018399638B2 (en) | 2018-01-04 | 2021-09-02 | 3D Glass Solutions, Inc. | Impedance matching conductive structure for high efficiency RF circuits |
| JP7272348B2 (ja) * | 2018-03-20 | 2023-05-12 | 住友電気工業株式会社 | 微小粒子計測装置 |
| WO2019199470A1 (en) | 2018-04-10 | 2019-10-17 | 3D Glass Solutions, Inc. | Rf integrated power condition capacitor |
| US10903545B2 (en) | 2018-05-29 | 2021-01-26 | 3D Glass Solutions, Inc. | Method of making a mechanically stabilized radio frequency transmission line device |
| WO2019235270A1 (ja) * | 2018-06-08 | 2019-12-12 | 国立研究開発法人産業技術総合研究所 | 標的物質検出方法及び標的物質検出キット |
| AU2019344542B2 (en) | 2018-09-17 | 2022-02-24 | 3D Glass Solutions, Inc. | High efficiency compact slotted antenna with a ground plane |
| AU2019416327B2 (en) | 2018-12-28 | 2021-12-09 | 3D Glass Solutions, Inc. | Annular capacitor RF, microwave and MM wave systems |
| EP3903347A4 (en) | 2018-12-28 | 2022-03-09 | 3D Glass Solutions, Inc. | HETEROGENE INTEGRATION FOR HF, MICROWAVE AND MM WAVE SYSTEMS ON PHOTOACTIVE GLASS SUBSTRATES |
| KR20210147040A (ko) | 2019-04-05 | 2021-12-06 | 3디 글래스 솔루션즈 인코포레이티드 | 유리 기반의 빈 기판 집적 도파관 디바이스 |
| CA3136642C (en) | 2019-04-18 | 2023-01-03 | 3D Glass Solutions, Inc. | High efficiency die dicing and release |
| JP7051004B2 (ja) * | 2019-05-09 | 2022-04-08 | 三菱電機株式会社 | 磁性摩耗粉量測定装置及び機械装置 |
| JP2023516817A (ja) | 2020-04-17 | 2023-04-20 | スリーディー グラス ソリューションズ,インク | 広帯域誘導 |
| WO2021230821A1 (en) * | 2020-05-12 | 2021-11-18 | National University Of Singapore | A method for virus and biomarker detection |
| RU200521U1 (ru) * | 2020-05-26 | 2020-10-28 | Алексей Николаевич Темников | Портативный сканер-дисплей магнитного поля |
| EP4252907A1 (en) * | 2022-03-30 | 2023-10-04 | Blink AG | A method for arranging microspheres in a non-aqueous liquid phase |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3985649A (en) * | 1974-11-25 | 1976-10-12 | Eddelman Roy T | Ferromagnetic separation process and material |
| US4070246A (en) * | 1976-04-09 | 1978-01-24 | Abbott Laboratories | Reactive matrices |
| GB8401368D0 (en) * | 1984-01-19 | 1984-02-22 | Amersham Int Plc | Assay method |
| US5076950A (en) * | 1985-12-20 | 1991-12-31 | Syntex (U.S.A.) Inc. | Magnetic composition for particle separation |
| JPH0614051B2 (ja) * | 1986-02-10 | 1994-02-23 | 株式会社ニッテク | 抗原―抗体不溶化担体の選別方法 |
| US4960691A (en) * | 1986-09-29 | 1990-10-02 | Abbott Laboratories | Chromatographic test strip for determining ligands or receptors |
| JPS63108264A (ja) * | 1986-10-25 | 1988-05-13 | Nippon Telegr & Teleph Corp <Ntt> | 磁気免疫測定方法および該方法を実施するために使用する検査試薬片 |
| US5236824A (en) * | 1988-04-26 | 1993-08-17 | Nippon Telegraph And Telephone Corporation | Laser magnetic immunoassay method and method by a magnetophoresis apparatus therefor |
| JP2599175B2 (ja) * | 1988-04-26 | 1997-04-09 | 日本電信電話株式会社 | レーザ磁気免疫測定方法及び測定装置並びにレーザ磁気免疫測定に用いる超常磁性体標識体及びその製造方法 |
| US5145784A (en) * | 1988-05-04 | 1992-09-08 | Cambridge Biotech Corporation | Double capture assay method employing a capillary flow device |
| US5108933A (en) * | 1988-09-16 | 1992-04-28 | Immunicon Corporation | Manipulation of colloids for facilitating magnetic separations |
| US5252459A (en) * | 1988-09-23 | 1993-10-12 | Abbott Laboratories | Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles |
| CA1335181C (en) * | 1988-10-11 | 1995-04-11 | R. Alan Hardwick | System for selective cell separation from cell concentrate |
| TW221493B (https=) * | 1990-07-10 | 1994-03-01 | Cardiovascular Diagnostics Inc | |
| JPH0552849A (ja) * | 1991-08-28 | 1993-03-02 | Terumo Corp | 検体の特異的検出および特異的分離方法 |
| CA2129042C (en) * | 1992-03-20 | 2002-02-19 | Thomas E. Rohr | Magnetically assisted binding assays using magnetically-labeled binding members |
| US5445970A (en) * | 1992-03-20 | 1995-08-29 | Abbott Laboratories | Magnetically assisted binding assays using magnetically labeled binding members |
| US5445971A (en) * | 1992-03-20 | 1995-08-29 | Abbott Laboratories | Magnetically assisted binding assays using magnetically labeled binding members |
| WO1993019371A1 (en) * | 1992-03-20 | 1993-09-30 | Abbott Laboratories | Determination of binding affinity using magneticaly-labeled binding members |
| AU677780B2 (en) * | 1992-05-01 | 1997-05-08 | Trustees Of The University Of Pennsylvania, The | Microfabricated detection structures |
| US5358659A (en) * | 1992-07-09 | 1994-10-25 | Xerox Corporation | Magnetic materials with single-domain and multidomain crystallites and a method of preparation |
| US5322756A (en) * | 1992-07-09 | 1994-06-21 | Xerox Corporation | Magnetic fluids and method of preparation |
| WO1994020855A1 (en) * | 1993-03-04 | 1994-09-15 | Sapidyne, Inc. | Assay flow apparatus and method |
| US5374531A (en) * | 1993-03-22 | 1994-12-20 | Zynaxis, Inc. | Immunoassay for determination of cells |
| FR2708348B1 (fr) * | 1993-07-28 | 1995-10-06 | Stago Diagnostica | Procédé de dosage d'une substance immunologique au moyen de particules de latex magnétiques et de particules non-magnétiques. |
| GB9409333D0 (en) * | 1994-05-10 | 1994-06-29 | Palmer Richard F | Analytical method and device for use therein |
| US5656429A (en) * | 1994-10-03 | 1997-08-12 | Adelman; Lonnie W. | Polynucleotide and protein analysis method using magnetizable moieties |
| FR2732116B1 (fr) * | 1995-03-21 | 1997-05-09 | Bio Merieux | Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique |
| JPH08304399A (ja) * | 1995-04-28 | 1996-11-22 | Mitsubishi Chem Corp | 磁性体粒子の分離方法およびそれを用いた免疫分析方法 |
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1997
- 1997-05-16 US US08/857,440 patent/US5998224A/en not_active Expired - Lifetime
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1998
- 1998-05-15 ES ES98921225T patent/ES2316163T3/es not_active Expired - Lifetime
- 1998-05-15 AT AT98921225T patent/ATE412898T1/de not_active IP Right Cessation
- 1998-05-15 WO PCT/US1998/009945 patent/WO1998052043A1/en not_active Ceased
- 1998-05-15 CA CA2290018A patent/CA2290018C/en not_active Expired - Fee Related
- 1998-05-15 EP EP98921225A patent/EP0981749B1/en not_active Expired - Lifetime
- 1998-05-15 ES ES07118773T patent/ES2378782T3/es not_active Expired - Lifetime
- 1998-05-15 EP EP07118773A patent/EP1881325B1/en not_active Expired - Lifetime
- 1998-05-15 JP JP54956998A patent/JP4237267B2/ja not_active Expired - Lifetime
- 1998-05-15 DE DE69840166T patent/DE69840166D1/de not_active Expired - Lifetime
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- 2007-06-04 JP JP2007148109A patent/JP4324212B2/ja not_active Expired - Fee Related
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2009
- 2009-04-27 JP JP2009107323A patent/JP4806457B2/ja not_active Expired - Lifetime
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|---|---|
| ES2378782T3 (es) | 2012-04-17 |
| JP4806457B2 (ja) | 2011-11-02 |
| JP2009204617A (ja) | 2009-09-10 |
| US5998224A (en) | 1999-12-07 |
| JP2008003083A (ja) | 2008-01-10 |
| JP2002504993A (ja) | 2002-02-12 |
| WO1998052043A1 (en) | 1998-11-19 |
| JP4237267B2 (ja) | 2009-03-11 |
| EP1881325A1 (en) | 2008-01-23 |
| CA2290018A1 (en) | 1998-11-19 |
| CA2290018C (en) | 2011-07-19 |
| ES2316163T3 (es) | 2009-04-01 |
| JP2011257413A (ja) | 2011-12-22 |
| ATE412898T1 (de) | 2008-11-15 |
| EP0981749B1 (en) | 2008-10-29 |
| JP4324212B2 (ja) | 2009-09-02 |
| EP0981749A1 (en) | 2000-03-01 |
| EP1881325B1 (en) | 2012-01-11 |
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