DE69838066T3 - Behandlung der diabetes mit thiazolidindione und sulphonylurea - Google Patents
Behandlung der diabetes mit thiazolidindione und sulphonylurea Download PDFInfo
- Publication number
- DE69838066T3 DE69838066T3 DE69838066T DE69838066T DE69838066T3 DE 69838066 T3 DE69838066 T3 DE 69838066T3 DE 69838066 T DE69838066 T DE 69838066T DE 69838066 T DE69838066 T DE 69838066T DE 69838066 T3 DE69838066 T3 DE 69838066T3
- Authority
- DE
- Germany
- Prior art keywords
- compound
- pharmaceutically acceptable
- methyl
- thiazolidine
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- BOVGTQGAOIONJV-BETUJISGSA-N 1-[(3ar,6as)-3,3a,4,5,6,6a-hexahydro-1h-cyclopenta[c]pyrrol-2-yl]-3-(4-methylphenyl)sulfonylurea Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)NN1C[C@H]2CCC[C@H]2C1 BOVGTQGAOIONJV-BETUJISGSA-N 0.000 claims description 12
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9715306A GB9715306D0 (en) | 1997-07-18 | 1997-07-18 | Novel method of treatment |
| GB9715306 | 1997-07-18 | ||
| PCT/GB1998/002109 WO1999003476A1 (en) | 1997-07-18 | 1998-07-16 | Treatment of diabetes with thiazolidinedione and sulphonylurea |
| EP98935126A EP0998291B2 (en) | 1997-07-18 | 1998-07-16 | Treatment of diabetes with thiazolidinedione and sulphonylurea |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE69838066D1 DE69838066D1 (de) | 2007-08-23 |
| DE69838066T2 DE69838066T2 (de) | 2008-03-20 |
| DE69838066T3 true DE69838066T3 (de) | 2012-03-29 |
Family
ID=10816177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69838066T Expired - Lifetime DE69838066T3 (de) | 1997-07-18 | 1998-07-16 | Behandlung der diabetes mit thiazolidindione und sulphonylurea |
Country Status (40)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| EP1832291A3 (en) * | 1999-07-13 | 2009-11-04 | Medicure Inc. | use of pyridoxal phosphate for the treatment of diabetes and related complications |
| EP1897547A1 (en) * | 1999-07-13 | 2008-03-12 | Medicure Inc. | Use of pyridoxal phosphate derivatives for the treatment of diabetes and related complications |
| US6586438B2 (en) | 1999-11-03 | 2003-07-01 | Bristol-Myers Squibb Co. | Antidiabetic formulation and method |
| US20010036479A1 (en) | 2000-01-14 | 2001-11-01 | Gillian Cave | Glyburide composition |
| US7964216B2 (en) | 2001-01-12 | 2011-06-21 | Sun Pharma Advanced Research Company Limited | Spaced drug delivery system |
| WO2005041962A1 (en) * | 2003-10-31 | 2005-05-12 | Takeda Pharmaceutical Company Limited | Solid preparation comprising an insulin sensitizer, an insulin secretagogue and a polyoxyethylene sorbitan fatty acid ester |
| JP2008019169A (ja) * | 2004-10-25 | 2008-01-31 | Osaka Univ | 新規ｐｐａｒ調節剤およびそのスクリーニング方法 |
| AU2006328328B2 (en) | 2005-12-22 | 2012-08-30 | Takeda Pharmaceutical Company Limited | Solid preparation containing an insulin sensitizer |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| JPS5697277A (en) * | 1980-01-07 | 1981-08-05 | Takeda Chem Ind Ltd | Thiazolidine derivative |
| JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| US4582839A (en) * | 1984-03-21 | 1986-04-15 | Takeda Chemical Industries, Ltd. | 2,4-thiazolidinediones |
| CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
| US4812570A (en) * | 1986-07-24 | 1989-03-14 | Takeda Chemical Industries, Ltd. | Method for producing thiazolidinedione derivatives |
| ES2137915T3 (es) * | 1987-09-04 | 2000-01-01 | Beecham Group Plc | Derivados de tiazolidindiona sustituida. |
| US4791125A (en) * | 1987-12-02 | 1988-12-13 | Pfizer Inc. | Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents |
| WO1989008651A1 (en) * | 1988-03-08 | 1989-09-21 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| FI904414A0 (fi) * | 1988-03-08 | 1990-09-07 | Pfizer | Tiazolidindion-hypoglykemiskt verkande aemnen. |
| WO1991007107A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
| JPH04210683A (ja) * | 1990-12-06 | 1992-07-31 | Terumo Corp | チアゾリジン−２，４−ジオン誘導体およびこれを含有する糖尿病合併症治療薬 |
| US5183823A (en) * | 1991-04-11 | 1993-02-02 | Takeda Chemical Industries, Ltd. | Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents |
| DE69211450T2 (de) * | 1991-08-16 | 1996-12-05 | Sandoz Ag | Inhalator zur Verabreichung von pulverförmigen Substanzen |
| JPH06510286A (ja) * | 1991-08-26 | 1994-11-17 | ファルマシア・アンド・アップジョン・カンパニー | ３−グアニジノプロピオン酸およびピオグリタゾン、グリベンクラミドまたはグリメピリドを含有する医薬組成物 |
| GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
| TW438587B (en) * | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| US5859037A (en) * | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
-
1997
- 1997-07-18 GB GB9715306A patent/GB9715306D0/en active Pending
-
1998
- 1998-07-15 DZ DZ980174A patent/DZ2564A1/xx active
- 1998-07-16 KR KR1020007000513A patent/KR100680667B1/ko not_active Expired - Lifetime
- 1998-07-16 JP JP2000502775A patent/JP2001510158A/ja not_active Withdrawn
- 1998-07-16 NZ NZ501256A patent/NZ501256A/xx not_active IP Right Cessation
- 1998-07-16 HU HU0003634A patent/HU229119B1/hu unknown
- 1998-07-16 NZ NZ515555A patent/NZ515555A/xx not_active IP Right Cessation
- 1998-07-16 UA UA2000010215A patent/UA70302C2/uk unknown
- 1998-07-16 PT PT98935126T patent/PT998291E/pt unknown
- 1998-07-16 PL PL375989A patent/PL199125B1/pl unknown
- 1998-07-16 BR BR9810904-9A patent/BR9810904A/pt not_active Application Discontinuation
- 1998-07-16 NZ NZ520652A patent/NZ520652A/en not_active IP Right Cessation
- 1998-07-16 WO PCT/GB1998/002109 patent/WO1999003476A1/en active IP Right Grant
- 1998-07-16 ES ES98935126T patent/ES2290989T5/es not_active Expired - Lifetime
- 1998-07-16 CA CA2297115A patent/CA2297115C/en not_active Expired - Lifetime
- 1998-07-16 AP APAP/P/2000/001734A patent/AP1318A/en active
- 1998-07-16 CN CN98807221A patent/CN1264302A/zh active Pending
- 1998-07-16 IL IL13404598A patent/IL134045A0/xx unknown
- 1998-07-16 TR TR2000/00135T patent/TR200000135T2/xx unknown
- 1998-07-16 MA MA25173A patent/MA26522A1/fr unknown
- 1998-07-16 PL PL98338127A patent/PL338127A1/xx not_active Application Discontinuation
- 1998-07-16 OA OA1200000014A patent/OA11632A/en unknown
- 1998-07-16 DK DK98935126.7T patent/DK0998291T4/da active
- 1998-07-16 DE DE69838066T patent/DE69838066T3/de not_active Expired - Lifetime
- 1998-07-16 SK SK60-2000A patent/SK287823B6/sk not_active IP Right Cessation
- 1998-07-16 CZ CZ20000173A patent/CZ302668B6/cs not_active IP Right Cessation
- 1998-07-16 EA EA200000141A patent/EA003303B1/ru not_active IP Right Cessation
- 1998-07-16 SI SI9830892T patent/SI0998291T2/sl unknown
- 1998-07-16 PE PE1998000631A patent/PE99799A1/es not_active Application Discontinuation
- 1998-07-16 SK SK89-2005A patent/SK288053B6/sk not_active IP Right Cessation
- 1998-07-16 AT AT98935126T patent/ATE366577T1/de active
- 1998-07-16 ID IDW20000074A patent/ID24198A/id unknown
- 1998-07-16 EP EP98935126A patent/EP0998291B2/en not_active Expired - Lifetime
- 1998-07-16 AU AU84487/98A patent/AU743269B2/en not_active Expired
- 1998-07-17 CO CO98040748A patent/CO4940422A1/es unknown
- 1998-07-17 ZA ZA9806365A patent/ZA986365B/xx unknown
- 1998-07-17 MY MYPI98003290A patent/MY138246A/en unknown
- 1998-07-17 UY UY25103A patent/UY25103A1/es not_active IP Right Cessation
- 1998-07-17 TW TW087111768A patent/TW586926B/zh not_active IP Right Cessation
- 1998-07-17 AR ARP980103516A patent/AR016768A1/es not_active Application Discontinuation
- 1998-07-20 IN IN2089DE1998 patent/IN189035B/en unknown
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1999
- 1999-06-18 AR ARP990102953A patent/AR019331A2/es unknown
-
2000
- 2000-01-17 NO NO20000229A patent/NO326356B1/no not_active IP Right Cessation
- 2000-02-08 BG BG104139A patent/BG64892B1/bg unknown
-
2005
- 2005-04-21 JP JP2005123586A patent/JP2005247865A/ja active Pending
-
2007
- 2007-09-27 CY CY20071101241T patent/CY1107745T1/el unknown
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Inventor name: BUCKINGHAM, ROBIN EDWIN, HARLOW ESSEX CM19 5AW, GB Inventor name: SMITH, STEPHEN ALISTAIR, HARLOW, ESSEX CM19 5A, GB |
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| 8363 | Opposition against the patent | ||
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