DE69828276D1 - Neue zyklische diaminverbindungen und heilmittel das diese enthält - Google Patents
Neue zyklische diaminverbindungen und heilmittel das diese enthältInfo
- Publication number
- DE69828276D1 DE69828276D1 DE69828276T DE69828276T DE69828276D1 DE 69828276 D1 DE69828276 D1 DE 69828276D1 DE 69828276 T DE69828276 T DE 69828276T DE 69828276 T DE69828276 T DE 69828276T DE 69828276 D1 DE69828276 D1 DE 69828276D1
- Authority
- DE
- Germany
- Prior art keywords
- optionally substituted
- lower alkyl
- alkyl group
- integer
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- -1 DIAMINE COMPOUNDS Chemical class 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 125000003107 substituted aryl group Chemical group 0.000 abstract 3
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 1
- 102000001494 Sterol O-Acyltransferase Human genes 0.000 abstract 1
- 108010054082 Sterol O-acyltransferase Proteins 0.000 abstract 1
- RGJOEKWQDUBAIZ-UHFFFAOYSA-N coenzime A Natural products OC1C(OP(O)(O)=O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005516 coenzyme A Substances 0.000 abstract 1
- 229940093530 coenzyme a Drugs 0.000 abstract 1
- KDTSHFARGAKYJN-UHFFFAOYSA-N dephosphocoenzyme A Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 KDTSHFARGAKYJN-UHFFFAOYSA-N 0.000 abstract 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 150000003457 sulfones Chemical class 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14989297 | 1997-05-26 | ||
JP14989297 | 1997-05-26 | ||
PCT/JP1998/002300 WO1998054153A1 (fr) | 1997-05-26 | 1998-05-26 | Nouveaux composes de diamine cycliques et medicament contenant ces composes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69828276D1 true DE69828276D1 (de) | 2005-01-27 |
DE69828276T2 DE69828276T2 (de) | 2005-12-15 |
Family
ID=15484915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69828276T Expired - Lifetime DE69828276T2 (de) | 1997-05-26 | 1998-05-26 | Neue cyclische Diaminverbindungen und Heilmittel das diese enthält |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0987254B1 (de) |
JP (1) | JP3614865B2 (de) |
KR (1) | KR100549804B1 (de) |
CN (1) | CN1118457C (de) |
AT (1) | ATE285402T1 (de) |
AU (1) | AU728151B2 (de) |
CA (1) | CA2290744C (de) |
CZ (1) | CZ297451B6 (de) |
DE (1) | DE69828276T2 (de) |
ES (1) | ES2235328T3 (de) |
HU (1) | HUP0002294A3 (de) |
ID (1) | ID23377A (de) |
NO (1) | NO315045B1 (de) |
NZ (1) | NZ501156A (de) |
PT (1) | PT987254E (de) |
RU (1) | RU2207341C2 (de) |
SK (1) | SK284891B6 (de) |
TW (1) | TW589308B (de) |
WO (1) | WO1998054153A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6452008B2 (en) | 1998-02-25 | 2002-09-17 | Sumitomo Pharmaceuticals Company, Limited | Pyridone derivatives and process for preparing the same |
WO1999043659A1 (fr) * | 1998-02-25 | 1999-09-02 | Sumitomo Pharmaceuticals Co., Ltd. | Derives de pyridone et leur procede de fabrication |
DE60007748T2 (de) | 1999-06-28 | 2004-11-25 | Fuji Photo Film Co., Ltd., Minami-Ashigara | Benzimidazolderivate und sie enthaltende medikamente |
AU776803B2 (en) | 1999-06-30 | 2004-09-23 | Fuji Photo Film Co., Ltd. | Benzimidazole compounds and medicaments comprising the same |
WO2001004110A1 (fr) * | 1999-07-07 | 2001-01-18 | Fuji Photo Film Co., Ltd. | Composes de benzimidazole |
JP4242765B2 (ja) * | 2001-08-22 | 2009-03-25 | 興和株式会社 | 血管壁選択的なacat阻害剤 |
US20060165605A1 (en) * | 2001-12-28 | 2006-07-27 | Ye-Mon Chen | Process to regenerate fcc spent catalyst |
PT1566381E (pt) * | 2002-11-28 | 2009-11-19 | Kowa Co | Processo para produção de 1-[2-(benzimidazol-2-il-tio)- etil]piperazina ou seus sais |
ES2287574T3 (es) * | 2002-12-05 | 2007-12-16 | Cv Therapeutics, Inc. | Compuestos de piperacina sustituidos y su utilizacion como inhibidores de la oxidacion de acidos grasos. |
WO2004052861A1 (ja) * | 2002-12-12 | 2004-06-24 | Kowa Co., Ltd. | ヒドロキシアルキル環状ジアミン化合物 |
MY140618A (en) * | 2003-02-28 | 2009-12-31 | Kowa Co | Method for preparing acid addition salts of polyacidic basic compounds |
CN1784395A (zh) * | 2003-05-07 | 2006-06-07 | 埃科特莱茵药品有限公司 | 哌嗪-烷基-脲基衍生物 |
JP4806566B2 (ja) * | 2003-05-28 | 2011-11-02 | 興和株式会社 | 環状ジアミン誘導体又はその塩の製造法 |
MY140849A (en) | 2003-07-07 | 2010-01-29 | Kowa Co | 2, 4-bis (trifluoroethoxy) pyridine compound and drug containing the compound |
KR20060111898A (ko) | 2003-08-29 | 2006-10-30 | 교와 가부시키가이샤 | 지질-풍부-플라크의 안정화 방법 및 파열 예방방법 |
AU2004293013B2 (en) | 2003-11-19 | 2011-04-28 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
US7163944B2 (en) | 2004-01-26 | 2007-01-16 | Kowa Co., Ltd. | Cyclic diamine compound and pharmaceutical containing the same |
WO2006003974A1 (ja) * | 2004-06-30 | 2006-01-12 | Kowa Co., Ltd. | 環状ジアミン誘導体の製造法 |
CA2576170A1 (en) * | 2004-08-16 | 2006-03-02 | The Procter & Gamble Company | 2-(amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof |
CA2585623C (en) | 2004-10-27 | 2012-06-05 | Daiichi Sankyo Company Limited | Ortho-substituted benzene derivatives |
TW200619204A (en) * | 2004-12-10 | 2006-06-16 | Kowa Co | Method for reduction, stabilization and prevention of rupture of lipid rich plaque |
FR2920769B1 (fr) * | 2007-09-06 | 2009-10-30 | Galderma Res & Dev | Nouveaux derives de n-phenyl acetamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant |
FR2920774B1 (fr) * | 2007-09-06 | 2009-10-30 | Galderma Res & Dev | Nouveaux derives de n-phenul acatamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contentant |
FR2920770B1 (fr) * | 2007-09-06 | 2009-10-30 | Galderma Res & Dev | Nouveaux derives de phenylurees, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant |
JP5291979B2 (ja) | 2008-04-24 | 2013-09-18 | 株式会社フジクラ | 圧力センサ及びその製造方法と、該圧力センサを備えた電子部品 |
US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
JPWO2011081118A1 (ja) * | 2009-12-29 | 2013-05-13 | 興和株式会社 | 経口投与用医薬組成物 |
EP2520299A1 (de) | 2009-12-29 | 2012-11-07 | Kowa Co., Ltd. | Feste pharmazeutische zusammensetzung zur oralen verabreichung |
EP2573081B1 (de) * | 2010-05-19 | 2017-07-12 | Kowa Company Ltd. | Prophylaktisches und/oder therapeutisches mittel für nicht-alkoholische steatohepatitis |
US20160052898A1 (en) * | 2013-03-20 | 2016-02-25 | Bayer Pharma Aktiengesellschaft | Novel compounds |
CN105693524A (zh) * | 2014-11-28 | 2016-06-22 | 浙江省化工研究院有限公司 | 一种硝基化合物的制备方法 |
WO2018097149A1 (ja) * | 2016-11-24 | 2018-05-31 | 帝人ファーマ株式会社 | スルフィド化合物の製造方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3629208A (en) * | 1969-06-18 | 1971-12-21 | Monsanto Co | N-aminoalkyl thiazolesulfenamides as vulcanization accelerators |
CA2003283A1 (en) * | 1988-12-05 | 1990-06-05 | C. Anne Higley | Imidazoles for the treatment of atherosclerosis |
WO1992007825A1 (en) * | 1990-11-05 | 1992-05-14 | Taisho Pharmaceutical Co., Ltd. | Phenol derivative |
US5721266A (en) * | 1993-05-28 | 1998-02-24 | Warner-Lambert Company | Substituted imidazolinyl-imidazolines as antagonists of SH-2 binding and therapeutic uses thereof |
US5596001A (en) * | 1993-10-25 | 1997-01-21 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)quinoline derivatves |
JP4191269B2 (ja) * | 1996-05-17 | 2008-12-03 | 興和株式会社 | 新規なアニリド化合物及びこれを含有する医薬 |
ATE297900T1 (de) * | 1997-03-25 | 2005-07-15 | Kowa Co | Anilidverbindungen und medikamente, die diese enthalten |
ES2262248T3 (es) * | 1997-11-14 | 2006-11-16 | Kowa Company. Ltd. | Nuevos compuestos amida y medicamente que los contienen. |
-
1998
- 1998-05-26 EP EP98921809A patent/EP0987254B1/de not_active Expired - Lifetime
- 1998-05-26 KR KR1019997010894A patent/KR100549804B1/ko not_active IP Right Cessation
- 1998-05-26 HU HU0002294A patent/HUP0002294A3/hu unknown
- 1998-05-26 RU RU99128053/04A patent/RU2207341C2/ru not_active IP Right Cessation
- 1998-05-26 ID IDW991669A patent/ID23377A/id unknown
- 1998-05-26 TW TW087108155A patent/TW589308B/zh not_active IP Right Cessation
- 1998-05-26 ES ES98921809T patent/ES2235328T3/es not_active Expired - Lifetime
- 1998-05-26 AT AT98921809T patent/ATE285402T1/de active
- 1998-05-26 DE DE69828276T patent/DE69828276T2/de not_active Expired - Lifetime
- 1998-05-26 CN CN98805498A patent/CN1118457C/zh not_active Expired - Fee Related
- 1998-05-26 SK SK1582-99A patent/SK284891B6/sk not_active IP Right Cessation
- 1998-05-26 NZ NZ501156A patent/NZ501156A/en not_active IP Right Cessation
- 1998-05-26 WO PCT/JP1998/002300 patent/WO1998054153A1/ja active IP Right Grant
- 1998-05-26 PT PT98921809T patent/PT987254E/pt unknown
- 1998-05-26 JP JP50047199A patent/JP3614865B2/ja not_active Expired - Fee Related
- 1998-05-26 CA CA002290744A patent/CA2290744C/en not_active Expired - Fee Related
- 1998-05-26 AU AU74512/98A patent/AU728151B2/en not_active Ceased
- 1998-05-26 CZ CZ0415999A patent/CZ297451B6/cs not_active IP Right Cessation
-
1999
- 1999-11-25 NO NO19995783A patent/NO315045B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0987254A4 (de) | 2000-09-13 |
AU7451298A (en) | 1998-12-30 |
CN1118457C (zh) | 2003-08-20 |
KR100549804B1 (ko) | 2006-02-08 |
WO1998054153A1 (fr) | 1998-12-03 |
ATE285402T1 (de) | 2005-01-15 |
SK284891B6 (sk) | 2006-02-02 |
EP0987254A1 (de) | 2000-03-22 |
DE69828276T2 (de) | 2005-12-15 |
SK158299A3 (en) | 2001-02-12 |
TW589308B (en) | 2004-06-01 |
KR20010012926A (ko) | 2001-02-26 |
CN1258283A (zh) | 2000-06-28 |
HUP0002294A3 (en) | 2001-10-29 |
AU728151B2 (en) | 2001-01-04 |
NO995783D0 (no) | 1999-11-25 |
NO315045B1 (no) | 2003-06-30 |
JP3614865B2 (ja) | 2005-01-26 |
CA2290744C (en) | 2009-12-22 |
CA2290744A1 (en) | 1998-12-03 |
CZ415999A3 (cs) | 2000-05-17 |
ES2235328T3 (es) | 2005-07-01 |
PT987254E (pt) | 2005-04-29 |
NZ501156A (en) | 2002-02-01 |
EP0987254B1 (de) | 2004-12-22 |
CZ297451B6 (cs) | 2006-12-13 |
ID23377A (id) | 2000-04-20 |
HUP0002294A2 (hu) | 2001-09-28 |
NO995783L (no) | 2000-01-26 |
RU2207341C2 (ru) | 2003-06-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69828276D1 (de) | Neue zyklische diaminverbindungen und heilmittel das diese enthält | |
LV12606A (lv) | Okssiiminoalkanskabes atvasinajumi | |
ATE438624T1 (de) | 2-pyridonderivate mit affinität für den cannabinoid-typ-2-rezeptor | |
FI943561A (fi) | Uudet ainekoostumukset | |
DE69834052D1 (de) | Neue amidverbindungen und medikamente die diese enthalten | |
DE69529619T2 (de) | Pyrimidinylpyrazolderivate | |
ATE314352T1 (de) | Anilide als acat-hemmer | |
ATE109770T1 (de) | Derivate der coffeinsäure und pharmazeutische zusammensetzungen, die sie enthalten. | |
DE69937045D1 (de) | Cyclische amidderivate | |
DE60136464D1 (de) | Neue schwefelverbindungen und intermolekulare verbindungen, die diese als komponente enthalten | |
DE69004598D1 (de) | 6-Amino-6-desoxyfumagillole, ihre Herstellung und ihre Verwendung. | |
DE69830600D1 (de) | Anilidverbindungen und medikamente, die diese enthalten | |
ATE214059T1 (de) | 4,6-di-t-butyl-2,3-dihydrobenzothiophene, die ldl oxidation hemmen | |
DE69319859T2 (de) | Neue tetracyclische verbindungen | |
GR81941B (de) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |