DE69834052D1 - Neue amidverbindungen und medikamente die diese enthalten - Google Patents

Neue amidverbindungen und medikamente die diese enthalten

Info

Publication number
DE69834052D1
DE69834052D1 DE69834052T DE69834052T DE69834052D1 DE 69834052 D1 DE69834052 D1 DE 69834052D1 DE 69834052 T DE69834052 T DE 69834052T DE 69834052 T DE69834052 T DE 69834052T DE 69834052 D1 DE69834052 D1 DE 69834052D1
Authority
DE
Germany
Prior art keywords
group
atom
lower alkyl
alkyl group
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69834052T
Other languages
English (en)
Other versions
DE69834052T2 (de
Inventor
Kimiyuki Shibuya
Toru Miura
Katsumi Kawamine
Yukihiro Sato
Tadaaki Ohgiya
Takahiro Kitamura
Chiyoka Ozaki
Toshiyuki Edano
Mitsuteru Hirata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Application granted granted Critical
Publication of DE69834052D1 publication Critical patent/DE69834052D1/de
Publication of DE69834052T2 publication Critical patent/DE69834052T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69834052T 1997-11-14 1998-11-16 Neue amidverbindungen und medikamente die diese enthalten Expired - Lifetime DE69834052T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP33087797 1997-11-14
JP33087797 1997-11-14
PCT/JP1998/005149 WO1999025712A1 (fr) 1997-11-14 1998-11-16 Nouveaux composes d'amide et medicaments contenant ces derniers

Publications (2)

Publication Number Publication Date
DE69834052D1 true DE69834052D1 (de) 2006-05-18
DE69834052T2 DE69834052T2 (de) 2006-11-02

Family

ID=18237521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69834052T Expired - Lifetime DE69834052T2 (de) 1997-11-14 1998-11-16 Neue amidverbindungen und medikamente die diese enthalten

Country Status (10)

Country Link
EP (1) EP0979823B1 (de)
JP (1) JP4402176B2 (de)
AT (1) ATE321759T1 (de)
AU (1) AU755654C (de)
CA (1) CA2303781A1 (de)
DE (1) DE69834052T2 (de)
ES (1) ES2262248T3 (de)
HU (1) HUP0000729A3 (de)
TW (1) TW580498B (de)
WO (1) WO1999025712A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0987254B1 (de) * 1997-05-26 2004-12-22 Kowa Co., Ltd. Neue zyklische diaminverbindungen und heilmittel das diese enthält
US6969711B2 (en) 1997-05-26 2005-11-29 Kowa Company, Ltd. Cyclic diamine compounds and medicine containing the same
DE60007748T2 (de) 1999-06-28 2004-11-25 Fuji Photo Film Co., Ltd., Minami-Ashigara Benzimidazolderivate und sie enthaltende medikamente
AU776803B2 (en) 1999-06-30 2004-09-23 Fuji Photo Film Co., Ltd. Benzimidazole compounds and medicaments comprising the same
WO2001004110A1 (fr) * 1999-07-07 2001-01-18 Fuji Photo Film Co., Ltd. Composes de benzimidazole
JP4881559B2 (ja) 2002-06-27 2012-02-22 ノボ・ノルデイスク・エー／エス 治療薬としてのアリールカルボニル誘導体
EP2444397A1 (de) 2004-01-06 2012-04-25 Novo Nordisk A/S Heteroarylharnstoffe und ihre Verwendung als Glucokinase-Aktivierer
US8916550B2 (en) 2005-05-09 2014-12-23 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
WO2006122156A2 (en) * 2005-05-09 2006-11-16 Hydra Biosciences, Inc. Compounds for modulating trpv3 function
EP1904438B1 (de) 2005-07-08 2012-02-29 Novo Nordisk A/S Dicycloalkylcarbamoyl-harnstoffe als glucokinase-aktivatoren
AU2006268708A1 (en) 2005-07-08 2007-01-18 Transtech Pharma Inc. Dicycloalkyl urea glucokinase activators
ES2422383T3 (es) 2005-07-14 2013-09-11 Novo Nordisk As Activadores de urea glucoquinasa
WO2008084043A1 (en) 2007-01-09 2008-07-17 Novo Nordisk A/S Urea glucokinase activators
JP5226008B2 (ja) 2007-01-11 2013-07-03 ノボ・ノルデイスク・エー／エス ウレアグルコキナーゼアクチベーター
CN112040945A (zh) 2018-06-12 2020-12-04 Vtv治疗有限责任公司 葡萄糖激酶激活剂与胰岛素或胰岛素类似物组合的治疗用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116433B1 (de) * 1968-04-01 1976-05-24 Fujisawa Pharmaceutical Co
JPS6242989A (ja) * 1986-08-04 1987-02-24 Sumitomo Pharmaceut Co Ltd 溶接電極の自動整形および交換装置
JPH04139172A (ja) * 1990-10-01 1992-05-13 Sankyo Co Ltd α―スルフィニル置換アセトアミド誘導体
US5358946A (en) * 1992-05-29 1994-10-25 The Du Pont Merck Pharmaceutical Company Heterocycle-substituted amides, carbamates and ureas as agents for the treatment of atherosclerosis
JP4191269B2 (ja) * 1996-05-17 2008-12-03 興和株式会社 新規なアニリド化合物及びこれを含有する医薬

Also Published As

Publication number Publication date
AU755654C (en) 2007-03-29
HUP0000729A3 (en) 2001-06-28
DE69834052T2 (de) 2006-11-02
AU1053899A (en) 1999-06-07
ES2262248T3 (es) 2006-11-16
CA2303781A1 (en) 1999-05-27
EP0979823A4 (de) 2002-10-30
JP4402176B2 (ja) 2010-01-20
WO1999025712A1 (fr) 1999-05-27
HUP0000729A2 (hu) 2001-04-28
EP0979823A1 (de) 2000-02-16
TW580498B (en) 2004-03-21
EP0979823B1 (de) 2006-03-29
ATE321759T1 (de) 2006-04-15
AU755654B2 (en) 2002-12-19

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Legal Events

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