ATE321759T1 - Neue amidverbindungen und medikamente die diese enthalten - Google Patents
Neue amidverbindungen und medikamente die diese enthaltenInfo
- Publication number
- ATE321759T1 ATE321759T1 AT98953063T AT98953063T ATE321759T1 AT E321759 T1 ATE321759 T1 AT E321759T1 AT 98953063 T AT98953063 T AT 98953063T AT 98953063 T AT98953063 T AT 98953063T AT E321759 T1 ATE321759 T1 AT E321759T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- atom
- lower alkyl
- alkyl group
- optionally substituted
- Prior art date
Links
- -1 AMIDE COMPOUNDS Chemical class 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 125000004434 sulfur atom Chemical group 0.000 abstract 3
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 2
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 150000003457 sulfones Chemical class 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33087797 | 1997-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321759T1 true ATE321759T1 (de) | 2006-04-15 |
Family
ID=18237521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98953063T ATE321759T1 (de) | 1997-11-14 | 1998-11-16 | Neue amidverbindungen und medikamente die diese enthalten |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0979823B1 (de) |
| JP (1) | JP4402176B2 (de) |
| AT (1) | ATE321759T1 (de) |
| AU (1) | AU755654C (de) |
| CA (1) | CA2303781A1 (de) |
| DE (1) | DE69834052T2 (de) |
| ES (1) | ES2262248T3 (de) |
| HU (1) | HUP0000729A3 (de) |
| TW (1) | TW580498B (de) |
| WO (1) | WO1999025712A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0987254B1 (de) * | 1997-05-26 | 2004-12-22 | Kowa Co., Ltd. | Neue zyklische diaminverbindungen und heilmittel das diese enthält |
| US6969711B2 (en) | 1997-05-26 | 2005-11-29 | Kowa Company, Ltd. | Cyclic diamine compounds and medicine containing the same |
| US6815455B1 (en) | 1999-06-28 | 2004-11-09 | Fuji Photo Film Co., Ltd. | Benzimidazole compounds and drugs containing the same |
| CA2377230C (en) | 1999-06-30 | 2009-06-02 | Kozo Aoki | Benzimidazole compounds and medicaments comprising the same |
| DE60009301T2 (de) * | 1999-07-07 | 2005-02-24 | Fuji Photo Film Co., Ltd., Minami-Ashigara | Benzimidazolverbindungen |
| AU2003243921B2 (en) | 2002-06-27 | 2009-05-07 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
| WO2005066145A1 (en) | 2004-01-06 | 2005-07-21 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| US8916550B2 (en) | 2005-05-09 | 2014-12-23 | Hydra Biosciences, Inc. | Compounds for modulating TRPV3 function |
| EP2392328A1 (de) * | 2005-05-09 | 2011-12-07 | Hydra Biosciences, Inc. | Verbindungen zur Modulierung der TRPV3-Funktion |
| ES2382815T3 (es) | 2005-07-08 | 2012-06-13 | Novo Nordisk A/S | Dicicloalquilcarbamoil ureas como activadores de glucoquinasa |
| CA2614518A1 (en) | 2005-07-08 | 2007-01-18 | Novo-Nordisk A/S | Dicycloalkyl urea glucokinase activators |
| US7884210B2 (en) | 2005-07-14 | 2011-02-08 | Novo Nordisk A/S | Ureido-thiazole glucokinase activators |
| US8138185B2 (en) | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
| US8318778B2 (en) | 2007-01-11 | 2012-11-27 | Novo Nordisk A/S | Urea glucokinase activators |
| KR20210020866A (ko) | 2018-06-12 | 2021-02-24 | 브이티브이 테라퓨틱스 엘엘씨 | 인슐린 또는 인슐린 유사체와 조합된 글루코키나제 활성제의 치료적 용도 |
| WO2021167840A1 (en) | 2020-02-18 | 2021-08-26 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
| EP4161640A4 (de) | 2020-06-08 | 2024-01-17 | vTv Therapeutics LLC | Salze oder cokristalle von {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido)-thiazol-5-ylsulfanyl}-essigsäure und verwendungen davon |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116433B1 (de) * | 1968-04-01 | 1976-05-24 | Fujisawa Pharmaceutical Co | |
| JPS6242989A (ja) * | 1986-08-04 | 1987-02-24 | Sumitomo Pharmaceut Co Ltd | 溶接電極の自動整形および交換装置 |
| JPH04139172A (ja) * | 1990-10-01 | 1992-05-13 | Sankyo Co Ltd | α―スルフィニル置換アセトアミド誘導体 |
| US5358946A (en) * | 1992-05-29 | 1994-10-25 | The Du Pont Merck Pharmaceutical Company | Heterocycle-substituted amides, carbamates and ureas as agents for the treatment of atherosclerosis |
| JP4191269B2 (ja) * | 1996-05-17 | 2008-12-03 | 興和株式会社 | 新規なアニリド化合物及びこれを含有する医薬 |
-
1998
- 1998-11-16 JP JP52814599A patent/JP4402176B2/ja not_active Expired - Fee Related
- 1998-11-16 TW TW087118912A patent/TW580498B/zh not_active IP Right Cessation
- 1998-11-16 AU AU10538/99A patent/AU755654C/en not_active Ceased
- 1998-11-16 ES ES98953063T patent/ES2262248T3/es not_active Expired - Lifetime
- 1998-11-16 HU HU0000729A patent/HUP0000729A3/hu unknown
- 1998-11-16 CA CA002303781A patent/CA2303781A1/en not_active Abandoned
- 1998-11-16 DE DE69834052T patent/DE69834052T2/de not_active Expired - Lifetime
- 1998-11-16 EP EP98953063A patent/EP0979823B1/de not_active Expired - Lifetime
- 1998-11-16 AT AT98953063T patent/ATE321759T1/de not_active IP Right Cessation
- 1998-11-16 WO PCT/JP1998/005149 patent/WO1999025712A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999025712A1 (en) | 1999-05-27 |
| HUP0000729A3 (en) | 2001-06-28 |
| AU755654C (en) | 2007-03-29 |
| CA2303781A1 (en) | 1999-05-27 |
| AU755654B2 (en) | 2002-12-19 |
| ES2262248T3 (es) | 2006-11-16 |
| EP0979823A1 (de) | 2000-02-16 |
| JP4402176B2 (ja) | 2010-01-20 |
| TW580498B (en) | 2004-03-21 |
| DE69834052D1 (de) | 2006-05-18 |
| AU1053899A (en) | 1999-06-07 |
| EP0979823B1 (de) | 2006-03-29 |
| EP0979823A4 (de) | 2002-10-30 |
| DE69834052T2 (de) | 2006-11-02 |
| HUP0000729A2 (hu) | 2001-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE321759T1 (de) | Neue amidverbindungen und medikamente die diese enthalten | |
| DE69828276D1 (de) | Neue zyklische diaminverbindungen und heilmittel das diese enthält | |
| MXPA04003398A (es) | Activador para el receptor o activado con el proliferador de peroxisoma. | |
| ATE251608T1 (de) | Neue trizyklische verbindungen und arzneimittelzusammensetzungen die diese enthalten | |
| IL113313A (en) | Heterocyclic compounds and pharmaceutical compositions containing the same | |
| NZ240676A (en) | Heterocyclic compounds substituted by a (piperidin-4-yl)-1-oxoalkyl group and pharmaceutical compositions thereof | |
| DE69512117D1 (de) | Flüssigkristallverbindungen und diese enthaltende Flüssigkristallzusammensetzung | |
| ATE190052T1 (de) | Thiazolidindione-derivate, ihre herstellung und verwendung | |
| ES2128440T3 (es) | Derivado de 4-alcoxi-2,6-di-t-butilfenol. | |
| DE69132651D1 (de) | Schwefel enthaltende heterocyclische Verbindungen | |
| DE69937045D1 (de) | Cyclische amidderivate | |
| ATE97410T1 (de) | 6-amino-6-desoxyfumagillole, ihre herstellung und ihre verwendung. | |
| DE69525763D1 (de) | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENE, DIE LDL OXIDATION HEMMEN | |
| EP1020451A4 (de) | Neue anilidverbindungen und medikamente, die diese enthalten | |
| KR970702848A (ko) | 아릴피페리딘 및 아릴피페라진 유도체 및 이를 함유하는 약제(Arylpiperidine and arylpiperazine derivatives and drugs containing the same) | |
| DE69319859D1 (de) | Neue tetracyclische verbindungen | |
| ATE157365T1 (de) | Thiophenverbindungen und ihre pharmazeutischen verwendungen | |
| TH53444A (th) | สารประกอบอะไมด์ที่พบใหม่และยาที่มีสารประกอบดังกล่าว |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |