DE69819340D1 - Optisch reine camptothecinanaloge, optisch reines synthese-zwischenprodukt und verfahren zu ihrer herstellung - Google Patents
Optisch reine camptothecinanaloge, optisch reines synthese-zwischenprodukt und verfahren zu ihrer herstellungInfo
- Publication number
- DE69819340D1 DE69819340D1 DE69819340T DE69819340T DE69819340D1 DE 69819340 D1 DE69819340 D1 DE 69819340D1 DE 69819340 T DE69819340 T DE 69819340T DE 69819340 T DE69819340 T DE 69819340T DE 69819340 D1 DE69819340 D1 DE 69819340D1
- Authority
- DE
- Germany
- Prior art keywords
- optically pure
- production
- intermediate product
- synthesis intermediate
- camptothecin analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9710785A FR2768431B1 (fr) | 1997-08-29 | 1997-08-29 | Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation |
FR9710785 | 1997-08-29 | ||
PCT/FR1998/001768 WO1999011646A1 (fr) | 1997-08-29 | 1998-08-07 | Analogues optiquement purs de la camptothecine, intermediaire de synthese optiquement pur et son procede de preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69819340D1 true DE69819340D1 (de) | 2003-12-04 |
DE69819340T2 DE69819340T2 (de) | 2004-08-19 |
Family
ID=9510590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69819340T Expired - Lifetime DE69819340T2 (de) | 1997-08-29 | 1998-08-07 | Optisch reine camptothecinanaloge, optisch reines synthese-zwischenprodukt und verfahren zu ihrer herstellung |
Country Status (26)
Country | Link |
---|---|
EP (2) | EP1007527B1 (de) |
JP (1) | JP2001514261A (de) |
KR (1) | KR100570254B1 (de) |
CN (3) | CN1195758C (de) |
AR (1) | AR016856A1 (de) |
AT (1) | ATE253069T1 (de) |
AU (1) | AU760863B2 (de) |
BR (1) | BR9811405A (de) |
CA (1) | CA2301739C (de) |
CZ (1) | CZ297896B6 (de) |
DE (1) | DE69819340T2 (de) |
DK (1) | DK1007527T3 (de) |
ES (1) | ES2209196T3 (de) |
FR (1) | FR2768431B1 (de) |
HK (2) | HK1031732A1 (de) |
HR (1) | HRP20000110A2 (de) |
HU (1) | HUP0003429A3 (de) |
IL (2) | IL134437A0 (de) |
NO (1) | NO324882B1 (de) |
NZ (1) | NZ502862A (de) |
PL (1) | PL195289B1 (de) |
PT (1) | PT1007527E (de) |
RU (1) | RU2233283C2 (de) |
TW (1) | TW419479B (de) |
WO (1) | WO1999011646A1 (de) |
ZA (1) | ZA987445B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790261B1 (fr) | 1999-02-26 | 2004-09-10 | Sod Conseils Rech Applic | Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation |
US6207832B1 (en) | 1999-04-09 | 2001-03-27 | University Of Pittsburgh | Camptothecin analogs and methods of preparation thereof |
US6372906B1 (en) | 2001-04-12 | 2002-04-16 | University Of Pittsburgh | Synthesis of silyl camptothecins and silyl homocamptothecins |
US6723853B2 (en) | 2001-08-27 | 2004-04-20 | University Of Pittsburgh | Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins |
CN100408582C (zh) * | 2004-02-12 | 2008-08-06 | 中国人民解放军第二军医大学 | 高喜树碱类化合物及其制备方法和用途 |
CA2580747A1 (en) * | 2004-09-21 | 2006-03-30 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R .A.S.) | Novel processes for the production of useful intermediates |
CN100465175C (zh) * | 2005-11-29 | 2009-03-04 | 中国人民解放军第二军医大学 | 7-位取代高喜树碱类化合物及作为药物的用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5459269A (en) * | 1992-06-18 | 1995-10-17 | North Carolina State University | 14-halo-camptothecins |
PT835258E (pt) * | 1995-06-21 | 2003-02-28 | Sod Conseils Rech Applic | Novos analogos de camptotecina, processos para a sua preparacao, sua utilizacao como farmacos e composicoes farmaceuticas que os contem |
-
1997
- 1997-08-29 FR FR9710785A patent/FR2768431B1/fr not_active Expired - Fee Related
-
1998
- 1998-08-07 EP EP98941567A patent/EP1007527B1/de not_active Expired - Lifetime
- 1998-08-07 CN CNB031021662A patent/CN1195758C/zh not_active Expired - Fee Related
- 1998-08-07 AT AT98941567T patent/ATE253069T1/de active
- 1998-08-07 DK DK98941567T patent/DK1007527T3/da active
- 1998-08-07 CZ CZ20000711A patent/CZ297896B6/cs not_active IP Right Cessation
- 1998-08-07 KR KR1020007002034A patent/KR100570254B1/ko not_active IP Right Cessation
- 1998-08-07 ES ES98941567T patent/ES2209196T3/es not_active Expired - Lifetime
- 1998-08-07 NZ NZ502862A patent/NZ502862A/xx unknown
- 1998-08-07 WO PCT/FR1998/001768 patent/WO1999011646A1/fr active IP Right Grant
- 1998-08-07 BR BR9811405-0A patent/BR9811405A/pt not_active Application Discontinuation
- 1998-08-07 CN CN98808720A patent/CN1104434C/zh not_active Expired - Lifetime
- 1998-08-07 CA CA002301739A patent/CA2301739C/fr not_active Expired - Fee Related
- 1998-08-07 RU RU2000107822/04A patent/RU2233283C2/ru not_active IP Right Cessation
- 1998-08-07 PT PT98941567T patent/PT1007527E/pt unknown
- 1998-08-07 HU HU0003429A patent/HUP0003429A3/hu unknown
- 1998-08-07 PL PL98338835A patent/PL195289B1/pl not_active IP Right Cessation
- 1998-08-07 IL IL13443798A patent/IL134437A0/xx active IP Right Grant
- 1998-08-07 DE DE69819340T patent/DE69819340T2/de not_active Expired - Lifetime
- 1998-08-07 JP JP2000508685A patent/JP2001514261A/ja active Pending
- 1998-08-07 EP EP03077049A patent/EP1378512A1/de not_active Withdrawn
- 1998-08-07 AU AU89896/98A patent/AU760863B2/en not_active Ceased
- 1998-08-18 ZA ZA987445A patent/ZA987445B/xx unknown
- 1998-08-19 TW TW087113646A patent/TW419479B/zh not_active IP Right Cessation
- 1998-08-21 AR ARP980104157A patent/AR016856A1/es active IP Right Grant
-
2000
- 2000-02-08 IL IL134437A patent/IL134437A/en not_active IP Right Cessation
- 2000-02-28 NO NO20000995A patent/NO324882B1/no not_active IP Right Cessation
- 2000-02-29 HR HR20000110A patent/HRP20000110A2/hr not_active Application Discontinuation
-
2001
- 2001-04-03 HK HK01102373A patent/HK1031732A1/xx not_active IP Right Cessation
-
2003
- 2003-02-08 CN CN03102165A patent/CN1440972A/zh active Pending
-
2004
- 2004-02-25 HK HK04101371A patent/HK1058665A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR |