DE69615668T2 - O-carbamoyl-(d)-phenylalanilolverbindungen und verfahren zu ihrer herstellung. - Google Patents

O-carbamoyl-(d)-phenylalanilolverbindungen und verfahren zu ihrer herstellung.

Info

Publication number
DE69615668T2
DE69615668T2 DE69615668T DE69615668T DE69615668T2 DE 69615668 T2 DE69615668 T2 DE 69615668T2 DE 69615668 T DE69615668 T DE 69615668T DE 69615668 T DE69615668 T DE 69615668T DE 69615668 T2 DE69615668 T2 DE 69615668T2
Authority
DE
Germany
Prior art keywords
phenylalanilol
carbamoyl
compounds
production
phenylalanilol compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69615668T
Other languages
English (en)
Other versions
DE69615668D1 (de
Inventor
Moon Choi
Il Han
Kil Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Inc
Original Assignee
SK Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SK Corp filed Critical SK Corp
Application granted granted Critical
Publication of DE69615668D1 publication Critical patent/DE69615668D1/de
Publication of DE69615668T2 publication Critical patent/DE69615668T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
DE69615668T 1995-02-11 1996-02-08 O-carbamoyl-(d)-phenylalanilolverbindungen und verfahren zu ihrer herstellung. Expired - Lifetime DE69615668T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019950002543A KR0173862B1 (ko) 1995-02-11 1995-02-11 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
PCT/KR1996/000018 WO1996024577A1 (en) 1995-02-11 1996-02-08 O-carbamoyl-(d)-phenylalanilol compounds and process for preparing the same

Publications (2)

Publication Number Publication Date
DE69615668D1 DE69615668D1 (de) 2001-11-08
DE69615668T2 true DE69615668T2 (de) 2002-07-11

Family

ID=19408007

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69615668T Expired - Lifetime DE69615668T2 (de) 1995-02-11 1996-02-08 O-carbamoyl-(d)-phenylalanilolverbindungen und verfahren zu ihrer herstellung.

Country Status (11)

Country Link
US (1) US5705640C1 (de)
EP (1) EP0815074B1 (de)
JP (1) JP3828574B2 (de)
KR (1) KR0173862B1 (de)
CN (1) CN1070846C (de)
CA (1) CA2212326C (de)
DE (1) DE69615668T2 (de)
DK (1) DK0815074T3 (de)
ES (1) ES2165485T3 (de)
PT (1) PT815074E (de)
WO (1) WO1996024577A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0173863B1 (ko) * 1995-04-10 1999-04-01 조규향 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
ES2170878T3 (es) * 1996-10-10 2002-08-16 Sk Corp Compuestos de o-carbamoil-fenilalaninol y sus sales farmaceuticamente utiles.
JP2008518921A (ja) * 2004-10-28 2008-06-05 エスケー ホルディングス カンパニー リミテッド うつ病のための補助療法
PL1890684T3 (pl) * 2005-06-08 2014-05-30 Sk Biopharmaceuticals Co Ltd Leczenie zaburzeń snu i czuwania
JP5298334B2 (ja) * 2005-06-22 2013-09-25 エスケー ホルディングス カンパニー リミテッド 性機能障害を治療する方法
JP2010506845A (ja) * 2006-10-13 2010-03-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ フェニルアルキルアミノカルバメート組成物
US8642772B2 (en) * 2008-10-14 2014-02-04 Sk Biopharmaceuticals Co., Ltd. Piperidine compounds, pharmaceutical composition comprising the same and its use
EP2445490B1 (de) * 2009-06-22 2023-02-08 SK Biopharmaceuticals Co., Ltd. Verfahren zur behandlung oder verhinderung von ermüdung
US8232315B2 (en) * 2009-06-26 2012-07-31 Sk Biopharmaceuticals Co., Ltd. Methods for treating drug addiction and improving addiction-related behavior
AU2010316106B2 (en) 2009-11-06 2015-10-22 Sk Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
MX350745B (es) 2009-11-06 2017-09-14 Sk Biopharmaceuticals Co Ltd * El uso de un compuesto de carbamoilo para el tratamiento del sindrome de fibromialgia.
US8623913B2 (en) 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
PT2968208T (pt) 2013-03-13 2022-10-28 Aerial Biopharma Llc Tratamento da cataplexia
PL3021838T3 (pl) 2013-07-18 2021-03-08 Jazz Pharmaceuticals Ireland Limited Leczenie otyłości
US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
TWI698415B (zh) * 2014-02-28 2020-07-11 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
WO2018048871A1 (en) 2016-09-06 2018-03-15 Jazz Pharmaceuticals International Iii Limited Solvate form of (r)-2-amino-3-phenylpropyl carbamate
WO2018067971A1 (en) 2016-10-06 2018-04-12 Jazz Pharmaceuticals International Iii Limited Carbamoyl phenylalaninol compounds and uses therof
MX2019014409A (es) 2017-06-02 2022-03-17 Jazz Pharmaceuticals Ireland Ltd Métodos y composiciones para tratar somnolencia excesiva.
EP3661911A4 (de) 2017-07-31 2021-04-14 Jazz Pharmaceuticals Ireland Limited Carbamoyl-phenylalaninol-analoga und verwendungen davon
CN110655500B (zh) * 2018-06-28 2020-12-08 浙江京新药业股份有限公司 氨基甲酸酯衍生物及其制备方法和用途
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물
WO2023091921A1 (en) * 2021-11-16 2023-05-25 Axsome Malta Ltd. Methods and compositions for treating cognitive impairment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470277A1 (de) * 1963-04-18 1969-05-29 Siegfried Ag Verfahren zur Herstellung von spasmolytische und tremolytische Eigenschaften aufweisenden Carbaminaten
FR8411M (de) * 1968-12-31 1971-03-31
AT387572B (de) * 1983-05-20 1989-02-10 Ferrosan Ab Verfahren zur herstellung von neuen 4-(4,4-bis-(p-fluorphenyl)-butyl)-1-carbophenox -piperazinen und von 1-piperazincarboxamiden
KR100197892B1 (ko) * 1994-09-09 1999-06-15 남창우 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법

Also Published As

Publication number Publication date
KR960031427A (ko) 1996-09-17
ES2165485T3 (es) 2002-03-16
JPH11501617A (ja) 1999-02-09
KR0173862B1 (ko) 1999-04-01
PT815074E (pt) 2002-03-28
CN1173863A (zh) 1998-02-18
JP3828574B2 (ja) 2006-10-04
EP0815074A1 (de) 1998-01-07
CN1070846C (zh) 2001-09-12
WO1996024577A1 (en) 1996-08-15
US5705640C1 (en) 2001-03-20
CA2212326C (en) 2008-12-23
DE69615668D1 (de) 2001-11-08
CA2212326A1 (en) 1996-08-15
EP0815074B1 (de) 2001-10-04
US5705640A (en) 1998-01-06
DK0815074T3 (da) 2002-01-28

Similar Documents

Publication Publication Date Title
DE69615668T2 (de) O-carbamoyl-(d)-phenylalanilolverbindungen und verfahren zu ihrer herstellung.
DE59602652D1 (de) Zahnbürste und verfahren zu ihrer herstellung
DE59606535D1 (de) Furnacerusse und Verfahren zu ihrer Herstellung
ATE206131T1 (de) Phosphonomonoesternnukleinsäuren, verfahren zu ihrer herstellung und ihre verwendung
DE69611599D1 (de) Halbaromatische polyamidzusamensetzung und verfahren zu ihrer herstellung
DE69733416D1 (de) Erythromycine und verfahren zu ihrer herstellung
DE69620405T2 (de) Verbesserte polyarylenetherzusammensetzungen und verfahren zu ihrer herstellung
DE69636166D1 (de) Klebstoffzusammensetzung und verfahren zu ihrer herstellung
DE59603578D1 (de) Flachdichtung und verfahren zu ihrer herstellung
DE69433296D1 (de) Eisen-lactoferrin kombination und verfahren zu ihrer herstellung
DE69625176T2 (de) Camptothecin-derivate und verfahren zu ihrer herstellung
DE69622368D1 (de) Schwefelverbindungen und verfahren zu ihrer herstellung
DE59600453D1 (de) Zinnbadbodenstein, und Verfahren zu seiner Herstellung
DE69510774D1 (de) Katschukzusammensetzung und verfahren zu ihrer herstellung
DE69617035D1 (de) Waschmittelzusammensetzungen und verfahren zu ihrer herstellung
DE69626009T2 (de) Pyrrolidinylhydroxamsäuren und verfahren zu ihrer herstellung
DE69801795T2 (de) Indolyl-pyrrolylidenmethylpyrrol-derivate und verfahren zu ihrer herstellung
DE69536010D1 (de) Nassreibungsmaterial und verfahren zu ihrer herstellung
DE69614524D1 (de) Etherverbindungen und verfahren zu ihrer herstellung
DE69523571T2 (de) Pyridylimidazol-derivate und verfahren zu ihrer herstellung
DE69628580D1 (de) Pestizide verbindungen, verfahren zu ihrer herstellung und zusammensetzungen
DE69735099D1 (de) Antibiotika rk-1061 und verfahren zu ihrer herstellung
DE69527445T2 (de) Aminooligosaccharid-derivate und verfahren zu ihrer herstellung
DE69609986T2 (de) Bitumenzusammensetzungen und verfahren zu ihrer herstellung
DE69603746T2 (de) Bitumenzusammensetzungen und verfahren zu ihrer herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SK HOLDINGS CO., LTD., SEOUL, KR

R082 Change of representative

Ref document number: 815074

Country of ref document: EP

Representative=s name: BEETZ & PARTNER PATENT- UND RECHTSANWAELTE, 80538