HK1031732A1 - Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same - Google Patents

Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same

Info

Publication number
HK1031732A1
HK1031732A1 HK01102373A HK01102373A HK1031732A1 HK 1031732 A1 HK1031732 A1 HK 1031732A1 HK 01102373 A HK01102373 A HK 01102373A HK 01102373 A HK01102373 A HK 01102373A HK 1031732 A1 HK1031732 A1 HK 1031732A1
Authority
HK
Hong Kong
Prior art keywords
optically pure
preparing same
synthesis intermediate
camptothecin analogues
analogues
Prior art date
Application number
HK01102373A
Other languages
English (en)
Inventor
Jean-Bernard Cazaux
Olivier Lavergne
Breton Christine Le
Eric Manginot
Dennis Bigg
Original Assignee
S C R A S Soc De Conseils De R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S C R A S Soc De Conseils De R filed Critical S C R A S Soc De Conseils De R
Publication of HK1031732A1 publication Critical patent/HK1031732A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
HK01102373A 1997-08-29 2001-04-03 Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same HK1031732A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9710785A FR2768431B1 (fr) 1997-08-29 1997-08-29 Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
PCT/FR1998/001768 WO1999011646A1 (fr) 1997-08-29 1998-08-07 Analogues optiquement purs de la camptothecine, intermediaire de synthese optiquement pur et son procede de preparation

Publications (1)

Publication Number Publication Date
HK1031732A1 true HK1031732A1 (en) 2001-06-22

Family

ID=9510590

Family Applications (2)

Application Number Title Priority Date Filing Date
HK01102373A HK1031732A1 (en) 1997-08-29 2001-04-03 Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same
HK04101371A HK1058665A1 (en) 1997-08-29 2004-02-25 Optically pure camptothecin analogues.

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK04101371A HK1058665A1 (en) 1997-08-29 2004-02-25 Optically pure camptothecin analogues.

Country Status (26)

Country Link
EP (2) EP1378512A1 (xx)
JP (1) JP2001514261A (xx)
KR (1) KR100570254B1 (xx)
CN (3) CN1195758C (xx)
AR (1) AR016856A1 (xx)
AT (1) ATE253069T1 (xx)
AU (1) AU760863B2 (xx)
BR (1) BR9811405A (xx)
CA (1) CA2301739C (xx)
CZ (1) CZ297896B6 (xx)
DE (1) DE69819340T2 (xx)
DK (1) DK1007527T3 (xx)
ES (1) ES2209196T3 (xx)
FR (1) FR2768431B1 (xx)
HK (2) HK1031732A1 (xx)
HR (1) HRP20000110A2 (xx)
HU (1) HUP0003429A3 (xx)
IL (2) IL134437A0 (xx)
NO (1) NO324882B1 (xx)
NZ (1) NZ502862A (xx)
PL (1) PL195289B1 (xx)
PT (1) PT1007527E (xx)
RU (1) RU2233283C2 (xx)
TW (1) TW419479B (xx)
WO (1) WO1999011646A1 (xx)
ZA (1) ZA987445B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (fr) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
EP1794127A1 (en) * 2004-09-21 2007-06-13 Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) Novel processes for the production of useful intermediates
CN100465175C (zh) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-位取代高喜树碱类化合物及作为药物的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459269A (en) * 1992-06-18 1995-10-17 North Carolina State University 14-halo-camptothecins
CN1114608C (zh) * 1995-06-21 2003-07-16 科学研究与运用咨询公司 喜树碱类似物、其制备方法和药物应用及其药物组合物

Also Published As

Publication number Publication date
FR2768431A1 (fr) 1999-03-19
CA2301739A1 (fr) 1999-03-11
KR20010023394A (ko) 2001-03-26
CN1195758C (zh) 2005-04-06
CN1440972A (zh) 2003-09-10
PL195289B1 (pl) 2007-08-31
ATE253069T1 (de) 2003-11-15
RU2233283C2 (ru) 2004-07-27
AR016856A1 (es) 2001-08-01
HUP0003429A1 (hu) 2001-07-30
ZA987445B (en) 1999-02-17
DK1007527T3 (da) 2004-03-08
IL134437A (en) 2006-08-01
HUP0003429A3 (en) 2002-11-28
DE69819340D1 (de) 2003-12-04
IL134437A0 (en) 2001-04-30
DE69819340T2 (de) 2004-08-19
CZ297896B6 (cs) 2007-04-25
WO1999011646A1 (fr) 1999-03-11
AU8989698A (en) 1999-03-22
BR9811405A (pt) 2000-08-29
PT1007527E (pt) 2004-03-31
NO324882B1 (no) 2007-12-27
CN1104434C (zh) 2003-04-02
CZ2000711A3 (cs) 2000-08-16
EP1007527A1 (fr) 2000-06-14
AU760863B2 (en) 2003-05-22
NZ502862A (en) 2002-10-25
EP1378512A1 (fr) 2004-01-07
ES2209196T3 (es) 2004-06-16
JP2001514261A (ja) 2001-09-11
HRP20000110A2 (en) 2001-02-28
CN1268948A (zh) 2000-10-04
HK1058665A1 (en) 2004-05-28
FR2768431B1 (fr) 2000-03-24
PL338835A1 (en) 2000-11-20
CN1440973A (zh) 2003-09-10
NO20000995D0 (no) 2000-02-28
TW419479B (en) 2001-01-21
KR100570254B1 (ko) 2006-04-12
NO20000995L (no) 2000-02-28
CA2301739C (fr) 2009-11-17
EP1007527B1 (fr) 2003-10-29

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110807