DE69802113T2 - Zusammensetzungen zur erhöhung der konzentration und/oder beweglichkeit von samenzellen in menschen - Google Patents

Zusammensetzungen zur erhöhung der konzentration und/oder beweglichkeit von samenzellen in menschen

Info

Publication number
DE69802113T2
DE69802113T2 DE69802113T DE69802113T DE69802113T2 DE 69802113 T2 DE69802113 T2 DE 69802113T2 DE 69802113 T DE69802113 T DE 69802113T DE 69802113 T DE69802113 T DE 69802113T DE 69802113 T2 DE69802113 T2 DE 69802113T2
Authority
DE
Germany
Prior art keywords
mobility
humans
compositions
concentration
increasing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69802113T
Other languages
English (en)
Other versions
DE69802113D1 (de
Inventor
Claudio Cavazza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau HealthScience SpA
Original Assignee
Sigma Tau HealthScience SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/980,821 external-priority patent/US5863940A/en
Application filed by Sigma Tau HealthScience SpA filed Critical Sigma Tau HealthScience SpA
Application granted granted Critical
Publication of DE69802113D1 publication Critical patent/DE69802113D1/de
Publication of DE69802113T2 publication Critical patent/DE69802113T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69802113T 1997-12-01 1998-11-18 Zusammensetzungen zur erhöhung der konzentration und/oder beweglichkeit von samenzellen in menschen Expired - Lifetime DE69802113T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/980,821 US5863940A (en) 1997-12-01 1997-12-01 Medicament and therapeutical method for treating idiopathic asthenozoospermia
US09/122,897 US6090848A (en) 1997-12-01 1998-07-28 Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
PCT/IT1998/000324 WO1999027925A1 (en) 1997-12-01 1998-11-18 Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans

Publications (2)

Publication Number Publication Date
DE69802113D1 DE69802113D1 (de) 2001-11-22
DE69802113T2 true DE69802113T2 (de) 2002-06-06

Family

ID=26820998

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802113T Expired - Lifetime DE69802113T2 (de) 1997-12-01 1998-11-18 Zusammensetzungen zur erhöhung der konzentration und/oder beweglichkeit von samenzellen in menschen

Country Status (23)

Country Link
US (1) US6090848A (de)
EP (1) EP1039894B1 (de)
JP (1) JP2001524520A (de)
KR (1) KR20010032702A (de)
CN (1) CN1184966C (de)
AT (1) ATE206916T1 (de)
AU (1) AU749754B2 (de)
BR (1) BR9814711A (de)
CA (1) CA2314942C (de)
DE (1) DE69802113T2 (de)
DK (1) DK1039894T3 (de)
EE (1) EE200000309A (de)
ES (1) ES2163896T3 (de)
HK (1) HK1033280A1 (de)
HU (1) HU228989B1 (de)
IL (1) IL136299A0 (de)
IS (1) IS5501A (de)
NO (1) NO20002798L (de)
PL (1) PL192438B1 (de)
PT (1) PT1039894E (de)
SK (1) SK7572000A3 (de)
TR (1) TR200001519T2 (de)
WO (1) WO1999027925A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383814C (en) * 1999-09-03 2010-08-17 Sigma-Tau Healthscience S.P.A. Ultrafine l-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same
ITRM20010029A1 (it) * 2001-01-23 2002-07-23 Aldo Fassi Sali metallici di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per
LV12978B (en) * 2001-09-07 2003-05-20 Ivars Kalvins Pharmaceutical composition
WO2003022302A2 (en) * 2001-09-12 2003-03-20 Applied Research Systems Ars Holding N.V. USE OF hCG IN CONTROLLED OVARIAN HYPERSTIMULATION
PL369021A1 (en) * 2001-09-12 2005-04-18 Applied Research Systems Ars Holding N.V. Use of hcg and lh in controlled ovarian hyperstimulation
ITRM20010621A1 (it) * 2001-10-18 2003-04-18 Aldo Fassi Sali metallici non igroscopici e idrosolubili di alcanoil l-carnitine, integratori dietetici che li contengono e kit dietetici, per contrast
ITRM20020194A1 (it) * 2002-04-09 2003-10-09 Sigma Tau Healthscience Spa Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo.
US7776913B2 (en) 2002-12-13 2010-08-17 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Carnitines for treating or preventing disorders caused by andropause
AT503219B1 (de) 2006-02-03 2008-07-15 Annerl Brigitte Kombinationspräparat auf basis von antioxidanzien zur verbesserung der samenqualität
BRPI0717439A2 (pt) * 2006-10-18 2013-11-19 Periness Ltd Composição farmacêutica, e, métodos para tratar subfertilidade masculina, para determinar um estado de fertlidade em um indivíduo do sexo masculino, para a reprodução assistida, para selecionar uma técnica de reprodução assistida e para selecionar células de esperma em uma população de células de esperma para uso em uma técnica de reprodução auxiliada.
DE102007053369A1 (de) 2007-11-09 2009-07-02 Alzchem Trostberg Gmbh Verwendung einer eine Kreatin-Komponente enthaltende Zusammensetzung zur Verbesserung der männlichen Fruchtbarkeit
WO2009068278A2 (en) * 2007-11-30 2009-06-04 Bayer Consumer Care Ag A pharmaceutical composition
US20110015154A1 (en) * 2009-07-20 2011-01-20 Kellermann Gottfried H Supporting acetylcholine function
US20110098265A1 (en) * 2009-10-28 2011-04-28 Neuroscience, Inc. Methods for reducing cravings and impulses associated with addictive and compulsive behaviors
US10076541B2 (en) * 2013-12-05 2018-09-18 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful as a dietary supplement
CN105695398A (zh) * 2016-04-25 2016-06-22 广西大学 含o-乙酰基-l-肉碱盐酸盐的水牛卵母细胞体外成熟液及培养方法
ES2813573T3 (es) * 2016-07-11 2021-03-24 Laboratoire Des Granions Composición que comprende L-carnitina para el tratamiento de la infertilidad masculina
CN107375346A (zh) * 2017-07-25 2017-11-24 昭远制药(上海)有限公司 提高人类精子浓度和运动性的组合物及其制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1235153B (it) * 1988-11-15 1992-06-22 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento
IT1224795B (it) * 1988-12-01 1990-10-24 Sigma Tau Ind Farmaceuti Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1240760B (it) * 1990-02-12 1993-12-17 Sigma Tau Ind Farmaceuti Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma.
IT1240799B (it) * 1990-03-15 1993-12-17 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti 3-metiltiopropionil l-carnitina ad attivita' sul sistema cardiovascolare.
IT1244636B (it) * 1991-01-04 1994-08-08 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
IT1248323B (it) * 1991-05-16 1995-01-05 Sigma Tau Ind Farmaceuti Ammidi con amminoacidi naturali di alcanoil l-carnitine quali inibitori della degenerazione neuronale e attivatori dei processi di apprendimento e memorizzazione e per il trattamento del coma e composizioni farmaceutiche comprendenti tali composti
IT1245699B (it) * 1991-05-29 1994-10-14 Sigma Tau Ind Farmaceuti Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi
IT1249462B (it) * 1991-10-21 1995-02-23 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e acil l-carnitine nel trattamento delle oligoastenospermie idiopatiche.
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
IT1263013B (it) * 1992-10-20 1996-07-23 Avantgarde Spa Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee.
IT1261688B (it) * 1993-05-28 1996-05-29 Avantgarde Spa Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
IT1261696B (it) * 1993-06-02 1996-05-29 Avantgarde Spa Uso di esteri sull'ossidrile della l-carnitina con acidi aromatici perprodurre composizioni farmaceutiche per il trattamento di affezioni cutanee.
IT1261984B (it) * 1993-06-22 1996-06-11 Avantgarde Spa Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
IT1272290B (it) * 1994-06-20 1997-06-16 Avantgarde Spa Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee
IT1274156B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
IT1274157B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
US5889055A (en) * 1997-04-04 1999-03-30 Howard; James R. L-carnitine and acetyl-L-carnitine combined for prevention and treatment of syndromes related to diseases of energy metabolism
IT1295408B1 (it) * 1997-10-03 1999-05-12 Sigma Tau Ind Farmaceuti Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo

Also Published As

Publication number Publication date
PL342115A1 (en) 2001-05-21
CN1284871A (zh) 2001-02-21
HK1033280A1 (en) 2001-08-24
IL136299A0 (en) 2001-05-20
AU749754B2 (en) 2002-07-04
JP2001524520A (ja) 2001-12-04
CA2314942A1 (en) 1999-06-10
CA2314942C (en) 2009-05-05
TR200001519T2 (tr) 2000-11-21
CN1184966C (zh) 2005-01-19
SK7572000A3 (en) 2000-11-07
EP1039894B1 (de) 2001-10-17
NO20002798D0 (no) 2000-05-31
US6090848A (en) 2000-07-18
WO1999027925A1 (en) 1999-06-10
NO20002798L (no) 2000-06-27
DE69802113D1 (de) 2001-11-22
HUP0004562A3 (en) 2003-05-28
AU1259199A (en) 1999-06-16
DK1039894T3 (da) 2002-02-11
ES2163896T3 (es) 2002-02-01
IS5501A (is) 2000-05-19
BR9814711A (pt) 2000-10-03
KR20010032702A (ko) 2001-04-25
EE200000309A (et) 2001-08-15
PT1039894E (pt) 2002-04-29
HUP0004562A2 (hu) 2001-05-28
PL192438B1 (pl) 2006-10-31
EP1039894A1 (de) 2000-10-04
HU228989B1 (en) 2013-07-29
ATE206916T1 (de) 2001-11-15

Similar Documents

Publication Publication Date Title
DE69802113T2 (de) Zusammensetzungen zur erhöhung der konzentration und/oder beweglichkeit von samenzellen in menschen
ES2173948T3 (es) Mezclas de 2',3'-didesoxi-inosina e hidrocarbamida para la inhibicion de la propagacion retroviral.
PT814789E (pt) Composicoes farmaceuticas compreendendo inibidores de monoamina-oxidase b
DE60116302D1 (de) Behandlung von seborrhoischer dermatitis
ATE152628T1 (de) Verwendung von parathormone, seinen biologisch aktiven fragmenten oder von verwandten peptiden zur behandlung von schwangerschaft
IT1276162B1 (it) Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche
AU567018B2 (en) Prazosin-pirbuterol combination for bronchoduation
MX9705916A (es) Terapia de combinacion para infeccion por vih usando el inhibidor de proteasa de vih indinavir y el inhibidor de transcriptasa inversa 3tc, opcionalmente junto con azt, ddi, o ddc.
CO4910113A1 (es) Composiciones farmaceuticas estabilizadas, a base de quinu- pristina y de dalfopristina y su preparacion
DE69424679T2 (de) Zusammensetzung zur behandlung oder vorbeugung von herpes
AR008764A1 (es) Sales hidratadas de n,n'-diacetilcistina, proceso para su preparacion, y composiciones terapeuticas que comprenden a dichas sales como ingredienteactivo.
ES2162022T3 (es) Derivados de tiol con actividad inhibidora de la metalopeptidasa.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition