IT1224795B - Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento - Google Patents

Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento

Info

Publication number
IT1224795B
IT1224795B IT8848614A IT4861488A IT1224795B IT 1224795 B IT1224795 B IT 1224795B IT 8848614 A IT8848614 A IT 8848614A IT 4861488 A IT4861488 A IT 4861488A IT 1224795 B IT1224795 B IT 1224795B
Authority
IT
Italy
Prior art keywords
treatment
carnitine
glaucoma
acetyl
pharmaceutical compositions
Prior art date
Application number
IT8848614A
Other languages
English (en)
Other versions
IT8848614A0 (it
Inventor
Cavazza Claudio
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IT8848614A0 publication Critical patent/IT8848614A0/it
Priority to IT8848614A priority Critical patent/IT1224795B/it
Priority to AU46584/89A priority patent/AU628116B2/en
Priority to AT90900320T priority patent/ATE88090T1/de
Priority to ES199090900320T priority patent/ES2040106T3/es
Priority to DE1989606028 priority patent/DE68906028T2/de
Priority to EP90900320A priority patent/EP0446268B1/en
Priority to PCT/IT1989/000076 priority patent/WO1990006111A1/en
Priority to JP2502051A priority patent/JP2763400B2/ja
Priority to KR1019900701559A priority patent/KR950004885B1/ko
Priority to US07/442,702 priority patent/US5145871A/en
Priority to CA002004239A priority patent/CA2004239C/en
Priority to IE384089A priority patent/IE62568B1/en
Priority to ZA899176A priority patent/ZA899176B/xx
Priority to GR890100797A priority patent/GR1000465B/el
Application granted granted Critical
Publication of IT1224795B publication Critical patent/IT1224795B/it
Priority to US07/689,527 priority patent/US5432199A/en
Priority to DK199100950A priority patent/DK175891B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IT8848614A 1988-12-01 1988-12-01 Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento IT1224795B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT8848614A IT1224795B (it) 1988-12-01 1988-12-01 Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento
KR1019900701559A KR950004885B1 (ko) 1988-12-01 1989-11-27 아세틸 d-카르니틴을 함유하는 녹내장 치료제
AT90900320T ATE88090T1 (de) 1988-12-01 1989-11-27 Verwendung von acetyl-d-carnitin zur therapeutischen behandlung von glaukom.
ES199090900320T ES2040106T3 (es) 1988-12-01 1989-11-27 Utilizacion de la acetil d-carnitina en el tratamiento terapeutico del glaucoma.
DE1989606028 DE68906028T2 (de) 1988-12-01 1989-11-27 Verwendung von acetyl-d-carnitin zur therapeutischen behandlung von glaukom.
EP90900320A EP0446268B1 (en) 1988-12-01 1989-11-27 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma
PCT/IT1989/000076 WO1990006111A1 (en) 1988-12-01 1989-11-27 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma
JP2502051A JP2763400B2 (ja) 1988-12-01 1989-11-27 緑内障の治療処置におけるアセチルｄ―カルニチンの用途
AU46584/89A AU628116B2 (en) 1988-12-01 1989-11-27 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma
US07/442,702 US5145871A (en) 1988-12-01 1989-11-28 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma, and pharmaceutical compositions useful in such treatment
CA002004239A CA2004239C (en) 1988-12-01 1989-11-30 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma, and pharmaceutical compositions useful in such treatment
IE384089A IE62568B1 (en) 1988-12-01 1989-11-30 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma
ZA899176A ZA899176B (en) 1988-12-01 1989-11-30 Use of acetyl d-carnitine in the therapeutic treatment of glaucoma and pharmaceutical compositions useful in such treatment
GR890100797A GR1000465B (el) 1988-12-01 1989-12-01 Μεθοδος παρασκευης φαρμακευτικων συνθεσεων που περιεχουν ακετυλ d-καρνιτινη για την θεραπευτικη αγωγη του γλαυκωματος.
US07/689,527 US5432199A (en) 1988-12-01 1991-04-23 Use of acetyl D-carnitine in the therapeutic treatment of glaucoma, and pharmaceutical compositions useful in such treatment
DK199100950A DK175891B1 (da) 1988-12-01 1991-05-21 Anvendelse af acetyl-D-carnitin til fremstilling af et farmaceutisk præparat til terapeutisk behandling af glaukoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8848614A IT1224795B (it) 1988-12-01 1988-12-01 Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento

Publications (2)

Publication Number Publication Date
IT8848614A0 IT8848614A0 (it) 1988-12-01
IT1224795B true IT1224795B (it) 1990-10-24

Family

ID=11267644

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848614A IT1224795B (it) 1988-12-01 1988-12-01 Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento

Country Status (13)

Country Link
US (2) US5145871A (it)
EP (1) EP0446268B1 (it)
JP (1) JP2763400B2 (it)
KR (1) KR950004885B1 (it)
AU (1) AU628116B2 (it)
CA (1) CA2004239C (it)
DK (1) DK175891B1 (it)
ES (1) ES2040106T3 (it)
GR (1) GR1000465B (it)
IE (1) IE62568B1 (it)
IT (1) IT1224795B (it)
WO (1) WO1990006111A1 (it)
ZA (1) ZA899176B (it)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254314B (it) * 1992-03-27 1995-09-14 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1276253B1 (it) 1995-12-15 1997-10-27 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi
IT1291113B1 (it) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti Composizione nutritiva terapeutica per soggetti affetti da diabete mellito
US6090848A (en) * 1997-12-01 2000-07-18 Sigma-Tau Healthscience S.P.A. Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
US5863940A (en) 1997-12-01 1999-01-26 Sigma-Tau Healthscience S.P.A. Medicament and therapeutical method for treating idiopathic asthenozoospermia
DK0951909T4 (da) 1998-03-19 2011-01-24 Sigma Tau Ind Farmaceuti Kombinationspræparat omfattende en L-carnitin eller en alkanoyl-L-carnitin, en glycosaminoglycan og/eller bestanddel deraf
US6573299B1 (en) 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
AU2001237939A1 (en) * 2000-02-08 2001-08-20 Gulgun Tezel Methods for treating glaucoma
ES2340260T3 (es) * 2001-07-06 2010-06-01 Basf Se Procesos para la preparacion de derivados de acido 7-amino sin 3,5-diodroxi heptanoico, intermedios de los mismos y metodos para su preparacion.
RU2336902C2 (ru) 2001-10-31 2008-10-27 Алькон, Инк. Морфогенные белки кости (вмр), рецепторы вмр и связывающие вмр белки и их применение для диагностики и лечения глаукомы
ITRM20020492A1 (it) * 2002-10-01 2004-04-02 Sigma Tau Ind Farmaceuti Uso della propionil l-carnitina per la preparazione di un medicamento per il trattamento del glaucoma.
CA2515368A1 (en) * 2003-02-13 2004-08-26 Luciano Rossetti Regulation of food intake and glucose production by modulation of long-chain fatty acyl-coa levels in the hypothalamus
WO2004112756A1 (en) 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US6951658B1 (en) 2003-07-08 2005-10-04 Pearson Research & Development Limited Emu-based compositions for mental well-being and method of use
US7718697B2 (en) * 2003-12-17 2010-05-18 Alcon, Inc. Method for treating glaucoma comprising administering α-lipoic acid
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
EP2363126A1 (en) 2010-03-04 2011-09-07 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation
US9114120B2 (en) 2010-11-22 2015-08-25 Sigma-Tau Industrie Farmaceutiche Riunite, S.P.A. Therapeutical method for the treatment of the Leber optic neuropathy
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
BR112014013820A2 (pt) 2011-12-07 2017-06-13 Allergan Inc distribuição lipídica eficiente a um filme lacrimal humano usando um sistema de emulsão sensível ao sal
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
EP2783695A1 (en) 2013-03-28 2014-10-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin
AU2015353701B2 (en) 2014-11-25 2021-03-25 Allergan, Inc. Stabilized omega-3 ophthalmic compositions
IT201900002913A1 (it) 2019-03-01 2020-09-01 Nicola Pescosolido Composto utile per il trattamento del glaucoma
IT202100020729A1 (it) 2021-08-02 2023-02-02 Univ Degli Studi Di Napoli Federico Ii Preparazione combinata per il trattamento della malattia di Pompe

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1262864A (en) * 1982-09-17 1989-11-14 Clarence D. Cone Method for producing oncolysis

Also Published As

Publication number Publication date
GR1000465B (el) 1992-07-30
KR950004885B1 (ko) 1995-05-15
IE62568B1 (en) 1995-02-08
JP2763400B2 (ja) 1998-06-11
DK95091A (da) 1991-05-21
ZA899176B (en) 1990-09-26
EP0446268A1 (en) 1991-09-18
KR920702216A (ko) 1992-09-03
EP0446268B1 (en) 1993-04-14
AU4658489A (en) 1990-06-26
ES2040106T3 (es) 1993-10-01
CA2004239C (en) 1999-11-09
DK95091D0 (da) 1991-05-21
DK175891B1 (da) 2005-05-30
GR890100797A (en) 1991-03-15
US5432199A (en) 1995-07-11
IE893840L (en) 1990-06-01
AU628116B2 (en) 1992-09-10
IT8848614A0 (it) 1988-12-01
WO1990006111A1 (en) 1990-06-14
US5145871A (en) 1992-09-08
JPH04502161A (ja) 1992-04-16
CA2004239A1 (en) 1990-06-01

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971103