IT1224842B - Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso - Google Patents

Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso

Info

Publication number
IT1224842B
IT1224842B IT8848717A IT4871788A IT1224842B IT 1224842 B IT1224842 B IT 1224842B IT 8848717 A IT8848717 A IT 8848717A IT 4871788 A IT4871788 A IT 4871788A IT 1224842 B IT1224842 B IT 1224842B
Authority
IT
Italy
Prior art keywords
nervous system
therapeutic treatment
carnitine derivatives
degenerative alterations
alterations
Prior art date
Application number
IT8848717A
Other languages
English (en)
Other versions
IT8848717A0 (it
Inventor
Cavazza Claudio
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IT8848717A0 publication Critical patent/IT8848717A0/it
Priority to IT8848717A priority Critical patent/IT1224842B/it
Priority to ES89830544T priority patent/ES2058596T3/es
Priority to AT89830544T priority patent/ATE92316T1/de
Priority to EP89830544A priority patent/EP0376899B1/en
Priority to DE89830544T priority patent/DE68908145T2/de
Priority to US07/451,253 priority patent/US5043355A/en
Priority to ZA899802A priority patent/ZA899802B/xx
Priority to JP1338034A priority patent/JP2828293B2/ja
Application granted granted Critical
Publication of IT1224842B publication Critical patent/IT1224842B/it
Priority to HK98104941A priority patent/HK1005849A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8848717A 1988-12-27 1988-12-27 Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso IT1224842B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8848717A IT1224842B (it) 1988-12-27 1988-12-27 Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
DE89830544T DE68908145T2 (de) 1988-12-27 1989-12-13 Verwendung von L-Carnitinderivaten zur Herstellung eines Arzneimittels zur therapeutischen Behandlung von peripheren Neuropathien.
AT89830544T ATE92316T1 (de) 1988-12-27 1989-12-13 Verwendung von l-carnitinderivaten zur herstellung eines arzneimittels zur therapeutischen behandlung von peripheren neuropathien.
EP89830544A EP0376899B1 (en) 1988-12-27 1989-12-13 Use of l-carnitine derivatives for the manufacture of a medicament for the therapeutical treatment of peripheral neuropathies
ES89830544T ES2058596T3 (es) 1988-12-27 1989-12-13 Empleo de derivados de l-carnitina en el tratamiento terapeutico de alteraciones degenerativas del sistema nervioso.
US07/451,253 US5043355A (en) 1988-12-27 1989-12-15 Use of L-carnitine derivatives in the therapeutical treatment of peripheral neuropathies
ZA899802A ZA899802B (en) 1988-12-27 1989-12-21 Use of l-carnitine derivatives in the therapeutic treatment of degenerative alterations of the nervous system
JP1338034A JP2828293B2 (ja) 1988-12-27 1989-12-26 神経系退行性変質のためのｌ―カルニチン誘導体治療剤
HK98104941A HK1005849A1 (en) 1988-12-27 1998-06-05 Use of l-carnitine derivatives for the manufacture of a medicament for the therapeutical treatment of peripheral neuropathies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8848717A IT1224842B (it) 1988-12-27 1988-12-27 Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso

Publications (2)

Publication Number Publication Date
IT8848717A0 IT8848717A0 (it) 1988-12-27
IT1224842B true IT1224842B (it) 1990-10-24

Family

ID=11268228

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848717A IT1224842B (it) 1988-12-27 1988-12-27 Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso

Country Status (9)

Country Link
US (1) US5043355A (it)
EP (1) EP0376899B1 (it)
JP (1) JP2828293B2 (it)
AT (1) ATE92316T1 (it)
DE (1) DE68908145T2 (it)
ES (1) ES2058596T3 (it)
HK (1) HK1005849A1 (it)
IT (1) IT1224842B (it)
ZA (1) ZA899802B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245699B (it) * 1991-05-29 1994-10-14 Sigma Tau Ind Farmaceuti Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi
IT1254314B (it) * 1992-03-27 1995-09-14 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
IT1277898B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1276253B1 (it) 1995-12-15 1997-10-27 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi
IT1283951B1 (it) * 1996-03-15 1998-05-07 Mendes Srl Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di
IT1291113B1 (it) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti Composizione nutritiva terapeutica per soggetti affetti da diabete mellito
US6090848A (en) * 1997-12-01 2000-07-18 Sigma-Tau Healthscience S.P.A. Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
US5863940A (en) 1997-12-01 1999-01-26 Sigma-Tau Healthscience S.P.A. Medicament and therapeutical method for treating idiopathic asthenozoospermia
ES2210705T5 (es) 1998-03-19 2011-02-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composición combinada que comprende una l-carnitina o una alcanoil-l-carnitina, un glucosaminoglucano y/o un constituyente del mismo.
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
ITRM20040327A1 (it) * 2004-07-01 2004-10-01 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
JP5047507B2 (ja) * 2005-09-30 2012-10-10 昭和電工株式会社 カルニチン誘導体及びその塩、皮膚外用剤ならびに化粧料
US7842726B2 (en) * 2005-09-30 2010-11-30 Showa Denko K.K. Carnitine derivative, salt thereof, external skin preparation and cosmetic material
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
WO2020092243A1 (en) * 2018-10-29 2020-05-07 Lonza Inc. Method and composition for increasing the bioavailability of carnitine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903579A1 (de) * 1978-02-03 1979-08-09 Sigma Tau Ind Farmaceuti Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel
IT1206954B (it) * 1979-02-12 1989-05-17 Sigma Tau Ind Farmaceuti Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche
US4346107A (en) * 1979-02-12 1982-08-24 Claudio Cavazza Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1150396B (it) * 1982-12-09 1986-12-10 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico di miopa tie e distrofie muscolari
IT1181682B (it) * 1985-06-11 1987-09-30 Sigma Tau Ind Farmaceuti Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto
IT1208753B (it) * 1986-07-02 1989-07-10 Sigma Tau Ind Farmaceuti L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche

Also Published As

Publication number Publication date
ATE92316T1 (de) 1993-08-15
JP2828293B2 (ja) 1998-11-25
HK1005849A1 (en) 1999-01-29
DE68908145D1 (de) 1993-09-09
ES2058596T3 (es) 1994-11-01
IT8848717A0 (it) 1988-12-27
US5043355A (en) 1991-08-27
JPH02207020A (ja) 1990-08-16
EP0376899A2 (en) 1990-07-04
ZA899802B (en) 1990-11-28
DE68908145T2 (de) 1993-11-25
EP0376899A3 (en) 1991-09-18
EP0376899B1 (en) 1993-08-04

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971103