ITRM20040327A1 - Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. - Google Patents

Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.

Info

Publication number
ITRM20040327A1
ITRM20040327A1 IT000327A ITRM20040327A ITRM20040327A1 IT RM20040327 A1 ITRM20040327 A1 IT RM20040327A1 IT 000327 A IT000327 A IT 000327A IT RM20040327 A ITRM20040327 A IT RM20040327A IT RM20040327 A1 ITRM20040327 A1 IT RM20040327A1
Authority
IT
Italy
Prior art keywords
carnitine
medication
acetyl
preparation
treatment
Prior art date
Application number
IT000327A
Other languages
English (en)
Inventor
Antonino Amato
Menotti Calvani
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT000327A priority Critical patent/ITRM20040327A1/it
Publication of ITRM20040327A1 publication Critical patent/ITRM20040327A1/it
Priority to US10/969,217 priority patent/US20060004095A1/en
Priority to CA2570268A priority patent/CA2570268C/en
Priority to ES05730316.6T priority patent/ES2532497T3/es
Priority to DK05730316T priority patent/DK1761257T3/en
Priority to KR1020077000584A priority patent/KR101176347B1/ko
Priority to EP05730316.6A priority patent/EP1761257B1/en
Priority to MXPA06014907A priority patent/MXPA06014907A/es
Priority to SI200531946T priority patent/SI1761257T1/sl
Priority to PT57303166T priority patent/PT1761257E/pt
Priority to JP2007519628A priority patent/JP5519907B2/ja
Priority to US11/570,484 priority patent/US20070213408A1/en
Priority to PCT/EP2005/003557 priority patent/WO2006002698A1/en
Priority to PL05730316T priority patent/PL1761257T3/pl
Priority to CY20151100283T priority patent/CY1116171T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
IT000327A 2004-07-01 2004-07-01 Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. ITRM20040327A1 (it)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT000327A ITRM20040327A1 (it) 2004-07-01 2004-07-01 Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
US10/969,217 US20060004095A1 (en) 2004-07-01 2004-10-21 Use of acetyl L-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients
PL05730316T PL1761257T3 (pl) 2004-07-01 2005-04-05 Zastosowanie acetylo-L-karnityny podczas przygotowania leku do leczenia bólu neuropatycznego u pacjentów cukrzycowych
EP05730316.6A EP1761257B1 (en) 2004-07-01 2005-04-05 Use of acetyl l-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients
ES05730316.6T ES2532497T3 (es) 2004-07-01 2005-04-05 Uso de acetil-L-carnitina para la preparación de un medicamento para el tratamiento del dolor neuropático en pacientes diabéticos
DK05730316T DK1761257T3 (en) 2004-07-01 2005-04-05 Use of acetyl L-carnitine in the manufacture of a medicament for the treatment of neuropathic pain in diabetic patients
KR1020077000584A KR101176347B1 (ko) 2004-07-01 2005-04-05 당뇨병 환자의 신경병 통증 치료용 약제의 제조를 위한아세틸 엘 카르니틴의 용도
CA2570268A CA2570268C (en) 2004-07-01 2005-04-05 Use of acetyl l-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients
MXPA06014907A MXPA06014907A (es) 2004-07-01 2005-04-05 Uso de acetil l-carnitina para preparacion de medicina para tratamiento de dolor neuropatico en pacientes diabeticos.
SI200531946T SI1761257T1 (sl) 2004-07-01 2005-04-05 Uporaba acetil-L-karnitina za pripravo zdravila za zdravljenje nevropatske bolečine pri diabetičnih bolnikih
PT57303166T PT1761257E (pt) 2004-07-01 2005-04-05 O uso de acetil l-carnitina para a preparação de um medicamento para o tratamento de dor neuropática em pacientes diabéticos
JP2007519628A JP5519907B2 (ja) 2004-07-01 2005-04-05 糖尿病患者における神経因性疼痛の治療用医薬の調製のためのアセチルl−カルニチンの使用
US11/570,484 US20070213408A1 (en) 2004-07-01 2005-04-05 Use of Acetyl L-Carnitine for the Preparation of a Medicine for the Treatment of Neuropathic Pain in Diabetic Patients
PCT/EP2005/003557 WO2006002698A1 (en) 2004-07-01 2005-04-05 Use of acetyl l-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients
CY20151100283T CY1116171T1 (el) 2004-07-01 2015-03-23 Χρηση ακετυλο-l-καρνιτινης για την παρασκευη φαρμακου για τη θεραπευτικη αγωγη του νευροπαθητικου πονου σε διαβητικους ασθενεις

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000327A ITRM20040327A1 (it) 2004-07-01 2004-07-01 Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.

Publications (1)

Publication Number Publication Date
ITRM20040327A1 true ITRM20040327A1 (it) 2004-10-01

Family

ID=34965656

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000327A ITRM20040327A1 (it) 2004-07-01 2004-07-01 Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.

Country Status (14)

Country Link
US (2) US20060004095A1 (it)
EP (1) EP1761257B1 (it)
JP (1) JP5519907B2 (it)
KR (1) KR101176347B1 (it)
CA (1) CA2570268C (it)
CY (1) CY1116171T1 (it)
DK (1) DK1761257T3 (it)
ES (1) ES2532497T3 (it)
IT (1) ITRM20040327A1 (it)
MX (1) MXPA06014907A (it)
PL (1) PL1761257T3 (it)
PT (1) PT1761257E (it)
SI (1) SI1761257T1 (it)
WO (1) WO2006002698A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1341813B1 (en) * 2000-12-15 2006-09-13 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of l-carnitine as stabilizing agent of proteins
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1133010B (it) * 1980-05-15 1986-07-09 Sigma Tau Ind Farmaceuti Metodo terapuetico per il trattamento del diabete mellito a insorgenza giovanile e composizione farmaceutica per tale metodo
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
US5827886A (en) * 1997-05-07 1998-10-27 Thione International, Inc. Composition for relief of arthritis-induced symptoms
IT1294227B1 (it) * 1997-08-01 1999-03-24 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
IT1306178B1 (it) * 1999-07-27 2001-05-30 Sigma Tau Ind Farmaceuti Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da
ITRM20010294A1 (it) * 2001-05-29 2002-11-29 Sigma Tau Ind Farmaceuti Uso della acetil l-carnetina in associazione con la biotina per il trattamento di pazienti affetti da diabete mellito di tipo ii insulino re

Also Published As

Publication number Publication date
CY1116171T1 (el) 2017-02-08
US20060004095A1 (en) 2006-01-05
PL1761257T3 (pl) 2015-06-30
US20070213408A1 (en) 2007-09-13
JP2008505134A (ja) 2008-02-21
WO2006002698A1 (en) 2006-01-12
KR101176347B1 (ko) 2012-08-24
EP1761257B1 (en) 2014-12-31
JP5519907B2 (ja) 2014-06-11
EP1761257A1 (en) 2007-03-14
ES2532497T3 (es) 2015-03-27
CA2570268C (en) 2013-10-15
CA2570268A1 (en) 2006-01-12
KR20070042963A (ko) 2007-04-24
DK1761257T3 (en) 2015-03-23
SI1761257T1 (sl) 2015-04-30
MXPA06014907A (es) 2007-03-21
PT1761257E (pt) 2015-04-14

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