IT1306178B1 - Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da - Google Patents

Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da

Info

Publication number
IT1306178B1
IT1306178B1 IT1999RM000480A ITRM990480A IT1306178B1 IT 1306178 B1 IT1306178 B1 IT 1306178B1 IT 1999RM000480 A IT1999RM000480 A IT 1999RM000480A IT RM990480 A ITRM990480 A IT RM990480A IT 1306178 B1 IT1306178 B1 IT 1306178B1
Authority
IT
Italy
Prior art keywords
alcanoil
carnitine
derivatives
patient
preparation
Prior art date
Application number
IT1999RM000480A
Other languages
English (en)
Inventor
Claudio Cavazza
Giovanni Valentini
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT1999RM000480A priority Critical patent/IT1306178B1/it
Publication of ITRM990480A0 publication Critical patent/ITRM990480A0/it
Priority to PCT/IT2000/000288 priority patent/WO2001007038A2/en
Priority to US10/019,627 priority patent/US6696492B1/en
Priority to MXPA02000912A priority patent/MXPA02000912A/es
Priority to CA002376033A priority patent/CA2376033C/en
Priority to AU58474/00A priority patent/AU5847400A/en
Publication of ITRM990480A1 publication Critical patent/ITRM990480A1/it
Application granted granted Critical
Publication of IT1306178B1 publication Critical patent/IT1306178B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT1999RM000480A 1999-07-27 1999-07-27 Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da IT1306178B1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT1999RM000480A IT1306178B1 (it) 1999-07-27 1999-07-27 Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da
PCT/IT2000/000288 WO2001007038A2 (en) 1999-07-27 2000-07-12 Use of l-carnitine and its alkanoyl derivatives for the preparation of a medicament useful for the treatment of patients suffering from diabetic and/or dysmetabolic nephropathy
US10/019,627 US6696492B1 (en) 1999-07-27 2000-07-12 Use of L carnitine and its alkanoyl dervatives for the preparation of a medicament useful for the treatment of patients suffering from diabetic and/or dysmetabolic nephropathy
MXPA02000912A MXPA02000912A (es) 1999-07-27 2000-07-12 Uso de l-carnitina y sus derivados alcanoilo para la preparacion de un medicamento util para el tratamiento de pacientes que sufren nefropatias diabeticas o por insuficiencia metabolica.
CA002376033A CA2376033C (en) 1999-07-27 2000-07-12 Use of l-carnitine and its alkanoyl derivatives for the preparation of a medicament useful for the treatment of patients suffering from diabetic and/or dysmetabolic nephropathy
AU58474/00A AU5847400A (en) 1999-07-27 2000-07-12 Use of l-carnitine and its alkanoyl derivatives for the preparation of a medicament useful for the treatment of patients suffering from diabetic and/or dysmetabolic nephropathy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999RM000480A IT1306178B1 (it) 1999-07-27 1999-07-27 Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da

Publications (3)

Publication Number Publication Date
ITRM990480A0 ITRM990480A0 (it) 1999-07-27
ITRM990480A1 ITRM990480A1 (it) 2001-01-27
IT1306178B1 true IT1306178B1 (it) 2001-05-30

Family

ID=11406907

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999RM000480A IT1306178B1 (it) 1999-07-27 1999-07-27 Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da

Country Status (6)

Country Link
US (1) US6696492B1 (it)
AU (1) AU5847400A (it)
CA (1) CA2376033C (it)
IT (1) IT1306178B1 (it)
MX (1) MXPA02000912A (it)
WO (1) WO2001007038A2 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7011977B2 (en) * 1999-01-30 2006-03-14 Sigma-Tau Pharmaceuticals, Inc. Quantification of carnitine levels in dialysis patients
US7238531B2 (en) * 1999-01-30 2007-07-03 Pediatrix Screening, Inc. Method for interpreting tandem mass spectrometry data for clinical diagnosis
US7297545B2 (en) * 1999-01-30 2007-11-20 Pediatrix Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor
ITRM20040327A1 (it) * 2004-07-01 2004-10-01 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
CN102038671B (zh) * 2010-06-29 2012-07-04 辽宁思百得医药科技有限公司 包含左卡尼汀和羟苯磺酸盐的药物组合物
ES2385169B1 (es) * 2010-12-22 2013-09-23 Servicio Andaluz De Salud Uso de la l-carnitina y sus composiciones, para el tratamiento y la prevención del daño renal.
SE542106C2 (en) * 2016-08-26 2020-02-25 Atif M Dabdoub Dietary macro/micronutritional supplement for patients undergoing kidney dialysis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903558C2 (de) * 1978-02-03 1994-09-01 Sigma Tau Ind Farmaceuti Verwendung von L-Carnitin
IT1133010B (it) * 1980-05-15 1986-07-09 Sigma Tau Ind Farmaceuti Metodo terapuetico per il trattamento del diabete mellito a insorgenza giovanile e composizione farmaceutica per tale metodo
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
US5614224A (en) * 1995-04-20 1997-03-25 Womack; Rick W. Nutritional supplement for diabetics
IT1290801B1 (it) 1996-07-05 1998-12-11 Mendes Srl Uso della acetil l-carnitina, della isovaleril l-carnitina, della propionil l-carnitina o dei loro sali farmacologicamente accettabili
WO1998033494A1 (en) * 1997-02-04 1998-08-06 Kosbab John V Compositions and methods for prevention and treatment of vascular degenerative diseases
IT1294227B1 (it) * 1997-08-01 1999-03-24 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
US6429230B1 (en) * 2000-01-19 2002-08-06 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis
US6335369B1 (en) * 2000-01-19 2002-01-01 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Treating chronic uremic patients undergoing periodical dialysis

Also Published As

Publication number Publication date
AU5847400A (en) 2001-02-13
WO2001007038A3 (en) 2002-02-07
US6696492B1 (en) 2004-02-24
WO2001007038A2 (en) 2001-02-01
CA2376033A1 (en) 2001-02-01
ITRM990480A1 (it) 2001-01-27
CA2376033C (en) 2009-04-07
MXPA02000912A (es) 2002-10-23
ITRM990480A0 (it) 1999-07-27

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